Sunday, June 3, 2007

7. Drugs/Medicines

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Apricot Seeds

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Coconut Oil, Very High in Lauric Fatty Acid Which Has Many Health Uses

"Black Seed:" Nigella Sativa; cancer treatment

 




















Tumeric














(different forms of medicine; are you given options or are you forced to consume certain medicines by those who have limited your choices and even hidden and outlawed cheap and effective remedies?)

For two hundred years, there has been an economic competition from the empirics/homeopaths that caused the allopathics to found the American Medical Association. This organization has been found guilty of conspiracy before to repress alternatives. For more details see below the film Hoxsey: How Healing Becomes a Crime. I quote from this film's narration:

"The war of money between Hoxsey and the doctors is another old story in medicine. In the 1800s, doctors tried to stop the popular empirics from collecting their fees by denouncing them as quacks. Economic competition from the empirics caused the doctors to found the AMA. But the AMA was a small trade association without political clout, and the balance of power remained equal until the turn of the century. Then, new medical treatments emerged that were potentially very profitable. Then the AMA joined with strong financial forces to transform medicine into an industry. The fortunes of Carnegie, Morgan, and Rockefeller financed surgery, radiation, and synthetic drugs. They were to become the economic foundations of the new medical economy. Ironically, John D. Rockefeller himself used only an empirical homeopath while investing in allopathic medicine. Surgery became viable [for the first time without potential secondary infection deaths] with anesthesia and infection control, and doctors advocated expensive radical operations. These in turn produced the need for a large, and lucrative hospital system. The allopaths also discovered a new toxic mineral, radium..." etc. 1:03:35 into the film.

Furthermore, it narrates:

"The AMA targeted Harry Hoxsey as public quack #1. But by the 1940s, its quack files had swelled to include 300,000 names. Hoxsey had long charged a conspiracy. His solitary voice was now echoed by many others. In the 1950s, a Congressional committee came to the same conclusion. The Fitzgerald Report to Congress named at least a dozen other promising cancer treatments seemingly blocked by organized medicine. Their proponents were mostly doctors of high reputation. The treatments were immunological or nutritional. Dismissing them as quackery, were panels of surgeons or radiation therapists. The congressional report emphasized two outstanding cases of alleged suppression: Harry Hoxsey and Dr. Andrew C. Ivy. If Hoxsey fit the [stereotypical] image of a quack [without being one], Dr. Ivy certainly did not. [He was the organizer of the Bethesda Navel Medical Research Institute, former national director of the National Cancer Advisory Council, Vice President of the University of Illinois, and a former board member of the American Cancer Society; he was associating himself with the drug Krebiozen (more information available from the book Krebiozen: 13 Years of Confict (1963)).

The Hoxsey film documents a disturbing pattern at least three times: where the AMA doctors attempted to buy a workable cancer treatment, though were refused by the inventors. Then the AMA sets out to destroy through its political institutional allies the alternative it was unable to profit from, though attempted to. There were Congressional investigations into AMA fraud in 1953, 1963, and 1981 the film documents as well.

Moreover, the American medical association was found guilty of ‘conspiracy’ to destroy the chiropractic profession in August, 1987.

Other medicines condemned without investigation include:

HERBAL

Chapparal tea, University of Utah

Essiac
Renee Caisse, RN

Gerson Therapy
Max Gerson, MD

Vitamin C
Linus Pauling, MD; Nobel Laureate

Macrobiotics
Kichio Kushi


IMMUNOLOGY

Bacteriophage
Robert F. Lincoln

Coley’s Toxins
William Coley, MD

Coffey-Humber Extract
Walter Coffey and John Humber MD's

Glover’s Serum
Thomas J. Glover, MD

Glyoxylide
William F. Koch, MD

Hydrazine Sulfate
Joseph Gold, M.D.

Immuno-Augumentive Therapy
Lawrence Burton Ph.D.

Krebiozen
Andrew C. Ivy, M.D.

Laetrile (featured in the film linked below)
Earnst T. Krebs, MD

Livingston Vaccine
Virginia Livingston

Ozias Treatment
Charles Ozias, MD

Revici Method
Emmanuel Revici, PhD

Rife Microscope
Royal Raymond Rife


I recommend the Hoxsey film and the following one for those interested in health freedom choice and in researching ongoing repressive politics against free nutritional therapies --whether in the United States and in many cases, worldwide.

Hoxsey - How Healing Becomes A Crime (Alternative Cancer Cure)
1:23:32 min


This documentary concerns Harry M. Hoxsey, the former coal miner whose family's herbal recipe has brought about claims of a cancer cure. Starting in 1924 with his first clinic, he expanded to 17 states by the mid 1950s, along the way constantly battling [the poor track record of] organized medicine that [attempted to] label him a charlatan. Hoxsey's supporters point out he was the victim of arrests, or "quackdowns" spearheaded by the proponents of established medical practices. Interviews of patients satisfied with the results of the controversial treatment are balanced with physicians from the FDA and the AMA. A clinic in Tijuana, Mexico claims an 80% success rate....What is apparent is that cancer continues to be one of humankind's more dreaded diseases, and that political and economic forces dominate research and development.


Another film:

G. Edward Griffin - A World Without Cancer - The Story Of Vitamin B17
55 min - Apr 7, 2006

"G. Edward Griffin marshals the evidence that cancer is a deficiency disease--like scurvy or pellagra--aggravated by the lack of an essential food compound in modern man's diet. That substance is vitamin B17. In its purified form developed for cancer therapy, it is known as Laetrile. This story is not approved by orthodox medicine. The FDA, the AMA, and The American Cancer Society have labeled it fraud and quackery. Yet the evidence is clear that here, at last, is the final answer to the cancer riddle. Why has orthodox medicine waged war against this non-drug approach? The author contends that the answer is to be found, not in science, but in politics--and is based upon the hidden economic and power agenda of those who dominate the medical establishment.

With billions of dollars spent each year on research, with other billions taken in on the sale of cancer-related drugs, and with fund-raising at an all-time high, there are now more people making a living from cancer than dying from it. If the solution should be found in a simple vitamin, this gigantic industry could be wiped out over night. The result is that the politics of cancer therapy is more complicated than the science."




I additionally recommend investigative journalist Phillip Day's book on nutritional health research. Most of this information has been hidden by self-interested medical establishments because cheap treatments of many things are well known, though they have been hidden from the public. See the book Health Wars.

And mycelium is a far more efficient and effective form of (free, unpatentable) form of medicine. It has several billion years of field testing, so it works on mycelium as well as us--because both humans and mycelium have an uncanny similarity biologically for what keeps us alive and healthy. Therefore, free, unpatentable mycelium abstracts can make a true revolution against the synthetic, deadly, hyper-expensive treatments. Note Paul Stamets research showing that mycelium is hundreds of times more effective than any synthetic drug on the market.

Mycelium is an excellent base for starting the commodity ecology, because literally it was the basis for all land base life: the first land dwellers that prepared everything chemically for soil formation and self-medicine against bacteria and other viral pests. See this short stunning video, below.

Paul Stamets: 6 ways mushrooms can save the world (17 minutes)
http://www.ted.com/talks/view/id/258



"Entrepreneurial mycologist Paul Stamets seeks to rescue the study of mushrooms from forest gourmets and psychedelic warlords. The focus of Stamets' research is the Northwest's native fungal genome, mycelium, but along the way he has filed 22 patents for mushroom-related technologies, including pesticidal fungi that trick insects into eating them, and mushrooms that can break down the neurotoxins used in nerve gas. There are cosmic implications as well. Stamets believes we could terraform other worlds in our galaxy by sowing a mix of fungal spores and other seeds to create an ecological footprint on a new planet."

Re-basing commodity ecology, the ecologizing of human commodification, on mycelium seems the sounded basis to start. Moreover, it is probably to be expected because mycelium was the first arriving "'life organ' of ecology" that these species would be an integral start for life--and for other commodity ecology paths. It has THE MOST cross-connects or overlaps SO FAR with leads into other categories. It connects very well with:

58. Remediation
16. Herbicides/Pesticides
6. Soils/Dirt/Hydroponics
5. Garbage/Garbage disposal
7. Drugs/Medicines
11. Mycelium based food
72. Packing Materials (for seeding forests, mycelium and seeds embedded)

THAT means mycelium's many local multiple consumptive positional uses makes it a good place to start upon the commodity ecology for branching in multiple directions from this locus. He says 6 ideas. I count seven. Really, all the difficulties with sustainability are already solved. It merely means putting all the pieces together combined with challenging the corrupt developmentalism with the bioregional state institutional arrangements, challenging the arrangements that keep sustainability, sustainable politics, and territorial states from happening.

Issues like the material corruptions above are why the bioregional state requires 'commodity reform' as much as checks and balances against existing corruptions of democratic political institution that have maintained this corruption. Such changes have a huge backing since it expresses supermajorities that support more democratic feedback into developmental politics.

Politics is always over developmental directions--some more representative (like the bioregional state) than others.

In the definition of the bioregional state:

Bioregional democracy (or the Bioregional State) is a set of electoral reforms and commodity reforms designed to force the political process in a democracy to better represent concerns about the economy, the body, and environmental concerns (e.g. water quality), toward developmental paths that are locally prioritized and tailored to different areas for their own specific interests of sustainability and durability. This movement is variously called bioregional democracy, watershed cooperation, or bioregional representation, or one of various other similar names--all of which denote democratic control of a natural commons and local jurisdictional dominance in any economic developmental path decisions—while not removing more generalized civil rights protections of a larger national state.

Other temporary enhancements to encourage human self-healing seem ethically sound, like much of electromedicine:


VIBE Machine Interview With Gene Koonce
18:33 min.

http://youtube.com/watch?v=XBcPAyo9kdg



Other examples of electromedicine/frequency medicine are Dr. Peter Guy Manners' Cymatic Instrument (based on audio frequencies instead of electrical frequencies), or a Chinese Qigong infrasound machine utilized in China, based on infrasound 'taped' from Qigong masters and played back 'at' hospital patients for healing. This enters an area that is quite interdiciplinary and based on knowing about the bioelectric and bio-audial frameworks of DNA activation and biofrequency conditions of health in the human body and reachiving it through sympathetically inducing in the body enough of a frequency effect to allow the body to heal itself naturally.

However, when other 'natural' additions or techniques are irreversible or inequitably available as commodities we are off into a 'brave new world' of ethical dangers. For instance, if bodily regeneration is only available for the rich in the future, it would create a class-based hive society. The future is here and it requires an equitably available preventative medicine based regime.

Alan Russell on regenerating our bodies
19:37 min.

http://www.ted.com/index.php/talks/view/id/142



Aubrey de Grey says we can avoid aging
23:31 min.

http://www.ted.com/index.php/talks/view/id/39



Such are the promise and perils of this category of human commodities of medicines: will medicine maintain equality among humans or only become another form of inequality being reified biologically, with different life chances based on access to these regenerative medical ideas? Will we be repressively limited access to free nutritional therapies by international corporations that don't like the competition with their expensive products? This is how the Codex Alimentarius from the WTO is attemping to outlaw nutrituional therapies by 2009. You should watch this: see a nutritionist's videotaped talk concerning GLOBAL threats to our health and medical freedom due to the WTO's repressive Codex Alimentarius that would outlaw many free nutritional therapies to benefit the international pharmaceutial manufacturer sales, at this link.

Only if medicine is [1] entirely opt-in/opt-out, [2] reversible without harm, and [3] equally available would seem to be three critical caveats that avoid any unknown feedback effects associated with the famous phrase "you know, it was a great idea, er, at the time, until..."

Just to keep in mind what is known for free therapy, though systemic interests want to keep from everyone:

Pot Shrinks Tumors; Government Knew in '74

In 1974 researchers learned that THC, the active chemical in marijuana, shrank or destroyed brain tumors in test mice. But the DEA quickly shut down the study and destroyed its results, which were never replicated -- until now.

May 31, 2000

The term medical marijuana took on dramatic new meaning in February, 2000 when researchers in Madrid announced they had destroyed incurable brain tumors in rats by injecting them with THC, the active ingredient in cannabis.

The Madrid study marks only the second time that THC has been administered to tumor-bearing animals; the first was a Virginia investigation 26 years ago. In both studies, the THC shrank or destroyed tumors in a majority of the test subjects.

Most Americans don't know anything about the Madrid discovery. Virtually no major U.S. newspapers carried the story, which ran only once on the AP and UPI news wires, on Feb. 29, 2000.

The ominous part is that this isn't the first time scientists have discovered that THC shrinks tumors. In 1974 researchers at the Medical College of Virginia, who had been funded by the National Institute of Health to find evidence that marijuana damages the immune system, found instead that THC slowed the growth of three kinds of cancer in mice -- lung and breast cancer, and a virus-induced leukemia.

The DEA quickly shut down the Virginia study and all further cannabis/tumor research, according to Jack Herer, who reports on the events in his book, "The Emperor Wears No Clothes." In 1976 President Gerald Ford put an end to all public cannabis research and granted exclusive research rights to major pharmaceutical companies, who set out -- unsuccessfully -- to develop synthetic forms of THC that would deliver all the medical benefits without the "high."

The Madrid researchers reported in the March issue of "Nature Medicine" that they injected the brains of 45 rats with cancer cells, producing tumors whose presence they confirmed through magnetic resonance imaging (MRI). On the 12th day they injected 15 of the rats with THC and 15 with Win-55,212-2 a synthetic compound similar to THC. "All the rats left untreated uniformly died 12-18 days after glioma (brain cancer) cell inoculation ... Cannabinoid (THC)-treated rats survived significantly longer than control rats. THC administration was ineffective in three rats, which died by days 16-18. Nine of the THC-treated rats surpassed the time of death of untreated rats, and survived up to 19-35 days. Moreover, the tumor was completely eradicated in three of the treated rats." The rats treated with Win-55,212-2 showed similar results.

The Spanish researchers, led by Dr. Manuel Guzman of Complutense University, also irrigated healthy rats' brains with large doses of THC for seven days, to test for harmful biochemical or neurological effects. They found none.

"Careful MRI analysis of all those tumor-free rats showed no sign of damage related to necrosis, edema, infection or trauma ... We also examined other potential side effects of cannabinoid administration. In both tumor-free and tumor-bearing rats, cannabinoid administration induced no substantial change in behavioral parameters such as motor coordination or physical activity. Food and water intake as well as body weight gain were unaffected during and after cannabinoid delivery. Likewise, the general hematological profiles of cannabinoid-treated rats were normal. Thus, neither biochemical parameters nor markers of tissue damage changed substantially during the 7-day delivery period or for at least 2 months after cannabinoid treatment ended."

Guzman's investigation is the only time since the 1974 Virginia study that THC has been administered to live tumor-bearing animals. (The Spanish researchers cite a 1998 study in which cannabinoids inhibited breast cancer cell proliferation, but that was a "petri dish" experiment that didn't involve live subjects.)

In an email interview for this story, the Madrid researcher said he had heard of the Virginia study, but had never been able to locate literature on it. Hence, the Nature Medicine article characterizes the new study as the first on tumor-laden animals and doesn't cite the 1974 Virginia investigation.

"I am aware of the existence of that research. In fact I have attempted many times to obtain the journal article on the original investigation by these people, but it has proven impossible." Guzman said.

In 1983 the Reagan/Bush Administration tried to persuade American universities and researchers to destroy all 1966-76 cannabis research work, including compendiums in libraries, reports Jack Herer, who states, "We know that large amounts of information have since disappeared."

Guzman provided the title of the work -- "Antineoplastic activity of cannabinoids," an article in a 1975 Journal of the National Cancer Institute -- and this writer obtained a copy at the University of California medical school library in Davis and faxed it to Madrid.

The summary of the Virginia study begins, "Lewis lung adenocarcinoma growth was retarded by the oral administration of tetrahydrocannabinol (THC) and cannabinol (CBN)" -- two types of cannabinoids, a family of active components in marijuana. "Mice treated for 20 consecutive days with THC and CBN had reduced primary tumor size."

The 1975 journal article doesn't mention breast cancer tumors, which featured in the only newspaper story ever to appear about the 1974 study -- in the Local section of the Washington Post on August 18, 1974. Under the headline, "Cancer Curb Is Studied," it read in part:

"The active chemical agent in marijuana curbs the growth of three kinds of cancer in mice and may also suppress the immunity reaction that causes rejection of organ transplants, a Medical College of Virginia team has discovered." The researchers "found that THC slowed the growth of lung cancers, breast cancers and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent."

Guzman, writing from Madrid, was eloquent in his response after this writer faxed him the clipping from the Washington Post of a quarter century ago. In translation, he wrote:

"It is extremely interesting to me, the hope that the project seemed to awaken at that moment, and the sad evolution of events during the years following the discovery, until now we once again Œdraw back the veil‚ over the anti-tumoral power of THC, twenty-five years later. Unfortunately, the world bumps along between such moments of hope and long periods of intellectual castration."

News coverage of the Madrid discovery has been virtually nonexistent in this country. The news broke quietly on Feb. 29, 2000 with a story that ran once on the UPI wire about the Nature Medicine article. This writer stumbled on it through a link that appeared briefly on the Drudge Report web page. The New York Times, Washington Post and Los Angeles Times all ignored the story, even though its newsworthiness is indisputable: a benign substance occurring in nature destroys deadly brain tumors.

Raymond Cushing is a journalist, musician and filmmaker. This article was named by Project Censored as a "Top Censored Story of 2000."

Avoid the "run from the cure" described in the following film. Instead, run to the cure(s):

RUN FROM THE CURE - The Rick Simpson Story, Full Version [the curing powers of natural, unpatentable, hemp oil]
58:02 min



"They let the genie out of the bottle with this one, and the big money can't put it back in." A Film By Christian Laurette - After a serious head injury in 1997, Rick Simpson sought relief from his medical condition through the use of medicinal hemp oil. When Rick discovered that the hemp oil (with its high concentration of T.H.C.) cured cancers and other illnesses, he tried to share it with as many people as he could free of charge - curing and controlling literally hundreds of people's illnesses... but when the story went public, the long arm of the law snatched the medicine - leaving potentially thousands of people without their cancer treatments - and leaving Rick with unconsitutional charges of possessing and trafficking marijuana! [The corrupt Canadian government attacks everyone in sight related to this, even its own military curing soldiers of various ailments far better than the expensive "required" allopathic medicines that make drug companies richer and people sicker with side effects, with little cure in sight, and most cures withdrawn by a money-model base of medicine, instead of cures put in sight by a healing-model base of medicine.]

Canada is in the middle of a cancer epidemic. Meet the people who were not allowed to testify on Rick's behalf at the Supreme Court of Canada's Infamous Rick Simpson Trial on September 10, 2007...INCLUDING A MAN WHO WAS CURED OF TERMINAL CANCER USING HEMP OIL! IF YOU SEE ONLY ONE DOCUMENTARY THIS YEAR...MAKE IT THIS ONE! Download the whole movie for free and share it at http://www.phoenixtearsmovie.com VIEW ALL 7 FILES AT http://www.youtube.com/chrychek - Please make a donation in any amount using the donate button on phoenixtears.ca and together we can CRUSH CANCER without government support. The world deserves a cure for cancer. Please support this world-changing cause. http://www.phoenixtears.ca ; http://www.phoenixtearsmovie.com ."

"Black Seed"

"Black Seed:" Nigella Sativa

Black seed is also known as Nigella sativa, black cumin, kalonji, haba al barakah and gizhah.

It has been used for over 2000 years as a relief for all disease and recently it has been studied extensively for cancer, skin disease and inflammation disorders.

Originally black seeds were used for migraines, allergies and acne disorders, but as scientists begin to realize its potential for curing cancer, the research began:
Pancreatic Cancer Research

"In 2008 Jefferson Kimmel Cancer Center studied the effect of Nigella sativa on pancreatic cancer tumor cells and discovered that they were able to kill 62% of the cells. Future research by Jefferson showed that with the use of Nigella sativa, they were able to annihilate or cause cell death on 82% of tumor cells. In addition to the positive results on pancreatic cancer, they found more results worth noting. According to Hwyda Arafat, M.D., Ph.D., associate professor of Surgery at Jefferson Medical College of Thomas Jefferson University, "Nigella sativa helps treat a broad array of diseases, including some immune and inflammatory disorders. Previous studies also have shown anticancer activity in prostate and colon cancers, as well as antioxidant and anti-inflammatory effects."

Luffa

Luffa Leaves are used to treat cancer as well: supposedly a large remedy in the Middle East
http://flaxindia.blogspot.kr/2013/04/luffa-leaves-used-to-treat-cancer-1.html

Ginger

Ginger Destroys Cancer More Effectively than Death-Linked Cancer Drugs
http://naturalsociety.com/ginger-destroys-cancer-more-effectively-than-cancer-drugs/#ixzz1ywNhos7h

Magnesium

Study: low magnesium levels—not Big Pharma money $pinners high cholesterol/fat—is leading predictor of heart disease

Tumeric

Science Confirms Turmeric As Effective As 14 Drugs
http://wakeup-world.com/2013/05/26/science-confirms-turmeric-as-effective-as-14-drugs/
26th May 2013
By Sayer Ji


Turmeric is one the most thoroughly researched plants in existence today. Its medicinal properties and components (primarily curcumin) have been the subject of over 5600 peer-reviewed and published biomedical studies. In fact, our five-year long research project on this sacred plant has revealed over 600 potential preventive and therapeutic applications, as well as 175 distinct beneficial physiological effects. This entire database of 1,585 ncbi-hyperlinked turmeric abstracts can be downloaded as a PDF at our Downloadable Turmeric Document page, and acquired either as a retail item or with 200 GMI-tokens, for those of you who are already are members and receive them automatically each month.
Given the sheer density of research performed on this remarkable spice, it is no wonder that a growing number of studies have concluded that it compares favorably to a variety of conventional medications, including:
  • Lipitor/Atorvastatin (cholesterol medication): A 2008 study published in the journal Drugs in R & D found that a standardized preparation of curcuminoids from Turmeric compared favorably to the drug atorvastatin (trade name Lipitor) on endothelial dysfunction, the underlying pathology of the blood vessels that drives atherosclerosis, in association with reductions in inflammation and oxidative stress in type 2 diabetic patients. [i] [For addition curcumin and 'high cholesterol' research – 8 abstracts] [Other studies now disagree that cholesterol has anything to do with heart disease: find any work by Mary Enig, or watch a summary of her biochemistry work by Sally Fallon of the Weston Price Foundation, a presentation entitled "The Oiling of America".]
  • Corticosteroids (steroid medications): A 1999 study published in the journal Phytotherapy Research found that the primary polyphenol in turmeric, the saffron colored pigment known as curcumin, compared favorably to steroids in the management of chronic anterior uveitis, an inflammatory eye disease.[ii] A 2008 study published in Critical Care Medicine found that curcumin compared favorably to the corticosteroid drug dexamethasone in the animal model as an alternative therapy for protecting lung transplantation-associated injury by down-regulating inflammatory genes.[iii] An earlier 2003 study published in Cancer Letters found the same drug also compared favorably to dexamethasone in a lung ischaemia-repurfusion injury model.[iv]  [for additional curcumin and inflammation research – 52 abstracts]
  • Prozac/Fluoxetine & Imipramine  (antidepressants): A 2011 study published in the journalActa Poloniae Pharmaceutica found that curcumin compared favorably to both drugs in reducing depressive behavior in an animal model.[v] [for additional curcumin and depression research – 5 abstracts]
  • Aspirin (blood thinner): A 1986 in vitro and ex vivo study published in the journalArzneimittelforschung found that curcumin has anti-platelet and prostacyclin modulating effects compared to aspirin, indicating it may have value in patients prone to vascular thrombosis and requiring anti-arthritis therapy.[vi]  [for additional curcumin and anti-platelet research]
  • Anti-inflammatory Drugs: A 2004 study published in the journal Oncogene found that curcumin (as well as resveratrol) were effective alternatives to the drugs aspirin, ibuprofen, sulindac, phenylbutazone, naproxen, indomethacin, diclofenac, dexamethasone, celecoxib, and tamoxifen in exerting anti-inflammatory and anti-proliferative activity against tumor cells.[vii] [for additional curcumin and anti-proliferative research – 15 abstracts]
  • Oxaliplatin (chemotherapy drug): A 2007 study published in the International Journal of Cancer found that curcumin compares favorably with oxaliplatin as an antiproliferative agenet in colorectal cell lines.[viii] [for additional curcumin and colorectal cancer research – 52 abstracts]
  • Metformin (diabetes drug): A 2009 study published in the journal Biochemitry and Biophysical Research Community explored how curcumin might be valuable in treating diabetes, finding that it activates AMPK (which increases glucose uptake) and suppresses gluconeogenic gene expression  (which suppresses glucose production in the liver) in hepatoma cells. Interestingly, they found curcumin to be 500 times to 100,000 times (in the form known as tetrahydrocurcuminoids(THC)) more potent than metformin in activating AMPK and its downstream target acetyl-CoA carboxylase (ACC). [ix]
Another way in which turmeric and its components reveal their remarkable therapeutic properties is in research on drug resistant- and multi-drug resistant cancers.  We have two sections on our site dedicated to researching natural and integrative therapies on these topics, and while there are dozens of substances with demonstrable efficacy against these chemotherapy- and radiation-resistant cancers, curcumin tops both lists:
We have found no less than 54 studies indicating that curcumin can induce cell death or sensitize drug-resistant cancer cell lines to conventional treatment.[x]
We have identified 27 studies on curcumin’s ability to either induce cell death or sensitize multi-drug resistant cancer cell lines to conventional treatment.[xi]
Considering how strong a track record turmeric (curcumin) has, having been used as both food and medicine in a wide range of cultures, for thousands of years, a strong argument can be made for using curcumin as a drug alternative or adjuvant in cancer treatment.
Or, better yet, use certified organic (non-irradiated) turmeric in lower culinary doses on a daily basis so that heroic doses won’t be necessary later in life after a serious disease sets in.

Nourishing yourself, rather than self-medicating with ‘nutraceuticals,’ should be the goal of a healthy diet.

[learn more at Sayer Ji's new collaborative project EATomology]


123 comments:

Mark said...

Glocosamine, Arthritis,
Misery, & The 'Dog-Test'
By Alan Graham (with Alfred Lehmberg)
AlienView.net
7-28-2006

Many ill-informed MDs, much like NPR's Dr. Zorba Pasture for instance, claim that glucosamine (for Arthritis) has not been proven to work in the first place and that the success stories are largely anecdotal, in the second; successful resolutions of arthritic health issues due to the use of glucosamine are only the result of the "Placebo Effect." You know, like a headache going away as a result of a sugar pill. The rest of the Zorba tale in a moment.

Contrary to Dr. Zorbie and the evil Vioxx, Celebrex, Bear Aspirin cabal -- glucosamine has had over 300 studies and 20+ clinical trials! All of these trials report that glucosamine works great for most folks... works marginally well for a few, and doesn't seem to work at all, for a very small percentage.

I suspect those not experiencing any relief just didn't stick with it long enough, thus falling victim to the one characteristic that makes people impatiently abandon glucosamine for aspirin or something more dangerous. It's that damnable lack of immediate gratification.

Non Steroidal Anti Inflammatory Drugs (NSAIDS), like aspirin, work almost immediately (complementing our "immediate gratification society," remember) but they do NOTHING to actually fix the problem and in fact block that "Cox 2 Pathway" helping to repair the cartilage deformation causing the pain... that's why they call aspirin a 'Cox 2 Inhibitor'... folks!

So, to recap, aspirin relieves the pain, marginally, now... ...but while facilitating worse pain, later on, in the long run. Fact! On the other hand, glucosamine, usually takes at least 2 weeks to relieve the pain... and with some folks as long as a month! Dust now or diamonds later, folks?

You see, glucosamine is not an anti-inflammatory or a pain reliever, it is the raw material (...made less with age!) to REPAIR the damage... ...so in 2 or 3 weeks the pain goes away like *magic*, but without the toxic pain relievers.

Of course, due to that bothersome principle of relativity, 2 weeks is a long time with your joints in a carpenter's vise. But, come on... honored reader... ...wouldn't you rather... repair the damage! Then, painlessly and inexpensively, continue the joint maintenance with the same stuff that Mother-Nature uses? The preceding is of course preferable compared to just temporarily masking the pain now... for greater illness later... requiring more expensive pain relievers and drugs? Reader, it's in your hands.

The 100% accurate "Dog-Test":

OK, forget about the 300 studies & 20 trials alluded to earlier... the "Dog Test" is fool-proof.

Several years ago I started back lifting weights after a long lay-off due to an injury. That's when I realized that my occasional, if burgeoning elbow twinge was arthritis. My joints became very swollen & inflamed every time I tried to work out. I took Aspirin for a while, but being a Holistic kind of guy, I started taking 1500mg of Glucosamine Sulfate (GS). Sure enough, within 2 weeks the pain just faded away... Hello!

This worked so well, as advertised, that I started giving 1000mg of GS daily to my 16 year old dog, so arthritic that it would take her about 90 seconds just to stand up & take her first step. Well you guessed it... in about 2 weeks she was able to get right up and take-off at a pretty good clip, for an old gal. She seemed grateful, too...

Well, being a self-styled scientist of some conscience, I felt I was obligated to conduct an experiment to insure it was the GS and not some sort of doggie remission. After a couple of months, with very little apparent stiffness, I quit giving her the GS. Sure enough, within 10 days she started showing the first signs of slowing down and was right back to her old "Stove-up" self in 3 weeks.

Yes, I started giving her the GS again, and just like before, she sprang back in about 2 weeks...and for the next 3 years, until she "laid down" for the last time, she could get up & down with youthful ease. Cut. Print! That's a wrap.

Your Doctor should be treating you as well, reader, as I treat my dog. You think?

Consider, because of the way we have "screwed around" with Mother-Nature by creating all of these drastically different doggie body-shapes, joint problems are more common in dogs than in humans... so it's easy to find an old arthritic dog if you want to do the "Dog-Test" yourself. If you adopted an elderly arthritic dog from the pound, say, before being euthanized, and then relieved her joint pain...I'm sure she would really appreciate it, love you until the end of her days, and protect you with her life.

Here is the 'coup de grace' to the Zorba anecdote alluded to earlier:

Dr. Z's radio show is live and because he has to respond to questions from callers, it is unrehearsed. Well, after he made the bogus "placebo" comment to a caller's query reference GS alluded earlier, Zorba's "side-kick", Tom, reported that he took GS for his arthritis and that it worked great!

Zorba then pontificated it was likely that "placebo effect" we've talked about...Then, out of the blue, Tom (inadvertently I'm sure), cut Zorba's legs right out from under him! Tom reported that his old dog could no longer climb the stairs and that after taking Glucosamine... the dog could run up the stairs!

I'm sure I don't have to point out the obvious... but, I will. Dogs really don't appreciate the subtleties of the "Placebo Effect," reader. With dogs it's "pure vanilla"... they are, what they are. They don't do psychosomatic, eh?

Good Vet - Bad Vet...on second thought, they're probably all bad. (I'm talking mainstream Veterinarian medicine, not Holistic Vets). Sorry in advance to all the Vet lovers, folks, I'm just judging a tree by its fruit.

Did you know that in Mainstream (Non-holistic) Veterinary Medicine there are two completely opposing philosophical views toward animal care? Both approaches are designed for maximum profit (sound familiar?) ...pretty much at the exclusion of everything else.

Vets who look after large commercial livestock will use nutrition & supplements to prevent disease because that's how the industry makes the most money, by having big, healthy livestock complete with all the nutritional building blocks. As a result, many diseases in farm animals are prevented, out of hand, by taking vitamins, minerals, trace minerals & EFA's (Essential Fatty Acids). Those very same diseases in humans, unfortunately are "managed" by toxic pharmaceuticals treating symptoms only, and doing nothing to fix or prevent the disease...

WHY? You already know the answer. That is where the most money can be made.

Now to the other philosophy. In contrast, Vets who look after your pets... have a different attitude... the same attitude, not so astonishingly, as MD's who look after humans, actually! Maximum profit drives that train remember. Mainstream medicine makes us sick ... keeps us sick ... while giving only the appearance that something positive is being done! Treating symptoms, merely, yet preventing or curing NOTHING.

Unlike big farm animals that have to be sold for profit... if you & *Fluffy* get sick and waste away, who cares? In fact, the soullessly psychopathic multinationals are counting on it. Humans & pets don't generate revenue if you prevent their disease, reader... can you see? They generate revenue by being sick & staying sick, while the medical community manages their disease.

Don't misunderstand me. Large animal Vets will not hesitate to feed animals unhealthful stuff as long as it makes them fatter for increased profit... for example, cattle feed high in meat protein (cows don't eat meat!) or polyunsat vegetable oils (all that Corn, in "Corn-Fed" Beef) suppressing the thyroid, causing weight gain... just like in humans! It sickens me, and should you... ...and in fact, DOES!

Ironically, the use of Poly-food oil in both livestock & humans, to gain weight, is the desired effect in both cases -- FAT livestock generate more profit when sold for meat and FAT humans generate more profit when kept sick & on expensive, toxic drugs for the rest of their increasingly miserable lives...

The following conversation with my dog's Vet illustrates how "Pet Vets" & Human MDs operate the same way.

Me -- "What is the first thing you recommend for arthritis, Doc"?
Vet -- "That would be our Doggie Aspirin, Mr. Graham."
Me -- "What's the second thing you recommend"?
Vet -- "Our finest Doggie Celebrex , Sir!"
Me -- "What's next?"
Vet -- " Well, Mr. Graham, that usually does the trick."
Me -- "Doc, instead of just masking the pain, why don't you try to repair the damage with Glucosamine?"
Vet -- "...Ah, well Mr.Graham, as it happens, we actually have Doggie glucosamine available."
Me -- "Oh really? Well Doc, why didn't you recommend Glucosamine... FIRST?"
Vet -- " ...Ah, well...hum-muna, hum-muna... Ah, yeah, I guess from now on I could do that... and will that be cash or charge"? ...Of course I was giving him the old "Maybe I'll twist your nose off your sweating face" glare!

So there you have it folks...it's all about profit and has virtually nothing to do with prevention & cure...well, unless you're an expensive commercial milk-cow...then you will be covetously fed every nutrient, vitamin, mineral, trace mineral & EFA for optimum health & disease prevention, as is profitably available. See how that works?

Lastly, there are numerous supplements helping to alleviate joint pain, but in deference to the late "Great" James Coburn, (he was the tall, quiet knife-thrower in "The Magnificent Seven"), I would like to recommend a natural form of Sulfur...

MSM ( Methyl-Sulfonyl-Methane ). You may be allergic to Sulfa - but it is impossible to be allergic to Sulfur.

Mr. Coburn had arthritis in his fingers so cripplingly bad that his ruined hands had that terrible "bird-claw" look to them. Because MSM actually relieved his terrific pain, he gave permission to use his likeness & testimony for promotion of MSM... ...even after his death! I'd say that's a solid for MSM, eh?

Here is an excerpt from his CNN Obit -- "...He told The Associated Press in a 1999 interview he "healed himself" of the arthritis with pills having a sulfur base. His knuckles remained gnarled, but he said that the pain was gone." There it is. Be smarter than your doctor. Be treated as well as a cow.

...And thank you, Mr. Coburn... until next time, Sir, and I see you on the other side...

...Those of us still this side? Well be!

Alan D. Graham
(334) 774-0395
alan068@centurytel.net

Mark said...

The Vibe Machine, by Gene Koonce

VIBE Machine Interview With Gene Koonce

Interview with the inventor of the VIBE Machine in Greeley, Colorado.

Views: 14,244
Added: 1 year ago
Time: 18:33

http://www.youtube.com/watch?v=XBcPAyo9kdg

FREQUENTLY ASKED QUESTIONS

What does the VIBE Machine do?

The VIBE machine is an electronic device that brings the vibrational level of your body back to its natural state of being. VIBE stands for Vibrational Integrated Bio-photonic Energizer.

Can the VIBE be used by anyone?

Clinical data is not complete at this time, so we cannot allow individuals who have pacemakers or other devices which contain microprocessors or electronic pumps or pregnant women to sit in front of the VIBE Machine.

I saw a cheaper machine similar to the VIBE on another site, why should I buy from VIBE Technologies?

The Original VIBE Machine was designed by Gene Koonce who has an extensive background in electronics. Other devices that attempt to generate the effects of the Original VIBE Machine are untested and DO NOT produce the same results, nor do they have the hundreds of testimonials that indicate their effectiveness. Many of these could actually make conditions worse. If you have any questions call Gene Koonce at 970-356-9594 to find out why these imitations can be so dangerous to use.

Do I have to get hooked up to it with wires?

No. You simply sit approximately 3 feet from the device and the bio-photonic energy pours through you. There are no wires or devices you come into contact with. The frequencies are sent through every living organism within the range of the machine. To demonstrate that the energy is going through your body, you can even illuminate a fluorescent light bulb held behind your back.


How many times a day should I sit in front of my VIBE Machine?

The VIBE machine has been beneficial to individuals who sit in front of it for 30 seconds to 4 minutes, one time per day.

Are there any side effects from using the V.I.B.E?

A true VIBE Machine will have no side effects, but may create a Healing Crisis, otherwise known as a Herxheimer reaction. This will manifest itself as flu-like symptoms for 4-12 hours after a VIBE session. We believe that this is a result of toxins being flushed from the body. We have been told that increasing water intake helps this to be a much gentler experience.

How can I personally experience a VIBE machine?

Use our Vibe Machine Locator, contact Gene at 970-356-9594 or email us at gene@vibemachine.com

Mark said...

New Research Links
Infection With Cancer
Study raises hopes antibiotics may be an
alternative to chemo, radiation
From Alan Cantwell M.D.
MSNBC.com
6-26-6

New research links infection with cancer Study raises hopes antibiotics may be an alternative to chemo, radiation The Associated Press Updated: 12:41 a.m. AKT Oct 31, 2005 PARIS - New research suggests that infection with bacteria from the Chlamydia family may play a role in the development of a type of lymphoma that affects the tissue around the eye, raising hopes that antibiotics may one day prove to be an alternative to chemotherapy or radiation.

The study, presented Monday at the European Cancer Conference, is the latest to link infection with cancer, following the establishment of the human papilloma virus as the major cause of cervical cancer and the bacteria Helicobacter pylori as a cause of stomach cancer.

"This is sensational," said Dr. Dieter Hossfeld, a professor of oncology at the University of Hamburg, Germany, who was not involved with the research. "It was first noted in Italy and now it's been confirmed on the other side of the world in Korea, and we've heard that there are similar findings in the United States, so it's not a regional disease and is obviously a valid thing," Hossfeld said.

The bacteria in question, Chlamydia psittaci, can be contracted from infected birds such as parrots. Scientists also suspect it can come from household cats because they also carry it. Chlamydia psittaci is known to cause a lung infection called psittacosis. In the study, Dr. Changhoon You from the Asan Medical Center in Seoul, South Korea, compared chlamydia infection in 33 people with ocular adnexal lymphoma, or OAL, and 21 people with a comparable but non-cancerous condition called non-neoplastic ocular adnexal disease. He found the Chlamydia psittaci strain was present in 78 percent of the cancer patients, but only in 23 percent of those in the comparison group.

In a previous study conducted in Italy, the bacteria were found in 80 percent of people with the lymphoma and in none of those in a comparison group of healthy people. "In the future, eradication of the (germ) could be a common treatment method for low-grade lymphoma, replacing current cytotoxic chemotherapy or radiation," You said. The Chlamydia family of bacteria has been linked to cancer before.

Scientists already have shown that another strain, Chlamydia trachomatis, is linked to the development of cervical cancer. Another, Chlamydia pneumoniae, has been linked to lung cancer. Ocular adnexal lymphoma belongs to a group of lymphomas where cellular changes result from immune system responses gone awry.

Scientists say it makes sense that infections such as chlamydia could contribute to the development of the disease. "It makes biological sense, but whether it will translate into anything practical, and for how many patients, this is the question," said Dr. Joachim Yahalom, a lymphoma specialist at Memorial SloanKettering Cancer Center in New York who was not connected with the research. In many of these types of lymphoma, an infection can start the process, but at some point the cancer becomes independent of the infection. So unless the infection is treated early, antibiotics may not be enough, Yahalom said.

Alan Cantwell M.D.
alancantwell@sbcglobal.net
http://www.ariesrisingpress.com

book:
FOUR WOMEN AGAINST CANCER
Bacteria, Cancer and the Origin of Life

Mark said...

cardiac glycosides can protect brain cells from death after stroke in laboratory models

newswire article announcements global 13.Jul.2006 07:24
health

Cardiac glycosides in prevention of ischemic stroke

author: Infarct Combat Project

Brazilian study confirm the findings of Duke University Medical Center researchers that cardiac glycosides provide neuroprotection in stroke occurrence. It was a study of 28 years that showed a low mortality for stroke in 1150 cardiac patients taking these drugs.

(ICP) -- Using a novel screening technology, Duke University Medical Center researchers have shown that drugs called cardiac glycosides can protect brain cells from death after stroke in laboratory models, and that the drugs are effective even if delivered six hours or more after the onset of stroke conditions (1).

"This discovery is exciting because it may lead to interventions to prevent or lessen the amount of brain damage suffered after stroke," said Donald C. Lo, Ph.D., director of the Center for Drug Discovery and associate professor of neurobiology at Duke, and primary investigator on the study.

Currently, only one drug has been approved by the Food and Drug Administration to treat stroke -- and it faces serious limitations, Lo said. Called recombinant tissue plasminogen activator, the drug must be given within a three-hour window after the onset of stroke. Also, because the drug is delivered intravenously and acts by breaking blood clots, it is ineffective against "hemorrhagic" strokes that happen when an artery bursts.

Lo speculates that cardiac glycosides may exert their beneficial effect during stroke in an analogous manner that in heart disease, by restoring calcium to healthy levels in brain cells and thereby preventing cell death. Calcium plays a key role in regulating normal cell function, and any changes in its cellular concentration -- such as those caused by stroke -- can be toxic (2).

Another recent study with statin drugs concluded that its use is associated with a reduced risk of stroke but not severity or mortality (3)

Related to the Duke University Medical Center research, a case study from Brazil confirm the very low mortality for stroke in 1150 patients with stable heart disease taking cardiac glycosides, during 28 years. The study was authored by Quintiliano H. de Mesquita and Claudio A. S. Baptista and published in Ars Cvrandi, a Brazilian medical journal in 2002 (4)

The stroke (ischemic + hemorrhagic) mortality in 28 years for the cardiac patients taking cardiac glycosides was:

- 994 patients w/out prior infarction - Stroke mortality: 13 cases (1.3%) = 0.04% per year.
- 156 patients with prior infarction - Stroke mortality: 7 cases (4.4%) = 0.15% per year.

For a better comparison in stroke mortality, with those taking cardiac glycosides, we can take the data from the HPS study, which had a follow-up of 5 years, involving 20.536 patients aged 40-80 years with coronary heart disease, other vascular diseases or diabetes. The HPS found a total stroke mortality of 0.9% (0.18% per year) in patients taking statins and 1.2% (0.24% per year) in patients taking placebo (5)

The permanent use of cardiac glycosides (Digitoxin, Digoxin, Acetildigoxin, Lanatoside-C, Betametildigoxin, or Proscillaridin-A) in low, daily therapeutic (non-toxic) doses from the Brazilian study was based on the Myogenic Theory of Myocardial Infarction and had as its objective the prevention of acute coronary syndromes (6, 7). The global mortality for the patients without previous myocardial infarction was 14.2% (0.5% per year), while the global mortality for the patients with previous myocardial infarction was 41.0% (1.4% per year). The numbers for mortality and morbidity are described in the Table 5 of the article. (1)

References

1. Cardiac glycosides provide neuroprotection agains ischemic stroke: Discovery by a brain slice-based compound screening platform, James K. T. Wang, Donald C. Lo et al, Proc Natl Acad Sci U S A. 2006 Jun 22; Full and free text at link to www.pubmedcentral.gov
2. Study Spots Potential Stroke Drugs, http://www.dukemednews.org/news/article.php?id=9754
3. Statin use and sex-specific stroke outcomes in patients with vascular disease, Cheryl D. Bushnell et al, Stroke, 2006; 37:1427
4. Cardiotonico: Insuperavel na Preservacao da Estabilidade Miocardica como Preventivo das Sindromes Coronarias Agudas e Responsavel pela Prolongada Sobrevida--Casuistica de 28 anos (1972-2000), Mesquita, QHde e Baptista, CAS. Ars Cvrandi. May 2005, Volume 35, republished in 2005 at link to www.infarctcombat.org.
5. The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomized placebo-controlled trial, Heart Protection Study Collaborative Group. BMC Medicine 2005, 3:6 -- http://www.biomedcentral.com/1741-7015/3/6
6. Myogenic Theory of Myocardial Infarction Book with summary in English at http://www.infarctcombat.org/LivroTM/parte8.htm.
7. Some articles in English about the Myogenic Theory are available at: http://www.infarctcombat.org/MyogenicTheory.html.

homepage: homepage: http://www.infarctcombat.org

add a comment on this article
post-stroke recovery often improves with acupuncture therapy 13.Jul.2006 15:49
acupuncturist link

Thanks for posting this information!

I just want to add a little more information about one therapy that can be considered after a stroke has already happened; There are many studies that show that when stroke patients are treated with acupuncture therapy by trained acupuncturists, these patients often experience improvement in their post-stroke symptoms. In China many people who suffer strokes are treated with acupuncture therapy immediately after they have stabilized, because it is known that results are better when immediate treatment is given. After around 6 months have lapsed, there is less dramatic improvement, but some good results often still occur with treatment 12-18 months post-stroke.

Here are some studies:

link to stroke.ahajournals.org
http://stroke.ahajournals.org/cgi/content/abstract/32/3/707?ijkey=784328dd98fbbfb2e274d3751a6ed6d7f437fb06&keytype2=tf_ipsecsha

link to jama.ama-assn.org
http://jama.ama-assn.org/cgi/content/abstract/280/17/1518?ijkey=75c3a0a68878a5c5810b14b572d6fb5244abf89b&keytype2=tf_ipsecsha
http://www.yinyanghouse.com/chinesetheory/treatments/treatment-stroke.html

and here's a little background information explaining how stroke is looked at from an oriental medicine perspective:
link to www.yinyanghouse.com

Mark said...

Digitalis, a heart drug, also is an anticancer agent with properties of inducing apoptosis and inhibiting proliferation of cancer cells

newswire article reporting global 19.Apr.2006 06:58
health
Digitalis: The Insulin for Cancer?
author: Infarct Combat project
Digitalis, a heart drug, also is an anticancer agent with properties of inducing apoptosis and inhibiting proliferation of cancer cells. This is confirmed by a new study that found very low cancer mortality in many cardiac patients taking digitalis.
ICP, April 17, 2006 --- Coronary heart disease is the prime motivation of the Infarct Combat Project (ICP). However, there are paramount cases in other medical conditions which ICP can't neglect its participation and contribution. The present news is related with the use of an effective and inexpensive heart drug, for the treatment of cancer.

In a paper published in 2002 at Ars Cvrandi, a Brazilian medical journal, it was perceived an exceptional low mortality by cancer in cardiac patients treated with digitalis or other cardiac glycosides, when used in prevention of cardiac failure, unstable angina, acute myocardial infarction and sudden death.

This case study involved 1150 patients with stable coronary heart disease. The follow-up period was 28 years. The cardiac glycosides employed were: Digitoxin, Digoxin, Acetyldigoxin, Betametyldigoxin, Proscillaridin-A or Lanatoside-C at daily therapeutic oral doses - non toxic, preferably lower.

It was shown in this study that the global mortality for the patients without previous myocardial infarction was 14.2% (0.5% per year) while the global mortality for the patients with previous myocardial infarction was 41.0% (1.4% per year). Surprisingly, the cancer mortality in these patients treated with digitalis or other cardiac glycosides was just 1.7% in total.

This curious information prompted ICP to verify the cancer mortality rate for patients in similar medical condition and age, presented in other studies. Also, it was made a search at Medline, founding many studies showing digitalis as anticancer drug, with properties of inducing apoptosis (cell death) and inhibiting proliferation of cancer cells.

For the cancer mortality comparison the data was taken from a large study which had a follow-up of 5 years, involving 20.536 patients aged 40-80 years with coronary heart disease, other vascular diseases or diabetes. The bench-mark study found a cancer mortality of 3.3% (0.7% per year), in patients taking statin or placebo (inactive substance), while the study using digitalis or other cardiac glycosides, found a much lower mortality rate for cancer (0.06% per year)..

Unfortunately, the astonishing finding of extremely low cancer mortality in the cardiac patients taking digitalis couldn't be explored in the study signed by Quintiliano de Mesquita and Claudio Baptista. Cancer was not its main focus and a control group for this purpose is lacking.

Studies pointing a reduction in mortality by cancer in patients taking digitalis are not new. In fact there are some writings stating that in the beginning of the past century the first study about this relationship was happened. Anyway, just in recent years the scientific confirmation came, suggesting digitalis as a potential anticancer agent.

Perhaps the actual lack of interest on using of digitalis and other cardiac glycosides, as anticancer agents, start to change from now on with the development in US of a new technique, called neoglycorandomization. This scientific approach allows the manipulation of these drugs composition in their molecular structure, enhancing its capacity to fight malignant cells. Certainly this new technique, permitting the creation of patentable formulas for the tweak digitalis, will generate huge interests by the pharmaceutical companies, deeply affecting the research of new drugs, with the "rediscovery" of digitalis to fight coronary heart disease and cancer.

It is remarkable that during the past few years many patents applications were filled in US, related to the use of some cardiac glycosides (digoxin, digitoxin, oleandrin, ouabain, etc) when indicated in the treatment of cancer including in conjunction with other methods like radiotherapy.

In addition, it was developed, very recently, an extraordinary hypothesis that seems to fit perfectly well in the idea of digitalis as the "insulin" for cancer. It postulates that alterations in the metabolism of endogenous digitalis-like compounds* and in their interactions with the Na/K-ATPase (Sodium/Potassium pump) may be associated with the development of cancer.

* Endogenous digitalis-like compounds of the cardenolide (digoxin and ouabain) and bufadienolide (Proscillaridin-A and Marinobufagenin) types have been recently isolated from human tissues and body fluids, showing similar molecular structure of cardiac glycosides extracted from plants.

__________________________________________________

Infarct Combat Project is an international non-profit organization that provides information, research and education to fight heart disease. The ICP homepage is http://www.infarctcombat.org

__________________________________________________


References:
1. Cardiotônico: Insuperável na Preservação da Estabilidade Miocárdica como Preventivo das Síndromes Coronárias Agudas e Responsável pela Prolongada Sobrevida -- Casuística de 28 anos (1972-2000), Mesquita, QHde e Baptista, CAS. Ars Cvrandi, Volume 35 - nº 3 - maio de 2002. Republished at Internet, 2005 -- link to www.infarctcombat.org
2. A New Explanation Strengthen an Old Remedy and Shed Light to the Coronary Heart Disease Enigma, ICPwire, April 5, 2006 at http://www.infarctcombat.org/media/040506.html
3. "Two Heart Disease Theories, Same Therapeutic Treatment", by Carlos Monteiro, ICP, with comments by Dr. Thomas Cowan, Fourfold Healing Newsletter of November/December/05 link to www.fourfoldhealing.com
4. Digitalis, cancer and cardiac patients, Letter from Carlos Monteiro, ICP. Townsend Letter for Doctors And Patients -- to be published soon -- http://www.townsendletter.com/
5. The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomized placebo-controlled trial, Heart Protection Study Collaborative Group. BMC Medicine 2005, 3:6 -- http://www.biomedcentral.com/1741-7015/3/6 (Table 2)
6. Cardiac glycosides and breast cancer revisited, Stenkvist B, N Engl J Med 1982 Feb 25;306(8):484
7. Digitalis and cancer, Goldin AG, Safa AR, Letter, Lancet 1984 Oct 13;2(8407):875
8. Is digitalis a therapy for breast carcinoma? Stenkvist B, Oncol Rep. 1999 May-Jun;6(3):493-6 -- http://tinyurl.com/7b9m9
9. Cardiac Glycosides vs Alkylating Agents in Medical Oncology, Letter from Johan Haux. Townsend Letter for Doctors and Patients, Oct 2000 -- http://www.cancerwire.com/HauxTLDPdec2000.pdf
10. Digitalis is the right drug being used to treat the wrong disease. Wayne Martin, Barry Groves, Second Opinions, 2000 -- http://www.second-opinions.co.uk/heart_drugs.html
11. Digitoxin in non-toxic concentrations, inhibits proliferation and induces cell death in Jurkat T cells in vitro, Haux et al. Z-Onkol, 1999, 31 (1):14-20
12. Digitoxin is a potential anticancer agent for several types of cancer, Haux J, Med Hypotheses 1999 Dec; 53(6):543-8 -- http://tinyurl.com/e2pkt
13. Digitoxin in non-toxic concentrations inhibits proliferation and induces cell death in prostate cell lines, Haux et al. Z-Onkol, 2000, 32 (1):11-16
14. Cardiac glycosides stimulate Ca2+ increases and apoptosis in androgen-independent, metastatic human prostate adenocarcinoma cells, McConkey DJ et al Cancer Res. 2000 Jul 15,60(14):3807-12 -- http://cancerres.aacrjournals.org/cgi/content/full/60/14/3807
15. Anticancer effect of digitoxin, Wayne Martin, Townsend Letter for Doctors And Patients, July 2003 -- http://www.townsendletter.com/July2003/LTRmartin0703.htm
16. Digitoxin medication and cancer; case control and internal dose-response studies, Johan Haux et al, BMC Cancer 2001, 1:11 http://www.biomedcentral.com/1471-2407/1/11
17. Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients, Miguel López-Lázaro et al, J. Nat. Prod, October 18, 2005 -- http://tinyurl.com/89862
18. Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization, Joseph M. Langenhan, Jon S. Thorson et al. Proc Natl Acad. Sci 2005 Aug, 16 -- http://www.pnas.org/cgi/content/abstract/0503270102v1
19. Enhancement of radiotherapy by an endogenous cardiac glycoside. U.S. Provisional Patent Application Ser. No. 60/508,936, filed on Oct. 2, 2003 and published at Freshpatents.com on 26/05/05 -- http://www.tinyurl.com/c6zqb
20. Digitalis induced signaling by Na+/K+-ATPase in human breast cancer cells, Kometiani P et al. Mol Pharmacol 2005 March; 67(3): 929-36 -- http://www.meduohio.edu/depts/pharm/pdf/929.pdf
21. Na/K-ATPase, endogenous digitalis like compounds and cancer development - a hypothesis, Weidemann H. Front Biosci 2005 Sep 1;10:2165-76 -- http://tinyurl.com/9tbbe
22. Sodium/potassium ATPase (Na(+), K(+) - ATPase) and ouabain/related cardiac glycosides: a new paradigm for development of anti-breast cancer drugs? Chen JQ, Contreras RG et al. Breast Cancer Res Treat 2005 Dec 2;1-15 -- http://tinyurl.com/d27lc
23. Wilhelm Schoner - Endogenous cardiac glycosides, a new class of steroid hormones, Eur J Biochem. 268, 2440-2448, 2002. http://content.febsjournal.org/cgi/content/full/269/10/2440
24. Digitalis: new actions for an old drug, Wasserstrom JA, Aistrup GL, Am J Physiol Heart Circ Physiol, 289: 1781-1793 http://tinyurl.com/m3cl8

http://www.infarctcombat.org

add a comment on this article


There's many safer options 20.Apr.2006 00:17
the dark herbal nurse link

There are many much safer herbs, noxious weeds even, that cause apoptosis and/or slow cell proliferation and/or many other anti-cancer properties. Digitalis is still a drug, though it comes from a plant and isn't very expensive, but there are numerous plants growing aroung you for free, full of antioxidants, and sometimes cancer fighting properties. When combined with exercise and other healthy habits, people are much less likely to get cancer. Lots of people get cancer cause they're real old and its time to go towards the light. Others are just unlucky genetically, and drugs is still a downhill battle for them.

People usually reap what they sow. relax. Let the herd thin, there are simply too many humans!


Remember, there's a reason they're called drugs. 20.Apr.2006 21:44
Another nurse, though not quite as cynical. link

I am always inclined to urge people in favor of letting the herd thin to start with themselves.

But back to digitalis. It is not uncommon for 'old' medicines to find new uses. Certainly that has been the case with aspirin.

Before people start popping digitalis like M&Ms, keep in mind that this is a potent drug that, at least in hospitals, is given with caution. Without the right hemodynamics - which means, among other things, that your heart is pumping okay and you have sufficient blood pressure - you could easily make yourself very sick. Digitoxin over-dosing is one of the most common forms of medication over-dosing in the U.S.

And how many of you are prepared to calculate the correct dosage?

So, when you start bothering your MD or NP or naturopath, recall that this is just one study, not well replicated and, as my somewhat cynical colleague pointed out, you're better off just getting some exercise and eating right.

Now if we could just remove all the toxic chemicals and nuclear power plants.

---
http://portland.indymedia.org/en/2006/04/337956.shtml

Mark said...

newswire article announcements global 19.Apr.2006 00:32
drug war | health

Intravenous Vitamin C Cancer Cure Story Censored by Corporate AND Alternative Media

author: fightbigpharma

Recent revelations show that intravenous vitamin C can achieve blood concentrations capable of killing cancer cells.

However this is not picked up by the media because pharmaceutical advertising is the primary source of income for television and newspapers.


Thursday, March 30, 2006

Vitamin C Cancer Story Ignored By News Press

Knowledge of Health Blog, March 30, 2006

Its two days since the Canadian Medical Association Journal reported on three cases of prolonged remission from cancer after intravenous vitamin C therapy. The report is being given the cold shoulder. Its not being covered by the New York Times, WebMD, CNN, FoxNews, USA Today, nor by ABC, CBS or NBC News. In fact, its odd that such an important report would be published in a more obscure medical journal. In April of 2004 the Annals of Internal Medicine reported that intravenous vitamin C can achieve blood concentrations capable of killing cancer cells. This report was also ignored by the news media. When this reporter contacted Quackwatchs Dr. Stephen Barrett, to inquire if QW would consider removal of Dr. Linus Paulings name from its health quackery list, Dr. Barrett said he had no intention of doing so despite the growing body of evidence that now vindicates Dr. Linus Paulings work. Copyright 2006 Bill Sardi, Knowledge of Health, Inc.

So many are frustrated. It is becoming clear, in regards to health information, that pharmaceutical manufacturers hold a grip over the public by controlling government agencies and the news media. An example is the recent report that intravenous vitamin C may cure cancer. That report was relegated to an obscure medical journal and went unreported by major news outlets (New York Times, USA Today, CNN, FoxNews, ABC, NBC, CBS, WebMD) which better than 75% of the public rely upon for up to date health information.

A recent report in the Columbia Journalism Review of the news medias complicity in drug marketing notes that noted medical journalists chose not to warn the American public of the potential dangers posed by Vioxx because pharmaceutical advertising is now a primary source of income for television and newspapers.

Article continued @:

link to www.knowledgeofhealth.com

homepage: homepage: http://www.myspace.com/fightbigpharma

add a comment on this article
Beware: the Pharmaceutical Complex ENSLAVES people 19.Apr.2006 12:46
inquiring-mind link

Thanks for the link to the insightful article. This is such a major part of the 'big-picture' if people could just 'wrap their minds around it' and realize what it's about. Fascism is exhibited in many ways. The Corporate Pharmaceutical Complex is a big factor in the realm of corporatist-fascism. Is it any wonder the corporate-media doesn't cover the 'cancer-cure' story? It's "all connected", and is all about "controlling the masses". $ Profit $ comes before LIFE.

P.S.- You have a great myspace-blog. People should check it out.

what does Pharma have to hide? 19.Apr.2006 22:57
AZT = death sentence for many link

What do the pharmaceutical corporations have to hide? Why would the info about Vitamin C be such a threat if the good folks at Big Pharma really want to help and heal people who are sick? Pharma corps wouldn't have any hidden agendas, now would they?

"AZT: A Medicine from Hell

Anthony Brink

arbrink@iafrica.com

The more ignorant, reckless and thoughtless a doctor is, the higher his reputation soars, even amongst powerful princes.

Desiderius Erasmus (c. 1466-1536), Dutch humanist.

Praise of Folly, ch. 33 (1509).

National Health Minister Nkosazana Zuma has been condemned by just about everyone recently for her heartless decision not to make a drug called AZT available at state expense to HIV-positive pregnant women. It reduces the risk, so it's said, of the transmission of HIV from mother to child. Politicians and journalists from left to right have joined moist-eyed, hand-wringing doctors pleading for the free provision of AZT to these women, their babies cruelly deprived and doomed to die, they say.

In all the fuss about the minister's decision on AZT, no-one seems to have stopped to ask, "So what the hell is this stuff anyway?"

In 1964, a chemist, Jerome Horwitz, synthesized a sophisticated cell poison for the treatment for leukaemia*. He called it Compound S. Its formal title is 3'-Azido-3'-deoxythymidine, or Azidothymidine for short, but everyone knows it by its nickname, AZT.

It works like this. Thymidine is one of the four nucleotides (building blocks) of DNA, the basic molecule of life. AZT is an artificial fake, a dead ringer for thymidine. As a cell synthesizes new DNA while preparing to divide in order to spawn another, AZT either steals in to take the place of the real thing, or else disrupts the delicate process by interfering with the cell's regulation of the relative concentrations of nucleotide pools present during DNA synthesis. That's the end of the cell line. Cell division and replication, wrecked by the presence of the plastic imposter, comes to a halt. Chemotherapeutic drugs such as AZT are described as DNA chain terminators accordingly. Their effect is wholesale cell death of every type, particularly the rapidly dividing cells of the immune system and those lining our guts. Horwitz found that the sick immune cells went, but with so many others that his poison was plainly useless as a medicine. It was akin to napalm-bombing a school to kill some roof-rats. AZT was abandoned. It wasn't even patented. For two decades it collected dust forgotten - until the advent of the AIDS era.

In Europe and the US, HIV-positive 'long term survivors' quietly gather to form groups, having sloughed off the terror of the death sentences passed on them by their doctors. Here's the strangest thing. Without exception, what they find they all have in common is that they all eschewed (or quickly gave up) AZT, related nucleoside analogues like 3TC, and protease inhibitors. Some have pondered the unthinkable: that nearly all medically managed AIDS cases, always terminal, represent that balefully familiar phenomenon in the history of medicine, iatrogenicide - to be killed by the cure. Their reasoning looks less obscure when one reads the AZT package insert. To do so might tempt one to wonder impertinently whether AZT wasn't AIDS by prescription. Indeed, such perverse conjecture is actually confirmed in capitals: AZT use "MAY BE ASSOCIATED WITH HEMATOLOGIC TOXICITY INCLUDING GRANULOCYTOPENIA AND SEVERE ANEMIA" (destruction of white and red blood cells respectively), and "PROLONGED USE OF RETROVIR HAS BEEN ASSOCIATED WITH SYMPTOMATIC MYOPATHY (gross atrophy of muscle tissue) SIMILAR TO THAT PRODUCED BY HUMAN IMMUNODEFICIENCY VIRUS". As to the latter alibi, history will judge whether the thousands of healthy HIV-positive people who embarked on their metabolic poison treatment and wasted away (as the AZT insert predicted) would have died had they ignored doctor's orders and thrown their pills away. Here the syphilis story is instructive.

Before the introduction of mercury and arsenic salts as a treatment for this clap, the organic brain damage and dementia that signaled 'tertiary-' or 'neuro-syphilis' was quite unknown to medicine, and then disappeared when penicillin replaced the older decoctions. The moral is hard to miss. "

article continues @;

http://www.aidsinfobbs.org/debate.html

What are some recent findings about the effects of nutrition on the human immune system. Let's see what Dr. Rath has to say;

"On September 12, 2005 the world?s leading research institution, the US National Institutes of Health (NIH) finally had to admit that the decades-long promotion of cancer chemotherapy by the pharmaceutical industry was all part of an organized fraud. The NIH announced to the world: "Vitamin C can kill selectively cancer cells" - without any side effects. The publication of this study by this renowned research institution was no coincidence. It happened under scientific pressure from cancer research at the Dr. Rath Research Institute, one of the world's leading research institutes in natural health. Dr. Rath's research team, under the leadership of Dr. Aleksandra Niedzwiecki, had already published close to two dozen studies in leading scientific journals - all of them confirming that vitamins and micronutrients effectively block the spread of cancer cells. The fact that vitamins are the answer to the cancer epidemic will inevitably destroy the hundred billion dollar market for toxic and deadly 'chemo' drugs built up over decades by pharmaceutical multinationals.

After the breakthroughs in heart disease, cancer was the second major disease where scientific progress in vitamin research and natural health science has claimed victory against the fraudulent pharmaceutical business with ineffective, expensive and highly toxic pharmaceutical drugs. Now, the AIDS epidemic will be the next victory!

AFRICA HAS BECOME THE DUMPING GROUND FOR TOXIC AIDS DRUGS

Realizing that they are about to lose their multibillion dollar investments in cancer and heart disease drugs the pharmaceutical 'business with disease' has turned its attention to the AIDS market and the developing world.

The drug manufacturers and their agents have banked on South Africa and the rest of the continent being largely ignorant about the fraudulent nature of the pharmaceutical business. Over the past decades the pharmaceutical multinationals - the drug cartel - has turned South Africa and the entire African continent into a dumping ground for their toxic ARV drugs. AZT and other ARV drugs are 'chemo' drugs that are being used on AIDS victims because the 'chemo' market with cancer is about to collapse globally.

Some of these ARVs, like Boehringer's Viramune (nevirapine) have proven to be so toxic that they harm and kill people and are not allowed to be given to mothers nd their babies in other countries - not even in Boehringer's home country Germany.The people of Africa truly have been abused by the drug multinationals as experimental 'guinea pigs'. But this time is over now!"

article continues @;

http://www4.dr-rath-foundation.org/THE_FOUNDATION/youcan2005dec/02.html

Of course Dr. Rath has fallen victim to character assassination, with the website "quackwatch" calling him, of all things, a "quack." Never mind Dr. Rath also advocates an end to nuclear weapons stockpiling by ALL nations (including US!). Guess he believes that nuclear war would somehow be bad for people. My goodness, is Dr. Rath a hippie quack freak or what! What's the world coming to?

For the sake of entertainment, here's the site where Stephen Barrett, MD (guess nobody callin' him a quack, eh?) accusses Dr. Rath of being a "quack";

http://www.quackwatch.org/11Ind/rath.html

Barrett states;
"The Swiss Study Group for Complementary and Alternative Methods in Cancer (SKAK) and the Swiss Cancer League (SCL) is warning against the theories and products of Matthias Rath, M.D."

Guess there's no way either of these formidable sounding groups recieve even a single PENNY from the Pharma cartel, eh?

Barrett states;
"In 2005, the Advertising Standards Authority of South Africa ordered the Dr. Rath Foundation Africa to stop advertising that dietary supplements are safer and more effective than chemotherapy against HIV infections. The challenged ad, published in the November 26, 2004 Mail & Guardian, was headlined "Why should South Africans continue to be poisoned with AZT? THERE'S A NATURAL ANSWER TO AIDS." The objectionable claims included:

AZT has been found to cause children in utero to develop brain damage, neurological disorders, dparalysis, mental retardation, epilepsy, other serious diseases, and early death.

Daily doses of multivitamins slow down HIV disease and cut the risk of developing AIDS in half.

Non-patentable natural therapies have very low profit margins.

Every textbook of biochemistry recoignizes that vitamins and other micronutrients are the most decisive factor determining optimum function of the immune system [5]."

Dr. Stephen Barrett, are you telling people that these claims above are all false? Are you calling Dr. Rath a liar? You are being reminded that your credibility as a physician is subject to scrutiny also..

---
http://portland.indymedia.org/en/2006/04/337947.shtml

Mark said...

Electro frequency tech, Drug-Free Procedure Can Control, Reverse Diabetes

EFT: Drug-Free Procedure
Can Control, Reverse Diabetes
5-22-2006

SAN FRANCISCO, CA (PRWEB) -- A diabetes epidemic is overtaking the United States and the rest of the world. In less than 20 years, governments and social security systems may go broke paying expenses generated by this preventable illness. Diabetes cases are expected to double before the year 2025, and their health care costs will increase from $163 billion per year to $396 billion or more.

But while hospitals and public health services gear up for what they describe as an inevitable catastrophe, a small but growing number of diabetes patients are learning how to lose weight, balance their blood sugar, reduce their bodies' need for insulin, and heal complications such as leg ulcers and insufficient circulation in the toes and feet. They are doing this not by going on rigorous diets or exercise programs but rather by tapping with their fingertips on key acupuncture points while focusing on symptoms or emotional issues.

"EFT is bioenergetic medicine," explains best-selling health author Joseph Mercola, D.O. "It's based on the same energy meridians used in traditional acupuncture to treat physical and emotional ailments for over five thousand years, but without the invasiveness of needles. This combination of tapping the energy meridians and voicing positive affirmations works to clear the 'short-circuits' ­ the emotional blocks ­ from the body's bioenergy system, thus restoring the balance that is essential for optimal health and the healing of physical disease. More than any traditional or alternative method I have used or researched, EFT works."

Los Angeles physician Eric Robins, MD, agrees. "Some day the medical profession will wake up and realize that unresolved emotional issues are the main cause of 85 percent of all illnesses, including diabetes," he says. "When they do, EFT will be one of their primary healing tools, as it already is for me."

In one of many reports posted at the EFT website, Michael, a 59-year-old obese male, suffered from advanced type 2 diabetes, leg ulcers, and leg and back pain. After he learned EFT, which takes just a few minutes, his insulin requirement dropped from three injections per day to one per week, his blood sugar level dropped from 400 to 109, his leg ulcers began to heal, the blood pressure and circulation in his feet increased, his leg and back pain disappeared, and his energy level increased dramatically.

"Michael's results may sound unusual," says Gary Craig, the Stanford-trained engineer who developed EFT, "but in fact, his results are what EFT practitioners have come to expect. As soon as you remove energy blocks, the body often repairs itself without the use of prescription drugs or anything else. EFT is truly a universal healing tool and many physicians are adopting it."

Over 225,000 have downloaded Craig's free training manual and another 10,000 download it each month. The official EFT Manual has been translated by volunteer practitioners into nine languages.

The EFT Manual explains the basics so that anyone can begin applying EFT right away. It can be freely downloaded at:

http://www.emofree.com/downloadeftmanual.asp

Mark said...

[and nanoparticles KILL EVERYTHING ANYWAY, so it's hardly surprising. Nano should be highly regulated where it goes, and possibly entirely banned. It's the same principle as banning small scale soot particles that directly go into the brain or lung blood stream. Humans aren't built to stand such small particles and they are very biologically dangerous. Anyway, interesting article.

Silver Kills ALL Viruses, Study Finds
FreeMarketNews.com
10-21-2005

In a groundbreaking study, the Journal of Nanotechnology has published a study that found silver nanoparticles kills HIV-1 and is likely to kill virtually any other virus. The study, which was conducted by the University of Texas and Mexico University, is the first medical study to ever explore the benefits of silver nanoparticles, according to Physorg.

During the study, researchers used three different methods of limiting the size of the silver nanoparticles by using capping agents. The capping agents were foamy carbon, poly (PVP), and bovine serum albumin (BSA). The particles ranged in size from 1 to 10 nanometers depending on the method of capping. After incubating the HIV-1 virus at 37 C, the silver particles killed 100% of the virus within 3 hours for all three methods. The scientists believe that the silver particles bonded through glycoprotein knobs on the virus with spacing of about 22 nanometers in length.

While further research is needed, researchers are optimistic that nanological silver may be the silver bullet to kill viruses. The researchers in the study said that they had already begin experiments using silver nanoparticles to kill what is known as the super bug (Methicillin resistant staphylococcus aureus). Already used as a topical antibiotic in the medical industry, silver may now come under consideration as an alternative to drugs when it comes to fighting previously untreatable viruses such as the Tamiflu resistant avian flu.

Free-Market News Network
http://www.freemarketnews.com/WorldNews.asp?nid=1401

Mark said...

Ultra-fast shocks scramble cells
Powerful electrical pulses might zap tumours.

16 March 2004

HELEN PEARSON

Nanopulses can make cells commit suicide.
SPL

Using very short, very powerful electric shocks, researchers are developing a way to jolt cancer cells into committing suicide, or healthy cells into healing wounds.

The technique involves blasting cells with nanopulses. These are high-power electrical bolts that last a few billionths of a second. They deliver millions of volts - enough to light up a city, but each burst lasts much less than the blink of an eye.

Longer shocks blow a cell apart, but researchers have found that the fleeting nanopulses leave the cell membrane unaffected while mixing up its insides. Now they are working out how to vary the timing and intensity of the shocks to make cells behave in specific ways.

In some of the latest work, Karl Schoenbach and Stephen Beebe of the Center for Bioelectrics in Norfolk, Virginia, have shown that the pulses can make blood platelets clump together in the first stages of clotting. This is something that might ultimately accelerate wound repair.

But there is plenty to be worked out before the human body is zapped with nanopulses. James Weaver, who studies electrical effects in cells at the Massachusetts Institute of Technology, Boston, says they are at an early stage: "There are maybe ten papers published showing that something dramatic is happening."

Cell shock

Biologists already treat cells with mild electric shocks in the laboratory, a technique called electroporation. These shocks make temporary punctures in cell membranes so that cells can be pumped full of experimental genes or proteins.

Schoenbach and his colleagues were the first to recognise that you could use high-power, brief shocks to manipulate cells in other ways. Working with electrical engineers in the late 1990s, they discovered that such pulses fry bacteria and sterilize contaminated water.

One of the most significant discoveries was that nanopulses make mammalian cells commit suicide, rather than blowing them up. This is a relatively gentle way of killing, because scavenger cells come and swallow the debris. By contrast, long electric shocks explode cells and liberate toxic molecules that cause inflammation and pain.

For this reason, researchers hope to use nanopulses to kill cancer cells while leaving healthy tissue intact. Schoenbach's team has already shown that the pulses can shrink mouse tumours by over 50%, and is working on catheters or non-invasive ways to deliver the shocks to the body.

Quite how nanopulses trigger cell suicide still leaves scientists scratching their heads. One idea is that the shock flips molecules in the cell membrane from the inside to the outside, which tells surrounding cells of their imminent death. "It says 'get rid of me,'" says Thomas Vernier, who is studying the technique at the University of Southern California, Los Angeles.

However they work, the nanopulses are prompting a flurry of ideas for their use. They might replace liposuction as a way to demolish unwanted flab, or blast away the fatty plaques that cause heart disease. "It is like asking what to do with a newborn baby," says Weaver. "Our speculations probably will not pick up the most important things."

Nature News Service / Macmillan Magazines Ltd 2004

Mark said...

microwave radiation as typhus and lice disinfestation in camps in WWII by Germans

German 'Microwave'
Technology To Combat
Typhus - High Frequency
Delousing Facilities
At Auschwitz
By Mark Weber
Institute for Historical Review IHR.org
7-24-2005

According to popular legend, Auschwitz was an extermination center organized to kill as many Jewish prisoners as possible with the greatest possible dispatch.

In fact, though, the authorities responsible for Germany's wartime concentration camp network carried out extensive measures at Auschwitz, and other camps, to save inmates' lives. (Even Elie Wiesel complained how all prisoners were forced to take three showers a day to keep them clean and in stable sanitary condition. -ed)

Though for decades widely-known among specialized historians, note 1 this remarkable story has been unknown to the wider public, and one extraordinary aspect of it has remained secret for decades.

In 1944, during the final year of the war in Europe, the Germans installed and operated state-of-the-art high frequency facilities at Auschwitz to kill disease-bearing lice and other pests. These expensive installations, installed in response to the high death rate wrought by disease, worked on the same principle as the familiar microwave appliances widely used today in households around the world. These Auschwitz facilities, designed to help save lives, proved to be very effective.

French researcher Jean-Claude Pressac briefly mentioned this remarkable disinfestation facility in his 1994 book about the crematories of Auschwitz. note 2

Also, French revisionist scholar Robert Faurisson, in an essay published in 1995, cited the testimony of former Auschwitz inmate Marc Klein, first published in 1946, about "short wave delousing" at Auschwitz. note 3

But the first qualified and detailed look at this subject appeared in two lengthy articles published in 1998 issues of the German-language revisionist quarterly, Vierteljahreshefte für freie Geschichtsforschung, edited by Germar Rudolf. These articles were based primarily on documents buried in the voluminous collection of wartime German records that were seized by Soviet forces in 1945. For more than half a century these important historical records lay forgotten in Moscow's central archives. (The present article is based in large part on information in these two Vierteljahreshefte articles.)note 4

Typhus Danger

Before dealing directly with the high frequency delousing facilities, it is important to understand the general problem of disease, especially typhus, during the war, and the measures taken by the German authorities -- particularly at Auschwitz -- to combat the deadly scourges.

Typhus or "spotted fever" (German: Fleckfieber) is transmitted from one diseased person to another by lice infected with a micro-organism (Rickettsia prowazeki). Epidemic typhus flourishes among people in crowded living quarters, including ships, prisons, camps and ghettos, where poor sanitary conditions and bad hygiene prevail.

During the First World War (1914-1918), and even more in the years immediately following, some 25-30 million people in Poland, Ukraine, Russia and the Baltic suffered from typhus, or about 20-23 percent of the total population, of whom several million perished. "At the close of World War I," the Encyclopaedia Britannica has noted, "the disease was prevalent in Poland, Russia and Rumania, where estimates of cases and deaths between 1919 and 1923 ran into millions. In World War II from these areas it spread again into western Europe and caused devastating epidemics among refugees and displaced persons, particularly in the German concentration camps." note 5 So terrible was the scourge in Poland, that the United States dispatched a US Army team to the country, where it carried out extensive efforts to combat typhus among the civilian population, 1919-1921. note 6

When war broke out in Europe in 1939, German medical and military leaders were mindful of the terrible impact of typhus during the earlier conflict, and acted accordingly. At the outset of the Second World War, the most advanced method used to kill typhus-carrying lice was "Zyklon B."



This was the trade name of a pest control agent manufactured from the 1920s to the 1950s by the Degesch company of Frankfurt am Main. "Zyklon" is hydrocyanic or "Prussic" acid (HCN) absorbed in a porous material such as gypsum or diatomaceous earth, which is kept in tightly sealed cans until it is deployed by trained personnel. HCN's boiling point is 26 degrees C (79 F).

This commercially available pesticide was widely used before, during and after the Second World War by private companies, governmental agencies and military forces throughout Europe. It was frequently used by the German armed forces, including the SS, to delouse clothing and other effects, and to kill insects and rodents in buildings.

It is commonly believed that SS men used Zyklon to kill millions of Jews in gas chambers at Auschwitz and other German camps. But, in fact, SS men used Zyklon to help prevent camp inmates' deaths. They deployed it in very large quantities at Auschwitz and other wartime concentration camps by fumigating barracks, by delousing clothing in special gas chambers, and so forth, to destroy disease-bearing vermin. note 7

Combatting Typhus at Auschwitz

In each German concentration camp, including Auschwitz, a "garrison physician" (Standortarzt) was responsible, together with the other medical personnel, for implementing, coordinating and supervising hygiene and sanitary measures.

At Auschwitz during this period, the "garrison physician," or chief medical officer, was SS Hauptsturmführer (captain) Dr. Eduard Wirths. By all accounts, including the surviving wartime documents, he was a dedicated, kindly, and good-natured man who capably and conscientiously carried out his demanding dutiesin the large camp. note 8

When typhus broke out in the Auschwitz camp for the first time in the summer of 1942, the German authorities there responded resolutely. In an effort to halt the disease, Commandant Rudolf Höss ordered a full-scale quarantine (vollständige Lagersperre) of the camp in July 1942.

SS men and their families were not allowed to leave the camp area. As the epidemic continued to spread, Höss ordered further measures, including delousing actions with Zyklon, a prohibition against SS men and their families eating uncooked fruits and vegetables, disinfections of living quarters, obligatory vaccinations, and further restrictions on movement. Special "louse inspection" units were organized, and those who failed to observe the anti-lice measures were punished. note 9

On July 22, 1942, an official in the central Berlin office responsible for concentration camp administration (WVHA) radioed Auschwitz: "I hereby give permission for a five ton truck to go from Auschwitz to Dessau and back, in order to pick up gas [Zyklon] for gassing of the camp, to fight the epidemic that has broken out." This was just one of several such deliveries. note 10

But these measures proved inadequate. Even as the camp's hospital blocks were overcrowded with typhus victims, the disease continued to claim many lives.

In early December 1942, SS camp physician Dr. Wirths spoke at a meeting that had been called to address the typhus crisis. Reflecting the seriousness of the occasion, the attendees included local and regional government officials, military officers, and important civilian figures. note 11

Wirths reported optimistically that three large disinfestation, shower and sauna facilities can be put into operation right now, specifically two facilities for the inmates and one for SS troop members. The capacity of these facilities is some 3,000 to 4,000 persons per 24 hours.

The central WVHA office in Berlin-Oranienburg, which was responsible for the SS concentration camp system, sent a secret directive on December 28, 1942, to every concentration camp, including Auschwitz and Majdanek (Lublin). After sharply criticizing the high death rate, it ordered that camp physicians must use all means at their disposal to significantly reduce the death rate in the various camps.... The camp doctors must supervise more often than in the past the nutrition of the prisoners and, in cooperation with the administration, submit improvement recommendations to the camp commandants.... The camp doctors are to see to it that the working conditions at the various labor places are improved as much as possible.

The directive concluded: "The Reichsführer SS [Himmler] has ordered that the death rate absolutely must be reduced." note 12

Richard Glücks, head of the SS agency that supervised the concentration camps, informed the various camp commandants in January 1943: "As I have already pointed out, every means must be used to lower the death rate in the camp." note 13

In a letter of February 25, 1943, to the central WVHA office in Berlin-Oranienburg, which was responsible for the SS concentration camp system, Dr. Wirths summed up the situation: note 14

"As already reported, after the typhus epidemic in the Auschwitz camp had practically been suppressed in November and December, there followed a new rise in typhus cases among the Auschwitz inmates as well as among troops, brought by the newly arriving transports from the East. In spite of the counter-measures that were immediately taken, a complete suppression of typhus cases has still not been achieved."

Accordingly, the SS camp physician reported that there would be a three-week quarantine of the Auschwitz camp complex, including the main camp and Birkenau. During this period, he continued, "two thorough delousing and disinfection operations" would be carried out to completely eradicate lice, and thus eliminate the danger of new outbreaks of typhus.

In an April 1943, communication to the camp commandant, Dr. Wirths expressed grave concern about the sewer system in Birkenau, and concluded with a warning that unless appropriate measures are taken, the "great danger of epidemics would be inevitable." note 15

On May 7, 1943, the Auschwitz chief physician had a discussion with Dr. Heinz Kammler, head of the engineering and construction bureau of the central camp administration office (WVHA), and others, about inmate facilities at Auschwitz. Dr. Wirths warned that: note 16 "... maintaining the prisoners' health for the major tasks does not seem certain, due to the poor toilet conditions, an inadequate sewer system, a lack of hospital barracks and separate latrines for the sick, and the lack of washing, bathing and disinfestation facilities."


In his report on the meeting, Dr. Wirths noted that his superiors agreed with his assessment:

"The Brigadeführer [SS general Kammler] acknowledges the foremost urgency of these matters, and promises to do everything possible to ensure rectification of the shortcomings. He is somewhat surprised, however, that on the one hand, he receives reports from the responsible medical personnel that give a very favorable account of the sanitary and hygienic conditions, and on the other he immediately afterwards receives exactly opposite reports. The director of the ZBL [Auschwitz central construction office] is instructed to present proposals by May 15, 1943, for rectifying all problems under discussion."

This commitment by a high-level SS officer is all the more remarkable considering the growing shortages facing the German leadership due to the worsening military situation, which made it ever more difficult to procure supplies, manpower and money to insure minimal hygiene and sanitary standards.

In keeping with this, camp chief physician Dr. Wirths, in a May 28, 1943, letter to the Auschwitz central construction office (ZBL), asked for six circulating air delousing facilities, to be installed as quickly as possible. (These were in fact ordered the next day.) This request, Dr. Wirths explained, was being made "especially for the delousing and the disinfestation of the sick prisoners and their clothing ..." note 17

Because typhus continued to plague the camp complex, even more rigorous measures were imposed in January 1944. Simultaneously, all inmates were subjected to baths and disinfection, all clothes and bedding were sent to disinfection chambers, and all barracks were treated with Zyklon. This unprecedented campaign worked, and thereafter only sporadic cases of typhus were reported. note 18

A Polish inmate-physician, Dr. Alfred Fiderkiewicz, confirmed after the war that the camp administration and the dedicated SS physicians imposed strenuous and sometimes even radical measures to combat typhus in Birkenau, including large-scale Zyklon delousing of barracks and all clothing, improved diets for sick-bay inmates, and action by a special team to combat lice. As a result, the typhus plague was finally brought under control in January 1944, although tuberculosis was never completely eradicated and continued to claim many lives. note 19

High Frequency Delousing Facilities

In 1936, German technicians had noticed that high frequency radio waves produced by a large transmitter tube used to broadcast the Olympic Games from Berlin that year incidentally killed all nearby insects. Spurred by this, the Siemens-Schuckertwerke (Siemens-Schuckert works), together with the Reich Biology Institute in Dahlem, conducted tests on pest eradication using the high-frequency field of an electron tube.

After the problem of pest extermination once again became pointedly relevant following the outbreak of war in 1939, the Siemens-Schuckert company worked on developing a practical high frequency or "shortwave" (Kurzwellen) disinfestation facility. Collaborating with the firm on this project was a related company, the Siemens-Reiniger works in Erlangen, which produced medical instruments.

When this new technology was demonstrated to civilian and military authorities, the SS saw its applicability for large camps and quickly ordered several of the new facilities. (In contrast, the regular German army ordered one such installation, which apparently was never completed or made operational.)

The new high frequency facility was produced in both a mobile and a stationary model. The mobile version was designed to fit on a truck trailer. Operating it required access to a 380 volt electrical outlet or to a portable electrical generator.

At the end of June 1943, Dr. Willing of the construction-engineering bureau of the central WVHA agency reported with satisfaction on the efficiency of the new facility: note 20

"... After a pass through the ultra-shortwave field, which takes eleven to twelve seconds, all vermin as well as bacteria, germs, brood and nits are killed, and, given non-stop operation, 13,000 to 15,000 pieces of clothing can be sterilized per day."

Auschwitz Installation and Operation

Although the first high frequency disinfestation facility was supposed to arrive at Auschwitz on May 15, 1943, actual delivery was delayed. In mid-June 1943 the Reich Ministry for Munitions and Armaments assigned top priority to the new high frequency facilities.

At a meeting on July 1, 1943, Dr. Wirths assured colleagues that the stationary high frequency delousing facility would be ready to begin operation at Auschwitz in about eight weeks, and that a mobile facility was to arrive at the camp within the next three weeks. Installation of the mobile high frequency disinfestation unit -- each step of which is thoroughly documented -- was carried out between July 16, 1943 (commission) and October 21, 1943 (last requisition of materials).

The "Osten III" model stationary high frequency disinfestation facility -- a modification of the "Osten II" mobile model -- was set up in 1944 at the Auschwitz I main camp, in a building (BW 160) that originally was to house 19 Zyklon delousing chambers. It finally went into operation on June 30, 1944, and on July 29, 1944, the director of the SS Hygiene Institute tested its bacteria-killing ability.

Greater Efficiency

Before being treated in the new high frequency facility, the louse-infested clothing was first dampened slightly with a water spray-gun. Then the clothing was bagged into bundles of 12x40 centimeters each and placed on conveyor belts that carried them through the high-frequency generator's capacitor field. Operating on the same principle as the modern microwave oven, the facility quickly killed all lice and other pests, as well as any typhus-bearing bacteria. The facility could treat 400 kilograms of clothing per hour.

Auschwitz's new high-frequency delousing facilities immediately proved to be far superior to all other delousing methods of the period, including the widely used method of hydrocyanic gassing with Zyklon B. Treatment of infected clothing with Zyklon required 70 to 75 minutes, and Topf delousing ovens required 60 to 80 minutes per treatment. Disinfestation in gassing autoclaves required a similarly lengthy amount of time. By contrast, the high frequency delousing facility required just seconds to treat infected clothing.

Furthermore, the new technique was much more thorough. It killed not only lice and their eggs (nits), but even the typhus micro-organisms. The new high frequency facility also took much less space, and was markedly less expensive. The cost of installing the "standard" disinfestation facilities in Auschwitz was 153,000 Reich marks, whereas the cost of installing the high frequency facilities there was 75,000 Reich marks or, according to another source, 98,000 Reich marks.

On August 10, 1944, the Auschwitz camp physician reported to the central WVHA office in Berlin-Oranienburg "on the effectiveness of the stationary shortwave delousing facility."note 21 After taking time to train the required personnel, wrote Dr. Wirths, full operation of the facility began on July 5, 1944. The new facility functioned promptly and reliably, and was in nearly daily use. However, it was not operating at peak efficiency, in part because of power outages.

On daily average, he continued, the new facility processed 1,441 sets of underwear and matching garments, and 449 wool or quilt blankets. In other words, he went on, every 32 working days the facility processed the clothing of 46,122 persons, including their underwear and bedding. Under ideal conditions (with no power outages, for example), Wirths stressed, the facility's performance would be three times greater. Tests carried out in Auschwitz by the SS Hygiene Institute, Wirths continued, showed that treatment in the facility of three minutes per sack of clothing -- that is, about 45 seconds for each individual item -- completely destroyed all traces of staphylococcus, typhus and diphtheria.

In November 1944, the Auschwitz central construction office (ZBL) reported that "at the present time there is a stationary high microwave delousing facility in concentration camp I [Auschwitz] and a mobile one in concentration camp II [Birkenau]."

The efficiency of these "high tech" Auschwitz facilities, designed to help save prisoners' lives, contrasts sharply with the absurdly primitive technology of the camp's alleged homicidal gas chambers, supposedly meant to kill prisoners. As Holocaust historian Jean-Claude Pressac has written, the (supposed) homicidal gassing procedure at Auschwitz-Birkenau crematory facilities IV and V, for example, was cumbersome, "irrational and ridiculous." note 22

Auschwitz was not the only German concentration camp to receive one of the new "high tech" delousing facilities. In the fall of 1944, a stationary high frequency facility similar to the one at Auschwitz was installed at the Mauthausen camp (near Linz). At that same time, a mobile high frequency delousing facility arrived at Gusen, a satellite camp of Mauthausen, in response to an outbreak of typhus there. Efforts were also made to install a similar stationary facility in the Dachau concentration camp (near Munich), but apparently it was never put into operation.

Development of high frequency facilities continued even as Soviet and American troops were advancing into Germany. A certificate issued by the Reich Ministry for Armaments and War Production on February 22, 1945 -- just eleven weeks before the end -- noted that although the Siemens-Schuckert works had been evacuated from Breslau (because of the Soviet advance), a new testing and production facility was to be set up in central Germany. The document also stressed that development and production of high frequency devices by Siemens-Schuckert had the highest national priority, and deserved all possible assistance from Party, military and civil authorities. note 23

Summary

Records documenting the Auschwitz high frequency delousing facilities are only a small portion of the mass of German wartime files -- 83,000 documents, according to one estimate -- that have been uncovered from Russian archives after decades of neglect.

It is highly significant that among this enormous collection of secret German records, not a single one provides any evidence of mass killing, or even refers to a German wartime policy or program of "extermination." To the contrary, many of these documents -- such as those cited in this article -- further demonstrate the seriousness of the efforts by high-level government and SS authorities to maintain the health of inmates by combatting disease in the camps.

Deployment of "microwave" delousing facilities was just one of many conscientious measures taken by the SS authorities to save inmates' lives. Confirming this is a report on the high frequency installations, written in September 1945 (four months after the end of the conflict), apparently by a Siemens technician named Bay. The report points out: note 24

"We regretted that these facilities could not be used for their original application purpose, namely for delousing military equipment for the front, because they seemed more urgently needed by the camp personnel who requested them, because cases of typhus were constantly being observed among the camp inmates."

The discovery of long-hidden records on Germany's wartime high frequency delousing facilities suggests that other significant documents of the period may still await discovery, and that further important historical revelations about Auschwitz and the "Holocaust" issue are quite likely.

The revealing documents cited in this article, and many others like them, are routinely suppressed by those who uphold what Jewish educator Rabbi Michael Goldberg (in his 1996 book, Why Should Jews Survive?) aptly calls "the Holocaust cult." It is noteworthy that such documents have been found and brought to light not by "mainstream" historians, but rather by skeptical dissident (revisionist) scholars -- an implicit indictment of the dereliction, if not corruption, of the historical "establishment."

Notes

1. For example, in his 1989 book, Auschwitz: Technique and Operation of the Gas Chambers, French anti-revisionist researcher Jean-Claude Pressac acknowledged the difficulty of reconciling actual German policies at Auschwitz with the camp's alleged function as an extermination facility. He wrote (p. 512):

"There is incompatibility in the creation of a health camp a few hundred yards from four Krematorien [crematory facilities] where, according to official history, people were exterminated on a large scale ... It is obvious that KGL [camp] Birkenau cannot have had at one and the same time two opposing functions: health care and extermination. The plan for building a large hospital section in BA III ["Mexiko" section of Birkenau] thus shows that the Krematorien [facilities] were built purely for incineration, without any homicidal gassings, because the SS wanted to 'maintain' its concentration camp labor force."

2. Jean-Claude Pressac, Die Krematorien von Auschwitz (Munich: Piper, 1994), pp. 105-106, 113. Also cited in: R. Faurisson, "Antwort an Jean-Claude Pressac," in Auschwitz: Nackte Fakten (Berchem, Belgium: VHO, 1995), p. 63.

3. Robert Faurisson, "Antwort an Jean-Claude Pressac," in Auschwitz: Nackte Fakten (Berchem, Belgium: VHO, 1995), p. 63. Source cited by Faurisson: Marc Klein, "Observations et réflexions sur les camps de concentration nazis," Etudes germaniques, Nr. 3, 1946, p. 18.

4. The present essay is based on two articles about short wave (high frequency) delousing facilities at Auschwitz published in 1998 issues of the Vierteljahreshefte für freie Geschichtsforschung (VffG), Castle Hill Publisher, P.O. Box 118, Hastings, E. Sussex TN34 3ZQ, England -- U.K. The first of these, "Kurzwellen-Entlausungsanlagen in Auschwitz," by Dr. Ing. Hans Jürgen Nowak, appeared in the June 1998 VffG (2. Jg, Heft 2), pp. 87-105. The second of these, "Die Kurzwellen-Entlausungsanlagen in Auschwitz, Teil 2," by Dipl. Ing. Hans Lamker, appeared in the December 1998 VffG (2. Jg, Heft 4), pp. 261-273. For more further information and complete source references, see the original articles. These articles can also be downloaded from the VHO web site: www.vho.org. For more about Rudolf and his VffG quarterly, see "Important New German-Language Revisionist Quarterly," in the May-June 1998 Journal, pp. 26-27.

5. "Typhus," Encyclopaedia Britannica (Chicago), 1957 edition, vol. 22, p. 648.

6. Alfred E. Cornebise, Typhus and Doughboys: The American Polish Typhus Relief Expedition, 1919-1921 (Univ. of Delaware Press, 1982). See also: Friedrich P. Berg, "Typhus and the Jews," The Journal of Historical Review, Winter 1988-89 (Vol. 8, No. 4), pp. 433-481.

7. J.-C. Pressac, Auschwitz: Technique and Operation of the Gas Chambers (New York: B. Klarsfeld, 1989), pp. 15-21.

8. See also the information about Dr. Wirths, especially chapter 18, in: Robert Jay Lifton, The Nazi Doctors (New York: Basic Books, 1986).

9. Essay by Danuta Czech in: K. Smolen, ed., From the History of KL Auschwitz (Oswiecim State Museum: 1979), Vol. 2, pp. 28-36, 96-97. See also: Danuta Czech, comp., Auschwitz Chronicle: 1939-1945 (London/New York: I.B. Tauris, 1990), p. 202.

10. Eugen Kogon, and others, Nazi Mass Murder (New Haven, Conn.: Yale Univ. Press, 1994), p. 160; E. Kogon, and others, Nationalsozialistische Massentötungen durch Giftgas (Frankfurt: S. Fischer, 1986), p. 223. Also quoted in J.-C. Pressac, Auschwitz (1989), p. 188. Note similar documents in Raul Hilberg, ed., Documents of Destruction (1971), pp. 220-221, and in J.-C. Pressac, Auschwitz (1989), pp. 188, 557.

11. Document, dated December 4, 1942, cited in Vierteljahreshefte für freie Geschichtsforschung (VffG), June 1998, pp. 91 and 105, n. 29. Source cited: Moscow central archives, document No. 502-1-332-117/119. Also cited in: Y. Gutman & M. Berenbaum, eds., Anatomy of the Auschwitz Death Camp (1994), p. 226.

12. A. de Cocatrix, Die Zahl der Opfer der nationalsozialistischen Verfolgung (Arolsen: International Tracing Service/ICRC, 1977), pp. 4-5; D. Czech, comp. Auschwitz Chronicle: 1939-1945 (1990), p. 291; Nuremberg document PS-2171, Annex 2. Nazi Conspiracy and Aggression (NC&A "red series," 1946-1948), Vol. 4, pp. 833-834. (This directive was quoted, as document E-168, at the main Nuremberg trial by SS defense attorney Dr. Horst Pelckmann on August 7, 1946: Trial of the Major War Criminals Before the International Military Tribunal (IMT "blue series"), Vol. 20, pp. 434-435. It was also cited by Pelckmann on August 26, 1946: IMT, vol. 21, p. 605.)

13. Nuremberg document NO-1523 (Trials of War Criminals Before the Nuernberg Military Tribunals [NMT "green series"], Vol. 5, pp. 372-373.)

14. Quoted by Carlo Mattogno in his essay, "Die 'Gasprüfer' von Auschwitz," Vierteljahreshefte für freie Geschichtsforschung (VHO, Belgium), March 1998 (2. Jg., Heft 1), p. 16 (and fn. 26). Source cited: Document 502-1-68, pp. 115-116, from the archives of the Center for the Custody of Historical Document Collection, Moscow.

15. Actually, the camp sewer system was, relatively speaking, an exemplary one for that period, and especially in that partof Europe.

16. Source cited (VffG, June 1998, pp. 92 and 105, n. 32): Moscow central archives document No. 502-1-332-219.

17. A facsimile of this document is in VffG, June 1998 (2. Jg, Heft 2), p. 91. Source cited (p. 103, n. 40, and, p. 105, n. 37): Moscow central archives document No. 502-1-332-28. French researcher Jean-Claude Pressac has written that in all there were 25 Zyklon disinfestation gas chambers at Auschwitz. J.-C. Pressac, Auschwitz: Technique and Operation of the Gas Chambers (1989), p. 550.

18. Essay by D. Czech in: K. Smolen, ed., From the History of KL Auschwitz (Oswiecim: 1979), Vol. 2, pp. 28-36, 96-97.

19. A. Fiderkiewicz, "Typhus and delousing in the men's camp in Birkenau," in: K. Smolen, ed., From the History of KL Auschwitz (1979), Vol. 2, pp. 237-256.

20. This was the same basic technology employed in a procedure for sterilizing foods that "utilizes microwave energy and steam," which was developed in 1996 by the Göttingen Institute for Agricultural Technology.

21. A facsimile of this document is in VffG, June 1998 (2. Jg, Heft 2), p. 95. Also, the text is quoted in part on pp. 96-97. Source cited (p. 103, n. 9, and, p. 15, n. 58): Moscow central archives document No. 502-1-19-90.

22. J.-C. Pressac, Auschwitz (1989), pp. 384, 386. Also quoted in a review by M. Weber of this book, in The Journal of Historical Review, Summer 1990, p. 235. Of the (supposed) homicidal gassing procedure at Auschwitz-Birkenau crematory facilities (Kremas) IV and V, Pressac writes:


"Although the operating sequence looks simple enough, it had become [?] irrational and ridiculous. It was irrational to have victims going from the central room to the gas chambers, [and] then being brought back, thus destroying the linear logic of the initial design. It was ridiculous to have an SS man in a gas mask balancing on his short ladder with a one kg can of Zyklon B in his left hand while he opened and then closed the 30 by 40 cm shutter through which he introduced the pellets with his right hand. This performance was to be repeated six times ... A few steps installed beneath each opening would have avoided all this performance."


23. A facsimile of this document is in VffG, June 1998 (2. Jg, Heft 2), p. 97.

24. VffG, December 1998 (2. Jg, Heft 4), pp. 269, 271.

About the author...

Mark Weber, director of the Institute for Historical Review, was born and raised in Portland, Oregon. He was educated at Portland State University, the University of Illinois (Chicago), the University of Munich, and Indiana University (Bloomington). He has been editor of The Journal for Historical Review since April 1992.

http://www.ihr.org/jhr/v18/v18n3p-4_Weber.html

Mark said...

Radium Weed
Kills Skin Cancers

From Brian McDermott
Australia
12-8-2005


On the goggle box last night, the "doctors" and "experts" have suddenly "discovered" that the juice from Radium Weed (common name) causes sun spots, Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC) to disappear, and drop off!

Our grandmothers taught us this over half-a-century ago, and it was well-known in the bush, where we grew up!

Suddenly, the "experts" are feverishly working with it "discovering" it! No doubt trying to find a way to patent it!

Reminds me of Dr. Bill Cham's Curaderm, which is an extract from Devil's apple, also known for over half-a-century by people in the bush, also effective for skin cancers.

Then, they will ­ some years from now, perhaps never ­ "discover" that Cansema causes melanoma to drop off!

(The "authorities" have prohibited the advertising of Cansema for cancer, threatening 5 years jail, and fines of tens of thousands of dollars!)

Next, they will be discovering the "amazing" benefits of eucalyptus oil, putting a few drops in hot water and breathing the fumes in, putting a few drops on half a teaspoon of sugar and taking a small bit of it at a time, and breathing in the fumes, and having an almost immediate affect on colds and 'flu, all the while trying to find a way to "lock it up" and patent that also. They can't, so they keep it quiet, selling their expensive, useless, patented concoctions.

Then of course, they will never find a way to patent the best and most efficient, - and cheapest - disinfectant, hydrogen peroxide, SO THEY KEEP IT QUIET!

They do not use it as a disinfectant at all in hospitals, to sterilise anything, preferring to use expensive, patented "disinfectants" put out of course by the international pharmaceutical corporations ­ and next to useless! This is why there is so much disease in hospitals. Nothing is sterile!

So in recent years particularly, if you want to contract a disease, go to hospital! Infection is almost guaranteed!

There is not a microbe on the planet - bacterium, virus, or pathogen - which will survive a strong (10-20%, higher if necessary ) mixture of hydrogen peroxide. NONE! This includes AIDS, etc.

It is the cheapest, and most effective disinfectant on the planet, bar none.

Moreover, it is also the safest. After quite a short period of time in the atmosphere, it literally breaks down and disappears, with absolutely no residue.

After all, hydrogen peroxide is simply water, with an extra molecule of oxygen attached to it! So simple! So effective!

We use it in Central Queensland Free State all the time!

The establishment won't use it, because it is so cheap, so effective, and cannot be patented!

http://www.ann.com.au/herbs/Monographs/euphp.htm

Mark said...

Stem Cell Treatment Cures Multiple Sclerosis Patient

Stem cell op helps woman to stand again

Jun 22 2006


A WOMAN confined to a wheelchair for the past five years has told of the miracle moment she stood up after revolutionary stem-cell treatment.

Julia Sandeman, who suffers from multiple sclerosis, paid £13,500 for the make-or-break operation in a Dutch clinic.

After the procedure she regained sensation in her limbs and is now able to balance upright in a therapy pool, sparking fresh hope she will one day walk again.

Julia, who lives in a carer-assisted home in Stanley Street, Caterham, said: "I had tears in my eyes the moment when I was holding up my own body weight for the first time in years.

"Not only do I have some sensation I now believe I might regain full use of my legs."


Story continues Continue story
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The 33-year-old, who was a talented dancer before being diagnosed with MS eight years ago, said she dreams of walking hand in hand alongside her five-year-old daughter Jenna.

She said: "It felt like climbing Mount Everest when I stood up. My dream is to one day walk along a beach with Jenna.

"I just hope the stem cells keep on doing their work."

Julia suffered blurred vision and a loss of sensation in her limbs as the disease began to take hold of her body and she was forced to use a wheelchair.

In desperation she resorted to having cells from the umbilical cords of new-born babies injected into acupuncture points in her body.

The radical treatment, which took place in February at a Rotterdam clinic, is untried in this country but has seen Julia achieve incredible results.

So far she has completed simple but farreaching goals such as lifting her foot several times in succession and steadying her trembling hands enough to send a text message.

This week her father Peter, 68, told the Mirror he is so happy with her progress he is prepared to sell beloved photographs of him with his late friend John Lennon to help fund it further.

He said: "Julia has made a heck of a lot of progress. "We're so pleased with her and hope that one day she'll walk again.

"I'm very encouraged. Just her regaining bladder control was worth the price of the treatment alone. This operation has given us hope where we had none before." Amazing results: Julia Sandeman with her father Peter

surreyonline.co.uk

Mark said...

[Ramyond Rife rises once more..]


A PROPOSED EXPERIMENTAL/THEORETICAL, NONINVASIVE, NONPHARMACEUTICAL, IN VIVO METHOD FOR RAPID NEUTRALIZATION OF HIV VIRUS IN HUMAN SUBJECTS.
Revision March 13, 1996. Copyright 1991/95 by Robert C. Beck, D.Sc.

In a remarkable and startling discovery at Albert Einstein College of Medicine, NYC in 1990, it was shown that a minute current (50 to 100 micro amperes) can alter outer protein layers of HIV virus in a petri dish so as to prevent its later attachment to receptor sites. (Science News, March 30, 1991, page 207.) [They never found an HIV virus..., though read on:]

It may also reverse Epstein-Barr (chronic fatigue syndrome), hepatitis, Lupus, cancer and many others. HIV-positive users of this enclosed information may expect a dramatic reduction of symptoms after about 45 days. This is reminiscent of a well proven cure for snakebite by application of electric current that instantly neutralizes the venom's toxicity. (Lancet, July 26, 1986 page 229.)

And there may be several other diseases as yet undiscovered or untested viruses neutralizable with this discovery; perhaps more surprisingly even the common cold.

This very simple and valid blood clearing treatment proved of great promise as a positive method for immobilizing known strains of HIV still present and contaminating some European and US blood bank reserve supplies.

It was further suggested that infected human HIV carriers could be cured by removing their blood, treating it electrically, and returning it by methods similar to dialysis, or by surgically implanting electrode arrays with miniature batteries sewn inside blood vessels as described in US patent # 5,188,738. Dr. S. Kaali, MD, projected that "years of testing will be in order before such an in vitro (blood removed for treatment) device can be made ready for widespread use" (Longevity, December 1992 page 14). This paper reveals an alternate "do-it-yourself" approach for electrifying/purifying blood with no dialysis, implants, or medical intervention.

In the writer's opinion both blood and lymph can be cleared in vivo (which means blood isn't removed or skin ever penetrated) simply, rapidly, and inexpensively with similar but noninvasive do-it-yourself techniques described herein. All are fully disclosed in this paper. Also included are proven schematics, parts lists, electrode construction and complete instructions. Electronic and controlled electroporation approaches may easily make vaccines, antibiotics (even if possible someday), pharmaceuticals, supplements, herbs and diet therapies, plus other proposed remedies obsolete, even if they worked and were universally available at no cost immediately.

In a public lecture (October 19, 1991) the writer proposed this theoretical do-it-yourself method for eliminating HIV, parasite, fungi, viral and pathogens in vivo. Subsequently his original modalities and protocols have been extensively peer reviewed, refined, simplified and made universally affordable (under $75 for both devices including batteries when self-made). These three simple treatments, used in tandem, can potentially nullity well over 95% (and perhaps 100%) of known electrosensitive pathogens residing in blood lymph. and other body tissue and fluids. Following is a summary of several years of testing with this non-iatrogenic, do-it-yourself, simple and inexpensive experimental solution to the ever escalating "incurables" dilemma. There are no known side effects since milliampere currents applied to skin are much lower than those in FDA approved TENS, CES and muscle stimulators which have been in safe daily use for many years. Battery replacement costs are about $1.32 per month per user or about $0.07 per day for a typical 21 day "spontaneous remission". No doctors, pharmaceuticals, shots, diets, medications or other intervention appears necessary.

One compact battery-powered blood clearing instrument is basically a miniature relay driven by a timer chip set to ~4 Hertz. Its 0 to 27 volt user adjustable biphasic output minimizes electrode site irritation. The described system delivers stimulation through normally circulating blood via electrodes placed at selected sites (such as one electrode below ankle bone on inside of foot and another on opposite foot) over the sural, popliteal, posterior tibial, or peroneal arteries where the subjects blood vessels are accessibly close to the surface (page 7) or on wrist or arm. Optimum electrode positions are reliably located by feeling for strongest pulse (page 5). Microcurrent treatment is of such low amplitude that it creates no discomfort when used as directed and is demonstrated to have no harmful side effects on healthy blood cells or tissue. A major obstacle to this simple, proven and obvious solution is disbelief. Treating approximately 120 minutes per day for four or six weeks should in the writer's opinion effectively neutralize well over 95% of HIV plus any other electrosensitive viruses, parasites, bacteria, pathogens, or fungi in blood. In heavy infections, shorter application times will prevent stressing patients with toxins. Simply treat for a greater number of days or ingest ozonized water. In time the restored immune system, plus silver colloid, may handle residual problems. In the special case of diabetically impaired circulation longer treatment times may be indicated. (See expanded instructions page 5). Immobilized viruses may be expelled naturally through kidneys and liver. More rapid neutralization is possible but not recommended because of potential excessive toxin elimination (Herxheimer's syndrome). T-cell counts usually drop initially because of lysing and scavenging by macrophages but should recover and increase after a few months. Even negative PCRs are sometimes reported.

Latent/germinating HIV reservoirs in body's lymph or other tissues and glands may theoretically be neutralized with a second and separate device by the strategy of generating a very high intensity (~10 kilogauss) short duration (~10 uS) magnetic pulse of > ~20 Joules by discharging a modified strobe light's capacitor through an applicator coil held against body locations over lymph nodes, thymus, kidneys, adenoids and other possible internal sites of latent infection (see page 8). By the physics of Eddy current/back EMF "transformer action" (Lenz law) the desired criteria of minimum current induced through infected tissue on the order of > 100 uA should be readily attained. Several pulses repeated at each site may insure a reliable "overkill" for successful disease neutralization. A magnetic "pulser" is very simple to build. Full instructions are on page 6.

But subjects must assume responsibility for their own health - a "heresy" in today's society conditioned to look for answers only to a medical establishment that has no current knowledge remotely promising "cures" for numerous other well known fatal diseases.

These "theoretical solutions" are being disclosed under constitutional freedom of speech guarantees in spite of extensively organized hostile opposition to non-pharmaceutical or inexpensive cures. Data can be legally offered only as theoretical and no medical claims can be made or implied. "See your health professional!" Anyone at his discretion and assumed responsibility should be free to build, use (on himself) and network his "research" results. With these data an average intelligent high school student should confidently be able to assemble both theoretical blood and tissue clearing modalities in about three hours and for a total investment of around $75.00. Components are widely available. After assembling "cures" cost about $1.50 per patient for batteries. If electronically unskilled, "busy" or technically illiterate, call an "Amateur Radio Supply" store (see yellow pages) and find a HAM radio operator, hobbyist or TV repairman or pay any kid on the block to do it for you. After "spontaneous remissions" some users may wish to interest their doctors. But be advised that electronic cures may be vigorously suppressed or ignored because there is presently no credibility nor drug cartel profit in this inexpensive AIDS solution. Also the 1910 Rockefeller-Flexner Report attempted to discredit electro-medicine with a conspiracy to inflate pharmaceutical profits.

I'm definitely not soliciting funds. This was independently developed by Bob Beck at his private expense and offered freely for "theoretical, informational and educational purposes only" and with absolutely no profit motive. Non-FDA approved devices are illegal to use within the USA except via little known FDA loopholes. Researchers are allowed to use anything on patients if safe, they build it themselves and don't sell them. (Code of Federal Regulations 21 chapter 807.65 subsections {d} & {f}. See actual text in footnote on page 4.) Although we will offer technical updates and always welcome feedback from users, please respect the writer's privacy and never attempt to contact him for additional help advice or information. Everything users need to know is included herein. We have nothing for sale.

2004 Extraordinary
Technology Conference
Salt Lake City, UT

Jul 29- Aug 1, 2004
Hosted by TeslaTech.info and the Institute of New Energy...
click here for more info

Bob Beck's Lecture Notes

Mark said...

[Paging Raymond Rife...]


Florida Man Invents Machine To Cure Cancer

POSTED: 11:49 am EST February 27, 2007
UPDATED: 10:20 am EST February 28, 2007
Email This Story | Print This Story

SANIBEL ISLAND, Fla. -- A Florida man with no medical training has invented a machine that he believes may lead to a cure for cancer.

John Kanzius, who turns 63 on March 1, is a former broadcast executive from Pennsylvania who wondered if his background in physics and radio could come in handy in treating the disease from which he suffers himself.

Inside his Sanibel Island garage, Kanzius invented a machine he believes sits on the brink of a major medical breakthrough.

The machine began to take shape four years ago, when his dreams of retirement were put on hold after he was diagnosed with a rare form of leukemia.

Kanzius' invention is not flashy, and it looks like a piece of 20th-century hardware. It doesn't even have a name.

"It's a kick-ass cancer cell generator," Kanzius called it.

After 24 rounds of chemotherapy, the former broadcaster decided that he did not want to see others suffer trying to cure the disease.

Kanzius said it was watching kids being treated that affected him the most.

"Particularly, young children walk in with smiles, and then you'd see them three weeks later and their smiles had disappeared. I said to myself, 'We're in a barbaric type of medicine,'" Kanzius told WPBF.

He began tinkering with pie plates and hot dogs, trying to use his broadcasting background to kill the cancerous cells.

Kanzius said his machine basically makes cells act like antennae to pick up a signal and self-destruct.

Unlike current cancer treatment, Kanzius' machine does not use radiation, and unlike today's radio-frequency treatments, it's noninvasive.

Now, some of the nation's most prominent doctors and scientists are using Kanzius' machines in their research.

In January, researchers said they performed a breakthrough at the M. D. Anderson Cancer Center in Houston.

"The complete killing of pancreatic cells in laboratory conditions is encouraging," Dr. Steve Curley said.

Curley is currently testing whether cancerous tumors can be wiped out in animals.

"We've got a lot more work to do, but this is very interesting preliminary work," Curley told WPBF.

Kanzius explained that his machine uses a solution filled with nanoparticles, which measure no more than one-billionth of a meter.

[this is similar to the tiny beads with nodules in vibratory zero point physics issues in the video "It Runs On Water"]

A test subject would be injected with either gold or carbon nanoparticles, which would make their way through the body and attach to the cancerous cells.

[Dangerous nanoparticles against human biology is not a good method.]

The test subject would then enter the machine and receive a dose of radio frequency waves, theoretically heating and killing the cancerous cells in moments and leaving nearby cells untouched.

"That is the holy grail -- when they attach, and research has shown that they're able to kill them once they attach to the cancer cells," Kanzius said.

[Er, surely they would attach to just about anything though...?]

Kanzius said he hopes to begin human testing with his machine within the next two years.

"The results look too phenomenal for anyone to stop at this point in time. I don't think the largest research center in the world would put time and effort and their name on a project if they did not think it would work," Kanzius told WPBF.

Kanzius told WPBF he does not want to try and build up false hope [because the technology if its cheap will be squashed by the medical corporate monopolists], but he mentioned that there could be some major announcements coming from researchers in the next coming months.

http://www.wpbf.com/health/

Mark said...

med How Honey Can Help Wounds Heal Better

How Honey Can Help Wounds Heal Better

POSTED BY
Dr. Mercola
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May 07, 2007
[Print this article]


Fifteen percent of diabetes sufferers develop ulcers, usually because of impaired sensation in their feet.

Every 30 seconds, someone in the world has their foot amputated as the result of a diabetic foot ulcer. In 2001, almost $11 billion was spent treating diabetic ulcers and amputations in the United States.

Researchers are currently conducting the first randomized, double-blind controlled trial investigating the use of honey for diabetic ulcers. Many experts believe that treating wounds with honey could offer tremendous benefits to the approximately 200 million diabetics worldwide.

Diabetics often have decreased ability to fight infection because of poor circulation, so diabetic ulcers treated with antibiotics can become colonized with drug-resistant organisms. But honey fights bacteria in numerous ways.

Honey's combination of acidic pH, low water content (which dehydrates bacteria), and the hydrogen peroxide secreted by its naturally-occurring enzymes make it effectively immune to resistance.
Science Blog May 3, 2007


Dr. Mercola's Comment:

If you thought that I was going to recommend that diabetics actually eat honey, even raw honey, you were wrong.

Please remember that if you are diabetic, overweight, have high blood pressure or high cholesterol, there is a strong likelihood that your insulin levels are too high, and raw honey may not be a good idea for you until you get those conditions under control.

The uses for honey -- already proven to have a natural antimicrobial effect against many bacteria and fungi -- are growing by leaps and bounds. The current research had its origins in the experience of a University of Wisconsin School of Medicine and Public Health professor and doctor, who successfully used honey to treat a borderline diabetic's open wounds.

The doctor prescribed topical honey after a strong staph infection the patient had been fighting for eight months continued to fester, despite the use of oral antibiotics. Once the honey treatment started, the wound healed completely within months, without the use of drugs, including antibiotics.

Honey can also help with diarrhea, insomnia, sunburn, and sore throats. But if you ingest honey as part of a treatment, rather than applying it topically, be sure to use raw honey. And even though it is one of the safest sweeteners to use, it still needs to be consumed in moderation, especially if you struggle with signs of insulin excess.

Should the healing properties of honey on diabetic ulcers hold up after closer scrutiny (and there's little doubt they won't), this could be a wonderful natural treatment for the patients around the world who deal with diabetes every day.

If only we can keep the honeybees from disappearing ...

If they do disappear, though, you can always use maggot therapy for wounds or one of my favorite wound dressings, Duoderm, which is particularly useful for burns. Duoderm really is amazing material; it nearly instantly relieves the pain from burns. I believe it works by restoring your body's damaged electrical system.

Related Articles:

Can Honey Help Fight Cancer?
http://www.mercola.com/2004/dec/22/honey_cancer.htm

Swiss Bee-Keepers Hold Key to MS Vaccine
http://www.mercola.com/2001/sep/5/bee_venom_ms.htm

The Wonderful Benefits of Bee Venom on RA
http://www.mercola.com/2004/nov/20/bee_venom_ra.htm

Mark said...

VIBE Machine Introduction

Few people have ever heard of Georges Lakhovsky (1869-1942) and his work with vibrational medicine, especially those who only speak English. A Russian engineer, he had emigrated to France before World War I. In 1929 he wrote a book, The Secret of Life. published in French. A few years later it was translated into Spanish, German, and Italian.. It was not until September, 1939, when Hitler attacked Poland and kicked off World War II, that it was finally published in English.

The book received almost no attention in the [allopathic already consolidated Rockefeller] English-speaking medical establishment.

Lakhovsky discovered that all living cells such as those in plants, animals, people, germs, and parasites, possess attributes of resistance, capacitance, and inductance which normally are associated with electronic circuits. Sustained by a small, steady supply of outside energy of the right frequency, these three electrical properties properly configured will cause the recurrent generation of high frequency sine waves, an effect known as “resonance.”

Resonance is easily recognized in the tiny energy inputs, properly timed, that allows you to push a child in a playground swing. As long as you push the swing a little, at the right moment (the correct 'frequency'), the motion will continue. If you push at the wrong time you damp the swing to another frequency. Electronics circuits which generate these recurrent sine waves can be called “electromagnetic resonators,” but are more commonly referred to as “oscillators.”

Georges Lakhovsky discovered that not only do all living cells produce and radiate oscillations of very high frequencies, but they also receive and respond to oscillations imposed upon them from outside sources. Outside source of vibratory oscillations originate from cosmic rays which bombard the earth continuously. This amazing realization during the golden years of radio not only led to a new method of healing by the application of high frequency waves, but broadened appreciation for the newly emerging field of science known as Radionics or Radiathesia.

When these outside sources of oscillations are in synchrony, exactly the same frequency as that produced by the cell, the strength and vigor of that cell will be reinforced and become stronger. If, on the other hand, these outside frequencies are slightly different, rather than reinforcing the cell's natural oscillations they might dampen or weaken them. As a resulting that cell loses vigor and vitality.

Cells of disease-causing organisms in a sick person produce different frequencies than those of normal, healthy cells. For people or plants suffering from disease Lakhovsky found that if he could increase the amplitude, but not the frequency, of the oscillations of healthy cells, this increase would damp the oscillations produced by the disease-causing cells thus kill the disease-causing cells trying to set up house-keeping in the body.

By increasing the amplitude of the natural frequencies

[

FAQ about the VIBE Machine
Articles about the VIBE Machine
About Gene Koonce
E-mail us about VIBE Machine


The VIBE machine helps raise your body's electrical vibration

The VIBE machine weighs approximately 85 lbs. When constructed the machine measures approximately 4' x 2' x 2'

Lasers inside 12 glass tubes stimulate noble, inert gases such as argon, and krypton to generate specific frequencies. These tubes are arranged in a specific pattern to create an electro-magnetic vortex to energize cells and tissues.

]

of disease-causing cells, their oscillations would gain strength and cause the person or plant to become weaker and more ill. Lakhovsky saw disease as essentially a battle between the vibratory frequencies of host cells and the vibratory frequencies of pathogens.

He tested his hypothesis using geranium plants. In December, 1924, he inoculated 10 plants with a plant cancer. After 30 days, tumors had developed in all of the plants.

He took one of the 10 infected plants and simply fashioned around the center of the plant a heavy copper wire in a single-loop, open-ended coil about 30 cm (12") in diameter. and held it in place with an ebonite stake. The copper coil acted as an antenna or tuning coil collecting and concentrating oscillation energy from extremely high frequency cosmic rays.

The diameter of the copper loop determined the range of frequencies to be captured. He found that the 30 cm loop captured frequencies that fell within the resonant frequency range of the plant's cells.

This captured energy reinforced the natural vibrational oscillations produced by the nucleus of the geranium cells. This slight “push” on the “swing” allowed the plant to damp the oscillations of the cancer cells and shifted the vibratory environment toward that of healthy plant cells. The tumors were gone in less than 3 weeks and by 2 months the plant was thriving. All of the other cancer-inoculated plants-without the antenna coil died within 30 days. In his book, Lakhovsky shows pictures of the recovered plant after 2 months, 6 months, and 1 year. Three years later, with the original coil still in place, the geranium had grown into a very healthy plant. His experimental observations were communicated to the French Academy of Science and the methods applied in nursing homes and hospitals in Europe.

Following on his geranium experiments, Lakhovsky then fashioned loops of copper wire that could be worn around the waist, neck, elbows, wrists, knees, or ankles of people (or animals) and he found that, given enough time, painful symptoms were relieved. These simple coils, worn continuously around certain parts of the body, would re-invigorate human cells and increase the immune response, which in turn took care of the offending pathogens. When news spread of the success achieved with these "Lakhovsky Coils," many Europeans clamored to one but often had to wait in turn for months. Many people find copper wrist bracelets effective and beneficial because the bracelet is functioning as a Lakhovsky Coil. (It's providing minute trace amounts of copper to the body, which helps too.)

In 1928, Professor Sordello Attilj, Director of the Radiological Service at the San Spirito Hospital in Sassia, Rome, Italy, reported to the Congress of Radiologists in Florence four cases, two sarcomas, one circulation problem in the hands and feet, and one severe back pain that made walking difficult. All four were quickly remedied with the Lakhovsky oscillating circuit.

The same year, Dr. Marcus in Paris reported that one of his patients, an insomniac, was given a Lakhovsky oscillation circuit and had slept soundly for the first time in a very long time. When the patient’s wife asked to try the device, she slept well but the patient relapsed into insomnia. When he retrieved the collar, he once again slept well.

Also in 1928, Dr. F. Barinque reported that after wearing a Lakhovsky device, a mastectomy patient whose progress was unsatisfactory, quickly improved and healed.

Dr. Barthe de Sandfort of Cannes reported he no longer suffered from arteritis obliterans, but what impressed him most was that nocturnal cramps no longer tortured him. So he tried the device on a relative who suffered from gastric problems. She wore it for one month and was relieved of pain.

Dr. C. Perineau of Paris reported that a patient with phlebitis of the legs and varicose ulcers improved after several months of wearing the Lakhovsky oscillating circuit. He also regained his appetite and sleep. When the device broke after a few months the disease recurred. A month later he got a new device and within a month the phlebitis disappeared. Lumbago in another of Dr. Perineau’s patients was relieved by a Lakhovsky oscillating circuit.

Sister Marie de L’Annonciation, a Franciscan nun and dispensary nurse at St. Joseph’s Orphanage, Deauville, France reported that “the greater number of my patients experience an unusual feeling of well-being as the result of wearing Lakhovsky’s oscillating circuit. One woman, aged 76, who for years had suffered from rheumatic pains, necessitating frequent injections, has had no further need of my care since she egan wearing a Lakhovsky’s oscillating circuit a month ago She tells me that she feels 20 years younger”

Sister Marie then used the device on herself and her other patients. Madame T. had suffered from pains of the back and varicose veins for thirty years which made housekeeping painful. “Since wearing a Lakhovsky oscillating circuit all her symptoms have vanished and she looks much younger.”

Madame L. “suffered from rheumatism since the age of 40. For years she had difficulty in walking…” She put on a Lakhovsky oscillating device and has not taken it off since. All other forms of treatment have been abandoned.” “She can now go for short walks and sleeps well at night. She says that she feels 20 years younger.”

Monsieur PL age 41 suffered from gouty rheumatism for some years until he tried a Lakhovsky device and his condition is steadily improving. Madame L recovering from a uterine hemorrhage and subsequently suffered pelvic pains, poor circulation, edema, fainting, lassitude, and sleeplessness. Wearing the device she improved rapidly and all her symptoms disappeared. Miss S. experienced dull pains following an appendectomy. These symptoms disappeared after a few days with the collar device. Madame H. had phlebitis. After only a few days wearing a Lakhovsky oscillating circuit, her leg was normal. When the device broke, the leg swelled again until the device was fixed.

Dr. Raul Araujo, a physician at the Prophylactic Institute in Montevideo, Uruguay was suffering from a longstanding infection of the larynx which medical doctors had not been able to cure. While in Paris in 1929, Dr. Araujo met Lakhovsky who advised him to try wearing a copper collar to set up a frequency of oscillation to resonate with his laryngeal tissues. He wore this collar for several months after which the infection disappeared and never recurred. Dr. Araujo determined to try this amazing, simple technology with his own patients. After treating more than 300 patients, he reported successfully mitigating and curing cases of rheumatism, asthma, anemia, neuralgia, gastric ulcer, colitis, glandular disturbances, sterility, genito-urinary afflictions, general weakness and even cancer. He found that circulation improved, blood count be came normal in a short time, sleep was improved and capacity for work increased. Eyes became brighter: face and lips acquired a healthy color. Falling out and graying of the hair was stopped. Cancer patients life was lengthened with a much improved general condition. Neurasthenia, insomnia, and incoherence disappeared and patients regained their mental equilibrium.

He found that in cases in which the Lakhovsky oscillating circuit seemed to give no results invariably involved latent infection which required special treatment such as syphilis, cholecystitis, sinusitis, pyelitis, and dental sepsis.

In 1931 Dr. P. Rigaux published Dr. Araujo’s findings in a monograph entitled, “Cosmic Rays and Oscillating Circuits”

The publication of the English version of The Secret of Life at the very outbreak of World War II went unnoticed and little reviewed, but Lakhovsky's reputation for obtaining dramatic results with his amazing Multi-Wave Oscillator gained world wide attention nevertheless. By 1941, he had moved to New York, escaping the Nazi occupation of France.

Dr. N. Vaccaro reported that a surgical patient was not recovering well until he fitted her with a Lakhovsky collar. A few months later she returned to get another collar, the first having broken. “She stated that her weakness, dyspepsia, and insomnia had vanished about a week after putting on the collar.” After less than 9 months she had recovered fully and was going back to work. “She now never leaves her ‘talisman’, as she calls her collar, and has a reserve supply of three other collars in case of an accident

Dr. E.Cincin of Seine-et-Oise reported that, following surgery for sarcoma of the ovary, a patient complained of edema, abdominal pains and general fatigue. After wearing the Lakhovsky’s oscillating circuit constantly her symptoms disappeared and her health has never been better.

In 1931, Lakhovsky introduced the Multiple Wave Oscillator at the Hospital St. Louis, Paris and Hospital Clinic at Goeteborg, Sweden, and later at the Institut de Physique Biologique in Paris. Among the medical conditions remediated are various cancers, exophthalmic goiter, enlarged prostate, gastrointestinal ulcer and other afflictions. Dr. Henry of Brussels and Professor de Cigna of Genoa successfully treated patients with the Multi-Wave Oscillator.

Dr Nicholas Gentile of Rome published an extract from the medical review, Medicina Nuova in 1935 in which he described successful treatment with the Multi-Wave Oscillator for cephalalgia from violent trauma in 3 sessions, encephalitis in 3 months, alcoholic paraplegia after 8 sessions, nocturnal enuresis after “a few” sessions, ovaritis and salpingitis after 2 months of sessions, enlarged prostate after 4 sessions, two cases of rapidly progressive baldness after 8 sessions. Dr. Gentile also successfully treated patients for arthritis, menstrual disorders, perivisceritis, diminution of glycemia and glycosuria in diabetic patients, hepatic colic, renal colic, chronic atonic or spastic constipation, asthma (but not cardiac asthma), reducing systolic blood pressure while increasing diastolic blood pressure, and chronic phlebitis (although not for acute phlebitis).

In 1940, Dr. Alexander Francis at Frinton-on-Sea reported,

“I have discovered that the Multi-Wave Oscillator improves hearing, and for the last 3 months the chief part of my work with the apparatus has been in deaf cases.”

I have been doing ear work for over 40 years and am very pleased to find at last something which is a real help in chronic deafness. I have obtained many striking results.

My best results are in nerve cases. A patient of mine who fell on his back seven years ago and has been completely paralyzed from the waist ever since is distinctly better. He had depended entirely on a catheter but for the past few months h3e has been able to pass water naturally. Sensation is returning to his legs and he feels very much better generally.

Mark Clement, in The Waves that Heal, describes how Lakhovsky was approached by many people and organizations hoping to capitalize on his Multi-wave Oscillator therapy. Lakhovsky was also approached by several hospitals in New York hoping to test his apparatus.. Remarkable results were obtained from a seven-week clinical trial at a major New York City hospital and by a prominent Brooklyn urologist in the summer of 1941. Later editions of The Secret of Life detailed many of these cases.

What seemed to be a promising development in the use of the Multi-Wave Oscillator in America quickly faded after Lakhovsky unexpectedly died in New York in 1942 at the age of 73. His equipment was removed from the hospital and patients were told that the therapy was no longer available. Except for this brief trial in New York, Lakhovsky's work remained completely unknown to the American public. Even the spectacular success of the New York cases was quickly shelved. Hidden hands were obliterating the memory of Lakhovsky's Multi-Wave Oscillator in America.

Lakhovsky's name and achievements probably would have remained unknown in America had it not been for Dr. Bob Beck, D. Sc. In 1963, he found an original Lakhovsky Multi-Wave Oscillator stored in the basement of a well-known hospital in southern California. He undoubtedly examined Lakhovsky's US patent # 1,962,565, as well. He then wrote a series of articles which were published in the Borderlands Journal that explained how it worked. A number of people began building their own Multi-Wave Oscillators based on Beck's articles in Borderlands. In 1986, Borderlands put together a big manual called The Lakhovsky Multiple Wave Oscillator Handbook which was updated and revised, most recently in 1994. The Handbook includes a compilation of informative articles by many authoritative researchers on the Multi-Wave Oscillator, including translated articles by Lakhovsky himself.

The Multi-Wave Oscillator works by producing a broad range of high frequency pulsed signals that radiate energy into the patient via two round resonators: one resonator acting as a transmitter and the other as a receiver. The resonator is constructed from a series of open ended circular copper tubes terminated with ball shaped knobs. The copper tube rings nest one inside the other, but none touch each other. The ring assembly is held in place with silk thread in Lakhovsky's original design. Each ring has its open ended termination placed 180 degrees opposite from its adjacent ring. The machine generates a very wide spectrum of high frequencies coupled with static high voltage charges applied to the resonators using spark gaps.. These high voltages cause a corona discharge around the perimeter of the outside resonator ring that Nikola Tesla referred to as an "electric brush", but Lakhovsky used the French word, "effluvia" or "effluve". The patient sat on a wooden stool in between the two resonators and was exposed to these energies for about 15 minutes. These amplified, artificially-produced, multiple-frequency waves sped up the recovery process by stimulating the resonance of healthy cells in the patient and in doing so, increased the immune response to the disease organisms.

Lakhovsky’s early experiments with radio frequency generators used a device he called the Radio Cellular Oscillator, but later switched to an older 19th century design static generator called a Rhumkorff Coil which was able to sufficiently excite the resonator coils while avoiding the potential for thermal damage to the patient.. The Multi-Wave Oscillator produced fundamental waves from 750,000 cycles per second up to 3 billion cycles per second with the harmonics of these fundamental frequencies extending the covered range much higher yet.

His work has been criticized by physicists ignorant of biology and biologists ignorant of physics. Neither seemed to understand the irrespective of their knowledge, SCIENCE depends upon empirical evidence gained by observation and experimentation. Theory and knowledge must fit the results, not the other way around.

From this history of electromagnetic invention, comes the VIBEmachine of Gene Koonce, who, like Lakhovsky, is an electrical engineer with an inquiring mind and a big heart

© 2004, Allen Aslan Heart / White Eagle Soaring of the Little Shell Pembina Band, a Treaty Tribe of the Ojibwe Nation.

http://www.vibemachine.com/

watch 20 minute video introduction by the inventor of the Vibe Machine, Gene Koonce.

VIBE Machine Interview With Gene Koonce

Interview with the inventor of the VIBE Machine in Greeley, Colorado.

From: Dekertek
Views: 14,798
Added: 1 year ago
Time: 18:33

Mark said...

Using "Zeta Potential" as a Healing Tool
Zeta Potential is a measure of the electrical force that exists between
atoms, molecules, particles, suspensoids, cells, etc., in a fluid.

here:
http://www.hbci.com/~wenonah/new/mcdaniel.htm


Zeta Potential's strength determines the amount of material that a fluid can carry. Increasing the electrical force in the solution, allows the fluid to dissolve and hold more material. In this way, deposits can be removed from many things.

Hundreds of industries work with Zeta Potential to control their chemical reactions. Dr. T.C. McDaniel learned of this, and applied the concepts to cardiovascular disease — his own. He then prescribed this technology for about ten thousand of his patients with excellent results. — Tommy Cichanowski —

Dr. T.C. McDaniel

My Goals: "I desire to get this basic information to professional practitioners, in order to improve our system of medicine, surgery, and midwifery, and to place the same on a more rational and scientific basis." — Dr. T.C. McDaniel —

* No Need For Heart By-Pass Operations !!!
* No Need for Balloon Angioplasty procedures !!!
* No Need to Replace Heart Valves because of Plaque Deposits !!!
* No Need to Amputate limbs because of Poor Circulation !!!
* Remove Kidney Stones in about 6 Hours in the Doctor's Office !!!
* Arrhythmias corrected in less than 2 hours !!!

Heart By-Pass Operations are No Longer Needed !
A Safer Method Can Be Used.

Have you or someone you know been told that a "Heart By-Pass Operation" is needed?

Thanks to today's advanced science, "By-Pass Operations" are no longer necessary.

It is now possible to remove blockages and mineral plaque from blood veins and arteries by simply administering a series of safe IVs prepared with chemistry that has been approved by the FDA. The IVs are Engineered to change the electrical properties of blood, and in so doing with the help of water, can bring deposits back into solution. Depending on the severity of one's condition, approximately 24 IVs are administered over the course of 2 to 3 months. ( Additionally, in Germany and elsewhere, the pineapple enzyme bromelaine is being successfully used to disassemble the fibrous component of circulatory plaque deposits. )

This technique has been developed over the last twenty years and has produced successful results for more than 10,000 patients who have sought help from Dr. T.C. McDaniel at his clinic in Cincinnati. Dr. McDaniel was inspired by the late industrial chemist Thomas M. Riddick, who developed coronary problems himself, and had undertaken a complex study of blood chemistry.

After a three-day visit to Dr. McDaniel's clinic for diagnosis, tests and health maintenance classes, any Registered Nurse, even in your home if desired, can administer the remaining IVs for you. Each patient is unique and the IVs are individually prepared for the needs of each person, based on blood and urine tests.

If you are willing to make the necessary changes in your lifestyle, additional treatments will not be required. ( A very large number of people, who have had one heart by-pass operation, often require another after a short time, even when on medications. Also, Nova's "When Wonder Drugs Don't Work" reports that approximately 548 patients each day are infected by "drug resistant" bacteria in U.S. hospitals. )

Dr. McDaniel has also saved the limbs of patients who were told by other doctors that amputation of a limb was necessary. (usually a leg)*
[ * Diabetes often results in reduced circulation in the extremities. Hands and feet that are always cold, soon can be warm again. This treatment also increases the effectiveness of Insulin, helping to improve blood sugar regulation. Some patients have even managed to eliminate the need for Insulin injections altogether. ]

This therapy is biased on an understanding of the electro–chemical properties of blood.

We are addressing the chemical issues, which result in internal blood clotting and mineral deposits within the cardiovascular system.

Thomas M. Riddick, an Industrial Chemist, is credited with doing the first major study of how "Zeta Potential" controls the chemical processes in our bodies. Using this science, we can reverse and correct many "Blood Plasma Problems".



Dr. McDaniel holds seminars for doctors who want to study this science.

— Dr. T.C. McDaniel —

Voted: Outstanding Graduate of the Century by Eastern Kentucky University ( 1972 )

Past member Kentucky State Board of Health

Past member Kentucky State Board of Medical Licensure (appointed by 4 different Governors)

Past President, The Kentucky Osteopathic Medical Association

Past President, Cincinnati Academy of Osteopathic Medicine

Past president, American Society of Bariatric Physicians

Private practice: Cardiovascular–Renal Diseases, Rehabilitative Medicine, Cincinnati, OH ( 1983 – present )

Author:

"The Wheel of MisFortune" – multiple diseases that are out of control.
"Disease Reprieve" – Living Into The Golden Years without physiological bankruptcy.

Degrees: AB, MA, D.O.

Primary areas of treatment: Blood clots, high blood pressure, circulatory disorders, arrhythmia, kidney stones, peripheral vascular diseases, chronic fatigue, Crohn's Disease, ...




"Sometimes We Forget to Inspect Our Foundations"

As Healers, we need to always remember two important concepts.

1. Our bodies, indeed our whole carbon based bio-system, is mainly composed of Water.
2. Our body's nervous system and all chemical reactions and relationships require and operate with the " Electric Force".

If there isn't enough water in our body's system to allow the electric force to operate properly, or if the electrical force is out of balance because of excesses or deficiencies in our blood plasma electrolytes, disease can result.

The "Foundation For Good Health" lies in maintaining the proper "Hydro-Electric Properties" in our blood plasma, intra-cellular and extra-cellular fluids. These liquids provide the playing field for all the chemical reactions needed to power our bodies and must be kept in balance for good health.

From the view point of medical intervention, for many diseases, we need to focus on the kidneys and their related systems. One can use a specific conductance meter to determine the total dissolved solids of the urine. This measurement gives one a good indication of the stress load that the kidneys are under and offers a starting point for treatment. Most of the time, the first step is to re–hydrate the patient to lower the "electrical work load" resulting from high osmotic pressures in the kidneys.

When the kidneys are operating in a "safe range", determined through specific conductance measurements, focus can be directed toward fine-tuning the blood plasma electrolytes.

Once plasma electrolytes are balanced, blood pressure will come down, circulation will improve, and arrhythmias will disappear.

Removal of "blood plasma build-ups" and rehydration is quickly accomplished using a mineral enhanced IV with adjusted electrical properties. This method should be considered as the first course of treatment for appropriate disease conditions. It should be obvious that any other treatments won't truly be effective unless these basic systems are balanced first.

Fine-tuning of the therapy can then be accomplished using "blood work–up tests" with due consideration of plasma electrolytes and trace elements.

At home maintenance involves dietary changes with special emphasis placed on drinking enough pure water with less than 10 ppm of dissolved solids. Also, avoidance of aluminum has special importance because of the unwanted electrical properties aluminum has in water solutions. The use of an oral saline solution is encouraged to booster plasma electrolytes until the body is stable, and re–hydrated, and the patient has learned natural methods of self-maintenance.

Many times, simple dietary changes and treatments can have a dramatic effect on health and personal energy levels. Sometimes — many times simple is the best way to go and should always be used first before doing something more complex or using something that has side–effects.

Our space age technology has given us many incredible new measurement devices. These devices can give us a very objective look at human chemical processes. The tools and the understanding of new concepts have evolved together. It is time now to stop and absorb the work of the many diverse disciplines that have something to offer to the field of "The Healing Arts".




It's A Long, Long Way From Los Alamos,
to The Mayo Clinic!
by Tommy Cichanowski

A few years back, our government instituted a "Technology Transfer Program" to help get research information from the "National Labs" into the commercial sector. I have worked with the program commercially in the fields of advanced materials and microwave technology.

Considerable work has already been done and is continuing at our National Laboratories with Advanced Materials. To be able to work in this exotic field of science, one needs to have a complete knowledge of how atoms connect and interact with each other to form molecules in many different situations. This knowledge is also needed in the field of Hydroculture where we need to keep atoms in solution in a water medium.

The science used in this advanced work, also has applications in the field of health care. It is the Electric Force that keeps blood cells from "Clumping" and mineral salts in solution. Understanding how to manipulate the "Silver Balls" we call electrons gives us new options for treating diseases

Health Care issues can be addressed using the "sub-science" of "Colloidals". Colloidal Science allows us to study the "Electrical Properties" of solutions, like our blood and urine. This electrical property is called "Zeta Potential". Since Zeta Potential is a subject normally contained within Colloid Chemistry, very few health professionals are even aware of it and its potential importance to human health.

Nearly deceased at age 56, now 91 years old, Dr. T.C. McDaniel has learned to use this "Atomic Electrical Knowledge", Anionic Surfactants, and the "Power of Pure Water", in the treatment of many different diseases. He has successfully treated himself and about 10,000 patients. Dr. T.C. McDaniel now conducts a full–time medical practice in Cincinnati, Ohio and is sharing what he has learned from his studies of Zeta Potential with his patients and health care professionals.

Dr. T.C. McDaniel has a three-day Seminar for Physicians, covering the principles of Anionic Surfactant Therapy in great detail, allowing them to incorporate this effective new program into their practice. You should call the office for more details. It will be a call you won't regret.

It is indeed a sobering thought that with proper intake of "Pure Water" ( Reverse Osmosis or distilled water ) containing appropriate blood plasma electrolytes, irregular heartbeats, including Paroxysmal Tachycardia, can be stabilized without electric cardioversion.

Most patients can be stabilized in route to the hospital and expensive procedures avoided. Physicians take an oath "To Do No Harm". I hope that covers using the simplest course of treatment first.

Learning a few, new simple concepts, will allow Physicians to become very effective in their treatment programs resulting in great job satisfaction.



Zeta Potential / Colloidal Science Overview
"Zeta Potential" is expressed as voltage —
Electricity:

Mother Nature's Atomic Anti-Collision System

Visualize: "Atomic Personal Space" - Elbow Room For Atoms and Molecules

A place where One can just hang out and be "One's-Self".



Colloidal Science:

Unveils answers and concepts, Calibrates meters, Describes new possibilities.

Have you ever wondered why those ever moving, hyperactive atoms don't just crash into each other and form a big ball? Why your hydroculture salts stay in solution sometimes and not others? Why very weak and very strong solution concentrations BOTH tend to lose salts? (precipitates i.e., settles) Why that white stuff collects on your glassware and flower vases?

Whether a quantity of clay, added to a liter of distilled water containing mineral salts, will form an adhesive mass or disperse into trillions of tiny particles, each remaining separate and discrete, depends almost entirely on the electrical properties of the system. Like electrical charges repel each other, and the strength of this Electric Force controls many of the factors of chemistry.

It is this Electric Force that keeps atoms and molecules from colliding with each other, allows them to remain discrete, and it is this "Electric Force" that needs to be overcome when you are endeavoring to hook atoms together to form new advanced materials.

Atoms are very much like miniature solar systems with their electrons in orbits similar to planets and comets. The electrons are moving so fast, that only a blur is seen by our test instruments, and this blurry area where the electrons "hang out" is called the Electron Cloud, sometimes referred to as the atom's "Virtual Electron Shell".

How these shells interact with each other can be observed with the tools used in the field of Colloidal Science. Understanding how to use these concepts, allows us to create a root environment for plants, where the nutrient salts stay in solution at the right concentration and allows us to also, measure and control the electrical properties of our blood and urine, allowing us to resolve most circulatory problems.

This Electrical Knowledge, Anionic Surfactants, and the Power of our world's most universal solvent "Pure Water", allows us to remove unwanted, harmful materials from our bodies. i.e. kidney stones, blood clots, minerals, etc.

The idea behind good health is simple. Wash out the body's toxins, and give the body enough water to fully hydrate its blood plasma so that our bodies can relax and our blood can carry food and oxygen to all of our body's cells, resulting in a more efficient vigorous body.

AGAIN — The foundation of good health lies in maintaining the proper "Hydro-Electric Properties" in our blood plasma, intra-cellular and extra-cellular fluids. These liquids provide the playing field for all the chemical reactions needed to power our bodies and must be kept in balance for good health.



— Dr. T.C. McDaniel 's Contact Information —

7436 Vine Street
Cincinnati, Ohio 45216
Off. 1–513–761–3307
Fax: 1–513–761–4588



* No More Heart Attacks

* No More Infarctions

* No More Arrhythmias

* No More Kidney Stones

* No More Lithotripsy

* No More Deep Venous Thrombosis

Take Charge of Your Own Health Decisions !



Dr. McDaniel learned the basic science for his program from this book ...
" Control of Colloid Stability through Zeta Potential "

With a closing chapter on

Zeta Potential's Relationship to Cardiovascular Disease.
by Thomas M. Riddick



The Science of "Zeta Potential" is used by Hundreds of different industries. This knowledge is used to improve many things and processes; from concrete to beer, and much much more ...

Scirus is a powerful new Search Engine for locating scientific information. Searching for "Zeta Potential" on Scirus, returns a count of almost 10,000 different web pages relating to the subject of Zeta Potential.



NOTE: All Reverse Osmosis units are not the same. You should look for one that can output water with a Total dissolved solids in the range of 5–20 ppm, or a specific conductance of 10–40 microsiemens or less.
Two thirds of the elemental salts used in hydroculture would be Toxic to plants (and humans) if included in the solution at levels of 4 ppm.

---
http://www.hbci.com/~wenonah/new/mcdaniel.htm

Mark said...

9 steps to detoxify from mercury fillings, and more


The Klinghardt Neurotoxin Elimination Protocol


Approved by:
American Academy of Neural Therapy and
Institute of Neurobiology (Bellevue, WA, USA)
Institute for Neurobiologie (Stuttgart, Germany)
Academy for Balanced NeuroBiology Ltd (London, United Kingdom)

This lecture was presented by Dietrich Klinghardt M.D., Ph.D. at the Jean Piaget Department at the University of Geneva, Switzerland Oct. 2002 to physicians and dentists from Europe, Israel, several Arab countries and Asia.


What are Neurotoxins?

Neurotoxins are substances attracted to the mammalian nervous system. They are absorbed by nerve endings and travel inside the neuron to the cell body. On their way they disrupt vital functions of the nerve cell, such as axonal transport of nutrients, mitochondrial respiration and proper DNA transcription.

The body is constantly trying to eliminate neurotoxins via the available exit routes — the liver, kidney, skin and exhaled air. Detox mechanisms include acetylation, sulfation, glucuronidation, oxidation and others. The liver is most important in these processes. Here most elimination products are expelled with the bile into the small intestine and should leave the body via the digestive tract. However, because of the lipophilic/neurotropic nature of the neurotoxins, most are reabsorbed by the abundant nerve endings of the enteric nervous system (ENS) in the intestinal wall. The ENS has more neurons than the spinal chord. From the moment of mucosal uptake the toxins can potentially take 4 different paths:

1. Neuronal uptake and via axonal transport to the spinal chord (sympathetic neurons) or brainstem (parasympathetics) — from here back to the brain.

2. Venous uptake and via the portal vein back to the liver.

3. Lymphatic uptake and via the thoracic duct to the subclavian vein.

4. Uptake by bowel bacteria and tissues of the intestinal tract.


Here is an incomplete list of common neurotoxins in order of importance:

1. Heavy metals — such as mercury, lead, cadmium and aluminum.

2. Biotoxins — such as tetanus toxin, botulinum toxin (botox), ascaridin (from intestinal parasites), unspecified toxins from streptococci, staphylococci, lyme disease, clamydia, tuberculosis, fungal toxins and toxins produced by viruses. Biotoxins are minute molecules (200–1000 kilodaltons) containing nitrogen and sulfur. They belong to a group of chemical messengers, which microorganisms use to control the host's immune system, host behavior and the host's eating habits.

3. Xenobiotics (man-made environmental toxins) — such as dioxin, formaldehyde, insecticides, and wood preservatives, PCBs etc.

4. Food Preservatives, excitotoxins and cosmetics — such as aspartame (diet sweeteners) food colorings, fluoride, methyl-and propyl-paraben, etc.

I have found that mercury in it's different chemical forms has a synergistic amplifying effect with all other neurotoxins. When mercury is removed, the body starts to more effectively eliminate all other neurotoxins, even if they are not addressed.


What are the Symptoms?

Any illness can be caused by, or contributed to, or exaggerated by neurotoxins. Fatigue, depression, insomnia, memory loss and blunting of the senses are common early symptoms (See list of mercury related symptoms on the following pages).


How is the Diagnosis Established?

1. History of Exposure: (Did you ever have any amalgam fillings? A tick bite? etc)

2. Symptoms: (How is your short term memory? Do you have areas of numbness, strange sensations, etc?)

3. Laboratory Testing: (Metals, hair, stool, serum, whole blood, urine analysis, xenobiotics, fatty tissue biopsy and urine)

4. Autonomic Response Testing (Dr. Dietrich Klinghardt M.D., Ph.D.)

5. BioEnergetic Testing (EAV, kinesiology, QXCI etc.)

6. Response to Therapeutic Trial

7. Functional Acuity Contrast Test (measure of Retinal Blood Flow)


TREATMENT

Why would we want to treat anyone at all? Is it really needed? Can the body not eliminate these toxins naturally on its own?

Here is a short list of independent risk factors, which can either cause accumulation of metals in an otherwise healthy body — or slow down, or inhibit the body's own elimination processes.

* Genetics
* Occupational exposure to toxic material
* Prior illnesses
* Surgical operations
* Medication or "Recreational" drug use
* Emotional trauma, especially in early childhood
* Social status
* High carbohydrate intake combined with protein malnutrition (especially in vegetarians)
* Use of homeopathic mercury
* Food allergies
* The patient's electromagnetic environment (mobile phone use, home close to power lines etc.)
* Constipation
* Compromise of head/neck lymphatic drainage (sinusitis, tonsil ectomy scars, poor dental occlusion)
* Number of dental amalgam fillings over the patient's lifetime, The number of amalgam fillings the patient's mother had.

We will discuss here only those elimination agents, which are natural, safe and have also been shown to be as effective (or more effective) than the few available pharmaceuticals. Because these products cannot be patented and exploited for unethical personal gain, little attention has been given to them by European or North American medical researchers. Many of the best scientific studies on this topic are from Asian countries.


The Basic Program

High protein, mineral, fatty acid and fluid intake

Rationale:

* Proteins provide the important precursors to the endogenous metal detox and shuttle agents, such as coeruloplasmin, metallothioneine, glutathione and others. The branched-chain amino acids in cow and goat whey have valuable independent detox effects.
* Metals attach themselves only in places that are programmed for attachment of metal ions. Mineral deficiency provides the opportunity for toxic metals to attach themselves to vacant binding sites. A healthy mineral base is a prerequisite for all metal detox attempts (selenium, zinc, manganese, germanium, molybdenum etc.). Substituting minerals can detoxify the body by itself. Just as important are electrolytes (sodium, potassium, calcium, magnesium), which help to transport toxic waste across the extra-cellular space towards the lymphatic and venous vessels.
* Lipids (made from fatty acids) make up 60–80% of the central nervous system and need to be constantly replenished. Deficiency makes the nervous system vulnerable to the fat soluble metals, such as metallic mercury constantly escaping as odorless and invisible vapor evaporating from the amalgam fillings.
* Without enough fluid intake the kidneys may become contaminated with metals. The basal membranes swell up and the kidneys can no longer efficiently filtrate toxins. Adding a balanced electrolyte solution in small amounts to water helps to restore intra-and extra-cellular fluid balance


Cilantro (Chinese Parsley)

This kitchen herb is capable of mobilizing mercury, cadmium, lead and aluminum in both bones and the central nervous system. It is probably the only effective agent in mobilizing mercury stored in the intracellular space (attached to mitochondria, tubulin, liposomes etc) and in the nucleus of the cell (reversing DNA damage of mercury). Because cilantro mobilizes more toxins then it can carry out of the body, it may flood the connective tissue (where the nerves reside) with metals, that were previously stored in safer hiding places.

This process is called re-toxification. It can easily be avoided by simultaneously giving an intestinal toxin-absorbing agent. Our definite choice is the algal organism chlorella. A recent animal study demonstrated rapid removal of aluminum from the skeleton superior to any known other detox agent.

Dosage and application of cilantro tincture: give 2 drops 2 times per day in the beginning, taken just before a meal or 30 minutes after taking chlorella (cilantro causes the gallbladder to dump bile — containing the excreted neurotoxins — into the small intestine. The bile-release occurs naturally as we are eating and is much enhanced by cilantro. If no chlorella is taken, most neurotoxins are reabsorbed on the way down the small intestine by the abundant nerve endings of the enteric nervous system). Gradually increase dose to 10 drops 3 times/day for full benefit. During the initial phase of the detox cilantro should be given 1 week on, 2–3 weeks off.

Other ways of taking cilantro: rub 5 drops twice/day into ankles for mobilization of metals in all organs, joints and structures below the diaphragm, and into the wrists for organs, joints and structures above the diaphragm. The wrists have dense autonomic innervation (axonal uptake of cilantro) and are crossed by the main lymphatic channels (lymphatic uptake).

Cilantro tea: use 10 to 20 drops in cup of hot water. Sip slowly. Clears the brain quickly of many neurotoxins. Good for headaches and other acute symptoms (joint pains, angina, headache). Or, rub 10–15 drops into painful area. Often achieves almost instant pain relief.


Chlorella

Both C. Pyreneidosa (better absorption of toxins, but harder to digest) and C. Vulgaris (higher CGF content — see below, easier to digest, less metal absorbing capability) are available. Chlorella has multiple health inducing effects:

* Antiviral (especially effective against the cytomegaly virus from the herpes family)
* Toxin Binding (mucopolysaccharide membrane) all known toxic metals, environmental toxins such as dioxin and others
* Repairs and activates the body's detoxification functions
* Dramatically increases reduced glutathion
* Sporopollein is as effective as cholestyramin in binding neurotoxins and more effective in binding toxic metals than any other natural substance found.
* Various peptides restore coeruloplasmin and metallothioneine.
* Lipids (12.4%) alpha-and gamma-linoleic acid help to balance the increased intake of fish oil during our detox program and are necessary for a multitude of functions, including formation of the peroxisomes.
* Methyl-coblolamine is food for the nervous system, restores damaged neurons and has its own detoxifying effect.
* Chlorella growth factor helps the body detoxify itself in a yet not understood profound way. It appears that over millions of years chlorella has developed specific detoxifying proteins and peptides for every existing toxic metal.
* The porphyrins in chlorophyll have their own strong metal binding effect. Chlorophyll also activates the PPAR-receptor on the nucleus of the cell which is responsible for the transcription of DNA and coding the formation of the peroxisomes (see fish oil), opening of the cell wall (unknown mechanism) which is necessary for all detox procedures, normalizes insulin resistance and much more. Medical drugs that activate the PPAR receptor (such as pioglitazone) have been effective in the treatment of breast and prostate cancer.
* Super nutrient: 50–60% amino acid content, ideal nutrient for vegetarians, methylcobolamin — the most easily absorbed and utilized form of B12, B6, minerals, chlorophyll, beta carotene etc.
* Immune system strengthening
* Restores bowel flora
* Digestive Aid (bulking agent)
* Alkalinizing agent (Important for patient's with malignancies)


Dosage: start with 1 gram ( = 4 tab.) 3–4 times/day. This is the standard maintenance dosage for grown ups for the 6–24 months of active detox. During the more active phase of the detox (every 2–4 weeks for 1 week), whenever cilantro is given, the dose can be increased to 3 grams 3–4 times per day (1 week on, 2–4 weeks back down to the maintenance dosage). Take 30 minutes before the main meals and at bedtime. This way chlorella is exactly in that portion of the small intestine where the bile squirts into the gut at the beginning of the meal, carrying with it toxic metals and other toxic waste. These are bound by the chlorella cell wall and carried out via the digestive tract.

When amalgam fillings are removed, the higher dose should be given for 2 days before and 2–5 days after the procedure (the more fillings are removed, the longer the higher dose should be given). No cilantro should be given around the time of dental work. During this time we do not want to mobilize deeply stored metals in addition to the expected new exposure.

If you take Vitamin C during your detox program, take it as far away from Chlorella as possible (best after meals).

Side effects: most side effects reflect the toxic effect of the mobilized metals, which are shuttled through the organism. This problem is instantly avoided by significantly increasing the chlorella dosage, not by reducing it, which would worsen the problem (small chlorella doses mobilize more metals than are bound in the gut, large chlorella doses bind more toxins than are mobilized). Some people have problems digesting the cell membrane of chlorella. The enzyme cellulase resolves this problem.

Cellulase is available in many health food stores in digestive enzyme products. Taking chlorella together with food also helps in some cases, even though it is less effective that way. C. Vulgaris has a thinner cell wall and is better tolerated by people with digestive problems. Some manufactures have created cell wall free chlorella extracts (NDF, PCA), which are very expensive, less effective — but easily absorbed.


Chlorella Growth Factor

This is a heat extract from chlorella that concentrates certain peptides, proteins and other ingredients. The research on CGF shows that children develop no tooth decay and their dentition (maxillary-facial development) is near perfect. There are less illnesses and children grow earlier to a larger size with higher I.Q and are socially more skilled. There are case reports of patients with dramatic tumor remissions after taking CGF in higher amounts. In our experience, CGF makes the detox experience for the patient much easier, shorter and more effective.

Recommended dosage: 1 cap. CGF for each 20 tab. chlorella


Garlic (Allium Sativum) and Wild Garlic (Allium Ursinum)

Garlic has been shown to protect the white and red blood cells from oxidative damage caused by metals in the blood stream — on their way out — and also has its own valid detoxification functions. Garlic contains numerous sulphur components, including the most valuable sulph-hydryl groups, which oxidize mercury, cadmium and lead and make these metals water-soluble. This makes it easy for the organism to excrete these substances.

Garlic also contains alliin which is enzymatically transformed into allicin, natures most potent antimicrobial agent. Metal toxic patients almost always suffer from secondary infections, which are often responsible for part of the symptoms. Garlic also contains the most important mineral, which protects from mercury toxicity, bioactive selenium. Most selenium products are poorly absorbable and do not reach those body compartments in need for it. Garlic selenium is the most beneficial natural bio-available source. Garlic is also protective against heart disease and cancer.

The half-life of allicin (after crushing garlic) is less then 14 days. Most commercial garlic products have no allicin releasing potential left. This distinguishes freeze-dried garlic from all other products. Bear garlic tincture is excellent for use in detox, but less effective as antimicrobial agent.

Dosage: 1–3 capsules freeze dried garlic after each meal. Start with 1 capsule after the main meal per day; slowly increase to the higher dosage. Initially the patient may experience die-off reactions (from killing pathogenic fungal or bacterial organisms). Use 5–10 drops bear-garlic on food at least 3 times per day.


Fish Oil

The fatty acid complexes EPA and DHA in fish oil make the red and white blood cells more flexible thus improving the microcirculation of the brain, heart and other tissues. All detoxification functions depend on optimal oxygen delivery and blood flow. EPA and DHA protect the brain from viral infections and are needed for the development of intelligence and eyesight. The most vital cell organelle for detoxification is the peroxisome. These small structures are also responsible for the specific job each cell has.

In the pineal gland the melatonin is produced in the peroxisome, in the neurons dopamine and norepinephrine, etc. It is here, where mercury and other toxic metal attach and disable the cell from doing its work. Other researchers have focused on the mitochondria and other cellorganelles, which in our experience are damaged much later.

The cell is constantly trying to make new peroxisomes to replace the damaged ones. For that task it needs an abundance of fatty acids, especially EPA and DHA. Until recently it was believed, that the body could manufacture its own EPA/DHA from other Omega 3 fatty acids such as fish oil. Today we know, that this process is slow and cannot keep up with the enormous demand for EPA/DHA our systems have in today's toxic environment.

Fish oil is now considered an essential nutrient, even for vegetarians. Recent research also revealed, that the transformation humans underwent when apes became intelligent and turned into humans happened only in coastal regions, where the apes started to consume large amounts of fish. Why not benefit from that knowledge and consume more fish oil?

The fatty acids in fish oil are very sensitive to exposure to electromagnetic fields, temperature, light and various aspects of handling and processing. Trans fatty acids, long chain fatty acids, renegade fats and other oxidation products and contaminants are frequently found in most commercial products. Ideally, fish oil should be kept in an uninterrupted cooling chain until it ends up in the patient's fridge. The fish-source should be mercury and contaminant free, which is becoming harder and harder.

Fish oil should taste slightly fishy but not too much. If there is no fish taste, too much processing and manipulation has destroyed the vitality of the oil. If it tastes too fishy, oxidation products are present. I recommend you use the product recommended below (grade I), where meticulous care has been taken to comply with all the necessary parameters. The clinical results are outstanding.

Dosage: 1 capsule Omega 3 taken 4 times/day during the active phase of treatment, 1 cap. twice/day for maintenance. Best if taken together with chlorella

The VegiPearls contain half the amount of EPA/DHA. The vegetarian capsules eliminate even the most remote possibility of containing prions and make the idea of taking fish oil more easily acceptable for vegetarians. Recently a fatty acid receptor has been discovered on the tongue, joining the other more known taste receptors. If the capsules are chewed, the stomach and pancreas start to prepare the digestive tract in exactly the right way to prepare for maximum absorption. Children love chewing the VegiPearls.

To treat bipolar depression, postpartum depression and other forms of mental disease, 2000 mg of EPA are needed/day (David Horrobin). For the modulation of malignancies, 120 mg of EPA 4 times/day are needed. The calculations can easily be done with the information given on the label.


Balanced Electrolyte Solution (Selectrolyte) or (Zeta Aid)

The autonomic nervous system in most toxic patients is dysfunctional. Electric messages in the organism are not received, are misunderstood or misinterpreted. Toxins cannot be shuttled through the extra-cellular space. Increased intake of natural ocean salt (Celtic sea salt) — and avoidance of regular table salt — has been found to be very effective in resolving some of these problems. Most effective is a solution pioneered by the American chemist Ketkovsky. He created the formula for the most effective electrolyte replacement, which was further improved by Morin Labs, and is now called "selectrolyte". I recommend this to all my patients and have observed, that every aspect of the detoxification process seems to be enhanced. 5% of the population is sodium or chloride sensitive — the blood pressure goes up (easily reversible). In these patients the detox process takes longer and is more difficult.

Dosage: 1 tsp in a cup of good water 1–3 times/day. During times of greater stress the dosage can be temporarily increased to 1 tbsp 3 times/day.

More aggressive approaches, such as I.V. Glutathione, Vitamin C, DMPS, Na2EDTA and others have a place in reasonably healthy people but often worsen the condition in patients with advanced illness.

Most valuable is the addition of psychotherapeutic interventions such as applied psychoneurobiology (APN) and mental field therapy (MFT) to trigger the release of toxins from their hiding places.

Chlorella, cilantro, garlic-products and fatty acids vary greatly in quality and nutrient content, also in content of contaminants. I no longer recommend BioReurella and other products that have not undergone or passed our quality control screening process.


Heavy metal detox has to be done carefully and right !!!


October 2002
Dietrich Klinghardt, MD, PhD
Bellevue, Washington, USA
www.neuraltherapy.com


9 Steps to Detox from Mercury Fillings
Prescribe for Yourself – You Must Learn To Be Your Own Best Doctor.

Eight amalgams in a single mouth can release 3–17 mcg of mercury per day.

1 mcg of mercury contains 120,827,403,000,000,000,000 atoms.
Each mercury atom can potentially destroy a nerve cell or lymphocyte blood cell.
Lymphocytes are the "back-bone" of our body's immune system.

While removal of amalgam fillings stops any further poisoning, you still need to detoxify your body to eliminate the residual effects of mercury.

Mercury is a toxic heavy metal and the chronic health problems associated with its use in dental fillings is very well documented in the scientific literature.

If you are planning to have your fillings removed, there are steps you can take to speed the mercury detoxification process, says Dietrich Klinghardt, M.D., Ph.D., an expert in mercury toxicity. Dr. Klinghardt and Louisa Williams, D.C., have developed a detoxification protocol to accompany the removal of mercury dental amalgams by a trained professional.

Preparation — Two months before the removal of the fillings, obtain a hair analysis to assess your mineral levels and supplement any minerals that are low. "Pay special attention to your levels of sodium and chloride, which typically are low in mercury–toxic patients," says Dr. Klinghardt.

Chlorella — The main agent used in the detoxification process is chlorella algae, which have been proven to bind with and remove toxic metals from the body. Take it at your highest comfortable tolerance level, advises Dr. Klinghardt. Chlorella supplementation can range from half a capsule to a maximum of 14 capsules daily, depending on individual tolerance. Too high a dose will cause symptoms of nausea, heartburn, diarrhea, and headache. For the first eight days, take the chlorella with meals at your maximum tolerance level, dividing it into small doses throughout the day. On days nine and ten, take ten times your usual dose, but not more than 60 capsules in a single day. Days 11 and 12 are a "rest" period and no chlorella should be taken on these days. The following day, begin the 12–day cycle again.

Garlic — Garlic contains compounds called sulfhydryl groups, which aid in the detoxification process by transporting mercury through the body, especially the kidneys, according to Dr. Klinghardt. For proper garlic supplementation, you must first determine your highest tolerance level for the herb. Dr. Klinghardt suggests using the "smell detection level" as a general guide: If you can smell the garlic on your breath, you're taking too much. As with chlorella, garlic should be taken in divided doses, with meals.

Cilantro — Studies have shown that cilantro or coriander ( Chinese parsley ) can help move mercury and other toxic metals out of the central nervous system for excretion through the urine or feces. To increase your intake of cilantro, Dr. Klinghardt suggests making this "pesto" to increase your intake of cilantro:

Start with fresh, organic cilantro and wash it thoroughly. Place the cilantro in blender, along with water, sea salt and olive oil. Blend the ingredients until creamy. Dr. Klinghardt recommends taking 1–3 tbsp of this cilantro pesto, three times daily with meals. For those suffering from neurological problems, such as Alzheimer's or brain "fogginess" and difficulty concentrating, the pesto may be taken more often, he says.

High–protein diet — "A high protein diet is essential to mercury detoxification," says Dr. Klinghardt.

Colonics — Have a colonic irrigation once weekly, as this helps in the elimination of mercury via the feces. When doing the protocol in conduction with chelation therapy ( see below ), increase frequency to twice weekly.

Additional supplements — Other helpful nutritional supplements include vitamin C and magnesium, which shorten the amount of time it takes for feces to pass through the bowel ( this prevents excreted mercury from being reabsorbed by the body through the intestine ); vitamin E; thioctic acid; and N–acetyl–cysteine.

On the day of mercury amalgam removal, take 20 capsules of chlorella immediately before the procedure. Following removal, open an additional two capsules and sprinkle the contents directly on your teeth, Dr. Klinghardt instructs. Keep the chlorella in your mouth for about ten minutes, to absorb any metal residues; after ten minutes, spit out the chlorella and rinse your mouth with water. Repeat this step that night as well. The following day, resume the regular program,

Eight amalgams in a single mouth can release 3–17 mcg of mercury per day Chelation — As a final step in eliminating residual mercury from the cells, chelation therapy is required to bind up the mercury and carry it out of the body. Dr. Klinghardt recommends that the chelating ( "binding" ) agent DMPS be used as soon as possible following mercury amalgam removal. The assistance of a professional dentist is required for this step.

This detoxification protocol should be continued until all symptoms of mercury toxicity have been eliminated, says Dr. Klinghardt. In some cases, this may take up to three or four years, although many have successfully completed the detoxification process in a shorter period of time.

Energizing Soak — This stimulating herbal bath is especially good for an energy boost after a long day.

3 tbsp dried nettle

3 tbsp dried red clover blossoms

2 tbsp dried peppermint

5 drops peppermint essential oil

5 drops rosemary essential oil

1 tsp distilled witch hazel

Place the dried herbs in the center of a piece of cloth like a cotton handkerchief. Gather the corners of the cloth together and tie with a piece of string, making a loop large enough to fit over your bathtub faucet.

Hang this herbal "teabag" from the faucet so that the bathwater runs through it. While you wait for the tub to fill, dilute the essential oils with the witch hazel to prevent any skin sensitivity to the concentrated oil. When the tub is full, add the essential oil mixture. ( Oils will dissipate too quickly if added while the hot water is still running. ) Swirl the water around with your hand to disperse the oils. Place the herbal teabag in the tub.

Dry–Brush Your Body — To enhance the effect of the bath, Vukovic recommends dry brushing your entire body before you step into the bathtub. Once you have entered the tub, soak for 15–20 minutes, adding additional hot water as needed to maintain a constant water temperature. For an increased energizing effect, follow this bath with a cold shower.

Contact: Dietrich Klinghardt, M.D., PhD.,

American Academy of Neural Therapy,

Phone: 206–749–9967, fax 206–723–1367

www.neurotherapy.com

On the day of amalgam removal, vitamin C should not be taken until after the procedure otherwise, it may interfere with anesthesia.

Heavy metal–related symptoms, such as joint pains, depression, burning sensations, digestive–related problems, and fatigue can be temporarily aggravated as DMPS removes toxins from the cells. The symptoms may change, but this is a transient occurrence. The routine use of intravenous DMPS is not advisable for patients who still have silver amalgam fillings. This is because DMPS may appear in the saliva and act to dissolve the surface of the existing amalgam fillings. The potential outcome is acute toxicity from heavy metal injury to the lining of the gut.

Originally posted at http://www.altemativemedicine.com/digest/issue29/29039ROO.shtml

Printed — 9/28/00

http://www.hbci.com/~wenonah/new/9steps.htm

Mark said...

INVENTION 2
A handheld pathologist

WHAT IT IS: A handheld device for cheaply and noninvasively monitoring some cancers

LEAD INVENTOR: Physicist Lydia Sohn, UC Berkeley

SNAPSHOT: With a disposable molded pore comparable to cancerous cells in size and shape, Sohn’s nanocytometer can filter through a drop of blood, detecting cancers in the circulatory system before they grow lethal.

FANTASY APP: Instant blood tests in every doctor’s office for every major cancer

THE STORY: Fourteen years ago, though she was interested in going to medical school, Sohn decided to pursue a PhD in physics at Harvard instead. Her postdoctorate work in the Netherlands led her to study nanotechnology, in which high-performance devices and materials are manufactured at the minuscule size of atoms and molecules. Little did she know this would lead to a medical breakthrough. At Cal’s Nano-Biology Lab, Sohn, 39, has found a way to put a suite of medical diagnostic equipment on a disposable chip smaller and cheaper than a nickel.

Her inspiration came from studying cells’ protein pores, which are sensitive to the structure of individual ions: each type of ion that the cell needs to survive flows through a specialized pore. By creating a chip with nano-scale pores sensitive to individual diseases, Sohn realized, she could sift through a patient’s blood and perform diagnoses normally requiring extensive testing.

Using the high-precision process of microchip manufacturers, Sohn etched a negative impression of the pore for a specific molecule into a slab of glass. Then she molded individual pores in quantity by pressing dabs of wet silicone rubber against her glass mold. She laid two platinum electrodes across each rubber pore and ran a current through that would fluctuate if a molecule entered the cavity. Because the pore was molded to admit only a specific kind of molecule, she demonstrated that her nanopore could detect the molecular signature of a disease.

When the U.S. Army showed interest in her research, Sohn built a simple electronic circuit with a nanopore that could detect in just a pinprick of blood the antibodies produced by exposure to anthrax. The army is testing the device now.

A couple of years ago, a college friend, now studying leukemia, saw another application. “We were talking about our work over lunch at Chez Panisse,” Sohn recalls. “During that conversation, the nanocytometer was born.”

Still in prototype, the nanocytometer is a handheld electronic device with a replaceable rubber, micron-scale pore. Beyond detecting cells associated with bloodborne cancers such as leukemia, thus warning of impending metastasis, it can capture those cells as they pass through the nanopore, allowing the device to store them undamaged for culturing. Experimental therapies can then be attempted in a petri dish, without risk to the patient.

Mark said...

INVENTION 4
A much cheaper cure

WHAT IT IS: A genetically modified yeast that produces malaria medication cheaply and abundantly

LEAD INVENTOR: Synthetic biologist Jay Keasling, Lawrence Berkeley National Laboratory

FANTASY APP: Manipulating the DNA of yeasts and bacteria to produce medication for a host of terrible diseases, including those spread through biochemical agents

THE STORY: Farmed from the sweet wormwood tree, the drug artemisinin has been used for decades to cure malaria. But the cost of extracting the drug from the trees, whose numbers are diminishing, keeps the price at $2.40 a dose, meaning that the majority of those who contract malaria—children in developing countries—can least afford treatment. Keasling had a solution: why not simply transfer the drug-producing genes to a lower-maintenance organism like yeast? Synthetic biology, the next generation of genetic engineering, gave him the means of building a novel organism by stripping genes from one species and adding them to another. With a $42.6 million research grant from the Bill and Melinda Gates Foundation, Keasling has given strains of yeast new life as a cheap pharmaceutical source. He’s working to reduce the price of an antimalaria drug to 25 cents a dose.

Mark said...

Fish can fight malaria mosquitoes

The fish consume the mosquito larvae

BBC Reports:

Kenyan researchers have hailed a humble fish as the latest weapon in the battle to curb the spread of malaria.

Nile tilapia, a fish more usually seen on Kenyan dinner tables, was introduced to several abandoned fishponds in the west of the country.

By consuming mosquito larvae it managed to reduce numbers of two of the main malarial mosquitoes by more than 94%.

The BMC Public Health study noted the fish could prove critical as mosquitoes are becoming resistant to pesticides.

Nile tilapia's taste for mosquitoes has been known since 1917 but this is the first time field data has been published detailing their use in mosquito control, the researchers from the International Centre of Insect Physiology and Ecology said.

Every 30 seconds

Malaria, spread by the single-celled parasite Plasmodium, is endemic in parts of Asia, Africa, and central and south America.


This method may well work in a defined area of water, but mosquitoes spread in all sorts of places - including small pools in the mud and puddles - where you obviously can't introduce fish
Joanne Greenfield
WHO

The organism is passed to humans through the bite of a mosquito. Each year it makes 300 million people ill and causes a million deaths worldwide.

Some 90% of cases are in sub-Saharan Africa, where a child dies of malaria every 30 seconds.

The authors suggested that for Kenyans, the fish could prove a win-win investment. In addition to limiting mosquito populations they could also be used for food, and even generate income, too.

Joanne Greenfield, malaria advisor for the World Health Organization in Kenya, was more circumspect, while describing the findings as "positive".

"This method may well work in a defined area of water, but mosquitoes spread in all sorts of places - including small pools in the mud and puddles - where you obviously can't introduce fish," she said. "It just wouldn't work for many areas."

But she added: "We recommend a spectrum of methods to combat malaria, and this could certainly be a useful tool."

http://news.bbc.co.uk/2/hi/health/6937270.stm

Mark said...

Medicine, Healing Harmonics, and Music
(originally posted as a comment here)

Some comments about 'pure tones' and current music, which I think more should know about if you start to seriously get into cymatics issues and vibration issues in health or strange physics effects--which fit into the presumed "Philadelphia Experiment, to the Hutchinson (harmonics) Effects, to Cold Fusion high frequency effects, to presumed crop circle diatonic scales being used in many of them in the physical ratios of the patterns, to various interesting cymatic frequency healing devices, to Qigong practitioner's hands emitting secondary sound waves they have found out that, when recorded and played back to hospital patients, heal faster (more on that below), etc. The healing (audial) touch?

The "Music and Harmonics" section above talked of notes fitting harmonically into an 8-note scale and passed over that this is actually unnatural for the harmonics that the human body and mind tend to recognize as harmonic and pretty: fifths.

It's only fifths that are actually strangely human-mind felt harmonic and pretty (no one really can explain why), while octaves are just the same frequency doubled, without the various reverberatory tones of consonant notes like fifths (or thirds, fourths). Though it's fifths that humans tend to note as the prettiest, the world round.

However, most music (and fifths) you will hear nowadays will always be tuned flat from instruments. Every note.

Why?

That's what this long quote is about, from a book.

How intentionally flat tunings became known as "well-tempered" is the point of this. "Well-tempered" tends to on the surface imply harmony, though perversely it's nothing like that. It is equal, though it's all flatted notes and subtly outside of harmonic resonance, particularly for fifths.

Our admixture of odd tunings popularized by the West from the early 1700s has an interesting history. Europe started to popularize non-harmonic scales subtly out of whack, for intentionally creating flat notes equally flatted to squeeze in fifths into octaves, to avoid retuning an instrument when you wanted to change keys.

However, the idea of 'equal flatting' of fifths to fit them into octaves series was actually a Chinese inventor's idea in the 1580s: to put two different disharmonic scales (octaves, based on 2x the previous note; and fifths, based on 1.5x the previous note, that never really match anywhere) artificially together into the same instruments by 'flatting all fifths' over a scale of 12 notes equally, to scrunch and make the octave series the basis for the flatted fifths--which it is the fifths that are the most human-healing oriented and pretty.

The "tempering" allowed for transposings between octaves and keys. Got that? No. :-)

Well, I copied (really, spoke into some text to speech software) to clarify from a book I have on Chinese science history, in its interesting chapter on music.

When Bach wrote his "well tempered clavichord" it is generally unappreciated that he was actually writing a musical manifesto of this different transpositional and intentionally flat tunings. He wanted to popularize this flatted tuning, and demoting previous different harmonics based tunings in Europe and and it turns out, worldwide. The implication of Bach's publication of 1722 flatted Well-Tempered Clavier series has been very profound.

(Perhaps this is why I've always enjoyed "pre-Bach" music: of the 1600s with different tunings on ancient instruments more than other 'modern' 'post-Bach' European music. There's something about Bach that has always just made me feel angry like it was harmonically wrong or something. Grating. :-)

However, the odd thing is that Bach was drawing his ideas about equal tempering from a Chinese musical theorist of the 1580s.

Anyone who gets into 'pre-modern' tunings and scales or actual pure harmonics is going to run into both Egyptian (pyramids) issues and Chinese issues of their harmonic scales and their 2,000 year old bells.

Forgive the quote's length. It's just three pages in a book. Skip over it if you are not interested-- though if you follow anything from above or the last post, 'real harmonics' are key to a lot of different things discussed here at RI.

The quote is from The Genius of China: 3,000 Years of Science, Discovery and Invention, by Robert Temple (1989), 206-213:

"

The first understanding of musical timbre. Third century A.D.

We have already mentioned timbre. It is sometimes called the "quality" of a musical notes. It may be defined as the original fundamental note sounded, together with the overtones present with it. A tuning-fork casts no timbre, because it merely sounds of the fundamental note free of overtones; but the rich and resonant sounds [caused by sympathetic vibrations in other non-played strings that sound when you play 'one' note on the piano, since the sound itself starts to 'play' any other sympathetic frequencies on other strings automatically through the air] produced by a modern piano are a triumph of the art of production of harmonious timbre.

The only sources of harmonious [automatically adjusting] timbre possible in non-electronic musical instruments are vibrating strings [in pianos] and [sympathetic] vibrating columns of air (as in pipes or flutes).

Bells can be acceptably harmonious in their timbre [particularly ancient Chinese bells, see below, that actually were cast to play fifths and thirds harmonically--which no one can still do today, a lost art how they designed their 3,000 year old bells], but percussion instruments have bad timbre.

The Chinese achieved a deep and profound understanding of timbre [sympathetic resonance], and went further than any other culture, before or since, in exploiting it for musical purposes.

The ancient Chinese zither known as the ku ch'in, or just simply ch'in (sometimes called the classical Chinese lute, although it is in reality a halftone zither, usually of seven strings but originally a five and occasionally of nine) is, as Needham tells us, "the only musical instrument in any culture which has no frets and actually marks the nodes of vibration on the board."

The very fact that there can be such a thing as a stringed instrument with no frets seems astonishing in itself.

The point of this instrument was that the strings were not played in such a way as to ever change their pitch, as happens when a string is pressed on to a fret in other instruments, such as the guitar or the violin. The ch'in was played with each string remaining at the same pitch at all times, and the art of playing was the production of different timbres of each string at a constant pitch.

This is so subtle that many Westerners might balk and question whether the result would strictly be music at all. But it is in fact a wonderfully rich and satisfying music.

The strings of the ch'in are all of silk. The traditional manner of playing them involve more than 26 different "touches" or means of plucking or stroking them, for vibrato alone....The playing of the ch'in obviously require a musical notation different from usual.

Musical notation for this instrument took the form of instructions, not only on which strings were to be used, note by note, but on the "touch" by which the fingers were to play each note.

Many piece of music for this instrument also survived which additionally indicates that the rising or falling intonation of the words [similar to different tones for the same word sounds in the Chinese language can mean different words] sung by the singer were to be accompanied by the zither; the change in voice intonation was matched by the variations in timbre of the instrument -- a particularly subtle musical technique [shadowing the Chinese sung language perfectly].


Equal temperament in music; 16th century A.D.

The inventor of equal temperament and music was Chu Tsai-Yu, who published his invention in 1584. The first mention of his invention was in the unpublished papers of the great mathematician Simon Stevin (died 1620). Chu Tsai-Yu was born in 1536, a prince of the Ming Dynasty.

But he turned his back on his princely rank and concentrated instead on studying music, mathematics and the science of the calendar.

This system of equal temperament appeared in his book A New Account of the Science of the Pitch-Pipes, published in 1584. The Chinese did not pay much attention to the new system, but the Europeans quickly saw its advantages [mechanistically].

Two years earlier, the great Chinese scholar of the Jesuits, Matteo Ricci, commenced his studies at Macao. From 1580, the Viceroy of the Cantonese province [where Portuguese city-colony Macao was on the Chinese southern coast] had established biannual "trade fairs" lasting several weeks, at which Chinese and Westerners exchanged ideas and goods.

The interchange between East and West was intense, just at the moment when Chu Tsai-Yu went into print with his new theory. It is a case of perfect timing which gives one the feeling that it was "meant" to happen.

We do not know the exact mode of transmission of the idea to Europe; there can be no doubt that Western music was to be totally conquered by the Ming prince, for within 52 years of Chu's publication, his ideas were published by Pere Marin Mersenne.

The Ming ended eight years later, but Ming music today blares from every transistor radio in the world.

The first published reference to the mathematical basis for equal temperament in Europe, was by Mersenne in one of his many books of musical theory, entitled Harmonie Universelle, issued in 1636. Werkmeister later popularized equal temperament, and Johann Sebastian Bach took up the cudgels on its behalf by composing a series of pieces, collectively entitled The Well-Tempered Clavier, consisting of "preludes and fugues in all the tones and semitones... for the use and practice of young musicians who desire to learn, as well as by way of amusement, for those who are already skilled in this study."

This epochal work was published in 1722. Yet probably only a few of all those who have ever listened to or play these pieces have had any idea of Bach's underlying intentions. The Well-Tempered Clavier was a work of propaganda [and like much coldly thought out purposes of propaganda makes "bad emotional art", though that is just my opinion as a Tartini (1692-1770) lover [<-- listen] and von Biber (1644-1704) lover [<-- listen] instead of a Bach lover].

Bach (1685-1750) had adopted equal temperament with a passion later to be matched by that of his fellow-composer Giuseppe Tartini's opposition to it [whom I've always preferred].

Equal temperament allows one to modulate fluently from key to key consecutively in the composition and performance of music [without retuning].

It was passionately adopted by those who thought the practical advantages of this were paramount [or those who were lazy and emotionally tone deaf] and was as passionately opposed by those who thought that purity of tone and other substantial factor should not be sacrificed to such base utility.

These frenzied debates and disagreements have died down now in the West, at least for the moment. [However, if there's healing in only pure harmonics of frequencies or even Hutchinson-like or 'cold fusion'-like alchemy, or in medical practices, the concern for pure harmonics may be set alight once more in music through equal sympathetic vibration; see my conclusion to this quote].

Equal temperament, so hugely aided by the prestige [and manic coffee impatience/addiction] of Bach, triumphed utterly during the 19th century, yet many of today's musical experts do not really understand its principles, and no more than a handful of Westerners can now appreciate what music would sound like without it.

[Except you reading this perhaps, right now.]

The only way for the reader to appreciate the magnitude of the subject is for us to consider the underlying problem which makes perfection of tone in all music composition impossible. It is one of the most fascinating but least known of the fundamental enigmas of the Universe. There is no music conceivable, on what ever planet, in whatever galaxy, where the dilemma could be escaped.

Let us illustrate the manner in a simple way by discussing a piano.

Most people know that a note struck simultaneously with a note 8 notes higher (in a scale) is an "octave". The low note and the high note are the same (say a C), except that the high note is 'C an octave higher than the lower C'. The higher one is double the frequency of the lower one. [Middle C is around 264 Hz, or vibrations per second.] This is true whatever note played; an octave is defined as a note of a particular frequency sound with a note of twice that frequency. Octaves are quite simple. They also rather boring, because the same notes sounded an octave apart have no variety. There is neither consonance or dissonance; there is just uniformity. An octave is like a man standing and staring at a photograph of himself which he holds in his hand: a simple double image.

How much more interesting it would be if the man were to stand with his arm around a woman whom he loves, or were to be scowling at one whom he hates. The first would be a consonance and the second would be a dissonance. The interest of life is in its variety and juxtaposition; hence, a C played with any other note than another C takes on greater interest to us than the octave.

The most pleasing consonance of two notes sounded together is what is called a "fifth". This is not simply subjective; an analysis of the sound waves involved shows that the higher harmonics of the notes have consonant beats with one another. But there does remain a mystery about the preference human beings find for harmony and the annoyance they experience upon hearing dissonance. Sir James Jeans has written: "it must be admitted, however, that [there] is a defect of most theories of discord. Innumerable theories are ready to tell us the origin of the annoyance we feel on hearing a discord, but none even attempts to tell us of the origin of the pleasure we feel on hearing harmony; indeed, ridiculous though it may seem, this latter remains one of the unsolved problems of music."

What, then, is this most pleasing and harmonic of all sounds, the fifth?

For it was the fifth rather than the octave which was the basis for Chinese music. [Actually if you struck a Chinese bronze bell it would sound a fifth harmonic actually, or a third harmonic, instead of a 'note'. This has only been found out actually in the past 10 years, that the Chinese knew how to cast predictable HARMONIC multitone bells 3,000 years ago, which Europe couldn't even do until this century:

"Archeological sensation
The 65 bronze bells from the tomb of Marquis Yi of Zeng (433 B.C.) are considered as one of the most fortunate discoveries in archeology. Due to favorable conditions of tomb preparation, soil, and soon natural water filling, the bronze of the bells survived fully intact. The bells sound as they did 2,436 years ago, and - as yet - better than any replicas that have been made in our days.

Two tones per bell

Two-tone bells were common in China between 1200 and 200 B.C. After that the advanced know-how to cast them was lost, and it could not yet be fully recovered in our days.

The bells have an eye-shaped cross-section and vibrate in one of two modes, depending on where they are struck.

A strike in the middle of the front makes frontside and backside vibrate as whole units and produces the lower tone sui.

A strike between the middle of the front and a side edge makes frontside and backside vibrate as two units each and produces the higher tone gu.

If struck correctly, both tones are fully independent, each with its own fundamental and harmonics. This is shown in a spectral analysis, presented together with the underlying sound samples, of the two tones of one of the original bells.

Quality and timbre of the two tones are fully compatible, and they are both marked by tone-name inscriptions on the bells.

Thus, both were intended to be used in musical practice.

Of the 33 bells in the melody section of the Zeng ensemble, 21 have a sui-gu interval of a minor third (mean 312.4 Cent, SD 13.8), 10 have one of a major third (mean 403.1 Cent, SD 18.1), and two have apparently mistuned ones with 244 and 342 Cent (details below).

Tone name system

The tone names inscribed on the bells very clearly reflect a theory of scale generation by both fifths and thirds. It must be examined, however, if the actual tuning practice agrees with the theory. The results show that it does not. The tone name system obviously had lost its theoretical background for the bell casters (details [not] below). But it is a very interesting name system, because it shows an awareness of the thirds in the concept of scale construction, something that developed in Europe [only] ca. 2000 years later."

http://web.telia.com/~u57011259/Zengbells.htm

That website may have a hardwired answer to why fifths and harmonics sound 'right' to the human brain, as well as why vowels in languages sound pretty: they are mostly the same harmonics and processed in the same way by the brain.

"

Pitch and harmony detection in the auditory midbrain

Before 1998 it was unknown that the unique neural map of acoustic frequency in the auditory midbrain (inferior colliculus) is a functional adaptation for pitch extraction from complex tones.

The vocalization sounds of many mammalian species and the vowels of human speech consist of a series of harmonics (e.g. 900 Hz, 1200 Hz, and 1500 Hz).

[All meditation mantras I've ever heard are full of sonorous vowels, hitting thus harmonics in the brain and body.]

They are unified in the auditory brain of these animals into a single percept of one pitch (an equivalent of 300 Hz in the given example).

This spectral synthesis supports the localization and the identification of single sound sources in natural, noisy environments.

The auditory midbrain is adapted to this task by its anatomy of stacked neuronal layers. Each layer processes sound signals from a specific bandwidth of the acoustical spectrum, and the separation into bands is optimal for the neuronal combination of harmonics that is needed for pitch extraction.

Because the auditory midbrain is hardwired for the processing of low-order harmonics in vocalization sounds, it is also hardwired for the processing of harmonic spectral components in music.

The mechanism that provides pitch detection in speech does the same job in music as well.

Our brain prefers harmonic tones and harmonic tone combinations, because it can extract more information from them [and because it 'makes the brain glow' more, as it hits different 'stacked neuronal layers' in their phrase simultaneously.]

Back to Temple:

"

A typical example would be the chord CG. Then if you play successive fifths, using a top note of one fifth as the bottom note of a new fifth, you do not come to a C again for quite some time...In fact, you have a succession of 12 fifths, before reaching another.

Musical theorists like to speak of the ascending fifths as a "spiral of fifths", and they draw them in a diagram spiraling upwards.

If you count the number of octaves between the first and last note in a spiral of 12 fifths, you'll find that there are seven. As the spiral has gone round, it has repeatedly missed the higher octave notes of the original note, [making eighths and fifths without any 'real' harmonic connection at all] until finally after 12 fifths it hits the seventh octave of the original note. [So they say...] Then and only then [i.e., only the distance of seven octaves actually has a somewhat harmonic resonance with the fifths] do the two separate ascending series, meet.

And upward (or downward) spiral of fifths and an upward (or downward) spiral of octaves thus only me up when 12 fifths and seven octaves end on the same note. Until then, on their upward or downward courses, the two means of proceeding had been quite separate. It is as if two runners were running the same distance on two separate tracks which went over and under one another repeatedly until they reach the same finishing post, at a point where the separate tracks met for the first time since the start.

This is important, for upon examining this more closely we find that it is not as simple as it seems -- there is something curiously wrong.

The problem is this: musical tones are very precisely measurable in the laboratory, and an exact number is assigned to every note as its frequency. Now, when one plays a C seven octaves higher than another C, we find that its frequency is 128 times that of the original. (Every octave doubles the frequency, and if you progressively double something seven times you have in fact made it 128 times its original self). But if you want to have a sequence of fifths [12 times over, here's the paradox, which of course are exactly close to the same note] which increased by 1.5 times the original frequency (which is what fifths do) 12 times over, you will achieve a final result not exactly equal to the 128 of seven octaves [2^7 = 128x], but equal instead to the slightly different amount of 129.75, which is the value of (1.5)^12 [=129.75x].

The fact is that the mathematics of the fifth is incommensurable (harmonically) with the mathematics of the octave [despite current piano tuners claims to the contrary, or even piano builders].

A note which is a fifth higher than another note has a measurable frequency 1 1/2 times that of the lower note.

And [duh] the number 1.5 is arithmetically incommensurable with the number two (which expresses the doubling of the frequency of a note when raised an octave). So the fifth in the octave are out of joint with each other on fundamental arithmetical grounds.

The spiral of fifths comes to a stop at a point which is 1.0136 times the sequence of octaves. (Or, the frequency 129.75 is 1.0136th that of 128). This value, 1.0136, is known as "the comma of Pythagoras", after the Greek philosopher who discussed it [who supposedly learned everything from Egypt].

The different keys are established in Chinese music by the 12 different notes of the spiral of fifths [in other words the Chinese "octave" was based on a harmonic repeating of fifths not eighths, a comparatively huge 'octave,' so to speak, thinking about a piano, which means 12 fifths was one 'octave' to the Chinese], and these 12 notes are all found within the compass of a single fundamental octave. The spiral of fifths ascends from C to G to D to A to E to B to F sharp to C sharp to A flat to E flat to B flat to F back to C (except, as just mentioned, this C is not absolutely precise). It will be appreciated that all of these notes fall between one C and the higher or lower C, and give the 12 keys. These 12 notes also give the complete chromatic scale of modern music.

Equal temperament is an artificial system created to get round the fact that the spiral of fifths ends on a note that's slightly off the end of the sequence of octaves. The tiny fraction of 0.0136 is divided into 12 equal parts, and each part is subtracted from one of the 12 notes into which an octave [in Europe] is divided [i.e., the white and black piano keys]. This means that the gap between a note and its "fifth" is no longer precisely 1.5, but is instead a tiny fraction less, 1.4983.

This "violence" done to all the fifths squeezes them into the tinier space of a pure octave.

All 12 steps in the octave are now precisely equal [from each other, instead of related to harmonics], and are called semitones. In order to accomplish this, each fifth has been artificially but evenly rendered flat by about one 48th of a semitone.

All equally tempered music is thus uniformly and unremittingly "flat".

But it provides a regular and reliable structure so that one can modulate from [flat] key to [flat] key [quickly], for as much richness and variety of composition as one could desire.

This is not to say that much has not been lost -- sacrificed on the altar of utility. Our modern ears have been so debased by hearing only equally tempered music that we no longer know a pure tone. We send for a piano tuner to tune our piano, but in fact, he comes and tunes it flat, as relentlessly as ants march forth from their nest. We are thus subjected, from birth to death, to nothing but flat notes [in modern music scales].

We never so much as hear a pure tone [or, perhaps, know their healing power.]

Before equal temperament, in both China and the West, there were various "modes" of untempered music. For the sake of simplicity, we can speak as well of the ancient Greek ones, which have less difficult names, though they all have Chinese equivalents. There were the Ionian, Dorian, Phrygian, Lydian, Mixo-Lydian, Aeolian and Locrian modes. Instruments could be tuned to only one mode at a time. Some of the modes were happy and carefree, while others were sad and mournful. They represented a vast richness of emotional [and perhaps healing] intensity and experience which has now completely and utterly vanished from the music known to us today. It is impossible to describe them: the colorations and subtleties of the different modes were somewhat like the difference which we note between the major and minor keys, multiplied several times.

In the absence of these old modes, not a single person in the entire Western world unafflicted by deafness can avoid hearing at every turn, music fashioned [to flat notes] from an imported Chinese theory [into European mass produced instruments and music notation].

"/endquote

The book Civilization One (2006) has some interesting things to say about Chinese harmonics as well as Egyptian and Babylonian harmonics.

In short, Prince Chu Tsai-Yu invented equal temperament in music, and published the idea in 1584 in his New Account of the Science of the Pitch-Pipes. He proudly stated: "I have founded a new system [to intentionally flat all 1.5x based fifths equally, to fit 2x based octaves]." Little could he have realized that his system would be universally adopted in the West. Coffee-addled Johann Sebastian Bach was its leading promoter--or addict, you decide.

---

More purely created electronic harmonics are the basis of some interesting healing technologies invented in the past 30 years. Note the Qicong frequency generator as well1!

Cymatic Instruments in Sound Therapy

In Sound Therapy such devices are employed that utilize specific sound frequencies to achieve therapeutic benefits such as pain reduction or relaxation. Treatments from devices such as cymatic instruments and the Infratonic QGM today are being used worldwide.

The Infratonic QGM: The Machine That Produces Qi Energy

Lu Yan Fang, Ph.D., a senior scientist at the National Electro Acoustics Laboratory in Beijing, China, discovered that Qigong masters emitted from their hands high levels of waves called secondary sound. She constructed a machine that simulated this infratonic sound and tested it on over 1,100 hospitalized patients.

Numerous therapeutic benefits were noted, including pain reduction, headache relief, increased circulatory functioning, muscular relaxation, alleviation of depression, and increased brain production of alpha waves.

Her instrument, the Infratonic QGM, received awards of recognition from the China Ministry of Health and the National Committee for Traditional Chinese Medicine.

In China it is medically recognized as an effective pain management tool.

In the United States it is today pending FDA (Food and Drug Administration) approval for use as a therapeutic massage device.

Cymatic Therapy

Sir Peter Guy Manners, M.D., D.O., Ph.D., of Worcestershire, England, states that cymatic therapy is not applied through auditory channels, but directly through the skin.

Cymatic therapy uses sound waves within the audible range to stimulate natural regulatory and immunological systems, and to produce a near-optimum metabolic state for a particular cell or organ.

Dr. Manners says, every object, whether inanimate or alive, possesses a unique electromagnetic field that exhibits antagonistic, complimentary (resonant), or neutral reactions when it interacts with other electromagnetic fields.

Resonant equilibrium represents the healthy state (resonance may be defined as the frequency at which an object most naturally vibrates); illnesses is represented by resonant disequilibrium.

Cymatic therapy uses a computerized instrument to establish equilibrium in the body by transmitting resonant frequencies of sound into the body.

These signals pass through healthy tissues, but reestablish healthy resonance in unhealthy tissues.

Dr. Manners has researched the signals given out by healthy tissues [and utilized a particular Yale University researcher's previous work as well].

By intercepting [i.e., 'listening electronically to'] electrical messages transmitted via the central nervous system to individual cells, this research has allowed the [artificial] coding of cymatic signals that cells understand. [I think IC recently posted something about the nervous system running on sound waves, as much as electromagnetics, right?]

Each tissue has been given an H-factor (harmonic factor) according to the signal emitted.

The cymatic instrument adjusts acoustic audible sound frequencies in order to induce beneficial stimulation, activation [of what, DNA?], and circulation when applied to the body via direct contact with affected areas or by way of acupuncture meridians.

Cymatic therapy does not cure, but simply places the body in a situation so that it can cure itself without pain, surgery, or drugs.

Dr. Manners believes cymatic therapy for humans in the future will likely concentrate on the skin, peripheral nerves, and bone, since these are the areas capable of regeneration.

It may also be useful in organ transplantation, balancing the resonance of the transplanted organ with that of the recipient.

Cymatic instruments have been in use worldwide for over twenty-eight years, and have been in use in the United States since the late 1960s.

They are used by nurses, chiropractors, osteopaths, and acupuncturists throughout the world. Training is required to become a cymatic practitioner. Cymatic instruments produce no side effects, and the only contraindication for use is for patients with pacemakers.

[Here's a picture of one. Check the PDF on that page as well, for a list of particular coded "frequency symptoms correction chart". Here's a picture of a U.S. manufactured one, with the speaker unit that is held up to the body.]

The [electronic-audio based] Cymatic instrument, and (third) [electromagnetic, non-audio] Vibe Machine [<-- link, video interview with the inventor, Gene Koonce, 18 minutes] are three forms of electromagnetic/audio frequency healing technologies, based, basically, on what might be called music--and how different parts of our body vibrates either in sync with health or out of sync with ill health.

We’ve already gotten into DNA issues of frequency being activated (biophotonic light).

The Cymatic instrument is based on the physical fact that certain areas of the body have their own frequencies (a Yale University researcher did the basic research on this in the late 1960s and 1970s, which Sir Guy Peter Manners applied in his Cymatic instrument), and are ‘off’ in ill health.

I would theorize that the mechanism here is that righting different resonances in the body switches on DNA in special ways, just as the same way that audible chanting might do the same or singing, or music. (Though the Vibe Machine seems to give a jolt to the ATP cell energy manufacture, by correcting the body's intracellular frequency to allow the body to make ATP more efficiently, or at optimal health--which has according to some (currently anecdotal) even capacities to detoxify heavy metals from the body naturally when you are optimized. Gene Koonce is sort of a 21st century Raymond Royal Rife who isn't dead...and who has already mass produced his equipment and pollinated it around the world (thankfully), whereas Rife's machines were not mass manufactured and were soon killed off.

Make harmonics and make healing seems to be the recipe.

Mark said...

[However, most 'conventional' (i.e., toxic) farming uses a lot of pesticides on peanuts. If you can find non-pesticides versions then, this may be useful:...]

Boiled nuts help protect against illness, boiling preserves phytochemicals
Fri Oct 26, 3:45 PM ET

BIRMINGHAM, Ala. - For lovers of boiled peanuts, there's some good news from the health front. A new study by a group of Huntsville researchers found that boiled peanuts bring out up to four times more chemicals that help protect against disease than raw, dry or oil-roasted nuts.

Lloyd Walker, chair of Alabama A&M University's Department of Food and Animal Sciences who co-authored the study, said these phytochemicals have antioxidant qualities that protect cells against the risk of degenerative diseases, including cancers, diabetes and heart disease.

"Boiling is a better method of preparing peanuts in order to preserve these phytochemicals," Walker said.

The study will appear in Wednesday's edition of the American Chemical Society's Journal of Agricultural and Food Chemistry. The other co-authors in the study are A&M researchers Yvonne Chukwumah and Martha Verghese, as well as University of Alabama in Huntsville researcher Bernhard Vogler.

Walker said peanuts and other plants use phytochemicals for things such as helping avoid disease and insect attacks.

"These things are not nutrients; at the same time they have health benefits to humans," he told The Birmingham News. "The trick is to keep those health benefits, not to process them out of the foods."

According to Walker, water and heat penetrate the nuts, releasing beneficial chemicals to a certain point. Overcooking the nuts destroys the useful elements.

Alabama is third in the nation in the amount of peanuts produced with a crop valued at more than $67 million last year.

---
http://news.yahoo.com/s/ap/20071026/ap_on_he_me/boiled_peanuts

Phytochemicals as therapeutics

There is abundant evidence from epidemiological studies that the phytochemicals in fruits and vegetables can significantly reduce the risk of cancer, probably due to polyphenol antioxidant and anti-inflammatory effects.

Phytochemicals have been used as drugs for millennia. For example, Hippocrates in 400 BC used to prescribe willow tree leaves to abate fever. Salicin, with potent anti-inflammatory and pain-relieving properties, was originally extracted from the White Willow Tree and later synthetically produced to become the staple over the counter drug called Aspirin.

The number one drug for cancer worldwide Taxol (paclitaxel), is a phytochemical initially extracted and purified from the Pacific Yew Tree.

Among edible plants with health promoting phytochemicals, Diindolylmethane, from Brassica vegetables (broccoli, cauliflower, cabbage, kale, Brussels sprouts) is currently used as a treatment for Recurring Respiratory Papillomatosis tumors (caused by the Human Papilloma Virus), it is in Phase III clinical trials for Cervical Dysplasia (a precancerous condition caused by the Human Papilloma Virus) and is in clinical trials sponsored by the National Cancer Institute of the United States for a variety of cancers (breast, prostate, lung, colon, and cervical). The compound has potent anti-viral, anti-bacterial and anti-cancer properties through a variety of pathways and it has also been shown to synergize with Taxol in its anti-cancer properties, making it potentially a very important anti-cancer phytonutrient as taxol resistance is a major problem for cancer patients worldwide.

Sometimes some of the compounds in plants with potent medicinal properties may not necessarily be chemicals, but may be elements, such as selenium found abundantly in Brassica vegetables with potent anti-viral and anti-cancer properties.... It has also been shown to reduce mortality among prostate cancer patients.

There are currently many other phytochemicals with potent medicinal properties that are in clinical trials for a variety of diseases.

Lycopene, for example, from tomatoes is in clinical trials for cardiovascular diseases and prostate cancer. Human clinical trials have demonstrated that lycopene helps to improve blood flow through the heart and clinical studies suggest anti-cancer activity against prostate cancer.

Lutein and zeaxanthin from spinach have been shown through clinical trials to directly improve human visual performance and help prevent the onset of macular degeneration and cataracts.

In a landmark nutritional sciences study, scientists demonstrated that a diet rich in tomotoes and broccoli was more effective in inhibiting prostate cancer growth than a leading drug for prostate cancer.

...

Clinical investigations are ongoing worldwide on thousands of phytochemicals with medicinal properties.


Food processing and phytochemicals
Phytochemicals in freshly harvested plant foods may be destroyed or removed by modern processing techniques, possibly including cooking
[2][3].

For this reason, industrially processed foods likely contain fewer phytochemicals and may thus be less beneficial than unprocessed foods.

Absence or deficiency of phytochemicals in processed foods is believed to have contributed to the increased prevalence of the above-cited preventable or treatable causes of death in contemporary society.

...


List of foods high in phytonutrients

This article needs additional citations for verification.

Please help improve this article by adding reliable references.

Unsourced material may be challenged and removed. (July 2007)

Foods high in phytonutrients, or superfoods[4], are:


The top 10 phytonutrient rich foods
soy – protease inhibitors, beta sitosterol, saponins, phytic acid, isoflavones [though soy is mostly bad, actually]

tomato – lycopene, beta carotene, vitamin C

broccoli – vitamin C, 3,3'-Diindolylmethane, sulphoraphane, lignans, selenium

garlic – thiosulphonates, limonene, quercitin

flax seeds – lignans

citrus fruits – monoterpenes, coumarin, cryptoxanthin, vitamin C, ferulic acid, oxalic acid

blueberries – tannic acid, lignans, anthocyanins

sweet potatoes – beta carotene

chilli peppers – capsaicin

legumes: beans, peas, lentils – omega fatty acids, saponins, catechins, quercitin, lutein, lignans


Other foods rich in phytonutrients or superfoods

Some animal derived foods are also considered superfoods. Beginning in 2005, there has been a rapidly growing recognition of several common and exotic fruits recognized for their nutrient richness and antioxidant qualities, with over 900 new product introductions worldwide[5]. More than a dozen industry publications on functional foods and beverages have referred to various exotic or antioxidant species as superfruits (see References[5]), some of which are shown in the list below.

Apples – quercetin, catechins, tartaric acid

Açaí berries – dietary fiber, anthocyanins, omega-3, omega-6, Beta-sitosterol. Açaí is the highest scoring plant food (spices excepted) for antioxidant ORAC value[6]

Dried apricots

Artichoke – silymarin, caffeic acid, ferulic acid

Brassicates: kale, cabbage, brussels sprouts, cauliflower – lutein

Carrots – beta-carotene

Cocoa – flavonoids, epicatechin

Cranberries – ellagic acid, anthocyanins

Eggplant

Gac – beta-carotene, lycopene

Goji (Wolfberry) - ellagic acid, β-carotene, β-cryptoxanthin, zeaxanthin, lutein, lycopene

Pink grapefruit – lycopene [MOST grapefruits absorb lots of pesticides however, read about it]

Red grapes and wine – quercitin, resveratrol, catechins, ellagic acid

Green tea – quercitin, catechins, oxalic acid

Mangos – cryptoxanthin

Mangosteen - xanthones

Nuts and seeds – resveratrol, phytic acid, phytosterols, protease inhibitors
Porridge oats soluble fibre magnesium, zinc

Okra -- beta carotene, lutein, zeaxanthin

Olive oil – Monounsaturated fat

Onions – quercitin, thiosulphonates

Papaya – cryptoxanthin

Bell peppers – Beta-carotene, vitamin C

Pomegranate - Vitamin C, Tannins, especially Punicalagins

Pumpkin – lignans, carotenes

Quinoa - Dietary fiber, protein without gluten with balanced essential amino acids

Sesame - Lignans

Shiitake mushrooms

Spinach – oxalic acid, lutein, zeaxanthin

Squash

Watermelon – lycopene zeaxanthin, sulphoraphane, indole-3-carbinol
Low fat yoghurt calcium

Spirulina - beta-carotene


See also

Phytochemistry
List of phytochemicals and foods they are prominent in
Secondary metabolites

...

External links
Phytochemical Database - United States Department of Agriculture
Phytochemicals - Overview of phytochemicals with structures and properties.
Phytochemicals as Nutraceuticals
Phytochemicals at LPI - Linus Pauling Institute at Oregon State University
Phytochemical discussions in the Natural Products Discussion Group - sponsored by Herbal Sciences International
Retrieved from "http://en.wikipedia.org/wiki/Phytochemical"

---
http://en.wikipedia.org/wiki/Phytochemicals

[Caveat wiki-emptor]

Mark said...

[Strictly from a material point of view, this would go a long way to explain the psychological healing aspects and effects of historical shamanist ceremonies over the sick as interrupting the psychological conflict aspects in the victim's body and allowing the body to move toward its own healing.]

A New View of Cancer -- German New Medicine

German New Medicine (GNM), developed by Dr. Ryke Geerd Hamer, M.D., operates under the premise that every disease, including cancer, originates from an unexpected shock experience.

The discovery came after Dr. Hamer, the former head internist in the oncology clinic at the University of Munich, Germany, lost his son in an unexpected tragedy, then developed testicular cancer. The diagnosis led him to study the connection between stressful events and disease by investigating the histories of his cancer patients.

He found that, like himself, every one of his patients had gone through a very stressful episode prior to developing cancer, and, upon investigating other diseases found that every disease is controlled from its own specific area in the brain and linked to a very particular, identifiable, “conflict shock.”

GNM is based of five biological laws that apply scientifically to each and every case of disease.

They include:

#1: Every disease is caused by a conflict shock that catches an individual completely off guard.

#2: Provided there is a resolution of the conflict, every disease proceeds in two phases, a conflict-active phase and a healing phase.

#3: Ties the findings of the first two laws into the context of embryology and the evolution of man. It illustrates the biological correlation between the psyche, the brain, and the organ from an evolutionary point of view.

#4: Addresses the role of microbes in the context of evolution and in relation to the three germ layers from which our organs originate. Microbes are indispensable to your survival.

#5: Every so-called disease has to be understood as a “meaningful special biological program of nature” created to solve an unexpected biological conflict. Further, Dr. Hamer believes that a person cannot die of cancer in and of itself.

If someone dies during the conflict-active phase of disease, he says, it’s because of energy loss, weight loss, sleep deprivation, and emotional and mental exhaustion. The stress of receiving a cancer diagnosis, or being given a negative prognosis, is often enough to deprive a person of their life-force.

Conventional cancer treatments only accelerate the downward spiral.

If a patient has not undergone any conventional treatments such as chemotherapy or radiotherapy, GNM has a success rate of 95 percent to 98 percent.

While trying to publicize his findings, Dr. Hamer has been persecuted and harassed by German and French authorities. He is now living in exile in Spain where he is continuing his fight for official recognition of GNM.

German New Medicine (pdf)
http://germannewmedicine.ca/documents/Explore%20GNM%20Website%20Update.pdf

German New Medicine Home Page
http://germannewmedicine.ca/documents/welcome.html


---
http://articles.mercola.com/sites/articles/archive/2007/08/21/a-new-view-of-cancer-german-new-medicine.aspx#commentfocus

Mark said...

Japanese Doctor Finds Health With Metabolic Typing

Dr. Mercola's Comment:
Many people are confused as to what type of diet is the "healthy one." While there are some dietary principles that would benefit the majority of people, such as eliminating grains and sugar, the truth is that no one diet is right for every person.

If you are already feeling good, eating should, at the very least, help to maintain your energy level. But if you feel worse in some way an hour or so after eating, such as:

You still feel hungry even though you are physically full
You develop a sweet craving
Your energy level drops
You feel hyper, nervous, angry or irritable
You feel depressed
... then it might be due to an improper combination of proteins, fats and carbohydrates at your last meal. You might be eating the perfect foods for your metabolism, but having too much of one type of food in place of another can easily produce the symptoms listed above.

Many people come to my office eating very high-quality nutritious foods and are still quite sick. They haven't touched sugar or junk food in ages and still suffer with many health problems. There are a number of reasons for this, but one of the major physical ones is related to the fact that they are not eating appropriate foods for their Metabolic Type.

If you haven't yet read the book The Metabolic Typing Diet I would strongly encourage you to do so as it reviews these topics extensively. The story that follows was contributed by a doctor in Japan who wrote to William Wolcott (the author of "The Metabolic Typing Diet") to tell him about his success with Metabolic Typing. When you read his story, you will get a feel for the significant impact this method can have on health.


--------------------------------------------------------------------------------

Dear William Wolcott,

I greatly appreciate your book "The Metabolic Typing Diet."

I am a Japanese medical doctor who, five years ago, succumbed to illness of a flu infection, and I could not work for one year due to my poor physical condition. Before that, I had been aggressively working as a chest surgeon (I work as a primary doctor at the present.).

I have experienced trauma and have been afflicted by tinnitus, anorexia, headache,
urinary disturbance and other various autonomic imbalances for a long time.

At that time I was disappointed in modern medicine, but I had hopes for oriental medicine and I knew of diet therapies like macrobiotics.

Soon, I got started on the macrobiotic diet. I stopped all animal foods and dairy products. In 1999, I consulted Michio Kushi [one of the founders of macrobiotics] when he visited to Japan. He was gentle and advised me sincerely. In 2000, I visited the Kushi Institute [a well-known macrobiotic educational center] for three months because I wanted to study macrobiotics and know the real situation of macrobiotics in Americans.

Frankly speaking, I was discouraged. People who stuck closely to macrobiotics were barebones, not healthy and looked ghost. They were always irritated. Some teachers were nice and were good advisers, however almost all macrobiotic women had hard personalities and were not calm. On the other hand, almost all macrobiotic men were feminine.

Why? Macrobiotic people do not eat animal foods--they eat grains and vegetables.

In Japan there is a similar phenomenon. People who stick to George Ohsawa-style diet [a macrobiotic-type diet] are thin, aging and not calm. Most of his successors were not long-lived.

After flying back to Japan, I adhered to macrobiotics consistently because I believed that "Yan repels Yan," so Yan human should not eat Yan animal foods.

(Certain Japanese brown rice-diet authorities affirm that eating animal food is against the universe law, so if you eat animal food, you are sure to end your life.)

However, I began to feel sick when I ate much more brown rice. So, I ate
more vegetables. After doing this, my brain became sharp unlike before, but I could not gain strength. I got tired easily; I always felt hungry and my body became rigid.

All this time, I had repeatedly asked myself a great question: whether humans
should eat animal foods.

One month ago, I learned of your book through Dr. Joseph Mercola's Web site. Soon I read "The Metabolic Typing Diet" and learned that I am a "Protein Type" right on.

At last I figured out the mystery.

Now I know why certain people feel refreshed when eating brown rice, but certain people do not.

I learned that I should consume animal protein and fat. No, I MUST consume them.

Lastly, I abandoned being a so-called macrobiotic vegetarian and started eating fish and eggs and taking flaxseed oil.

The transitional period was short, and I now feel refreshed. I have no doubt that I was lacking protein and fat.

I appreciate knowing www.mercola.com and "The Metabolic Typing Diet." I am not yet in perfect condition, but I am relieved from anxiety and distress. I believe that I will return to health increasingly.

Japanese have eaten animal foods from ancient days. People living on the seacoast have eaten oceanic fish, shellfish and seaweed; people living in the mountains have eaten wild game and freshwater fish. Naturally they have eaten various grains and seasonal vegetables, and the Japanese have been active and sharp.

However, Japan has been westernized, and therefore we have forgotten our traditional diet.

Nowadays, poor-quality animal foods and vegetables, processed foods and junk
foods penetrate down to the streets. Almost all fish are contaminated, and there are few organic animal foods. [SOME ARE BISON AND OSTRICH.] Many Japanese people are sick, and there are a lot of crimes--absolutely regrettable.

Now is the time to recover a proper diet in Japan, but most Japanese physicians play down the role of diet in health. In the future, Japanese physicians must study the relationship between diet and disease.

Sincerely,

Yasumasa Takeda, MD
Chiba, Japan


---
http://www.mercola.com/2003/sep/6/metabolic_typing.htm


The Metabolic Typing Diet: Customize Your Diet to Your Own Unique Body Chemistry (Paperback)
by William Linz Wolcott (Author), Trish Fahey (Author)
http://www.amazon.com/exec/obidos/ASIN/0767905644/optimalwellnessc

People are unique in more ways than we can see. Stomachs and other internal organs come in many different shapes and sizes.

Digestive juices, too, can vary dramatically from one person to another. Thus, according to author William Linz Wolcott, founder of Healthexcel, a company that provides metabolic typing for individuals, it stands to reason that different foods have very different effects on different people.

Wolcott believes that tailoring your diet to your body's particular quirks--metabolic typing--will improve digestion, circulation, immunity, energy, and mood. To determine your type, he has you take a 65-question test (the questions range from nose moisture to how you feel about potatoes), then place yourself in one of three categories: protein type, carbo type, or mixed type.

The protein type is instructed to eat a diet that's 40 percent protein, 30 percent fat, and 30 percent carbs.

The carbo type gets 60 percent carbs, 25 percent protein, and 15 percent fat.

And the mixed type should consume 50 percent carbs, 30 percent protein, and 20 percent fat, although this type has to play with the ratios a little more to find the optimal mix.

Although The Metabolic Typing Diet is based on information from researchers the majority of the public will never have heard of, Wolcott makes a strong case that it's all based on common sense: most of the dietary problems we have come from ignoring the foods that make us feel satisfied and energetic in favor of ones that we feel we're supposed to eat, or foods that we eat in desperation because our last meal left us hungry or lethargic. If we just eat the foods that make us feel right, Wolcott argues, we'll never feel like things have gone horribly wrong. --Lou Schuler --This text refers to an out of print or unavailable edition of this title.

Review

"Metabolic typing is a huge step forward in the field of diet and nutrition, and this book is essential for anyone interested in optimizing their health by exploring their own biochemical individuality."
--Sherry Rogers, M.D., author of Wellness Against All Odds

heart of maui said...

Aloha Mark,

Blessings for offering this important information to the world at large. I have shared a number of excerpts with those who will truly appreciate them. I work with an elderly population that are being poisoned by the drug industry at great profit and ironically loss of health and well being to the client or 'consumer'.

My reason for connecting with this blog was to find out more about Richettsia and use of witch hazel as was indicated in a google search. A friend living is South Africa was recently affected.

I was not able to find the information and was wondering if you would kindly direct me to that a little more specifically.

Intuitively I am being told to also ask about effectiveness of using WAVE with same condition . My awareness is that she does have access to that technology. Names of any physicians or treatment centers you may feel would benefit her would also be appreciated. I think she is near Pretoria. Mahalos for your answer in advance.

Malama Pono )'( Skye

Mark said...

Sorry, Heart of Maui, I don't know any more information on these topics you mentioned. This book, however, seems to have more information on richettsia:

Notes on Medical Virology (Paperback)
by Morag C. Timbury (Author)

"This is a short well established textbook of medical virology. It also includes sections on chlamydia, richettsia and mycoplasma. The subject is largely presented in terms of presenting disease, discussing epidemiology, diagnosis, clinical features, complications and vaccines. the text is illustrated throughout with colour clinical photographs. The emphasis of the whole book is on information relevant to clinical practice."

Never heard of the 'r' thing myself, though this says:

"Members of genus Chlamydia lack peptidoglycan, are monomorphic cocci, consistently stain gram-negative, and utilize their host's ATP. Members of genus Richettsia have peptidoglycan, are pleomorphic cocci or rods, inconsistently stain gram-negative, are able to make their own ATP, and typically are acquired via arthropod vectors. "

To fight it, peptydoglycan seems to be dissolved with regular penicillin? Says here:

"Peptidoglycan, also known as murein, is a polymer consisting of sugars and amino acids that forms a mesh-like layer outside the plasma membrane of eubacteria. The sugar component consists of alternating residues of β-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid residues. Attached to the N-acetylmuramic acid is a peptide chain of three to five amino acids. The peptide chain can be cross-linked to the peptide chain of another strand forming the 3D mesh-like layer. Some Archaea have a similar layer of pseudopeptidoglycan. Peptidoglycan serves a structural role in the bacterial cell wall, giving structural strength, as well as counteracting the osmotic pressure of the cytoplasm. A common misconception is that peptidoglycan gives the cell its shape, however, while peptidoglycan helps maintain the structure of the cell, it is actually the MreB protein that facilitates cell shape. Peptidoglycan is also involved in binary fission during bacterial cell reproduction.[1]

The peptidoglycan layer is substantially thicker in Gram-positive bacteria (20 to 80 nm) than in Gram-negative bacteria (7 to 8 nm), with the attachment of the S-layer. Peptidoglycan forms around 90% of the dry weight of Gram-positive bacteria but only 10% of Gram-negative strains. In Gram-positive strains, it is important in attachment roles and sterotyping purposes.[2]

...

Antibiotic inhibition
Some antibacterial drugs such as penicillin interfere with the production of peptidoglycan by binding to bacterial enzymes known as penicillin-binding proteins
or transpeptidases[2]. Penicillin-binding proteins form the bonds between oligopeptide crosslinks in peptidoglycan. For a bacterial cell to reproduce through binary fission, more than a million peptidoglycan subunits (NAM-NAG+oligopeptide) must be attached to existing subunits.[3] Mutations in transpeptidases that lead to reduced interactions with an antibiotic are a significant source of emerging antibiotic resistance.[4]

Considered the human body's "own antibiotic", lysozymes found in tears work by breaking the β-(1,4)-glycosidic bonds in peptidoglycan (see below) and thereby destroying many bacterial cells. Antibiotics such as penicillin commonly target bacterial cell wall formation (of which peptidoglycan is an important component) because animal cells do not have cell walls."

Mark said...

Detox with DMSO?

DMSO Background Literature

DMSO: Many Uses, Much Controversy
by Maya Muir

Abstract

Dimethyl sulfoxide (DMSO), a by-product of the wood industry, has been in use as a commercial solvent since 1953.

It is also one of the most studied but least understood pharmaceutical agents of our time--at least in the United States. According to Stanley Jacob, MD, a former head of the organ transplant program at Oregon Health Sciences University in Portland, more than 40,000 articles on its chemistry have appeared in scientific journals, which, in conjunction with thousands of laboratory studies, provide strong evidence of a wide variety of properties. (See Major Properties Attributed to DMSO) Worldwide, some 11,000 articles have been written on its medical and clinical implications, and in 125 countries throughout the world, including Canada, Great Britain, Germany, and Japan, doctors prescribe it for a variety of ailments, including pain, inflammation, scleroderma, interstitial cystitis, and arthritis elevated intercranial pressure.

Yet in the United States, DMSO has Food and Drug Administration (FDA) approval only for use as a preservative of organs for transplant and for interstitial cystitis, a bladder disease. It has fallen out of the limelight and out of the mainstream of medical discourse, leading some to believe that it was discredited. The truth is more complicated.

DMSO: A History of Controversy

The history of DMSO as a pharmaceutical began in 1961, when Dr. Jacob was head of the organ transplant program at Oregon Health Sciences University. It all started when he first picked up a bottle of the colorless liquid. While investigating its potential as a preservative for organs, he quickly discovered that it penetrated the skin quickly and deeply without damaging it. He was intrigued. Thus began his lifelong investigation of the drug.

The news media soon got word of his discovery, and it was not long before reporters, the pharmaceutical industry, and patients with a variety of medical complaints jumped on the news.

Because it was available for industrial uses, patients could dose themselves. This early public interest interfered with the ability of Dr. Jacob--or, later, the FDA--to see that experimentation and use were safe and controlled and may have contributed to the souring of the mainstream medical community on it.

Why, if DMSO possesses half the capabilities claimed by Dr. Jacob and others, is it still on the sidelines of medicine in the United States today?

"It's a square peg being pushed into a round hole," says Dr. Jacob. "It doesn't follow the rifle approach of one agent against one disease entity. It's the aspirin of our era. If aspirin were to come along today, it would have the same problem. If someone gave you a little white pill and said take this and your headache will go away, your body temperature will go down, it will help prevent strokes and major heart problems--what would you think?"

Others cite DMSO's principal side effect: an odd odor, akin to that of garlic, that emanates from the mouth shortly after use, even if use is through the skin. Certainly, this odor has made double-blinded studies difficult. Such studies are based on the premise that no one, neither doctor nor patient, knows which patient receives the drug and which the placebo, but this drug announces its presence within minutes.

Others, such as Terry Bristol, a Ph.D. candidate from the University of London and president of the Institute for Science, Engineering and Public Policy in Portland, Oregon, who assisted Dr. Jacob with his research in the 1960s and 1970s, believe that the smell of DMSO may also have put off the drug companies, that feared it would be hard to market.

Worse, however, for the pharmaceutical companies was the fact that no company could acquire an exclusive patent for DMSO, a major consideration when the clinical testing required to win FDA approval for a drug routinely runs into millions of dollars.

In addition, says Mr. Bristol, DMSO, with its wide range of attributes, would compete with many drugs these companies already have on the market or in development.

The FDA and DMSO

In the first flush of enthusiasm over the drug, six pharmaceutical companies embarked on clinical studies. Then, in November 1965, a woman in Ireland died of an allergic reaction after taking DMSO and several other drugs. Although the precise cause of the woman's death was never determined, the press reported it to be DMSO. Two months later, the FDA closed down clinical trials in the United States, citing the woman's death and changes in the lenses of certain laboratory animals that had been given doses of the drug many times higher than would be given humans.

Some 20 years and hundreds of laboratory and human studies later, no other deaths have been reported, nor have changes in the eyes of humans been documented or claimed.

Since then, however, the FDA has refused seven applications to conduct clinical studies, and approved only 1, for intersititial cystitis, which subsequently was approved for prescriptive use in 1978.

Dr. Jacob believes the FDA "blackballed" DMSO, actively trying to kill interest in a drug that could end much suffering.

Jack de la Torre, MD, Ph.D., professor of neurosurgery and physiology at the University of New Mexico Medical School in Albuquerque, a pioneer in the use of DMSO and closed head injury, says, "Years ago the FDA had a sort of chip on its shoulder because it thought DMSO was some kind of snake oil medicine. There were people there who were openly biased against the compound even though they knew very little about it. With the new administration at that agency, it has changed a bit."

The FDA recently granted permission to conduct clinical trials in Dr. de la Torre's field of closed head injury.

DMSO Penetrates Membranes and Eases Pain

The first quality that struck Dr. Jacob about the drug was its ability to pass through membranes, an ability that has been verified by numerous subsequent researchers.1 DMSO's ability to do this varies proportionally with its strength--up to a 90 percent solution. From 70 percent to 90 percent has been found to be the most effective strength across the skin, and, oddly, performance drops with concentrations higher than 90 percent. Lower concentrations are sufficient to cross other membranes. Thus, 15 percent DMSO will easily penetrate the bladder.2

In addition, DMSO can carry other drugs with it across membranes. It is more successful ferrying some drugs, such as morphine sulfate, penicillin, steroids, and cortisone, than others, such as insulin. What it will carry depends on the molecular weight, shape, and electrochemistry of the molecules.

This property would enable DMSO to act as a new drug delivery system that would lower the risk of infection occurring whenever skin is penetrated.

DMSO perhaps has been used most widely as a topical analgesic, in a 70 percent DMSO, 30 percent water solution. Laboratory studies suggest that DMSO cuts pain by blocking peripheral nerve C fibers.3 Several clinical trials have demonstrated its effectiveness,4,5 although in one trial, no benefit was found.6 Burns, cuts, and sprains have been treated with DMSO. Relief is reported to be almost immediate, lasting up to 6 hours. A number of sports teams and Olympic athletes have used DMSO, although some have since moved on to other treatment modalities. When administration ceases, so do the effects of the drug.

Dr. Jacob said at a hearing of the U.S. Senate Subcommittee on Health in 1980, "DMSO is one of the few agents in which effectiveness can be demonstrated before the eyes of the observers....If we have patients appear before the Committee with edematous sprained ankles, the application of DMSO would be followed by objective diminution of swelling within an hour. No other therapeutic modality will do this."

Chronic pain patients often have to apply the substance for 6 weeks before a change occurs, but many report relief to a degree they had not been able to obtain from any other source.

DMSO and Inflammation

DMSO reduces inflammation by several mechanisms. It is an antioxidant, a scavenger of the free radicals that gather at the site of injury. This capability has been observed in experiments with laboratory animals7 and in 150 ulcerative colitis patients in a double-blinded randomized study in Baghdad, Iraq.8

DMSO also stabilizes membranes and slows or stops leakage from injured cells.

At the Cleveland Clinic Foundation in Cleveland, Ohio, in 1978, 213 patients with inflammatory genitourinary disorders were studied.

Researchers concluded that DMSO brought significant relief to the majority of patients. They recommended the drug for all inflammatory conditions not caused by infection or tumor in which symptoms were severe or patients failed to respond to conventional therapy.9

Stephen Edelson, MD, F.A.A.F.P., F.A.A.E.M., who practices medicine at the Environmental and Preventive Health Center of Atlanta, has used DMSO extensively for 4 years. "We use it intravenously as well as locally," he says. "We use it for all sorts of inflammatory conditions, from people with rheumatoid arthritis to people with chronic low back inflammatory-type symptoms, silicon immune toxicity syndromes, any kind of autoimmune process.

"DMSO is not a cure," he continues. "It is a symptomatic approach used while you try to figure out why the individual has the process going on. When patients come in with rheumatoid arthritis, we put them on IV DMSO, maybe three times a week, while we are evaluating the causes of the disease, and it is amazing how free they get. It really is a dramatic treatment."

As for side effects, Dr. Edelson says: "Occasionally, a patient will develop a headache from it, when used intravenously--and it is dose related." He continues: "If you give a large dose, [the patient] will get a headache. And we use large doses. I have used as much as 30ml IV over a couple of hours. The odor is a problem. Some men have to move out of the room [shared] with their wives and into separate bedrooms. That is basically the only problem."

DMSO was the first nonsteroidal anti-inflammatory discovered since aspirin.

Mr. Bristol believes that it was that discovery that spurred pharmaceutical companies on to the development on other varieties of nonsteroidal anti-inflammatories.

"Pharmaceutical companies were saying that if DMSO can do this, so can other compounds," says Mr. Bristol. "The shame is that DMSO is less toxic and has less int he way of side effects than any of them."

Collagen and Scleroderma

Scleroderma is a rare, disabling, and sometimes fatal disease, resulting form an abnormal buildup of collagen in the body.

The body swells, the skin--particularly on hands and face--becomes dense and leathery, and calcium deposits in joints cause difficulty of movement.

Fatigue and difficulty in breathing may ensue. Amputation of affected digits may be necessary. The cause of scleroderma is unknown, and, until DMSO arrived, there was no known effective treatment.

Arthur Scherbel, MD, of the department of rheumatic diseases and pathology at the Cleveland Clinic Foundation, conducted a study using DMSO with 42 scleroderma patients who had already exhausted all other possible therapies without relief.

Dr. Scherbel and his coworkers concluded 26 of the 42 showed good or excellent improvement.

Histotoxic changes were observed together with healing of ischemic ulcers on fingertips, relief from pain and stiffness, and an increase in strength. The investigators noted, "It should be emphasized that these have never been observed with any other mode of therapy."10 Researchers in other studies have since come to similar conclusions.11

Does DMSO Help Arthritis?

It was inevitable that DMSO, with its pain-relieving, collagen-softening, and anti-inflammatory characteristics, would be employed against arthritis, and its use has been linked to arthritis as much as to any condition. Yet the FDA has never given approval for this indication and has, in fact, turned down three Investigational New Drug (IND) applications to conduct extensive clinical trials.

Moreover, its use for arthritis remains controversial. Robert Bennett, MD, F.R.C.P., F.A.C.R., F.A.C.P., professor of medicine and chief, division of arthritis and rheumatic disease at Oregon Health Sciences University (Dr. Jacob's university), says other drugs work better. Dava Sobel and Arthur Klein conducted their own informal study of 47 arthritis patients using DMSO in preparation for writing their book, Arthritis: What Works, and came to the same conclusion.12

Yet laboratory studies have indicated that DMSO's capacity as a free-radical scavenger suggests an important role for it in arthritis.13 The Committee of Clinical Drug Trials of the Japanese Rheumatism Association conducted a trial with 318 patients at several clinics using 90 percent DMSO and concluded that DMSO relieved joint pain and increased range of joint motion and grip strength, although performing better in more recent cases of the disease.14 It is employed widely in the former Soviet Union for all the different types of arthritis, as it is in other countries around the world.

Dr. Jacob remains convinced that it can play a significant role in the treatment of arthritis. "You talk to veterinarians associated with any race track, and you'll find there's hardly an animal there that hasn't been treated with DMSO. No veterinarian is going to give his patient something that does not work. There's no placebo effect on a horse."

DMSO and Central Nervous System Trauma

Since 1971, Dr. de la Torre, then at the University of Chicago, has experimented using DMSO with injury to the central nervous system.

Working with laboratory animals, he discovered that DMSO lowered intracranial pressure faster and more effectively than any other drug.

DMSO also stabilized blood pressure, improved respiration, and increased urine output by five times and increased blood flow through the spinal cord to areas of injury.15-17 Since then, DMSO has been employed with human patients suffering severe head trauma, initially those whose intracranial pressure remained high despite the administration of mannitol, steroids, and barbiturates.

In humans, as well as animals, it has proven the first drug to significantly lower intracranial pressure, the number one problem with severe head trauma.

"We believe that DMSO may be a very good product for stroke," says Dr. de la Torre, "and that is a devastating illness which affects many more people than head injury. We have done some preliminary clinical trials, and there's a lot of animal data showing that it is a very good agent in dissolving clots."

Other Possible Applications for DMSO

Many other uses for DMSO have been hypothesized from its known qualities hand have been tested in the laboratory or in small clinical trials. Mr. Bristol speaks with frustration about important findings that have never been followed up on because of the difficulty in finding funding and because "to have on your resume these days that you've worked on DMSO is the kiss of death." It is simply too controversial. A sampling of some other possible applications for this drug follows.

DMSO has long been used to promote healing.

People who have it on hand often use it for minor cuts and burns and report that recovery is speedy.

Several studies have documented DMSO use with soft tissue damage, local tissue death, skin ulcers, and burns.18-21

In relation to cancer, several properties of DMSO have gained attention. In one study with rats, DMSO was found to delay the spread of one cancer and prolong survival rates with another.22 In other studies, it has been found to protect noncancer cells while potentiating the chemotherapeutic agent.

Much has been written recently about the worldwide crisis in antibiotic resistance among bacteria (see Alternative & Complementary Therapies, Volume 2, Number 3, 1996, pages 140-144) Here, too, DMSO may be able to play a role. Researcher as early as 1975 discovered that it could break down the resistance certain bacteria have developed.23

In addition to its ability to lower intracranial pressure following closed head injury, Dr. de la Torre's work suggests that the drug may actually have the ability to prevent paralysis, given its ability to speedily clean out cellular debris and stop the inflammation that prevents blood from reaching muscle, leading to the death of muscle tissue.

With its great antioxidant powers, DMSO could be used to mitigate some of the effects of aging, but little work has been done to investigate this possibility. Toxic shock, radiation sickness, and septicemia have all been postulated as responsive to DMSO, as have other conditions too numerous to mention here.

DMSO in the Future

Will DMSO ever sit on the shelves of pharmacies in this country as a legal prescriptive for many of the conditions it may be able to address?

Will the studies we need to discover when this drug is most appropriate ever be done?

Given the difficulties the drug has run into so far and the recent development of new drugs that perform some of the same functions, Mr. Bristol is doubtful. Others, however, such as Dr. Jacob and Dr. de la Torre, see the FDA approval of DMSO for interstitial cystitis and the more recent FDA go-ahead for DMSO trials with closed head injury as new indications of hope.

The cystitis approval means that physicians may use it at their discretion for other uses, giving DMSO a new legitimacy.

Dr. Jacob continues to believe that DMSO should not even be called a drug but is more correctly a new therapeutic principle, with an effect on medicine that will be profound in many areas.

Whether that is true cannot be known without extensive a publicly reported trials, which are dependent on the willingness of researchers to undertake rigorous studies in this still-unfashionable tack and of pharmaceutical companies and other investors to back them up.

That this is a live issue is proved by the difficulty the investigators with approval to test DMSO for closed head injury clinically are having finding funds to conduct the trials.

In 1980, testifying before the Select Committee on Agin of the U.S. House of Representatives, Dr. Scherbel said, "The controversy that exists over the clinical effectiveness of DMSO is not well-founded--clinical effectiveness may be variable in different patients. If toxicity is consistently minimal, the drug should not be restricted from practice. The clinical effectiveness of DMSO can be decided with complete satisfaction if the drug is made available to the practicing physician. The number of patient complaints about pain and the number of phone calls to the doctor's office will decide quickly whether or not the drug is effective."

It may be premature to call for the full rehabilitation of DMSO, but it is time to call for a full investigation of its true range of capabilities.

References

1. Kolb, K.H., Jaenicke, G., Kramer, M., Schulze, P.E. Absorption, distribution, and elimination of labeled dimethyl sulfoxide in man and animals. Ann NY Acad Sci 141:85-95, 1967.
2. Herschler, R., Jacob, S.W. The case of dimethyl sulfoxide. In: Lasagna, L. (Ed.), Controversies in Therapeutics. Philadelphia: W.B. Saunders, 1980.
3. Evans, M.S., Reid, K.H., Sharp, J.B. Dimethyl sulfoxide (DMSO) blocks conduction in peripheral nerve C fibers: A possible mechanism of analgesia. Neurosci Lett 150:145-148, 1993.
4. Demos, C.H., Beckloff, G.L., Donin, M.N., Oliver, P.M. Dimethyl sulfoxide in musculoskeletal disorders. Ann NY Acad Sci 141:517-523, 1967.
5. Lockie, L.M., Norcross, B. A clinical study on the effects of dimethyl sulfoxide in 103 patients with acute and chronic musculoskeletal injures and inflammation. Ann NY Acad Sci 141:599-602, 1967.
6. Percy, E.C., Carson, J.D. The use of DMSO in tennis elbow and rotator cuff tendinitis: A double-blind study. Med Sci Sports Exercise 13:215-219, 1981.
7. Itoh, M., Guth, P. Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat. Gastroenterology 88:1126-1167, 1985.
8. Salim, A.S., Role of oxygen-derived free radical scavengers in the management of recurrent attacks of ulcerative colitis: A new approach. J. Lab Clin Med 119:740-747, 1992.
9. Shirley, S.W., Stewart, B.H., Mirelman, S. Dimethyl sulfoxide in treatment of inflammatory genitourinary disorders. Urology 11:215-220, 1978.
10. Scherbel, A.L., McCormack, L.J., Layle, J.K. Further observations on the effect of dimethyl sulfoxide in patients with generalized scleroderma (progressive systemic sclerosis). Ann NY Acad Sci 141:613-629, 1967.
11. Engel, M.F., Dimethyl sulfoxide in the treatment of scleroderma. South Med J 65:71, 1972.
12. Sobel, D., Klein, A.C. Arthritis: What Works. New York: St. Martins Press, 1989.
13. Santos, L., Tipping, P.G. Attenuation of adjuvant arthritis in rats by treatment with oxygen radical scavengers. Immunol Cell Biol 72:406-414, 1994.
14. Matsumoto, J. Clinical trials of dimethyl sulfoxide in rheumatoid arthritis patients in Japan. Ann NY Acad Sci 141:560-568, 1967.
15. de la Torre, J.C., et al. Modifications of experimental spinal cord injuries using dimethyl sulfoxide. Trans Am Neurol Assoc 97:230, 1971.
16. de la Torre, J.C., et al. Dimethyl sulfoxide in the treatment of experimental brain compression. J Neurosurg 38:343, 1972.
17. de la Torre, J.C., et al. Dimethyl sulfoxide in the central nervous system trauma. Ann NY Acad Sci 243:362, 1975.
18. Lawrence, H.H., Goodnight, S.H. Dimethyl sulfoxide and extravasion of anthracycline agents. Ann Inter Med 98:1025, 1983.
19. Lubredo, L., Barrie, M.S., Woltering, E.A. DMSO protects against adriamycin-induced skin necrosis. J. Surg Res 53:62-65, 1992.
20. Alberts, D.S., Dorr, R.T. Case report: Topical DMSO for mitomycin-C-induced skin ulceration. Oncol Nurs Forum 18:693-695, 1991.
21. Cruse, C.W., Daniels, S. Minor burns: Treatment using a new drug deliver system with silver sulfadiazine. South Med J 82:1135-1137, 1989.
22. Miller, L., Hansbrough, J., Slater, H., et al. Sildimac: A new deliver system for silver sulfadiazine in the treatment of full-thickness burn injuries. J Burn Care Rehab 11:35-41, 1990
23. Salim, A. Removing oxygen-derived free radicals delays hepatic metastases and prolongs survival in colonic cancer. Oncology 49:58-62, 1992.
24. Feldman, W.E., Punch, J.D., Holden, P. In vivo and in vitro effects of dimethyl sulfoxide on streptomycin-sensitive and resistant Escherichia coli. Ann Acad Sci 141:231, 1967.

Source: Alternative & Complementary Therapies, July/August 1996, pages 230-235. DMSO Organization would like to thank the publisher for permission to place this fine article on the World Wide Web. The Publisher retains all copyright. To order reprints of this article, write to or call: Karen Ballen, Alternative & Complementary Therapies, Mary Ann Liebert, Inc., 2 Madison Avenue, Larchmont, NY 10538, (914) 834-3100.

---
http://www.dmso.org/articles/information/muir.htm

Mark said...

Black Cohosh Stops Breast Cancer Growth

[A repost from Dr. Mercola]

A new laboratory study, published in /Phytomedicine/, suggests that extracts from black cohosh, an herb most commonly used to reduce menopausal symptoms such as hot flashes, may stop breast cancer cells in their tracks. This adds more evidence to a small but growing body of research suggesting that black cohosh could have a use in breast cancer prevention.

Black cohosh (Cimicifugae racemosae rhizome), is a perennial plant native to North America, is a member of the buttercup family.

It has long been a popular alternative to hormone replacement therapy (HRT) in many countries.

In the UK, 9 million days’ worth of black cohosh supplements were purchased in 2004.

The inhibition of the growth of breast cancer cells was related to an induction of programmed cell death (apoptosis).

"These results corroborate the results of our previous studies indicating that the growth inhibitory effect of actein or an extract of black cohosh is associated with activation of specific stress response pathways and apoptosis," wrote the researchers, referring to their studies published earlier this year in Anticancer Research and the International Journal of Cancer.

Although the results are promising, further research is needed to determine whether the herb can be effectively used as a breast cancer chemopreventive agent.

Sources:

* FoodAndDrinkEurope.com November 13, 2007
(http://www.foodanddrinkeurope.com/news/ng.asp?n=81302&m=1FDEN13&c=eepddtxhprfgmgi)

* Phytomedicine October 31, 2007 [Epub Ahead of Print]
(http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed&db=PubMed&cmd=Search&TransSchema=title&term=%22Phytomedicine%20%3A%20international%20journal%20of%20phytotherapy%20and%20phytopharmacology%22%5BJour%5D%20AND%202007%5Bpdat%5D%20AND%20Cimicifuga)

* Anticancer Research March-April, 2007;27(2):697-712
(http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed&db=PubMed&cmd=Search&term=Anticancer%20research%5BJour%5D%20AND%20697%5Bpage%5D%20AND%202007%5Bpdat%5D)

* International Journal of Cancer November 1, 2007;121(9):2073-83
(http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed&db=PubMed&cmd=Search&term=%22International%20journal%20of%20cancer.%20Journal%20international%20du%20cancer%22%5BJour%5D%20AND%202073%5Bpage%5D%20AND%202007%5Bpdat%5D)

Dr. Mercola's Comments:

First of all, for those of you who are new to the newsletter; let me make it perfectly clear that while I view herbs as frequently helpful and virtually non-toxic when compared to patent drugs, they rarely treat the cause of the disease. I view most of them as symptomatic band-aids. They should rarely be used without addressing the underlying cause of the disease, which is precisely what I address in the hundreds of thousands of pages on my site.

Having said that, black cohosh was first listed in the United States Pharmacopoeia (the nation's official drug reference book), from 1820 to 1926. But at that point, drug manufacturers began focusing almost exclusively on synthetic molecules that, unlike herbs, could be patented and used to make big profits. So research stopped, and medicinal plants like black cohosh were dropped from use in conventional medicine.


However, in more recent years, studies have shown that black cohosh is nearly as effective as estrogen (http://www.mercola.com/2001/may/19/estrogen.htm) -- and far more effective than placebo pills -- at treating hot flashes, and is also useful in managing the mood swings and irritability that can accompany menopause.

And now we’re beginning to see its value in dealing with cancer.

The catch-22 is that black cohosh has also been found to interfere with drugs and radiation treatments used in conventional cancer therapy (http://www.mercola.com/2005/may/14/black_cohosh.htm) by:

* Increasing cell killing by two of the drugs (Adriamycin and Taxotere)
* Decreasing the effectiveness of one drug (Platinol)
* Not altering the effects of radiation or a fourth drug (4-hydroperoxycyclophosphamide)

Therefore, if you’re being treated for breast cancer through conventional cancer treatments you should definitely consult with your physician before using black cohosh on your own.

Cancer treatment is one that I typically don't focus on for a variety of reasons. [Because that's where the big corrupt money is and Mercola wants to stay out of it's vicious shadow and turf! "Remember the apricot" in the story and films posted above. ]

[Essiac is another.]

But needless to say, there are a large variety of naturally-based treatments that you could use for cancer, in which black cohosh would not be a problem.

There are also a number of other options available that can help you prevent breast cancer.

My Cancer-Busting Dozen Approaches

I believe you can VIRTUALLY ELIMINATE your cancer risk and radically improve your risk of recovering from cancer if you currently have it. All you need to do is follow these relatively simple risk reduction strategies.

You won’t read or hear much about them because they have not been formally "proven" yet by conservative researchers.

However, most people do not know that 85 percent of therapies currently recommended by conventional medicine have never been formally proven either.

So here are the Twelve Strategies

1. Reduce your processed food, sugar and grain carbohydrate intake
(http://www.mercola.com/2005/apr/27/breast_cancer.htm) Yes, this is even true for whole unprocessed organic grains as they tend to rapidly break down and drive your insulin and leptin levels up, which is the last thing you need to have happening if you are seeking to resolve a cancer.

2. Control your fasting insulin and leptin levels (http://www.mercola.com/2001/jul/14/insulin.htm): This is the end result, and can be easily monitored with the use of simple and relatively inexpensive blood tests.

3. Normalize your ratio of omega-3 to omega-6 fats
(http://www.mercola.com/2002/mar/23/omega3.htm) by taking a
high-quality krill oil or fish oil and reducing your intake of
most processed vegetable oils

4. Get regular exercise
(http://www.mercola.com/2004/mar/20/exercise_cancer.htm). One of
the primary reasons exercise works is that it drives your insulin
levels down. Controlling insulin levels is one of the most
powerful ways to reduce your cancer risks.

5. Normalize your vitamin D levels
(http://www.mercola.com/2004/apr/10/vitamin_d_cancer.htm) and
vitamin A levels
(http://www.mercola.com/2005/jan/19/vitamin_a.htm) by getting
plenty of sunlight exposure
(http://www.mercola.com/2004/mar/31/cancer_sunlight.htm) and
consider careful supplementation when this is not possible. If you
take oral vitamin D and have a cancer it would be very prudent to
monitor your vitamin D blood levels regularly.

6. Get a good night's sleep
(http://www.mercola.com/1998/archive/breast_cancer_risk.htm)

7. Eat according to your nutritional type
(http://www.mercola.com/2003/feb/26/metabolic_typing.htm). The
potent anti-cancer effects of this principle are very much
underappreciated. When we treat cancer patients in our clinic this
is one of the most powerful anti-cancer strategies we have

8. Reduce your exposure to environmental toxins
(http://www.mercola.com/2000/jul/16/cancer_environment.htm) like
pesticides, household chemical cleaners, synthetic air fresheners
(http://www.mercola.com/2004/may/26/electric_air_fresheners.htm)
and air pollution

9. Limit your exposure and provide protection for yourself from
information carrying radio waves produced by cell phone towers,
base stations, phones and WiFi stations

10. Avoid frying or charbroiling your food.
(http://www.mercola.com/2003/aug/2/acrylamide_cancer.htm)Boil,
poach or steam your foods instead

11. Have a tool to permanently reprogram the neurological
short-circuiting that can activate cancer genes
(http://www.emofree.com/articles/cancer-group-results.htm). Even
the CDC states that 85 percent of disease is caused by emotions
(http://articles.mercola.com/sites/articles/archive/2007/08/21/a-new-view-of-cancer-german-new-medicine.aspx).
It is likely that this factor may be more important than all the
other physical ones listed here, so make sure this is addressed.
Energy psychology seems to be one of the best approaches and my
particular favorite tool, as you may know, is the Emotional
Freedom Technique (http://www.mercola.com/forms/eftcourse.htm).
German New Medicine
(http://articles.mercola.com/sites/articles/archive/2007/08/21/a-new-view-of-cancer-german-new-medicine.aspx)
is another powerful tool

12. Use broccoli sprouts
(http://www.mercola.com/2004/sep/22/broccoli_cancer.htm) as an
adjunct to everything above unless you simply do not like broccoli


Related Articles:

How Black Cohosh Can Tame a Woman's Hot Flashes (http://www.mercola.com/2007/jan/11/how-black-cohosh-can-tame-a-womans-hot-flashes.htm)
The Estrogen Alternative -- Black Cohosh (http://www.mercola.com/2001/may/19/estrogen.htm)
The Downside of Taking Black Cohosh (http://www.mercola.com/2005/may/14/black_cohosh.htm)

Mark said...

Flax Oil As a True Aid Against Arthritis Heart Infarction Cancer and Other Diseases (3rd Edition):

"[Her other book:] The Oil-Protein Diet Cookbook,

a review of July 10, 2001
By r.k. ullery (Gobles, Michigan United States)

After reaching late middle-age, I began to see a deterioration in the general health of myself and my friends. Knowing our forebearers reached old age in reasonably good health, I started reading everything from medical reports to junk mail in an attempt to understand what is different in this day from the past. One of the most revealing, and believable, reports I read is a book that is not really a book. It is "Flax Oil as a True Aid Against Arthritis, Heart Infarction, Cancer and Other Diseases" by Dr. Johanna Budwig. The book was not written as a book, but is the actual report she gave as a Nobel Prize winning researcher to her fellows in the medical field. The facts she presented made complete sense, but did not list how the reader could utilize the information. Hence, I ordered her book, "The Oil-Protein Diet Cookbook". In it, she explains how the reader can put her theories of introducing flax oil to the diet in very interesting ways. She has included over 500 simple recipes with which one can incorporate the beneficial flax oil into one's lifestyle. The most helpful part is the recipes for a basic cream to replace the vegetable fat usually spread on our breads and melted over our veggies, and a very simple granola-type cereal one can use in many ways. With these two items, the diet we are used to can easily be replaced with one that may be able to "fix" what is broken in our bodies. She claims the faithful can completely cure such things as cancer, heart problems, and even diabetes. In talking to folks older even than me, some fondly remember having their mothers make them ingest flax seeds in one form or another. Dr. Budwig claims flax seed products cannot possibly hurt, even if taken in large amounts. I am listening to her and have begun to change my ways to hers. She must know something, as she is well into her 90's and still active!"

Mark said...

'New' Way to Kill Viruses: Shake Them to Death

[It's hardly new. Raymond Rife (see the books at my link of books about medical technology/treatment choices) should be more well known. Rife discovered this so called 'new effect' over 80 years ago. It has been the subject of medical-money blackout ever since because it provides a very cheap and unpatentable manner of medicine. Rife's legacy gets big money out of medicine (which has zero incentive to heal people instead of make them medical treatment junkies over and over in perpetual states of ill health), and gets big healing into medicine instead.]


By Michael Schirber, Special to LiveScience

Scientists may one day [sic] be able to destroy viruses in the same way that opera singers presumably shatter wine glasses. New [sic] research mathematically determined the frequencies at which simple viruses could be shaken to death.

"The capsid of a virus is something like the shell of a turtle," said physicist Otto Sankey of Arizona State University. "If the shell can be compromised [by mechanical vibrations], the virus can be inactivated."

Recent experimental evidence has shown that laser pulses tuned to the right frequency can kill certain viruses. However, locating these so-called resonant frequencies is a bit of trial and error.

"Experiments must just try a wide variety of conditions and hope that conditions are found that can lead to success," Sankey told LiveScience.

To expedite this search, Sankey and his student Eric Dykeman have developed a way to calculate the vibrational motion of every atom in a virus shell. From this, they can determine the lowest resonant frequencies.

As an example of their technique, the team modeled the satellite tobacco necrosis virus and found this small virus resonates strongly around 60 Gigahertz (where one Gigahertz is a billion cycles per second), as reported in the Jan. 14 issue of Physical Review Letters.

A virus' death knell

All objects have resonant frequencies at which they naturally oscillate. Pluck a guitar string and it will vibrate at a resonant frequency.

But resonating can get out of control. A famous example is the Tacoma Narrows Bridge, which warped and finally collapsed in 1940 due to a wind that rocked the bridge back and forth at one of its resonant frequencies.

Viruses are susceptible to the same kind of mechanical excitation. An experimental group led by K. T. Tsen from Arizona State University have recently shown that pulses of laser light can induce destructive vibrations in virus shells.

"The idea is that the time that the pulse is on is about a quarter of a period of a vibration," Sankey said. "Like pushing a child on a swing from rest, one impulsive push gets the virus shaking."

It is difficult to calculate what sort of push will kill a virus, since there can be millions of atoms in its shell structure. A direct computation of each atom's movements would take several hundred thousand Gigabytes of computer memory, Sankey explained.

He and Dykeman have found a method to calculate the resonant frequencies with much less memory.

In practice

The team plans to use their technique to study other, more complicated viruses. However, it is still a long way from using this to neutralize the viruses in infected people. [er, why is that?]

One challenge is that laser light cannot penetrate the skin very deeply. [false--you don't have to have a dependence on laser light techniques to deliver the waves--read some Rife.]

But Sankey imagines that a patient might be hooked up to a dialysis-like machine that cycles blood through a tube where it can be hit with a laser. Or perhaps, ultrasound can be used instead of lasers. [ultrasound has its own health problems. Just read some Rife, people.]

These treatments would presumably be safer [and much cheaper] for patients than many antiviral drugs that can have terrible side-effects. Normal cells should not be affected by the virus-killing lasers or sound waves because they have resonant frequencies much lower than those of viruses, Sankey said.

Moreover, it is unlikely that viruses will develop resistance to mechanical shaking, as they do to drugs.

"This is such a new field [sic, false; it's an old field with long term repression of the information], and there are so few experiments, that the science has not yet had sufficient time to prove itself," Sankey said. "We remain hopeful but remain skeptical at the same time."

---
http://www.livescience.com/health/080205-virus-shattering.html

Mark said...

NaturalNews.com printable article
Originally published August 1 2006

Natural Cellular Defense removes heavy metals, pesticides, toxic chemicals from body - study
by Mike Adams

---------------------


[there are links throughout the original article, so go there]

"In my research to develop a detoxification system for prospective mothers, I recently learned about a naturally occurring mineral called zeolite, which has a unique, negatively charged, crystalline structure. Zeolite is formed from the fusion of lava and ocean water, and combines all four elements. I feel that zeolite is an alchemical gift from God. It has been used for more than 800 years in Asia as a remedy for overall health and well-being, and is on the FDA’s GRAS list (generally recognized as safe). Zeolite is available commercially in a purified, activated form, in the zeolite product.

The results of research on zeolite are very impressive:..."


---------------------

full article (without links):

Natural Cellular Defense is a natural zeolite-based substance that is being increasingly studied for its near-miraculous ability to bind with heavy metals and toxic chemicals, removing them from the body. Dr. Gabriel Cousens, M.D., is leading the research on the use of Natural Cellular Defense to remove these chemicals from the body, and this article shares his latest results.

Those results are quite remarkable, as you will see below. Given that virtually every person living in modern society today has hundreds of synthetic chemicals in their bodies that do not belong there, and with the documented proof that combining Natural Cellular Defense with a simple juice fast can remove 88 percent of those chemicals from the body, this is research of tremendous importance. Its importance cannot be overstated when discussing the prevention of cancer, Alzheimer's, birth defects and even diabetes.

For anyone interested in acquiring Natural Cellular Defense products, contact information is listed at the end of this report. Neither Truth Publishing nor its writers has any financial interest whatsoever in this product.

From Dr. Gabriel Cousens

As a natural holistic physician, I, Gabriel Cousens, M.D., M.D.(H) Diplomate of the American Board of Holistic Medicine, Diplomate of Ayurveda have come across a major breakthrough in detoxifying the human body of the carcinogens, heavy metals, viruses, bacteria, fungi, and overall acid conditions that promote and cause disease.

Some 70,000 chemicals are being dumped into our environment, 65,000 of which are potentially hazardous to our health. We live in a virtual sea of pollutants, and carry many of these toxins within us. They can be found even in unborn children. A 2004 study by the Environmental Working Group identified 287 industrial chemicals in babies� umbilical-cord blood, including 180 known to cause cancer and 217 that are toxic to the brain and nervous system.

In my research to develop a detoxification system for prospective mothers, I recently learned about a naturally occurring mineral called zeolite, which has a unique, negatively charged, crystalline structure. Zeolite is formed from the fusion of lava and ocean water, and combines all four elements. I feel that zeolite is an alchemical gift from God. It has been used for more than 800 years in Asia as a remedy for overall health and well-being, and is on the FDA�s GRAS list (generally recognized as safe). Zeolite is available commercially in a purified, activated form, in the zeolite product.

The results of research on zeolite are very impressive:

1. Zeolite appears to prevent and may become an important treatment for cancer. In one study, 78 percent of the 65 participants with terminal cancer (many types) are now in complete remission for 12 months (LifeLink Pharmaceuticals, 2005, currently not published).
2. It has a chelation-like effect in removing heavy metals (particularly lead, mercury, cadmium, and arsenic), pesticides, herbicides, PCBs, and other toxins from the body, shown in a study of miners at Duke University. These toxins are strongly correlated with the occurrence of a wide range of diseases, including cancers and neurological disorders such as Alzheimer�s, autism, and dementia.
3. Zeolite also improves liver function, indirectly improving elimination of pesticides, herbicides, and xeno-estrogens.
4. Zeolite appears to block viral replication, and may prove to be a potent anti-viral and general remedy for all viruses. To date, 40 anecdotal cases of herpes zoster have reportedly been healed. Preliminary anecdotal case studies suggest that it may help alleviate rheumatoid arthritis, multiple sclerosis, and hepatitis C as well as the common cold and flu.
5. Zeolite�s binding power was proven during the Chernobyl disaster, when tons of it were used to remove radioactive cesium and strontium-90 before they contaminated local water systems.
6. Zeolite creates a natural buffer in the system by establishing an optimal pH level (between 7.35 and 7.45), which in turn activates healthy brain function and a strong immune system.
7. It is an effective detoxifier for prospective mothers and fathers. Anecdotal evidence and centuries of use in Asia suggest that zeolite is safe to use even during pregnancy and breastfeeding, although its safe use in pregnancy has not been proven in double-blind studies.

A pilot study at the Tree of Life Rejuvenation Center with 55 people, based on my non-toxic baby protocol for preparing parents to bring forth non-toxic babies, consisted of a one-week green juice fast and detox support program with zeolite in the form of Natural Cellular Defense (NCD) 15 drops, 4X/day. The following very significant results were found. 18 people were tested for depleted uranium (DU), a very serious worldwide radioactive contamination resulting from the use of DU armaments, especially used in Iraq.

Sixteen of the 18 people tested initially had DU in at least the liver, the breast, or the brain, and 13 of the 18 people had started with it in all three organs, the liver, the breast, and the brain. In one week on this protocol, all the people became DU-free except for one person, who still had DU in the liver. Also, thirty-two people were tested for Teflon and Perfluorooctanoic acid (PFOA), the carcinogenic element of teflon. Teflon was found in the livers of 27 people, the breasts of 25 people, and the brains of 28 people. All but two people became teflon-free after one week. Only one person had Teflon remaining in the breast, and one person had Teflon remaining in the brain.

In the same 32 people, initially PFOA was found in the liver of 28 people, the breast of 29 people, and the brain of 28 people. After one week, all people became PFOA-free except for one person having PFOA remaining in the breast and brain. In testing people for a whole set of toxins consisting of 14 to 26 of the common heavy metals, pesticides, and herbicides, the people initially had on average 90 to 95% of the toxins in their liver, breast, and brain, whether they were live-food eaters or not.

The overall percentage of removal of these toxins from these organs was 88%, leaving only 12% of the toxins in their systems overall. This included 91% removal from the liver, 88% removal from the breast, and 87% removal from the brain. In the 55 people tested the heavy metals, pesticides, and herbicide toxins, initially 801 toxins were found in the subjects� livers, 825 toxins in the breasts, 824 toxins in the brain. After the one-week protocol, just 73 toxins were left in the liver, 102 toxins left in the breast, and 111 toxins left in the brain:

Results of Week-Long NCD and Juice Fasting Non-Toxic Baby Protocol
LIVER BREAST BRAIN TOTAL
Toxins Found BEFORE 801 825 824 2450
Toxins Found AFTER 73 103 111 287
Percentage Removed 91% 88% 87% 88%

The four subjects who continued the green juice fasting with NCD for two weeks went down to 0 toxins, a 100% removal rate. These results suggest a powerful synergy of NCD plus a detoxifying green juice fast. In observing thousands of fasters since 1988, fasting alone�although wonderful for enhancing the vital force�does not seem to significantly get rid of pesticides, herbicides, and heavy metals after 1 week by itself. I am proposing a theoretical model for explaining the testimonials of the powerful, across-the-board healing effects of NCD (a purified zeolite) from such health problems as ADD/Hyperactivity, Addiction, Agent Orange Exposure, Arthritis, Autism, Cancer, Cysts and Tumors, Depression, DES Exposure, Diabetes, Fibromyalgia, Flu, Colds, and Respiratory Problems, Gastro-Intestinal Problems, Heavy Metal Poisoning, Hepatitis C, High Blood Pressure, HIV/AIDS, Kidney Stones, Lack of Mental Clarity, Pain, PMS/Menstrual Pain, Silicone Breast Implant Toxicity, Skin Conditions, Spider Bite, Toothache/Gum Disease, Varicose and Spider Veins, Viral and Other Infections, Yeast Infections.

The model is a foundational healing concept. The basic mechanism we can draw from the literature and my present pilot study is that, by removing heavy metals, pesticides, herbicides, and DU, as well as through its effect of increasing immune system function, alkalizing the blood, blocking viral replication, and neutralizing free radicals, the NCD removes the blocks which compromise the vital life force. When the vital life force is freed up and activated, the body�s natural ability does the healing and relieving of these chronic diseases itself. With the NCD, we have returned to the basic natural healing theory for all chronic diseases. NCD is truly an alchemical gift from the Divine.

Also:

* According to testimonials, zeolite promotes a sense of well-being, clarity, and happiness. It appears to do this as a consequence of eliminating toxins and also, according to preliminary research, by increasing serotonin production. One study suggests that zeolite also helps relieve depression.
* Anecdotal reports suggest that zeolite increases energy, immune function, and general health.
* Zeolite neutralizes the formation of nitrosamines in the stomach. Found in processed meats, nitrosamines are one cause of stomach cancer. Another positive effect on the stomach, according to many anecdotal reports, is relief of acid reflux.

* Testimonials suggest that zeolite captures triggering antigens, which cause allergies, migraines, and asthma, decreasing the rate and severity of these symptoms.

* Zeolite directly absorbs free radicals and thus decreases free radical activity and damage to the body.

This zeolite product is a clear liquid that, taken daily as oral drops, supports us in living healthy, happy, and active lives in an increasingly toxic world. For more information on this article, please call the Tree of Life at 866-394-2520 toll-free, or go to the Tree of Life Rejuvenation Center's website, www.treeoflife.nu, or call Jason D. Groode at Pacific Rim Marketing (800) 309-9126.

Gabriel Cousens, M.D., M.D.(H), Diplomate American Board of Holistic Medicine, Diplomate Ayurveda, Director and Workshops Facilitator of the Tree of Life Rejuvenation Center, Host of Physician of the Soul and Creating Peace by Being Peace, Internet Radio Programs, and Author of Spiritual Nutrition, Conscious Eating, Depression-Free for Life, Rainbow Green Live-Food Cuisine, and Sevenfold Peace.

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http://www.naturalnews.com/019825.html

Mark said...

"Green juice" is mentioned above with the zeolite. For expecting mothers, this is obviously for the mothers, instead of the infants.

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Aojiru (青汁, Aojiru) is a Japanese vegetable drink most commonly made from kale. The drink is also known as green drink or green juice in English, a direct translation of the Japanese meaning. (In modern Japanese, the character 青 ao means "blue", but it is commonly still used in older contexts to refer to green vegetation.)

Aojiru was developed in October 1943 by Dr. Niro Endo (遠藤仁郎, Endō Nirō?), an army doctor who experimented with juices extracted from the discarded leaves of various vegetables in an attempt to supplement his family's meager wartime diet. He credited the cure of his son from pneumonia and of his wife from nephritis to aojiru, and in 1949 concluded that kale was the best ingredient for his juice.[1]

Aojiru was popularized in 1983 by {{nihongoQ'SAIキューサイ}}, who started marketing 100% kale aojiru in powdered form as a dietary supplement, and sales boomed after 2000 when cosmetics giant Fancl started mass retailing of the juice.[1]

Today, many Japanese companies manufacture aojiru, usually using kale, young barley or komatsuna leaves as the base of the drink, and the size of the aojiru market was well over $500 million in 2005.[2]

The taste of aojiru is famously unpleasant, so much so that drinking a glass of the liquid is a common punishment on Japanese TV game shows.[citation needed] However, new formulations of aojiru have attempted to minimize the bitter taste of the original.

[edit] References

1. ^ a b Japanese Aojiru - Tree Kale Juice. Kateigaho (Spring 2005). Retrieved on 2007-02-05.
2. ^ Paul Yamaguchi (2006-01-01). Japan’s Nutraceuticals Today - End of Year Japanese Nutraceutical Industry Thoughts and Looking Beyond. NPIcenter. Retrieved on 2007-02-05.

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http://en.wikipedia.org/wiki/Green_juice

2.

Japan’s Nutraceuticals Today - End of Year Japanese Nutraceutical Industry Thoughts and Looking Beyond
2006-01-01 - NPIcenter - Paul Yamaguchi

薬食同源 Japan’s Nutraceuticals Today

By Paul Yamaguchi

The State of Nutraceuticals in Japan

Good News and Bad News
In the survey of winter bonuses by Nikkei, the Japanese newspaper showed that bonuses rose by 3.54 percent to an average 804,458 yen or $6,688. The Financial Times reported bonuses at manufacturers rose 4.31 percent. The same paper said that workers at Toyota, which has been making record profits and is on target to overtake General Motors as the world's biggest carmaker, were asking for a basic pay rise for the first time in four years.

The New York Times reported that most economists and analysts believe the economic recovery seems to be real, with its roots extending throughout the Japanese economy.

The Japanese economy is projected to be growing at a faster rate for this year than that of Europe. Japan, Asia's biggest economy and the world's second largest, is finally rebounding after years of spiraling price declines. The government has set its long-term goal of ending deflation and achieving nominal GDP growth of around 2 percent next fiscal year according to an Associated Press news story.

Based on these reports, it appears that the Japanese economy is finally recovering and setting the stage for solid growth in 2006. Winter bonuses are most likely going to be put into savings accounts, but sales for big-ticket items such as high-end consumer electronics are up; spending for leisure and travel is also up. As the Japanese economy improves, consumer confidence is also increasing and people are spending more money.

Among income and spending increases, the Japanese nutraceutical industry also grew in 2005; it may top the $30 billion mark by the end of this year. The bad news is that the rate of annual growth is only about 6 percent, much slower than the 12 percent of last year and 15 percent from 2 years ago. The growth of the dietary supplement sector is expected to be about 4 percent this year, the smallest growth in 7 years. Has the booming health industry already reached its peak? Or is this just a temporary slow-down? It is still too early to judge but we should keep a close eye on future sales trends. As 2005 comes to a close, let’s take a look at the state of the Japanese nutraceutical industry:

The Ill-Fated FOSHU Overhaul

The regulatory environment surrounding the industry is more confusing than a year ago. The government‘s inability to adopt a new dietary supplement law resulted in impractical new FOSHU regulations. Earlier this year, the MHLW announced a new FOSHU regulation for three new FOSHU categories: qualified, standardized, and disease risk-reduction claim FOSHUs. They were designed to ease the approval process and expand FOSHU’s regulatory umbrella. After 12 months of implementation, there have been no new health claims granted under the new FOSHU categories because of the stringent requirements surrounding clinical and human test results: “the government created new doors for easier entry, but when opened, there is a new wall standing in front of you” said The Health Industry News. Last August, several economic organizations proposed that MHLW review the new FOSHU rules, but the government turned down the request. Therefore, the standoff continues between MHLW and the industry.

Two GMPs

Good Manufacturing Practices (GMPs) is a manufacturing practice which requires a quality approach to manufacturing, forcing companies to minimize or eliminate instances of contamination, mix-ups, and errors. Since the announcement of MHLW’s GMP guidelines last February, two non-governmental organizations have started GMP certification programs. So far, a dozen manufacturers have been granted GMP certifications. As the government is not involved with GMP certification programs, JHNFA ( Japan Health Food & Nutrition Food Association) and a newly formed Japanese Institute for Health Food Standards (JIHFS), continue to certify manufacturers with different standards and programs. This will certainly create some confusion among manufacturers as to which program to choose from as they try to decide which program is right for their practices. MHLW specifies dietary supplements and functional foods as “foods” including FOSHU products and ingredients widely used in conventional foods. Implementing dietary supplement GMP, without recognizing dietary supplements by law is like posting a speed limit where there is no highway.

On The Ingredient Front

In the last couple of weeks, several online shops announced their top selling nutraceutical products in 2005. Among the top items are: alpha lipoic acid ( ALA), CoQ10, aojiru, (green juice) and kanten, an agar gel food made from a reddish seaweed called tengusa. Kanten is a popular food for weight control and diet. Japanese people have been eating Kanten for over 150 years - often in the summer to help escape the heat. Only recently has it become a popular diet food as it has almost no calories and it fills the stomach to suppress the appetite. Kanten has no taste, but by adding fruits or other flavors it can resemble Jell-O®. Its portion control packaging also helps consumers control their weight. It is not only the number one diet food but also the most popular nutraceutical product in Japan according to Kenkocom (www.kenko.com), an Internet nutraceutical merchant. The estimated diet-oriented kanten market was $200 million in 2005.

I was surprised to see ALA as Kenkocom’s most popular ingredient in 2005. It is the number one dietary supplement ingredient but didn’t start out that way. In the beginning of this year, CoQ10 was the most active and popular ingredient. After TV programs focused on ALA, sales dramatically accelerated in the last 8 months of this year. ALA is known for preventing or treating age-related diseases from heart disease and stroke to diabetes and cataracts but in Japan, it is mostly used for sports, diet and cosmeceuticals. The ALA market jumped from $35 million in 2004 to $96 million at the end of 2005. Popularity may continue into the middle of 2006.

Sales of CoQ10 stopped just short of $130 million. In the beginning of this year CoQ10 was the only ingredient in the industry whose sales were growing. The high demand for the ingredient created high prices and a worldwide shortage in the beginning of this year. The situation has since been eased, and now production and demand levels are at a balanced, healthy level. Kenkocom lists CoQ10 as its number two most popular product in 2005 even though it certainly lost the momentum it had in 2004.

Aojiru, a green leaf juice, often made using kale and most recently, ashitaba, is Kencocom’s third most popular product in 2005.

Antioxidants, allergy, diabetes and digestive health are some of the well-established health benefits from taking aojiru. According to Health Industry News, the aojiru market is well over $500 million in 2005 and has grown 20 percent from a year ago. Most aojiru products are distributed through MLM and catalog sales. Toyo Shinyaku (www.toyoshinyaku.co.jp) has over 20 aojiru FOSHU products.

MSM (Methyl-Sulfonyl-Methane) sales were disappointing. We thought it would be accepted more widely but it didn’t crack the top 20.

Just as with any other consumer product, popularity changes and supplements are no exception. Japan’s notoriously finicky shoppers are always looking for something new. To satisfy this consumer, the Japanese manufactures are always looking for what’s next.

What will be the hot ingredients in 2006? Again, here are some of kenkocom’s predictions for ingredient trends in 2006:

Amino acids like, ornithine, creatine and glutathione are effective for diet, energy and cosmeceuticals and they are one of the more promising ingredients for 2006. Biotin, enzyme and astaxanthin are also among the expected popular products in 2006. See more detail at: (www.e-expo.net/news/2005/1212_04.html)

...

I would like to take this opportunity to thank you for your support, and to wish you a happy and healthy new year.
Paul Yamaguchi is president of Paul Yamaguchi & Associates, Inc., Tarrytown, NY.
His company publishes a number of Japanese nutrition market reports. His latest report is Nutritional Supplement Japan 2005, Inside of $11.1 billion Japanese dietary supplement market. Other report is Functional Foods and FOSHU Japan 2004, Market & Product Report.

For details and information on the reports, visit: http://www.functionalfoodsjapan.com/ or contact Paul at pya@ix.netcom.com

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http://www.npicenter.com/anm/templates/newsATemp.aspx?articleid=14541&zoneid=45

Mark said...

Ideally, medicine would be mostly a form of remediation.

Mark said...

Aojiru—Can a glass of tree kale a day keep the doctor away?

photography by Tomoyasu Naruse

The morning ritual

It is a cold afternoon in December. The tree kale in the garden of Dr. Jiro Endo, former director of Shimane Medical University Hospital and the foremost authority on aojiru (green juice) for health, stands nearly 150 centimeters high. It is full of dark green, succulent leaves. Around it grow some 20 other seasonal vegetables—komatsuna (Brassica rapa var. pervidis), Welsh onions, daikon radish—all looking good enough to pluck and eat on the spot. The doctor mulches his garden with dried leaves and straw to insulate it from the cold; he does not, however, use any chemical fertilizers. He inherited the garden from his father, Niro, also a medical doctor, who began growing vegetables here about 40 years ago for his own research. Each morning, Jiro ritualistically picks 10 leaves of kale, from which he extracts and drinks 90 milliliters of fresh aojiru. Today he picks and runs several dozen leaves through his juice extractor to make aojiru for Kateigaho reporters.

"It's delicious!" we all blurt out in unison after the first sip.

A member of the cabbage family, tree kale has leaves that are slightly larger than a sheet of notebook paper and after assimilating the benefits of sun, earth, and water, they grow quite thick. We recall feeling as if each fresh drop, concentratedly sweet and bitter in taste, was permeating every cell in our bodies.

Aojiru The bright green cocktail contains not a drop of water, only 100-percent kale-leaf juice.

A member of the cabbage family, tree kale is native to Southern Europe where it is commonly cooked with other ingredients. A full-grown leaf is slightly larger than a sheet of notebook paper. In 1954 Dr. Niro Endo published his first book (left) documenting the effectiveness of aojiru on human health. He produced 40 books and research papers on the subject. Born in 1900, he lived to the age of 92, a real "aojiru life."

The aojiru craze
The aojiru market has grown proportionally with Japan's increasing health consciousness, and now stands at around 50 billion yen. With some 150 to 200 companies making aojiru, ranging from handmade varieties to mass production by major manufacturers, there are now countless beverages boasting the name "aojiru."

Why has aojiru reached this extraordinary level of popularity in Japan? Not only does it contain the highly nutritious elements found in kale (including some 40 vitamins, minerals, and other nutrients), but these nutrients exist in almost perfect balance. With new medical evidence demonstrating the positive effects of drinking raw kale juice on a daily basis, aojiru has been dubbed a miracle drink.

Among vitamins, kale is rich in vitamins A, B1, B2, C, E, and K. Compared to cabbage, which has always been considered a nutritious vegetable, kale is 58 times higher in vitamin A, one and a half times higher in B1, five times higher in B2, twice as high in C, 24 times higher in E, and two and a half times higher in vitamin K. As for minerals, kale has three to five times more calcium and iron than cabbage, and one and a half to three times more sodium, magnesium, and potassium. Kale is also high in fiber, which supports the functions of the colon; anti-cancer flavonoids and MSM (essential mineral sulfur); anti-oxidants, which prevent aging and lifestyle-related illnesses; polysaccharides and polyphenols, used to treat allergies; and has twice the calcium—an immunity booster—of milk.

Aojiru is of course low in sugars, protein, and fat, so regardless how much you drink, there's little fear of gaining weight. And as is obvious from its vivid green color, aojiru is rich in chlorophyll, which purifies and lowers the viscosity of the blood. The positive effects of aojiru are too numerous to list: indeed, drinking it is an ideal way to stay healthy today. Still, the full extent of aojiru's health benefits remains unknown. Private companies, universities, and medical centers are now collaborating to learn more.

Leafy green benefits
In 1983 the owner of a food-delivery company called Q'SAI suffered a stroke, but after regularly drinking aojiru made a full recovery. The experience soon launched Q'SAI into the aojiru business, and today nearly 30 percent of the company's sales come from vegetable juice. In 2003 Q'SAI presented joint research conducted with Yamaguchi Prefectural University confirming that aojiru suppresses the metastasis of cancer cells. It also worked with Kyushu University to show that aojiru promotes the excretion of environmental contaminants such as dioxins and PCBs.

Cosmetics manufacturer Fancl entered the aojiru market in 2000, expanding it from what until then had been limited to the health-conscious older generation to women in their 20s and 30s. Fancl's joint research with Kyushu University went on to link aojiru with stimulating serotonin in the brain, perhaps making it effective in the treatment and prevention of depression and insomnia.

Jiro and Niro
It's easy to understand the growing expectations of aojiru. What's hard to believe is that aojiru originated as a remedy for malnourishment when food was scarce during and after World War II. Jiro's father Niro conceived of aojiru in October 1943, when people were forced to live on scant rations and grapple with the realities of hunger. The discarded tops of daikon radishes in the fields near his home caught Niro's eye, and prompted him to collect the discarded leaves not only of daikon, but of soybean, sweet potato, eggplant, and other plants to feed his family. After seeing a distinct improvement in their health, he began researching leafy green foods.

The following year Jiro, who had just entered junior high, came down with pneumonia. Naturally there was no penicillin, and desperate to do something to treat his son, Niro extracted and fed him the juice from mitsuba (Japanese parsley) he picked every day around their home, upon which Jiro made a speedy recovery. Shortly thereafter Niro's wife suffered acute nephritis, a fatal disease for which modern medicine had yet to find an effective cure. Within two to three months of feeding her a therapeutic diet centered on aojiru, she recovered. Hence the illnesses the Endo family suffered during the war gave rise to aojiru, and having witnessed its efficacy, Niro subsequently devoted himself to its research. As an army doctor, amid shortages of medical supplies in the field, he extracted aojiru from wild plants, and at the last hospital he headed before retirement he made aojiru for his patients. It worked like a charm and was eventually integrated into hospital meals. In 1949 Niro discovered kale, which ultimately became popular nationwide and was even introduced into school lunches.

The miracle cabbage
"Before kale, procuring enough fresh green vegetables to make aojiru year-round was no easy task," recalls Jiro. "My father discovered it in a gardening book: it could be grown 12 months a year and had extraordinary nutritional balance. Father had seeds sent from the U.S. and started growing it in our garden."

Thus, kale became the main ingredient of aojiru and soon surpassed all other vegetables as "the miracle green." Ironically, Niro later discovered writings on kale in the Ishinho, Japan's oldest medical work completed over 1,000 years ago, and the Ming-dynasty encyclopedia of Chinese medicine, Bencao Gangmu (Compendium of Materia Medica). Despite its having disappeared from Japan, Niro managed to revive kale domestically in the healthiest of forms.

While aojiru has now come into its own, it didn't grow into a phenomenon overnight. Initially, there was great resistance among doctors and health professionals because of its departure from Western medical practices. It has taken the hard work and devoted efforts of father and son spanning two generations to promote aojiru and contribute to its current market of 50 billion yen.

What impressed us most in researching this article, however, was to learn that the father of aojiru, the man who fostered this unlikely drink and gave it its name, never received a penny from the business: "Father only wanted more people to be healthy," says Jiro. "We were just fulfilling our mission as doctors."

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http://int.kateigaho.com/spr05/tea-aojiru.html

Mark said...

Should you go on the market for zeolite, you should read this on the inadequacy of liquid zeolite:
http://www.zeohealth.com/LIQUIDZEOLITEresponse.pdf

Though on the contrary, the homeopathic doctor above reports success from liquid zeolite. You decide.

Mark said...

Research Backs Theory Vit C Shrinks Tumors

By Jeremy Laurance, Health Editor
Tuesday, 28 March 2006

New research suggesting that vitamin C can be effective in curing cancer will renew interest in the "alternative" treatment for the terminal disease.

Three cancer patients who were given large intravenous doses over a period of several months had their lives extended and their tumours shrunk, doctors reported yesterday.

A 49-year-old man diagnosed with terminal bladder cancer in 1996 was still alive and cancer-free nine years later, having declined chemotherapy and radiotherapy in favour of regular infusions of vitamin C.

A 66-year-old woman with an aggressive lymphoma who had a "dismal prognosis" in 1995 was similarly treated and is still alive 10 years later. A 51-year-old woman with kidney cancer that spread to her lungs diagnosed in 1995 had a normal chest X-ray two years later. The findings were confirmed by pathologists. Although they do not prove the vitamin cured the cancer they do increase the "clinical plausibility" of the idea, the researchers say.

Vitamin C therapy was first promoted by Linus Pauling, the Nobel prize winner, 30 years ago. Dr Pauling's claims sparked the continuing boom in sales of vitamin C, but attempts to confirm his findings failed and high-dose vitamin C became an "alternative" therapy.

The latest study, published in the Canadian Association's Medical Journal, could trigger renewed interest in Dr Pauling's claims. Studies show that vitamin C is toxic to some cancer cells but not to normal cells. The problem has been delivering a high enough dose.

The researchers say attempts to replicate Dr Pauling's work failed because they used oral doses of the drug which is rapidly excreted. However, injections achieve blood levels 25 times higher that persist for longer. At these very high doses, the blood level of vitamin C is high enough to selectively kill cancer cells.

Several clinical trials of vitamin C therapy are about to start, including one at McGill University, Montreal, the authors say.

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http://www.independent.co.uk/life-style/health-and-wellbeing/health-news/research-backs-theory-that-vitamin-c-shrinks-tumours-471757.html

Mark said...

Vitamin Deficiency May Cause Many Diseases

By Steve Connor
Saturday, 16 February 2008

A chronic shortage of vitamins and other "micronutrients" in the diet may be responsible for triggering many of the ills of modern life such as cancer, obesity and the degenerative diseases of ageing.

Professor Bruce Ames, of the University of California, Berkeley, who invented one of the standard tests for cancer-causing chemicals, said many people's diets were deficient in one or more of the 40 micronutrients essential for a healthy life.

Taking dietary supplements in the form of vitamin pills could help to counteract many of the disorders associated with ageing, Dr Ames told the American Association meeting.

He said many people on a high-calorie diet in the West or poor diet in developing countries were short of micronutrients and this caused the body to go into an emergency "triage" response in which it tried to keep its metabolism in balance by a process of compensation. This ensures immediate survival, but the consequences are an increase in DNA damage, which causes future cancers, a lowered immune defence, and a decay of the mitochondrial "power plants" of the cells, which causes accelerated ageing," he said.

He said a shortage of minerals, vitamins and other nutrients could also be partly responsible for obesity.

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http://www.independent.co.uk/life-style/health-and-wellbeing/health-news/vitamin-deficiency-may-cause-modern-ills-782990.html

Mark said...

Requiem for Royal Rife [curing cancer 100%, with different frequencies, a buried solution in medicine because of other raw material regimes' political power to stop it--the medical industries and the optical glass industries (that would be outclassed in methods for optics that Rife pioneered).]

The Hubbard Interviews: Introduction
Searching For A Lost Way of Looking At Things
By Shawn Montgomery
8-10-6

Have you heard this crazy story?

An eccentric genius in depression-era California invented several fantastic medical devices including super microscopes and a death ray for microbes. In a twenty-year research initiative costing millions of dollars and backed by the most prestigious men in medical science, this genius endeavored to deliver the "cure for cancer" to the world. By 1934, he had discovered a virus in cancer tumors and developed a way to destroy that virus with a beam of electrical energy produced by his invention: the Beam Ray Machine. Human clinical trials were set up and presided over by top-of-their-field doctors who were to discover that the "cure" was one hundred percent effective, with terminal patients enjoying full recoveries. Then, the AMA stepped in and, using nefarious means, shut down the whole endeavor. The cure for cancer was denied to the world because it was not pharmaceutically based and therefore not profitable to drug companies.
The End

Isn't that the craziest thing you have ever heard?

This story actually floated around as rumor for several decades following World War Two. Lacking any corroborative evidence, telling details, or historical presence, it resisted being taken seriously as a "true story." A tad too apocryphal. Surely allegorical. A tale easily dismissed is one with no apparent record.

In the early 1970's, journalist Christopher Bird did some digging. He'd heard this story and wanted to settle its veracity once and for all. It didn't take long for him to find what was probably the source for at least part of the rumor. Bird had found a stunning article printed in two 1944 science journals: The Journal of the Smithsonian Institute and the Journal of the Franklin Institute. The article, titled "The New Microscopes," gave a detailed account of the work of the eccentric genius in the crazy story. Working from there, and digging deeper, journalist Bird was able to finally determine that the crazy story is actually true. He soon published in the New Age Journal an article titled "What Has Become of the Rife Microscope?" ­ It was the saga of Royal Raymond Rife: the eccentric inventor who cured cancer.

Today it is a simple matter to do an internet search on "Royal Raymond Rife" and have delivered to your computer a wealth of information on history's most forgotten scientist. You'll find not just the "New Microscopes" article from the Smithsonian Journal and Bird's article from the New Age Journal, but as well a wealth of corroborative data: dozens of newspaper and science journal articles, hundreds of personal letters between the doctors involved, photographs of Rife's scopes and other inventions, schematics, lab notes, lab films, reports, interviews, documentaries, books - the story of Rife is a rumor no more and his remarkable achievements seem not to be forgotten.

A once-suppressed science released from a veil of obscurity would be a glorious thing, especially a potential cure for cancer - but in the case of Rife, the glory is somewhat diminished. Though many details of his contributions survive as documentary evidence: pictures, films, schematics, testimony, reports and so forth - the real treasure would be actual surviving operational Rife Microscopes, Beam Ray Machines, or other artifacts. Even today the location and condition of many of Rife's inventions remains largely uncertain. Thirty years ago it was not much different even though the trail was much warmer. The documents that attest to the reality of these things were in hand, so where were these things?

It was in the mid-1940's that a young student of pathology first became obsessed with the Rife Universal Microscope. John Hubbard, keeping up with current advancements in the tools of his chosen field, was thumbing through the above-mentioned Journal of the Smithsonian Institute when he came upon the article titled "The New Microscopes." In astonishment, he read of Rife's instrument - a microscope that appeared to defy the accepted limits of optics. At face value the text of the article seemed somewhat incredible. However, three photomicrographs included therein, taken through the Universal Microscope, tempered Hubbard's incredulity. The published photos were all labeled with magnification values: Chlorophyll (Cell) 17,000X; Tetanus (Spore) 25,000X Typhoid Bacillus (B. Typhosus) 23,000X. Hubbard recognized the extraordinary features of the pictures: the uncanny resolution of detail; the fantastic magnification values (one order higher than standard optical scopes); the clear imaging of certain structural features within the specimens (the existence of which had previously only been suspected by microbiologists - never seen and confirmed). Here it was: the ultimate microscope. A tool that could crack open the still-murky world of germs and spill all of the remaining secrets out onto the table. A tool that could help to answer just about any question a microbiologist could ask. Hubbard was duly impressed. In his mind, the near-anomalous-looking photos confirmed the story. This was one microscope he wanted to have. Reading about it was one thing, but actually working with such a scope in one's lab would elevate any microbiologist onto a whole new level.

So he began following up in earnest. He sent letters to everyone he could think of: the Royal Rife in the article of course, it's authors, and any other names or places mentioned in the text. He sent letters to all optical companies: Leitz, Zeiss, American Optical etc... asking if they had any info on this microscope. Unfortunately, it was a fruitless effort. Most of the correspondence went unanswered ­ nobody seemed to know anything about it and those that surely did weren't talking. The microscope and its inventor remained elusive to the young Hubbard.

Almost thirty years later, the inquisitive young student had matured into a tenured Professor of Pathology at New York University in Buffalo. It was in the mid-1970's that Professor Hubbard serendipitously regained the scent from a long lost trail. He happened upon Christopher Bird's article while browsing a magazine rack. Hubbard's fascination with Rife and his super-microscopes had not abated, but Bird's article acted as an accelerant. Armed with new information, the Professor was on the hunt again. He contacted Christopher Bird, who was himself still immersed in his own quest for Rife artifacts while following-up on his own article. In fact, Bird had located the estate of the recently deceased Rife and was in contact with his heir: one John F. Crane, a mechanical engineer from San Diego. By lucky coincidence, Bird was looking for an expert in microscopy and pathology to help him assess the instruments that Crane said were in his possession. Their quests merged and soon Hubbard and Bird were working together in an investigative capacity, determined to unearth, examine, and if possible, obtain a Rife Microscope (to satisfy Hubbard) and a Beam Ray Machine (to satisfy Bird)... and, the WHOLE story on this crazy Rife affair, (to satisfy both of them). They didn't know it at the time, but what Hubbard and Bird did in their initial united effort was pioneer a field of endeavor that would, in decades, become something quite labyrinthine - involving thousands of people. They invented modern Rife Research. John Hubbard and Christopher Bird were the first (post) Rife Researchers. Their mission: reestablish the technology, methodology, and discipline that led Rife to his recorded successes.

From John Crane they obtained a list of about a dozen names with some contact information: people who were still alive that knew or worked with Rife. They went to San Diego, Chicago, England, and Los Angeles, anywhere that the information led. It was an interview process that lasted years, predominantly conducted by Professor Hubbard, and one which, thankfully, he recorded. Ultimately, Hubbard's quest turned into a long, protracted negotiation with John Crane to get him to release the microscopes over to the University of New York for study on purely academic grounds. He was simultaneously trying to marshal the services of a group of men who had actually worked with Rife on the same microscopes in an effort to assemble a reconstructionist team to bring the intricate instruments back into working order. Hubbard had discovered that John Crane was the owner of the lion's share of Rife's surviving "stuff." In fact, he said that Crane was, "the most terrifically awful curator of scientific instruments imaginable." When he arrived at John Crane's house in San Diego to finally set eyes on the precious scientific treasure that he had been dreaming of for decades, he found it to be in "near ruins," surrounded by "disarray and clutter," with a "disheveled and unhealthy-looking" Crane oddly unaware of his glaring ineptness as a guardian, but fully aware of the history, value and importance of the artifacts that cluttered his place.

I met Professor Hubbard in 1996. A few years prior I had become one of those so-called "Rife Researchers." I had seen his name cropping up from time to time among the pages of a rather voluminous pile of my own accumulated "Rife documents" - a stack which cost many years and dollars - compiled with the help of my friend and fellow Rife Researcher, Jason Ringas. We traveled to Buffalo to meet with the Professor, talk shop, and to share information and documents. The most notable item in his data collection were his forty hours of recorded audio interviews with various people who knew and worked with Rife. Hubbard allowed us to make copies of these (then) twenty-year-old recordings. I took the copies home with me and transcribed them.

Ten years later it's 2006 and everyone that was involved in that early research/resurrection effort is dead. John Hubbard died the year before last. Chris Bird died ten years ago. John Crane died in 1995. Rife of course died before all these people met. Everyone who Hubbard and Bird interviewed were old men thirty years ago when the interviews took place. Therefore, in the interest of not letting their voices die with them, Jeff Rense has agreed that it is time to let these people speak again and has allowed his website to platform their discussions.

The Hubbard Interviews

The following people were interviewed by Professor Hubbard (1976 ­ 1979):

Ben Cullen ­ Rife's lab assistant and friend for over 30 years.
Henry Siner ­ Rife's microscope assistant and friend for 15 years.
Bertrand Comparet - Rife's attorney. Defended the famous Beam Ray Trial for Rife in 1939 and the infamous Crane/Marsh trial in 1962.
Robert Page ­ Rife's young neighbor, friend and confidant. Later he patented a microscope illumination system based on Rife's design.`
Dr. Henry ­ Visited Rife in conference. Surveyed his lab.
Dr. Renner ­ Visited Rife in conference. Surveyed his lab.
Bernard Gross ­ Employed Rife in later years.
Dr. Seidel ­ Co-wrote "The New Microscopes" for The Franklin Journal (1944).
John Crane ­ Met Rife in 1950 and knew him/worked with him/exploited him for the rest of his days.
Hubbard also interviewed a host of Professors, optics technicians, lens experts and other professionals (who did not know Rife personally).

We'll start with Robert Page because he touches upon some important themes that are familiar to Rense readers.

http://www.rense.com/general73/p1.htm
http://www.rense.com/general76/rfn.htm

Edwina said...

I believe u havent read a single clinical trial about that compound. I happen to work on plants at my university and your clains are ridiculous. u can say i was expecting thaqt claim but with PUBMED available for everyone, if not the entire article, the abstract is available, it only takes me a few seconds to debunk your theory.

Mark said...

What "compound" are you talking about. I'm curious. I've mentioned several interesting things above in this string of 40 comments!

What you wrote doesn't talk specifics or reference what comment you are talking about, so you don't really add to the discussion so far.

If you check back, you are invited to post something more specific to contribute. (Punctuation, spelling, and grammar standards requested as well. If you want to communicate well, well, learn to communicate.)

Mark said...

http://www.npr.org/templates/story/story.php?storyId=88123868&ft=1&f=1001

Stem-Cell Therapy in China Draws Foreign Patients

by Louisa Lim
http://www.npr.org/templates/story/story.php?storyId=88123868&ft=1&f=1001

Jena Teague and Terry Williams brought their 7-month old baby Laylah to China for treatment.
Louisa Lim, NPR

Jena Teague and Terry Williams brought their blind, 7-month-old baby Laylah to China for an experimental stem-cell treatment. Laylah has optic nerve hypoplasia, an incurable condition. Chinese doctors say they see signs her therapy is working.

Other Possible Treatments

Some U.S. experts say there's no evidence that the stem cell therapy being offered in China will work in one of the most common causes of childhood blindness, optic nerve hypoplasia (ONH).

Dr. Mark Borchert, head of the vision center at Children's Hospital Los Angeles, weighs in on the debate and possible treatments.

Read that story.

Morning Edition, March 18, 2008 · China is gaining popularity among a new breed of travelers: patients with incurable conditions who are visiting the country to receive experimental stem-cell treatments not offered in the United States.

One company is now claiming a medical breakthrough, advertising that its treatments are restoring vision to blind children. It has ignited a firestorm of controversy in both China and in the U.S.

Giving Parents a New Option

Jena Teague and her husband Terry Williams are among these new visitors. They traveled to China to seek stem-cell treatment for their blind, 7-month-old baby daughter, Laylah. She was born with optic nerve hypoplasia, or ONH — when the optic nerves fail to develop properly in the womb. Conventional medicine offers no treatment and no cure.

But Teague came across a Web site about stem-cell treatments offered by Beike Biotechnology in China and decided to try it — against advice from specialists at home in Georgia.

"None of the specialists had heard of the stem cells, of what they're doing here. They didn't believe it would work. They told me not to expect anything to happen out of it," Teague says.

Nonetheless, the family traveled to the eastern Chinese city of Hangzhou, where Beike is based. They are spending $23,000 for Laylah to have infusions of stem cells harvested from umbilical cords — not the more controversial embryonic stem cells. In the U.S., cord blood stem cells are used for treating blood diseases, but are not used for treating other conditions, such as Laylah's vision problem.

Treatment Seems to Yield Positive Results

After three sessions, Teague and Williams say the therapy is already working.

The doctors have told Laylah's parents that the baby now sees light through one eye, while the other eye is dilating almost to the point where she can see light.

So far, 10 patients suffering from ONH have received the same stem-cell treatment in China, and doctors there claim that the vision of all 10 improved after the therapy.

At age 5, Rylea Barlett also received the stem-cell treatment. She, too, had been blind before.

Dr. Shalesh Kaushal, an eye specialist at the University of Florida, examined Bartlett, who is now 6, after she returned to the U.S.

"This child had essentially no light perception, and upon returning she's had a gradual improvement — so much so that at our exam it appeared that she had formed vision," he says. "That is to say that she could at least recognize large letters."

Kaushal concluded that the stem-cell therapy was the only clinical explanation for her improvement. Some infants with ONH gain more vision spontaneously over the first few years of life, but Barlett was already too old for that.

Kaushal is now evaluating other patients before and after the stem-cell treatment. But he is not recommending that patients go to China; he says much more research needs to be done.

"It's clearly a provocative result. … If this is a real, reproducible observation or effect in other patients, one may consider it as a fundamental breakthrough," says Kaushal.

Reasons for Improvements Remain a Mystery

Dr. Sean Hu, the 40-year-old chairman of Beike Biotechnology, is a medical doctor-turned-entrepreneur with a doctorate in biochemistry from a Swedish university.

Less than three years ago, he set up Beike. Since then, 3,000 patients — most of them from China — have received Beike's stem-cell treatments for a wide range of conditions. He says 70 percent have seen improvements, but he admits he can't explain why.

"In the clinical areas, we know there are improvements. We don't know the mechanism behind it," Hu says.

That raises many concerns. Any improvement could be due to the placebo effect — or other factors besides the stem-cell therapy — and may not lead to longer-term functional gains. No rigorous, controlled clinical trials were carried out before the treatment was offered to patients. No research has yet been published in established peer-review journals overseas. And no one knows for sure what the possible risks might be.

But Hu isn't worried by the ethical implications of what he's doing.

"I can say I changed the life of these patients. Now they get their vision back. They went from completely blind, now they can see stuff. You think that's ethical or nonethical?" he asks.

Therapies Criticized as 'Extreme Nonsense'

Beike claims to treat a wide range of conditions with stem-cell therapy — from spinal-cord injuries to epilepsy to cerebral palsy to neurodegenerative disorders. But critics have their doubts.

Bruce Dobkin is director of the neurologic rehabilitation and research program at the University of California, Los Angles. In response to questions from NPR, he writes in an e-mail that "it is extreme nonsense to think that cells can be incorporated into the complex nervous system and do so much, when we cannot even get cells in mice and rats to do very much."

Chinese scientists are worried, too.

Dr. Naihe Jing is the deputy director of one of China's top stem-cell research labs and a member of the prestigious Chinese Academy of Sciences. He fears Beike could ruin the reputation of China's entire biotech industry.

"We think money is mainly behind this," he says, adding that he is concerned that one company's pursuit of profit will create a bad reputation for the whole country.

Providing Help, Providing Hope

Already, 600 foreigners have come to China and paid about $20,000 each for the stem-cell therapy, while even more Chinese patients are flocking for treatment.

The venture capital is flooding in, too. Hu, Beike's chairman, says he has raised about $15 million in funding, although NPR could not verify the claim. He admits making a calculated decision to go into stem-cell research: As he puts it, you have to choose the area with the best return.

"Obviously, [stem-cell research] is the most important area in biotech research in the future, because it's going to create a huge market, even bigger than the whole pharmaceutical industry. Stem-cell and regenerative medicine is the future of medicine," Hu says.

And parents continue to bring their children to Beike in the hopes of finding a cure for their ailments.

The results of Beike's experimental therapy may be uneven and unproven. Yet for patients and their families, hope is, perhaps, the most important commodity on sale in China — even if it costs tens of thousands of dollars.

---
http://www.npr.org/templates/story/story.php?storyId=881238

Mark said...

French Volcanic Clay Kills Antibiotic-Resistant MRSA Superbug
by David Gutierrez

(NaturalNews) Researchers have discovered that a clay made from volcanic ash in France has powerful antibiotic properties and is capable of killing even antibiotic-resistant superbugs such as methicillin-resistant Staphylococcus aureus (MRSA).

"It's fascinating," said researcher Shelley Haydel, a microbiologist at Arizona State University. "Here we are bridging geology, microbiology, cell biology. A year ago, I'd look at the clay and say, 'Well, that's dirt.'"

MRSA is an antibiotic-resistant variety of the common bacteria that causes staph infections. This makes it more likely to develop potentially fatal complications, as it can proceed untreated for longer and spreads rapidly in institutional settings such as hospitals, prisons and schools.

Researchers added the volcanic clay, called agricur, to cell colonies of MRSA, and found that 99 percent of colonies were eliminated within 24 hours. In the same time period, colonies not treated with the clay grew by 45 percent.

The clay exhibited similar antibiotic effects against salmonella, E. coli and buruli.

Buruli is a flesh-eating relative of leprosy that causes disfigurement of children.

Due to its prevalence in Africa, the World Health Organization has classified it as "an emerging public health threat."

The researchers do not yet know what about the clay is responsible for its antibiotic properties.

While clay has a history as a folk remedy for nausea and a spa treatment, the former use has not been seriously studied and the latter is due to clay's ability to hold heat and draw out toxins.

"We have multiple working hypotheses," to explain the properties of antibacterial clay, researcher Lynda Williams said. "Our primary hypothesis is that the clay minerals transfer elements, not yet identified, to the bacteria that impede their metabolic function. It is entirely possible that it is not one single element that is toxic to the bacteria, but a combination of elements and chemical conditions that attack the bacteria from different angles so as to overwhelm their defense systems."

While unlikely, it is also possible that the clay kills bacteria through physical rather than chemical processes, which would make it incredibly difficult for the bacteria to develop resistance to it.

---
http://www.naturalnews.com/z023022.html

Mark said...

A Magnesium Deficiency Increases Cancer Risk Significantly
by Mark Sircus Ac., OMD (see all articles by this author)


(NaturalNews) There is a power and a force in magnesium that cannot be equaled anywhere else in the world of medicine. There is no substitute for magnesium in human physiology; nothing comes even close to it in terms of its effect on overall cell physiology.

Without sufficient magnesium, the body accumulates toxins and acid residues, degenerates rapidly, and ages prematurely. It goes against a gale wind of medical science to ignore magnesium chloride used transdermally in the treatment of any chronic or acute disorder, especially cancer.

Magnesium repletion produced rapid disappearance of the periosteal tumors.

Aleksandrowicz et al in Poland conclude that inadequacy of Mg (Magnesium) and antioxidants are important risk factors in predisposing to leukemias.

Other researchers found that 46% of the patients admitted to an ICU (Intensive Care Unit) in a tertiary cancer center presented hypomagnesemia.

They concluded that the incidence of hypomagnesemia in critically ill cancer patients is high. In animal studies we find that Mg deficiency has caused lymphopoietic neoplasms in young rats. A study of rats surviving Mg deficiency sufficient to cause death in convulsions during early infancy in some, and cardiorenal lesions weeks later in others, disclosed that some of survivors had thymic nodules or lymphosarcoma.

One would not normally think that Magnesium (Mg) deficiency can paradoxically increase the risk of, or protect against cancer yet we will find that just as severe dehydration or asphyxiation can cause death, magnesium deficiency can directly lead to cancer.

When you consider that over 300 enzymes and ion transport require magnesium and that its role in fatty acid and phospholipid acid metabolism affects permeability and stability of membranes, we can see that magnesium deficiency would lead to physiological decline in cells setting the stage for cancer. Anything that weakens cell physiology will lead to the infections that surround and penetrate tumor tissues. These infections are proving to be an integral part of cancer. Magnesium deficiency poses a direct threat to the health of our cells. Without sufficient amounts, our cells calcify and rot in. Breeding grounds for yeast and fungi colonies they become, invaders all too ready to strangle our life force and kill us.

Over 300 different enzymes systems rely upon magnesium to facilitate their catalytic action, including ATP metabolism, creatine-kinase activation, adenylate-cyclase, and sodium-potassium-ATPase.

It is known that carcinogenesis induces magnesium distribution disturbances, which cause magnesium mobilization through blood cells and magnesium depletion in non-neoplastic tissues. Magnesium deficiency seems to be carcinogenic, and in case of solid tumors, a high level of supplemented magnesium inhibits carcinogenesis. Both carcinogenesis and magnesium deficiency increase the plasma membrane permeability and fluidity. Scientists have in fact found out that there is much less Mg++ binding to membrane phospholipids of cancer cells, than to normal cell membranes.

Magnesium protects cells from aluminum, mercury, lead, cadmium, beryllium and nickel.

Magnesium in general is essential for the survival of our cells but takes on further importance in the age of toxicity where our bodies are being bombarded on a daily basis with heavy metals. Glutathione requires magnesium for its synthesis. Glutathione synthetase requires y-glutamyl cysteine, glycine, ATP, and magnesium ions to form glutathione. In magnesium deficiency, the enzyme y-glutamyl transpeptidase is lowered. According to Dr. Russell Blaylock, low magnesium is associated with dramatic increases in free radical generation as well as glutathione depletion and this is vital since glutathione is one of the few antioxidant molecules known to neutralize mercury. Without the cleaning and chelating work of glutathione (magnesium), cells begin to decay as cellular filth and heavy metals accumulate; excellent environments to attract deadly infection/cancer.

There is drastic change in ionic flux from the outer and inner cell membranes both in the impaired
membranes of cancer, and in Mg deficiency.

Anghileri et al proposed that modifications of cell membranes are principal triggering factors in cell transformation leading to cancer. Using cells from induced cancers, they found that there is much less magnesium binding to membrane phospholipids of cancer cells, than to normal cell membranes. It has been suggested that Mg deficiency may trigger carcinogenesis by increasing membrane permeability. Magnesium deficient cell membranes seem to have a smoother surface than normal, and decreased membrane viscosity, analogous to changes in human leukemia cells. There is drastic change in ionic flux from the outer and inner cell membranes (higher Ca and Na; lower Mg and K levels), both in the impaired membranes of cancer, and of Mg deficiency. And we find that lead (Pb) salts are more leukemogenic when given to Mg deficient rats, than when they are given to Mg-adequate rats, suggesting that Mg is protective.

Magnesium has an effect on a variety of cell membranes through a process involving calcium channels and ion transport mechanisms. Magnesium is responsible for the maintenance of the trans-membrane gradients of sodium and potassium.

Long ago, researchers postulated that magnesium supplementation of those who are Mg deficient, like chronic alcoholics, might decrease emergence of malignancies and now modern researchers have found that all types of alcohol -- wine, beer or liquor -- add equally to the risk of developing breast cancer in women. The researchers, led by Dr. Arthur Klatsky of the Kaiser Permanente Medical Care Program in Oakland, Calif., revealed their findings at a meeting of the European Cancer Organization in Barcelona in late 2007. It was found that women who had one or two drinks a day increased their risk of developing breast cancer by 10 percent. Women who had more than three drinks a day raised their risk by 30 percent. The more one drinks, the more one drives down magnesium levels.

Breast cancer is the second most common cancer killer of women, after lung cancer. It will be diagnosed in 1.2 million people globally this year and will kill 500,000.

According to data published in the British Journal of Cancer in 2002, 4 percent of all breast cancers -- about 44,000 cases a year -- in the United Kingdom are due to alcohol consumption. It's an important question though, and one not asked by medical or health officials, is it the alcohol itself or the resultant drop in magnesium levels that is cancer provoking? Though some studies have shown that light to moderate alcohol use can protect against heart attacks, it does us no good to drink if it causes cancer. Perhaps if magnesium was supplemented in women drinkers who were studied, there would have been no increase of cancer from drinking.

Alcohol has always been known to deplete magnesium, and is one of the first supplements given to alcoholics when they stop and attempt to detoxify and withdraw.

Researchers from the School of Public Health at the University of Minnesota have just concluded that diets rich in magnesium reduced the occurrence of colon cancer. A previous study from Sweden reported that women with the highest magnesium intake had a 40 per cent lower risk of developing the cancer than those with the lowest intake of the mineral.

Pretreatment hypomagnesemia has been reported in young leukemic children, 78% of whom have histories
of anorexia, and have excessive gut and urinary losses of Mg.

Several studies have shown an increased cancer rate in regions with low magnesium levels in soil and drinking water, and the same for selenium. In Egypt, the cancer rate was only about 10% of that in Europe and America. In the rural fellah, it was practically non-existent. The main difference was an extremely high magnesium intake of 2.5 to 3g in these cancer-free populations, ten times more than in most western countries.

The School of Public Health at the Kaohsiung Medical College in Taiwan found that magnesium also exerts a protective effect against gastric cancer, but only for the group with the highest levels.

If we looked, it would probably be very difficult to find a cancer patient with anywhere near normal levels of cellular magnesium; meaning cancer probably does not exist in a physical cellular environment full of magnesium. It makes perfect medical sense to saturate the body with magnesium through transdermal means. Magnesium deficiency has been implicated in a host of clinical disorders but the medical establishment just cannot get it through its thick skull that it is an important medicine.

It is as if the collective medical profession had just pulled the plug on medical intelligence. In fact it has done exactly this and it seems too late for it to redefine itself, which is a tragedy. Though magnesium improves the internal production of defensive substances, such as antibodies and considerably improves the operational activity of white granulocytic blood cells (shown by Delbert with magnesium chloride), and contributes to many other functions that insure the integrity of cellular metabolism, no one thinks to use it in cancer as a primary treatment. It is even worse than this, the medical establishment does not even use magnesium as a secondary treatment or even use it at all and gladly uses radiation and chemo therapy, both of which force magnesium levels down further.

To not replete cellular magnesium levels would be negligent, especially in the case of cancer where a person's life is on the line. An oncologist who ignores his patient's magnesium levels would be analogous to an emergency room physician not rushing resuscitation when a person stops breathing. If one elects to have or has already had chemotherapy, they have four times the reason to pay attention to a concentrated protocol aimed at replenishing full magnesium cellular stores.

Magnesium chloride is the first and most important item in any person's cancer treatment strategy. Put in the clearest terms possible, our suggestion from the first day on the Survival Medicine Cancer Protocol is to almost drown oneself in transdermally applied magnesium chloride. It should be the first, not the last thing, we think of when it comes to cancer. It takes about three to four months to drive up cellular magnesium levels to where they should be when treated intensely transdermally but within days patients will commonly experience its life saving medical/healing effects. For many people whose bodies are starving for magnesium, the experience is not too much different than for a person coming out of a desert desperate for water. It is that basic to life, that important, that necessary.

That same power found in magnesium that will save your life in the emergency room during cardiac arrest, that will diminish damage of a stroke if administered in a timely fashion, is the same power that can save one's life if one has cancer. All a patient has to do is pour it into their baths or spray it right onto their bodies. What could be simpler?

Magnesium chloride, when applied directly to the skin, is transdermally absorbed and has an
almost immediate effect on chronic and acute pain.

Special Note on Calcium and Cancer:

Experts say excessive calcium intake may be unwise in light of recent studies showing that high amounts of the mineral may increase risk of prostate cancer. "There is reasonable evidence to suggest that calcium may play an important role in the development of prostate cancer," says Dr. Carmen Rodriguez, senior epidemiologist in the epidemiology and surveillance research department of the American Cancer Society (ACS). Rodriguez says that a 1998 Harvard School of Public Health study of 47,781 men found those consuming between 1,500 and 1,999 mg of calcium per day had about double the risk of being diagnosed with metastatic (cancer that has spread to other parts of the body) prostate cancer as those getting 500 mg per day or less. And those taking in 2,000 mg or more had over four times the risk of developing metastatic prostate cancer as those taking in less than 500 mg.

Calcium and magnesium are opposites in their effects on our body structure. As a general rule, the more rigid and inflexible our body structure is, the less calcium and the more magnesium we need.

Later in 1998, Harvard researchers published a study of dairy product intake among 526 men diagnosed with prostate cancer and 536 similar men not diagnosed with the disease. That study found a 50% increase in prostate cancer risk and a near doubling of risk of metastatic prostate cancer among men consuming high amounts of dairy products, likely due, say the researchers, to the high total amount of calcium in such a diet. The most recent Harvard study on the topic, published in October 2001, looked at dairy product intake among 20,885 men and found men consuming the most dairy products had about 32% higher risk of developing prostate cancer than those consuming the least.

The adverse effects of excessive calcium intake may include high blood calcium levels, kidney stone formation and kidney complications. Elevated calcium levels are also associated with arthritic/joint and vascular degeneration, calcification of soft tissue, hypertension and stroke, and increase in VLDL triglycerides, gastrointestinal disturbances, mood and depressive disorders, chronic fatigue, and general mineral imbalances including magnesium, zinc, iron and phosphorus. High calcium levels interfere with Vitamin D and subsequently inhibit the vitamin's cancer protective effect unless extra amounts of Vitamin D are supplemented.

Magnesium is the mineral of rejuvenation and prevents the calcification of our organs and tissues that is characteristic of the old-age related degeneration of our body.

Recommendations of magnesium to calcium ratios range from 1:2 to 1:1. For those interested in preventing cancer, one should look closely at the 1:1 camp and during the first six months of treatment, one should be looking at ten parts magnesium to one part calcium. In reality, one need not even count the ratio during the first months for the only real danger of extremely high magnesium levels comes with patients suffering from kidney failure. If one is at all concerned about their calcium intake, one should eat foods high in both calcium and magnesium like toasted sesame seeds.

Up to 30% of the energy of cells is used to pump calcium out of the cells.

Doctors who have used intravenous magnesium treatments know the benefits of peaking magnesium levels, even if only temporarily. For the cancer patient the transdermal approach combined with oral use offers the opportunity to take magnesium levels up strongly and quickly. For emergency situations, three applications a day; for urgent situations, two treatments would be indicated though one strong treatment with an ounce of a natural magnesium chloride solution spread all over the body like a sun screen is a powerful systemic treatment.

It is medical wisdom that tells us that magnesium is actually the key to the body's proper assimilation and use of calcium, as well as other important nutrients. If we consume too much calcium, without sufficient magnesium, the excess calcium is not utilized correctly and may actually become toxic, causing painful conditions in the body. Hypocalcemia is a prominent manifestation of magnesium deficiency in humans (Rude et al., 1976). Even mild degrees of magnesium depletion significantly decreases the serum calcium concentration (Fatemi et al., 1991).

Calcium requirement for men and women is lower than previously estimated.

This is an excerpt from Dr. Mark Sircus' excellent new book "Winning the War On Cancer".

Fully referenced article available at: (http://www.magnesiumforlife.com/) .

More alternative cancer information available at: (http://www.winningcancer.com/) .

About the author
Mark A. Sircus Ac., OMD, is director of the International Medical Veritas Association (IMVA)http://www.imva.info/. Dr. Sircus was trained in acupuncture and oriental medicine at the Institute of Traditional Medicine in Sante Fe, N.M., and in the School of Traditional Medicine of New England in Boston. He served at the Central Public Hospital of Pochutla, in M�xico, and was awarded the title of doctor of oriental medicine for his work. He was one of the first nationally certified acupuncturists in the United States. Dr. Sircus's IMVA is dedicated to unifying the various disciplines in medicine with the goal of creating a new dawn in healthcare.

He is particularly concerned about the effect vaccinations have on vulnerable infants and is identifying the common thread of many toxic agents that are dramatically threatening present and future generations of children. His book The Terror of Pediatric Medicine is a free e-book one can read. Dr. Sircus is a most prolific and courageous writer and one can read through hundreds of pages on his various web sites.

He has most recently released his Survival Medicine for the 21st Century compendium (2,200 page ebook) and just released the Winning the War Against Cancer book. Dr. Sircus is a pioneer in the area of natural detoxification and chelation of toxic chemicals and heavy metals. He is also a champion of the medicinal value of minerals and is fathering in a new medical approach that uses sea water and different concentrates taken from it for health and healing. Transdermal Magnesium Therapy, his first published work, offers a stunning breakthrough in medicine, an entirely new way to supplement magnesium that naturally increases DHEA levels, brings cellular magnesium levels up quickly, relieves pain, brings down blood pressure and pushes cell physiology in a positive direction. Magnesium chloride delivered transdermally brings a quick release from a broad range of conditions.
International Medical Veritas Association: http://www.imva.info/

---
http://www.naturalnews.com/z023279.html

Mark said...

Amazing Light Emission Properties Of Gold Lead To Many Applications

ScienceDaily (Dec. 4, 2000) — COLLEGE STATION - The discovery of unexpected light emission properties of gold by a Texas A&M University chemist is leading to a wide range of applications in medicine, genetics and chemistry.

John P. Fackler Jr., Distinguished Professor of Chemistry and Toxicology at Texas A&M, discovered six years ago that some gold compounds were emitting fluorescent light in a much longer time than expected.

When a chemical compound is hit by light, it gets excited, and further emits fluorescent light. Fackler discovered that the fluorescent light emitted by some gold compounds could last one million times more than usually observed.

"The light must get trapped inside the compound," says Fackler. "Then the light bursts into a glow in longer times than expected."

Fackler noticed that this fluorescence occurs when gold atoms are arranged in chains and the distance between them is 3.5 angstroms (one angstrom is one millionth of a centimeter).

"The gold compound emits fluorescence because gold atoms form linear chains and interact with each other," Fackler says.

"The distance between the atoms is very important. If it is over 3.5 angstroms, you do not get fluorescence; if you are below that value, the light changes its color."

The fluorescent light also changes its color depending on the atoms surrounding gold.

So different atoms can reveal their presence by the different colors of the fluorescent light emitted by the gold compound.

"These gold compounds have some beautiful capabilities for becoming sensors to detect the presence of small concentrations of components, because light changes its color when gold interacts with different components," Fackler says.

The light emission properties of gold can also be used to detect diseases when gold attaches to nucleic acids in cells.

"As demonstrated by Chad A. Mirkin, professor of chemistry at Northwestern University, gold clusters have been designed to probe nucleic acid structure that might be associated with a particular disease," Fackler says.

One of the most important applications of gold is its use in medical drugs. "In the early 1900s, it was found that gold compounds, particularly gold with sulfur, made people with rheumatoid arthritis feel better," Fackler says. "That led to major efforts to develop drugs that dealt with rheumatoid-like diseases."

These drugs originally were introduced in people by injection. About 15 years ago, gold drug pills became available.

"This has been a godsend for a lot of people who can just pop a few pills and get out of bed," Fackler says.

The healing properties of gold in rheumatoid arthritis patients may be due to the way gold interacts with a substance called peroxynitrite, a poison probably produced by the affected cells.

"Peroxynitrite may be the major villain in the deterioration of cells and components of bone that are associated with rheumatoid arthritis. Gold is clearly involved in the production of peroxinitrites, but the details are still under study," Fackler says.

Gold drugs are effective for only 25 percent of the patients, however.

Many patients develop allergic reactions and other conditions that prevent them from using the drugs.

Gold-based therapy, called chrysotherapy, is also used to cure patients from cancer. Scientists are developing gold drugs to be used in the treatment of prostate cancer.


"The hope is that some of these gold drugs will be as useful in prostate cancers as the platinum drugs are," Fackler says. "To this time, we have not found any that have been as successful as the platinum compounds, but there are still a lot of new compounds that have been generated with gold that may well demonstrate effective properties."

The new gold compounds discovered by Fackler are also used in chemistry. They can act as catalysts, which are intermediaries helping chemical reactions go faster and lead to new chemical products.

"Probably the most exciting applications involving gold follow from the development of brand new catalytic systems," Fackler says.

Besides all the fascination associated with gold as a sign of wealth, gold is now proving to be as fascinating for its many applications.

---
http://www.sciencedaily.com/releases/2000/12/001204071813.htm

Mark said...

Stem cells apparently cure boy's fatal disease


-----------------

This is the first time that cells from bone marrow and cord blood have been used to treat a condition that does not involve blood.

Seven months after treatment,...[it's fixing itself].


-----------------


The treatment uses umbilical and marrow cells to help develop normal skin.

Doctors say it may move his genetic disorder, recessive epidermolysis bullosa, 'off the incurable list' for other patients.

By Thomas H. Maugh II, Los Angeles Times Staff Writer

June 7, 2008

Using stem cells from umbilical cord blood and bone marrow, researchers have apparently cured a fatal genetic disease in a 2-year-old Minneapolis boy, which could open the door for other stem cell treatments.

For the first time in his life, Nate Liao is wearing normal clothes, eating food that has not been pureed, and playing with his siblings.

"Nate's quality of life is forever changed," said Dr. John Wagner of the University of Minnesota Medical School, who performed the treatment. "Maybe we can take one more disorder off the incurable list."

The team later treated Nate's 5-year-old brother, Jacob, and is preparing to treat 9-month-old Sarah Rose Mooreland of Folsom, Calif. Hopes are high for them as well.

Nate suffers from recessive epidermolysis bullosa, which affects 1 in 100,000 children.

They lack a critical protein called collagen type VII that anchors the skin and lining of the gastrointestinal system to the body.

Their skin is extraordinarily fragile. Tearing and blistering occur with minimal friction, leading to painful wounds and scarring. Solid food produces erosion of the esophagus. Death usually results from malnutrition, infections or aggressive skin cancer.

The only treatment previously has been to wrap the skin in bandages.

The idea of using circulating stem cells to treat the condition was developed by Dr. Angela M. Christiano of Columbia University Medical Center. This is the first time that cells from bone marrow and cord blood have been used to treat a condition that does not involve blood.

Seven months after treatment,
Nate's body is making collagen type VII, Wagner said at a news conference Tuesday.

His face has plumped up and he has fewer blisters. "I have watched Nate improve every day," said his mother, Theresa.

The results will be published in a future issue of the New England Journal of Medicine.

thomas.maugh@latimes.com

---
http://www.latimes.com/features/health/la-sci-stem7-2008jun0

Mark said...

June 10, 2008

Red yeast rice extract XZK cuts risk of dying after heart attack
Nigel Hawkes, Health Editor

A form of fermented rice used as a herbal remedy and a colouring agent in food has shown remarkable results in patients who have suffered heart attacks.

Red yeast rice cut the risk of dying from a second heart attack by almost a third, and the risk of a non-fatal heart attack by almost two thirds, a trial in 5,000 people in China showed.

The results sound incredible but the trial was well-conducted and large, and the findings highly statistically significant.

They are less hard to believe when it is remembered that red yeast rice was the source of the first statin drug, lovastatin. So, in effect, the patients treated with red yeast rice were being given a statin in raw form.

Red yeast rice is made by fermenting rice with a yeast called Monascus purpureus. The result is a purple form of rice, known throughout the Far East under different names and sold in markets. It is also used to colour food.

In the trial, published online in the American Journal of Cardiology, 5,000 patients of both sexes who had already had a heart attack were divided into two groups and randomly allocated to be treated either with an extract of the red yeast rice, called XZK, or a placebo.

They were then followed for an average of four and a half years.

The research team, led by Dr Daniel Capuzzi of Thomas Jefferson University in Philadelphia, counted how many patients in each group suffered a serious second heart attack (including those who died from one). They found that the risk was reduced by almost half in the group given XZK.

There was also a dramatic drop in the number of cancer deaths, but the numbers were too small to draw any real conclusions — 29 cancer deaths in those on placebo, 13 in those on XZK.

Dr Capuzzi said that the health benefits from red yeast rice even exceeded those of statins, the acclaimed cholesterol-lowering drugs. “I think it is surprising that a natural [and unpatentable statin] product like XZK would have this great an effect” he said.

“If further testing and study prove true, my hope is that XZK becomes an important therapeutic agent to treat cardiovascular disorders and in the prevention of disease whether someone has had a heart attack or not.

“But it is important to recognise that we do not know exactly how Chinese red yeast rice works. The exact ingredients from the XZK capsules have not been isolated and studied yet. Still, the results were so profound, even outperforming statins prescribed in numerous Western populations, that further study should certainly be investigated.”

Red yeast rice has been used in China for thousands of years as a food preservative, colorant and seasoning and herbal medicine.

It is the ingredient that gives Peking duck its red colour.

Dr Capuzzi, who led the study together with Dr Zonliang Lu, from the Chinese Academy of Medical Science in Beijing, pointed out that the capsules used in the study were carefully prepared for the research and were not the same as red yeast rice supplements available in health food stores.

“Those over-the-counter supplements are not regulated, so exact amounts of active ingredient are unknown and their efficacy has not been studied yet,” he said.

---
http://www.timesonline.co.uk/tol/life_and_style/health/article4099336.ece

Mark said...

[This is a repost from:
http://www.pamrotella.com/health/copper.html]

Copper Deficiency: What aneurysms, white hair, and wrinkles have in common

Destroyed by Coffee, It is Claimed

[Posted 27 May 2004]

My father died of a brain aneurysm in 2001, a great loss for our family. Dad was one of the kindest people anyone knew -- a throwback to an earlier era, the type of man who'd stop to help strangers broken down at the side of the road. Of course I wanted to know what caused his aneurysm, and was quickly guided to Joel Wallach's work. Wallach was the famous veterinarian and research scientist who discovered cystic fibrosis in NASA test monkeys, finding that cystic fibrosis in both monkeys and humans was caused by a simple prenatal selenium deficiency rather than "genetics." Wallach later went on to treat deficiency diseases with vitamin and mineral supplements, particularly liquid colloidal supplements, and promoted supplementation in popular lectures and books.

According to Wallach, aneurysms are caused by a copper deficiency.

Copper deficiency can also cause white hair, wrinkles, and sagging in old age. Wallach recommends trying colloidal copper supplementation before opting for a face lift or any other type of lift, as the copper supplements usually work better. His most famous story about copper deficiency was the government turkey pellet disaster of 1957:

"Here's a good one. Dr S.C., 38 years old. Dead of a ruptured aneurysm. Even a turkey wouldn't die of a ruptured aneurysm! It's easy to prevent. We learned this in 1957. The government came out with its 'wonder food pellet' for turkeys. Guaranteed to grow them bigger, fatter, faster, and deader than a door nail. The farmers had to pick them up in bushel baskets, worst year ever for turkeys, they took them to the labs by the truck load, opened them up, and guess what they found? They all died of a ruptured aortic aneurysm, every last one, 50% of the entire nation's flock of turkeys... So they knew something was missing in the food. They analyzed the liver, blood, and muscles. Copper deficiency! Your arteries' elastic fibers need copper for tensile strength. The next year the copper content in the feed was doubled, and the mortality rate from ruptured aortic aneurysms dropped to 0%!"
- Joel Wallach from his "Dead Doctors Don't Lie" speech, as quoted on american-longevity.com and deaddoctors.com

According to Gary Null, another famous author/researcher and host of WBAI-New York's "Natural Living" show, coffee chelates the copper and calcium out of the blood.

This is of especial concern in a nation of coffee-drinkers.

Wallach recommends supplementation with colloidal copper, as with most minerals, to reverse some of the symptoms of copper deficiency. Some people try to obtain copper by wearing copper bracelets, a popular item with older people suffering from arthritis. Although some copper does pass though the skin, relieving some symptoms, Hulda Clark warns against the pure mineral version of copper, finding that it's often involved in cancer tumors. Wallach also cautions against the metallic form. Supplementation with copper is instead obtained through colloidal copper, or copper compounds more acceptable to the body.

My personal experience seems to support Wallach's findings. In the case of my father, dad's hair had been white since his 30s, and his skin started to wrinkle more than usual in his last few years. Dad was a heavy coffee drinker and he didn't believe in taking vitamin supplements, thinking instead that he could obtain needed vitamins and minerals through the food he ate. I also happen to be a heavy coffee drinker, and have a small amount of white hair already appearing.

However, when I take regular copper supplements, a lot of my hair grows back with its original color. Some of my friends have also tried copper supplementation, and notice a partial reversal of white hair within a few weeks. This makes me optimistic that problems associated with copper deficiency can be prevented, and sometimes reversed, by supplementation.

Wallach published three excellent books on vitamin/mineral deficiencies and their related diseases and disorders. They are Dead Doctors Don't Lie (he made a very famous audiotape lecture by the same name), Rare Earths, Forbidden Cures, and Let's Play Doctor!. These are excellent reference books. I hope readers will add them to their home libraries, and request that their local libraries carry them for public health information purposes.

---
http://www.pamrotella.com/health/copper.html

Mark said...

ESSIAC: CANCER CURE???
Why Hasn't This Cancer Cure Story Been Told?

For more than 50 years people from all over the world went to Ontario, Canada for cancer treatment with a simple herbal formula that gave miraculous results.

Why has this important news failed to reach millions of vitally interested people? The story of ESSIAC should be part and parcel of the natural healing lore of North America. Instead it is virtually unknown today despite the fact that it performed so well against thousands of cases of terminal cancer that it came within only three votes of being Legalized by the Canadian parliament. Still, chances are you have never heard of it.

Now, thanks to APW, you will not only know the whole story, you will know the secret ingredients of this herbal formula and how to get the herbs and make the tonic yourself.

What price truth? The medical monopoly and government proclaim to have spent billions in search of a cure for cancer. Except for the jobs created, the "War on Cancer" has been an utter flop. That great "war" began in 1970 with President Nixon's appointment of Benno C. Schmidt as "Cancer Czar" and about twenty years later some truly valuable information squeezed out when the cancer establishment finally admitted that the standard methods used (chemotherapy, radiation, surgery) have lost the war - they don't work. That may be valuable information - but it's not good news.

How valuable is information that testifies to genuine victories against cancer? There have been several widely proclaimed, but suppressed therapies that indeed saved lives and restored health - Dr. Koch, Dr. Ivy, Dr. Gerson, Hoxey et al. However, one of the greatest of these alternative cancer stories - the story of ESSIAC has not been openly told. Such information should not be withheld from the people, but until now, it has been! You have a right to know that a simple herbal remedy was credited for curing thousands, and for relieving the pain of more thousands of dying cancer patients.

"There is a tragic and shameful irony in the ESSIAC tale," notes a Canadian magazine, "In the beginning, a simple herbal recipe was freely shared by an Indian who understood that the blessings of the Creator belong to all."

You have probably heard such shameful stories before. How greedy individuals with power over the cancer establishment suppressed possible cures because they, the owners of that establishment, could not have absolute control. It happened in the case of Dr. William F. Koch, for example.

The ESSIAC story is one that has not been widely circulated. Even the various "alternative" circles in the United States know little if anything about this fantastic herbal remedy and the role it played for decades in Canada.

APW heard the story and read Dr. Gary Glum's book "Calling of An Angel." Then our investigative skills went to work. The well written and documented book actually raised more questions than it answered, and it did not reveal the formula. We learned that there are present day charges and counter-charges marring the whole truth, and people with vested interests are squabbling over rights to the formula which had been used so well by the late Rene Caisse. This fabled nurse used the formula unselfishly for decades. ESSIAC, in fact, is her name spelled backwards.

So many terminally ill patients became well again that public pressure forced the Canadian Parliament to react in 1939. The medical monopoly pulled out all stops, yet ESSIAC came within only three votes of becoming a legal therapy for cancer. The medical establishment won the war of politics and propaganda - but helped lose the war on cancer.

APW'S Tom Valentine probed the story behind the story, and found out the whole truth with the help of sincere people, doctors and laymen alike, who have no special axes to grind.

Dr. Charles Brusch of the famed Brusch Clinic in Cambridge, Massachusetts (physician to John F. Kennedy) - not only tested ESSIAC on human patients, but proved its value against his own cancer. He continues proclaiming it's great value today.

ESSIAC appears to be able to dissolve diabetes as well as cancer!

------------------------------------------------------------------

Excerpts from the book "Calling of An Angel" follows :

"I decided that if I should ever develop cancer," Rene wrote in her brief autobiography, I WAS CANADA'S CANCER NURSE, "that I would use this herbal tea." Then about a year later she was strolling with a wise and aged doctor when he stopped, took his cane and stroked a weed. "Nurse Caisse," he told Rene, "if people would use this weed there would be little or no cancer in the world."

The doctor told her the name of the plant Burdock, and Rene realized that it was one of the herbs the elderly woman had named as an ingredient in the medicine man's tea.

Rene Caisse was a practical and sensible woman, who was very busy with her nursing career, so she didn't get excited right away about the fantastic story of the herbal remedy, and even after the doctor's statement seemed to confirm that she might have something worthwhile, she didn't experiment or bother herself about the formula.

Then her mother's sister was diagnosed with cancer of the stomach and liver. The woman was given, at most, six months to live by her physician, R. O. Fisher, MD.

Rene knew the doctor well, so she told him the story of the herbal tea and asked permission to give it a try under his observation. Since there was apparently nothing else medical technology could do, Dr. Fisher consented on the spot.

“I obtained the necessary herbs, with some difficulty," Rene wrote, "and made the tea."

Rene put it succinctly in her book: "My aunt lived for 21 years after being given up by the medical profession. There was no recurrence of cancer."

One could write "needless to say" when describing the reaction by Dr. Fisher, but when it comes to cancer, the behavior of the medical profession is anything but predictable. However, Dr. Fisher was, indeed, impressed with what he observed. He asked Rene to treat other patients -- other "hopeless" cancer patients.

Dr. Fisher spread the word to other doctors and soon Rene was being asked to treat their "hopeless" patients as well. They, too, were impressed with the results. By this time the year was 1926. The rate of cancer death in the United States had risen to 103 per 100,000! Apparently, cancer was growing in the general population very much like a malignant tumor.

Obviously Rene became very attached to the herbal formula. She called it ESSIAC, which is Caisse spelled backwards.

Of all the factors inherent in the bureaucratic syndrome that sets itself up within the structures of large organizations, the NIH factor is among the most powerful of influences. Not invented here!

This is not the only reason for the infamous "waivers" required by large corporations, but it's likely the most sincere. Legally, the deep pockets of large corporations are a target for nuisance lawsuits, so they must take great care with what they accept or reject that comes to them from outsiders. None of this is truly germane to Rene's case, however.

The simplest fact is -- ESSIAC is not going to profit a large drug company, even if it is acknowledged as the "cure for cancer."

Firstly, it would wipe out most of the other product sales and secondly there is no way a company can monopolize a simple herbal tonic if the secret formula gets out.

They could protect the formula as Coca Cola has done, you might argue. True, but why ruin all that good business with the real thing? Cancer may be deadly, but loss of economy is even deadlier in many a person's view.

Rene really knew better than to try soliciting the large drug companies, but she tried anyway. Back when WWII broke out, she recalled the fact that ESSIAC had a way of stopping hemorrhages -- the face cancer case for example. She wrote to Parke Davis company in hopes they would use her formula to help wounded servicemen during the conflict. No dice! She wrote to Merck and to the Biochemical Institute at the University of Texas and received frustration for her efforts.

Finally, in 1973 at the age of 85 Rene Caisse tried Sloan-Kettering one more time. Perhaps she was stimulated by all the hype for President Richard Nixon's "War on Cancer," program where the rich within the cancer establishment were going to get richer.

The Laetrile controversy was in full bloom and Sloan-Kettering was in the middle. Many people today, including the man who served as the public relations officer for Sloan-Kettering, Dr. Ralph Moss, are convinced that the "tests" for any efficacy with Laetrile were rigged to fail.

Dr. Chester Stock, who figured prominently in the Laetrile squabble by the nature of his position, responded to Rene that if she would send ESSIAC, they would again test it.

Rene sent Sloan-Kettering one of the herbs -- probably the Burdock Root -- because it is the apparent tumor regressor. The other three are blood purifiers and symbiotic support substances. She also gave them careful instruction on how to prepare and inject the material.

Results of their tests were never released. Maybe future inspection of the archives at Sloan-Kettering may tell the truth about the results of the animal experiments.
------------------------------------------------------------------

The ESSIAC formula :

6 & 1/2 cups of Burdock Root (cut)
16 ounces of Sheep Sorrel herb (powder)
1 ounce of Turkey Rhubarb Root (powder)
4 ounces of Slippery Elm Bark (powder)

------------------------------------------------------------------

Preparation of ESSIAC herbal tea :

1) Measure out 8 ounces of the Essiac mix (the dry formula above)
2) Place two gallons of distilled water in a stainless steel kettle.
3) Bring the water to a brisk boiling point (about 30 minutes)
4) Put ESSIAC dry mix into the boiling water, stir and boil hard for about 10 minutes
5) Allow to sit and cool slowly for six hours.
6) After six hours, stir it thoroughly with a wooden or stainless tool
7) Let it sit for another six hours
8) Return kettle to stove and bring to a boil
9) When the boiling point is reached, turn off the heat and pour the contents through a stainless strainer into a second stainless kettle
10) Clean the first kettle thoroughly
11) Strain the contents a second time from pot two to pot one
12) Bottle the herbal tea immediately into dark amber bottles and seal it while still hot

(*** Dark amber bottles may be purchased from most any drug store or pharmacy ***)

13) Store in refrigerator


------------------------------------------------------------------

Directions for use of ESSIAC

Heat two ounces (four tablespoons) distilled water, then mix it with two ounces of ESSIAC tea taken directly from the refrigerator.

ESSIAC should be taken at bed time on an empty stomach, at least two hours after eating.

It can be taken in the morning on an empty stomach. If taken in the morning, do not eat for at least two hours after taking the ESSIAC.

Keep the ESSIAC refrigerated at all times.

Shake well each time before pouring.

---
http://web.archive.org/web/20050119093321/http://www.sumeria.net/health/essiac.html


(It seems that the institution of Sloan-Kettering or perhaps only individuals associated with it were involved in cover-ups about fluoride toxicity, human experiments on Americans who were given uranium to eat secretly, lying about lead in gasoline toxicity, lying about Essiac success, and lying about laetrile/B17 success.)

Mark said...

All Natural Cancer Therapy
Vitamin B17 Suggested Dosage



The information provided here is for educational purposes only.

It's not meant to diagnose, treat, cure or prevent any disease.

Always consult your physician. What is Cancer?... Click Here

-Cancer Is Not A Death Sentence-

Alternative Cancer Test... Simple, Easy and Safe.

In his brilliantly researched 1974 book World Without Cancer, researcher and author G. Edward Griffin explains the trophoblastic theory of cancer proposed by Professor John Beard of Edinburgh University, which states that certain pre-embryonic cells in pregnancy differ in no discernible way from highly-malignant cancer cells. Edward Griffin continues:

"The trophoblast in pregnancy indeed does exhibit all the classical characteristics of cancer. It spreads and multiplies rapidly as it eats its way into the uterus wall preparing a place where the embryo can attach itself for maternal protection and nourishment."

The trophoblast is formed in a chain reaction by another cell that Griffin simplifies down to the 'total life' cell, which has the total capacity to evolve into any organ or tissue, or a complete embryo. When the total life cell is triggered into producing trophoblast by contact with the hormone estrogen, present in both males and females, one of two different things happens. In the case of pregnancy the result is conventional development of a placenta and umbilical cord. If the trophoblast is triggered as part of a healing process however, the result is cancer or, as Edward Griffin cautions: "To be more accurate, we should say it is cancer if the healing process is not terminated upon completion of its task."

Stunning proof of this claim is readily available. All trophoblast cells produce a unique hormone called the chorionic gonadotrophic ( CGH ) which is easily detected in urine. Thus if a person is either pregnant or has cancer, a simple CGH pregnancy test should confirm either or both. It does, with an accuracy of better than 92% in all cases. If the urine sample shows positive it means either normal pregnancy or abnormal malignant cancer. Griffin notes: "If the patient is a woman, she either is pregnant or has cancer. If he is a man, cancer can be the only cause." So why all of the expensive, dangerous biopsies carried to 'detect' cancerous growths? One can only assume that medicare pays doctors a larger fee for biopsies than pregnancy tests.

Many physicians are convinced that any cutting into a malignant tumor, even for a biopsy, increases the likelihood that the tumor will spread. If you are about to have surgery, or even a biopsy, where the cancer cells are going to be disturbed, it is imperative that you take vitamin B17 to kill the remaining free cells. Vitamin B17 can only help and will definitely not hurt.

If you do NOT have Cancer

As a preventative Dr. Krebs asserts that 7 to 10 apricot seeds per day will make it nearly impossible to develop cancer in one's lifetime. For optimum effect, the apricot seeds should be chewed raw and pulped in the mouth before swallowing. They should NOT be swallowed whole. One or two vitamin B17 tablets ( 100 mg ) is an acceptable supplemental dosage per day. Also, if you eat three apples a day, seeds and all, the seeds in the three apples are sufficient vitamin B17, that's about 90 apples per month. The apricot seeds should be taken throughout the day ( not all at once ), with at least one hour in between each serving. A good rule-of-thumb: "Don't eat more seeds at one time than you likely would consume if you were eating the whole fruit."

If you are really serious about your health... We suggest: Apricot seeds ( whole food is best ) or vitamin B17 ( 100 mg ) along with digestive enzymes with at least 3 mg Chymotrypsin, if these proteolytic enzymes are to be used as a digestive aid the recommended dosage is 1 or 2 tablets just prior to a meal. The proteolytic enzymes should also be taken on an empty stomach or 2 hours after meals, for the benefits are many. They should NOT be chewed or crushed, because of stomach acid. Drink plenty of room temperature high pH spring or mineral water. Finally, to maintain health, the diet should consist of 60% alkaline forming foods and 40% acid forming foods. A list of Acid / Alkaline Forming Foods... Click Here Purpose of Enzymes... Click Here

Balancing the pH is a major step toward well-being and greater health. The body has to have a balanced pH like most living things on earth or it does not function correctly. The alkaline level is very important because research has already proven that disease cannot survive in an alkaline state and yet they thrive in an acidic environment. Understanding pH Level... Click Here

“My people are destroyed for lack of knowledge: Hosea 4:6”

Doctors and Clinics doc2.gif (112 bytes) Find a Doctor

Vitamin B17 may help prevent cancer, but if one already has cancer, a complete protocol is required including diet, enzymes, exercise, detoxification, and supplementation, as prescribed by a physician. It is best to work with an alternative physician to be sure you are using the best approach to treat your particular condition. These doctors and clinics are offering Laetrile / B17 as part of their therapy. Get your doctor to work with you — not on you.

Body Detoxification *Chapter IV* One Answer to Cancer

CAUTION: In reality, a person very rarely dies of cancer. It is always starvation and toxicity. As the malignant tumor grows it gives off waste products, which must be eliminated through the colon, liver, kidneys, lungs and skin. These waste products accumulate and gradually overburden the body. Most persons then die of toxemia. Before any disease can be cured, the waste products and impurities must be cleansed from the body. The sooner this is done, the sooner the body can begin repairing itself.

The "detoxer" must be prepared to accept that there will be a "healing crisis." While on a cleanse the body will purge. The release of toxins will bring up physical and emotional trauma that will be reflected in certain symptoms. A healing crisis can last a few days and produce these symptoms: fever, headaches and other aches, fatigue, skin eruptions, emotional irritability, gas, temporary constipation or diarrhea, temporary loss of menstruation, yawning, and muscular tension. In most cases, it is important not to use drugs to suppress these symptoms, but instead, to encourage the release of toxins from the body. These symptoms are an expression of release and must come out.

Small Intestine Cleanse... Click Here | Liver / Gallbladder Cleanse... Click Here

Dr. Kelley recommends that you begin the detoxification process even before you have the nutritional supplements in your possession. It is absolutely imperative that the patient carefully follows the detoxification process after the supplements begin stimulating the release of wastes and debris. Go to and read... * Chapter IV * Body Detoxification by Dr. William Kelley

IF YOU HAVE CANCER

"If you have Cancer, the most important single consideration is to get the maximum amount of Vitamin B17 into your body in the shortest period of time. This is secondary to the medical skill involved in administering it, which is relatively minimal." - Ernest T. Krebs, Jr.

Vitamin B17 ( laetrile - amygdalin ) 500 mg: Two ( 2 ) of these tablets, three ( 3 ) times daily. This is non-toxic, however you may get very nauseous and have gastric upset if you start out with the full amount. The tablet size is 500 mg. If you have difficulty in swallowing, the tablets may be broken up and added to soft food. You have to decide weather to have an empty stomach or not. After the initial 60 days of this amount of vitamin B17 a maintenance dose of 3 tablets per day for the following six months to a year is recommended according to the severity of the cancer. If the cancer had metastasised, take three tablets a day for life. It is in Dr. Krebs opinion ( the vitamin B17 discoverer ) to take three tablets daily for life even if the cancer hadn't spread.

For prevention of cancer and the maintenance of remission there is nothing as effective as laetrile or vitamin B17. Its non-toxicity permits its use indefinitely in the prevention of relapses and the prevention of metastases. Surgery, Radiation and Chemotherapy can only be administered for a limited time, afterwards patients are left without any protection.

For the apricot seeds and/or tablets ( start out with a low dosage and build up ). It is okay if you cannot handle the full dosages that we speak of - use Ginger tea to stop upsets. Some patients ( according to the severity ) take up to eighteen 500 mg tablets per day for the first month.

Go to and read... The Ultimate Guide to Vitamin B-17 Metabolic Therapy... Click Here
The Story of Vitamin B17... Frequently Asked Questions ( From Worldwithoutcancer.org.uk )

Importance of Zinc: Zinc is the transportation mechanism for laetrile and nitrilosides in the body. Biochemists and researchers have found that you can give Laetrile to a patient until its coming out of the ears of the patient, but, if that patient did not have sufficient level of Zinc, none of the laetrile would get into the tissues of the body. They also found that nothing heals within the body without sufficient Vitamin C. They also found that magnesium, selenium, vitamin A, and B all played an important part in maintaining the body's defence mechanism. This is why its very important to understand that cancer is best treated with a total nutritional program consisting of diet, vitamins, minerals, laetrile, and pancreatic enzymes.

The RDA for zinc is 15 mg per day. If you're already taking a multimineral supplement, you're probably already getting adequate zinc and copper. Do not take more than 50 milligrams per day and do not supplement zinc without supplementing copper ( ratio of 8 : 1 ).

In general, high-protein ( Acid Forming Foods ) are good sources of zinc. Fruits and vegetables ( Alkaline Forming Foods ) are not generally good sources of zinc. Best Source Foods for Zinc

Vitamin B17 Along With:
Apricot Seeds, Digestive Enzymes, Okra-Pepsin-E3, and Coral Calcium.

Apricot Seeds ( also called Kernels or Pits )

Many people take Laetrile / B17 in its natural state: bitter almonds or apricot seeds. And many of these people end up in the emergency wards nearly poisoned to death. This is because they are not following the directions, or taking the seeds without any supervision. The apricot seeds contain cyanide. Although Laetrile / B17 is less toxic than sugar and 21 times less toxic than aspirin, you can take too much... Unfortunately, you can take too much of anything, even water. So to question the use of vitamin B17 on the grounds of toxicity is extraordinary as all the drugs used currently in orthodox cancer therapy are extremely toxic. Now, here is the irony of all of this. Milligram for milligram, the chemotherapeutic agents which are commonly used in the treatment of cancer today, are hundreds of times more toxic than laetrile. Nuff said...

Here is how it works: Cancer loves sugar. The sugar in the apricot seeds surrounds cyanide. The cancer draws in the sugar, eats it, and releases the cyanide at the cancer cell and only at the cancer cell; sort of like a smart bomb. The cancerous cells are destroyed, but normal cells are not affected. This whole process is known as selective toxicity. Only the cancer cells are specifically targeted and destroyed. The problem with this is that some people take too much. While others take enough, but also have a diet high in sugar. Simply put: you must stop all sugar consumption, cut back drastically on carbohydrates, and then take your apricot seeds. Otherwise, you can do your body a great disservice, and not do anything to battle your cancer.

Suggested Dosage:
Apricot seeds and other nitrilosides such as wheat grass and millet. Apricot seeds should be ground up in everything you eat. Anywhere up to 70 seeds per day. The FDA recommend not to ingest more than 6 seeds per hour because toxic reactions may occur, such as gastric upset, headache, vomiting and loose bowels. Many people take 15 seeds per day. Can skip a day and then take 40 the next day, and so on and so on. Bone cancer survivors take 5 seeds per waking hour with pancreatic enzymes, etc... ( I'm sure not e v e r y hour ). In general, eat one apricot seed for every 5 pound of body weight, daily. Example: 180 lbs. = 36 apricot seeds daily.

Dr. Krebs recommends 30 to 35 seeds per day as nutritional support for clinical cancer sufferers. To start, it is recommended that along with the purified forms of B-17, either intravenous or oral, cancer patients eat one apricot seed for every 10 lb. of body weight, at least one hour in between each serving. If this dosage is tolerated well, it may be increased to 30 to 35 kernels per day.

If you are using the 500 mg tablets of vitamin B17, the effect is magnified if you eat 5 - 7 apricot seeds with it because the other vitamins, minerals, and enzymes in the seeds complement the vitamin, thereby will help the actual vitamin B17 tablet assimilate into the body. If both laetrile and kernels are taken, then Dr. Krebs recommends that there should be two hours between taking them. While high doses of laetrile are taken, the number of kernels taken can be less.

Shred these seeds and sprinkle them on hot vegetables, baked potatoes, soup, salads, cereals, and trail mix. Others, who do not mind the bitter taste of the seeds, prefer to eat them on their own. For optimum effect, the apricot seeds should be chewed raw and pulped in the mouth before swallowing. They should NOT be swallowed whole. Foods containing B17... Click Here Note: Potatoes are high in carbohydrates which turns into glucose ( sugar ), use sparingly.

“And God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, and every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat. Genesis 1:29”

Digestive Enzymes Fluoride is a destroyer of enzymes... Click Here

Several researchers including Dr. John Beard, Dr. Ernst Krebs, Jr., and Dr. Dean Burk found that the cancer cell is coated with a protein lining and that it is this protein lining ( or covering ) that prevents the body’s normal defenses from getting to the cancer cell. They found that, if you can dissolve the protein lining from around the cancer cell, the body’s normal defenses, the leukocytes ( white blood cells ), will destroy the cancer cell.

The body uses pancreatin, a secretion from the pancreas to dissolve the cancer cells. As we age, the pancreas is less and less able to make this important substance. By taking pancreatin orally, it is possible to increase the levels of its active ingredients in the blood, thereby helping the body break down the cancer cells and remove them from circulation. Pancreatin as a digestive enzyme is available from any health food store in the country, however this type of pancreatin is useless for the cancer patient. The active ingredients in pancreatin which have shown to have tumor dissolving abilities are trypsin and chymotrypsin.

Here is how it works: Proteolytic ( protein-digesting enzymes ), produced by the pancreas, thus also called pancreatic enzymes. The pancreatic enzymes will be the front line defense against cancer with the vitamin B17 as your back-up. These two enzymes, trypsin and chymotrypsin, are essential to the body's fight against cancer. They are the cancer patients best friend, they eat away and dissolve the protein coating of the cancer cell making it easier for the vitamin B17 and your natural white ( killer ) blood cells to completely destroy the cancer cells.

Suggested Dosage: 3 to 6 tablets with at least 20 mg Chymotrypsin each tablet, three or four times daily on an empty stomach or 2 hours after meals. They should NOT be chewed or crushed, because of stomach acid. If you have difficulty in swallowing, try adding the tablets to soft food, soup, etc. and swallow whole. Use little food as possible. You need the pancreatic enzymes to digest the protein coating around the cancer cell, not to digest your food. When all the enzymes are used up digesting food, there are none left to destroy cancer cells.

For systemic use the dosages vary depending on the severity of the condition, but the proteolytic enzyme tablets should be used as far from meals as possible... One or two tablets can also be taken with meals to aid digestion and reduce toxic undigested food. Again, very important, be sure the pancreatic enzymes that you buy each tablet have at least 20 mg Chymotrypsin, more is better. If you take a lower-strength formulation, you will need a higher dosage.

Also, fresh pineapple and papaya are good sources of enzymes that aids in digestion by breaking down protein. It's a very common practice to consume half a pineapple a day when taking B-17 therapy. Enzyme bromelain obtained from pineapples and enzyme papain obtained from papaya. Go to and read... Cancer Treatment with Enzyme Therapy... Click Here

[ People with allergies to beef, pork, pineapples, and papaya may suffer allergic reactions to enzyme supplements. Tablets are often coated to prevent them from breaking down in the stomach, and shouldn't be chewed or crushed.]

Okra-Pepsin-E3 ( Cleansing The Small Intestine )

It digests the mucus that coats the walls of many people’s small intestine. Certain foods, such as pasteurized milk and many cooked foods, cause the mucus buildup on the wall of the small intestine ( raw foods do not cause this mucus buildup ). A person with a severe mucus buildup could take $1,000.00 worth of supplements a month along with a good diet and still get almost no nutritional value from them.

If capsules are taken for a few days to several weeks, one after each meal ( reduce the amount of capsules if diarrhea occurs ), the mucus will gradually be digested. The blood can then receive more nutrients from the food, even if it is from a poor diet. Then, once a year, take the Okra-Pepsin-E3 capsules again for a few days or a week to keep the mucus from building back up.

The Okra is a very sticky, gooey, vegetable material. It tends to stick the Pepsin enzyme to the mucus on the intestinal wall long enough to digest some of the mucus. The E-3 is a powerful tissue repair factor. It was originally developed for the patient with stomach ulcers or colitis.

Coral Calcium ( 1100 mg capsules 90 ct. bottle )

Dr. Otto Warburg established long ago in his Nobel prize winning studies that cancer cannot grow in an alkaline environment because there is too much oxygen. Acidity drives oxygen out providing an environment in which cancer can grow. The best way to raise body pH is making sure that adequate minerals, particularly calcium are present. In general, green vegetables are high in calcium. Kale, broccoli, and collard greens are good sources of calcium, buy a juicer and start juicing. Non-dairy Calcium Foods... Click Here

As the bio-available calcium and other alkalizing minerals get into the blood and cells the body pH begins to return to the normal slightly alkaline level. Most disease thrives in an acidic environment. Maintaining a healthy blood pH ( 7.35 - 7.45 ) may help in the recovery from a degenerative disease and equality important, sickness and disease has difficulty ever getting started in an alkaline terrain. At a pH slightly above 7.4 cancer cells become dormant and at pH 8.5 cancer cells will die while healthy cells will live.

Suggested Dosage: 2 capsules 4 times daily... Your body absorbs calcium less efficiently as your intake increases, therefore it is best to take calcium in small doses throughout the day. It is much easier for your body to absorb the calcium ( actual calcium content ), if no more than 500 mg is taken at one time. This is why it is recommended to drink quality water with ionic coral calcium throughout the day, as opposed to all at once.

“For the life of the flesh is in the blood: Leviticus 17:11”

Conclusion... The Bottom Line

There are two factors that are ALWAYS present with cancer no matter what else may be present. Those two factors are Acid pH and Lack of Oxygen. Those two factors always have to be present for cancer to develop and make tumor cells thrive. The body must be restored to a normal, slightly alkaline pH and one must eat the apricot seeds along with digestive / pancreatic enzymes with at least 20 mg Chymotrypsin, more is better. All else is additional, but important. It is best to work with an alternative physician to be sure you are using the best approach to treat your particular condition. Doctors and Clinics that offer B17 as part of their therapy... Click Here

We suggest for existing cancer the following:

Existing Combo Package: 30 Day Supply... Stay on this dosage for 60 days.

* Two pound of Apricot Seeds - 40 to 45 seeds daily. Build up to this dosage slowly.
* ( 2 bottles ) Vitamin B17 500 mg ( 100 tablets ) - 2 tablets 3 times daily.
* ( 2 bottles ) Omnizyme Forte ( 200 tablets ) - 4 tablets 3 times daily, on empty stomach.
* Okra-Pepsin-E3 ( 150 capsules ) - 2 capsules, after each meal.
* ( 3 bottles ) Coral Calcium ( 1100 mg capsules 90 ct. bottle ) - 2 capsules 4 times daily.
* This helps detox the body of cancer waste products; impurities and helps raise body pH. Drink ½ gal. of high pH spring or mineral water daily. Your best choice is a combination of water and fresh vegetable juices, one quart of each daily. ( Buy a juicer and start juicing.)

[ If you have congestive heart failure or kidney disease, or if you are taking diuretics, talk to your doctor before increasing your water and/or juice intake.]

CAUTION: One must carefully follow the detoxification process after the supplements begin stimulating the release of wastes and debris. Start out with a low dosage and build up. If you take too much too quickly, the waste products and poisons must exit the body and may overload your elimination system and this can be serious. Allow your organs time to remove this debris from your body. Build up your dosage slowly and your body will thank you for it.

How to Order... Click Here

Maintenance Dose... After the initial 60 days

Maintenance Dose Combo: One Month Supply... For 6 months to a year.

* One pound of Apricot Seeds - 20 to 25 seeds daily.
* Vitamin B17 500 mg ( 100 tablets ) - 1 tablet 3 times daily.
* Omnizyme Forte ( 200 tablets ) - 2 tablets 3 times daily, on empty stomach.
* Coral Calcium ( 1100 mg capsules 90 ct. bottle ) - 1 capsule 3 times daily, after meal.
* Drink ½ gal. of high pH spring or mineral water daily. Your best choice is a combination of water and fresh vegetable juice, one quart of each daily. ( Buy a juicer and start juicing.)

How to Order... Click Here

Here Is A More Powerful Anti-Cancer Protocol For Terminal Malignancystars5.gif (394 bytes)Click Herestars5.gif (394 bytes)

This is an ideal therapy for anyone with terminal malignancy. If you know someone who has been told get your affairs in order you only have 3 to 6 months to live that person will have a reasonable chance of recovery if they add cesium and other key nutrients to the above supplements. They may need to take 6 grams of cesium daily to recover. Other cancer patients who have not lost their appetites and are eating normally can also benefit from this powerful protocol, just leave out the cesium part or give cesium a try with the minimum dosage of 1 gram three times daily with observation for signs of recovery ( receding tumor masses ). It is important to be sure to balance the intake of cesium and potassium... This protocol should be effective for all forms of cancer. Fruits, vegetables, supplementation, and detoxification are key. To get started... Click Here

Note: Daily doses of cesium accumulate in the body. The toxic dose for CsCl is 135 g.

How To Prevent The Spread of Cancer

One mechanism that cancer cells use to expand in the body is through digesting their surroundings. This mechanism was described by Dr. Matthius Rath in his book on cancer. Cancer cells produce and secrete millions of enzyme molecules, which, like scissors, cut collagen and tissue that surrounds cells. Cancer cells use these enzymes to cut little holes in the blood vessel wall and get into the blood stream where they can travel to other organs, such as the lungs. Using the same mechanism, cancer cells can settle there and start new tumor growth. This stage, called metastasis, is the most dangerous stage of cancer. If a tumor stays in one place it rarely endangers our life. But about 90% of cancer deaths are the result of metastases, when a tumor invades various organs in the body.

It must be natural mechanisms that keep cells in place and prevent the spread of cancer. Dr. Rath suggested that our bodies can use lysine, a natural amino acid, to block the action of collagen digesting enzymes. Research has shown that a combination of vitamin C with the natural amino-acids lysine, proline, and specific extracts from green tea can block the invasion of cancer cells. Lysine, like vitamin C, cannot be produced in our body. We can only get it from our diet, therefore, deficiency of lysine is likely. This means that our body's ability to control collagen digestion can be compromised if intake of lysine is too low. Food sources of lysine are numerous, but the richest sources include cheese, eggs, fish, lima beans, milk, potatoes, pork, poultry, red meat, soy products, yeast, all protein-rich foods. Vegetables are generally a poor source of lysine, with the exception of beans, peas, and lentils. Source Foods for Vitamin C

Dr. Rath uses the nutrient combination of vitamin C, the amino-acids L-lysine and L-proline, and Epigallocatechin Gallate ( EGCG - a polyphenol extract from green tea ) and has found these to be very effective in the treatment of a wide variety of human cancers, including those of the skin, liver, breast, prostate, colon, lung, and brain. There is no reason why they should not also be effective in the treatment of Soft Tissue Sarcoma. More good news... These same nutrients and same doses ( see below ) work well with cardiovascular disease, by clearing arteries of plaque. This nutrient combination will help in preventing and reversing both cancer and heart disease. As a preventive measure against cancer, heart attack and stroke cut dosage ( below ) by 70% or 50% for those with family history of cancer, heart attack or stroke which are considered high risk.

We believe that the daily doses used by Dr. Rath and his team in the treatment of cancer are in the region of 6g ( 6000 mg ) of vitamin C, 6g ( 6000 mg ) of L-lysine, 3g ( 3000 mg ) of L-proline and 1g ( 1000 mg ) of EGCG. A high-dose multivitamin and mineral supplement would also be a good idea. Product choice is "Epican Forte" by Dr. Rath. To find a store that carries Dr. Rath's products... Click Here — Go to and read... Cancer Can Be Beaten by Matthius Rath, M.D. Also see, Heart Formula - Dr. Rath's anti-cancer protocol (minus green tea)... Click Here. With Heart Technology Formula there are No Pills! Just mix in 8 ounces of water or juice. You need to order Green Tea to take with Heart Technology Formula... Click Here or do internet search.

Note: The beneficial effects is reportedly much more pronounced and immediate when sugar and refined carbohydrates is eliminated. Sugar feeds cancer and sugar can crowd out vitamin C.

The Tumor Doesn't Disappear

How is success against cancer measured? Is it the length of life? The quality of life? The feeling of well-being and absence of pain? The ability to function normally on a daily basis? All of these are the criteria used by doctors who apply nutritional therapy. They are not concerned with the size of a tumor because they know most tumors are a mixture of malignant and benign cells. Orthodox medicine, on the other hand, is totally focussed on the tumor ( in cancers where tumors are formed ). A living and healthy patient with a tumor reduced by only 15% but stable would be classified as a failure, whereas a sick and dying patient with a tumor reduced 60% would be a success.

Hundreds of people make the wrong decisions because they were expecting their tumor to disappear. The tumor doesn't disappear. When the tumor shrinks down that's it, start rejoicing and continue on your natural regimen. Most doctors will still see a tumor and continue to give a person chemotherapy ( until they're dead ) in attempts to make the tumor disappear. Malignant ( cancerous ) tumors are only a small percent cancer and when the cancer part starts dying off, the tumor only shrinks down the percent that the tumor was cancerous.

In other words, if a kidney tumor is 10 percent cancerous the tumor will shrink down only 10 percent. So, if you get a CAT scan, which one should never get ( with 6 CAT scans there is over 60% more of a chance of one developing Leukemia; MRI's are much safer as they use magnetic imaging and not radiation ) a 10 percent shrinkage can be concluded as "NO CHANGE".

In general, if the tumor is easily accessible and if the patient wishes to do so, have the tumor removed. By removing the tumor the body has one less thing with which to cope. If the tumor is remote, not causing any problem and the patient agrees, leave the tumor alone. The tumor is merely a symptom, not a cause. If you take care of the body, the body will take care of the tumor. That doesn't mean that the tumor will go away, but it is unlikely to cause a problem.

Do NOT stop eating the apricot seeds along with digestive / pancreatic enzymes and one must maintain the body at a normal, slightly alkaline pH - 7.35 to 7.45. The ideal pH for blood is 7.4

Combined Medical Treatment

There are no contraindications to the use of Vitamin B17 nor any of these products along with surgery, radiation, and chemotherapy. Surgery, for example, is often life saving in cancer by correcting blockages, repairing fistulas, arresting haemorrhages, and removing cancerous growths that are impinging upon vital organs.

A patient on chemo, experiences significantly less side effects from chemotherapy, if patient simultaneously uses the therapies mentioned. Example: Enzymes reduce the side effects of chemo by eliminating the dead cells and the chemicals from the body. Also you would recover faster from chemo. When the body is getting rid of chemicals from chemo you would sweat a lot.

Several studies conducted by European scientists show that oral pancreatic enzymes taken with chemotherapy and radiation improves the response rate and reduces the side effects significantly.

Alkalinity Nutritional Program

Fruits, vegetables, and supplementation are key. Eating the normal western diet is a recipe for disaster for the cancer patient. Poor nutrition provides a favorable environment for cancer to grow and develop. Proper nutrition supports the immune system, starves cancer cells, and helps maintain the body at a normal, slightly alkaline pH - 7.35 to 7.45. Disease cannot survive in an oxygen rich alkaline state. The only place in your body where there is no oxygen is the cancer site. The best way to raise body pH is making sure that adequate minerals, particularly calcium are present. In general, green vegetables are high in calcium. One of the quickest ways to raise your body pH is to take in green vegetable juices. Kale, broccoli, and collard greens are good sources of calcium, buy a juicer and start juicing. The juicer is the most important appliance in the kitchen for the cancer patient. To battle cancer with fasting the best choice is a combination of water fasting and juice fasting using 2 - 5 glasses of juice per day. Non-dairy Calcium Foods More Information on Fighting Cancer With Juice Fasting... Click Here

So if we are going to purchase a juicer, should we buy a centrifugal or a mastication-type juicer? At the Gerson Clinic in Mexico, they are healing the "incurables" ( lung cancer, lupus, spreading melanoma, lymphoma, brain cancer, breast cancer, multiple sclerosis, migraines, etc.) through the use of freshly-extracted raw vegetable juices. These people at the Gerson Clinic are the most knowledgeable people we know to ask what kind of juicer works best. So what do they teach? They teach that only mastication-type juicers will do the job because centrifugal juicers leave most of the nutrients in the pulp, which then gets thrown away. ( The laboratory report where they ran five pounds of carrots through a centrifugal juicer and a mastication-type juicer, and the mastication-type juicer removed three to four times more nutrients than the centrifugal ). The mastication-type juicer leaves very few nutrients in the pulp. For this reason, we recommend only mastication juicers for the cancer patient.

The Cancer Killer
1 beet - 1 carrot - 1 celery stick - ½ potato - 1 radish

Rudolf Breuss's, anticancer mixture has helped thousands of suffering people. This juice blend, during fasting, exerts a death blow on cancer. This was attested by over 24,000 patients who wrote him describing relief from their diseases. His patients were given small amounts of this juice over 42 days. A tea composed of nettle, St. John's wart, marigold, artemisi, and monarda was also given. By "starving out" the cancer, Rudolf Breuss reported a 96% success rate for the thousands of patients he treated over 30 years of practice. Rudolf Breuss died in 1989 at 93 years of age. Composition: 55% beet root, 20% celery root, 20% carrot, 3% potato, 2% radish.

The cancer patient will want to give up cooked and commercially produced meat such as beef, pork, lamb and fowl immediately ( except for raw liver ). Cooked meat is harmful for the cancer patient, as the very same enzymes used in its digestion ( Trypsin and Chymotrypsin ) are needed for fighting and digesting the cancer. When all the bodies reserves of these two enzymes are used up, there are none left in the blood to destroy cancer cells. All natural, self-made enzymes your body can produce should be used to fight the cancer. Plus, animal protein is Acid Forming. Go to and read... * Chapter V * Metabolic Cancer Cure Diet by Dr. William Kelley

Sugar Feeds Cancer... You want to take away the single fuel on which cancer thrives, SUGAR! Glucose ( sugar ) is the only form of fuel that cancer can utilize. Also, Sugar is Extremely Acid Forming - pH 5.0 to 5.5. Cancer loves cooked foods and cancer loves sugar. When one has cancer and eats something loaded with sugar it's just like throwing a cup of gasoline on a smoldering fire. Very simply put: You must stop all sugar consumption and one must cut back drastically on carbohydrates. If you hate your cancer, then starve it. The quest is not to eliminate carbohydrates from the diet, but rather to control blood sugar within a narrow range to help starve the cancer. Try to keep total carbohydrate count to under 75 grams per day, under 50 is ideal. These tools may help... Carbohydrate Count | Carbohydrate Calculator

Carbohydrates are fiber or non-fiber. Fiber carbs are good for you, non-fiber carbs are bad for you. Carbs turn into glucose ( sugar ) in your blood and this sugar feeds cancer. Some foods high in carbohydrates are breads, cereals, grains, pasta, starchy vegetables ( peas, corn, dried beans, potatoes ), milk, yogurt and fruit. Balance your intake of these foods and eat these foods in moderation... Cancer patients need to eat more Fibrous carbs like cucumber, greens, tomato, broccoli, cauliflower, onions, snow peas, peppers, cabbage, asparagus, etc., these are great. Also, dry beans of all types are a good source of food for the cancer patient, and may be used two or three times a week at anytime of the day. Carb count - ½ cup cooked about 20 grams.

The Very Best Foods
( Juiced, raw or steamed vegetables would provide the best nutrient value.)

Vegetables: Avocado, beets, broccoli, brussel sprouts, cabbage, carrots, cauliflower, celery, chicory, chives, collard greens, cucumbers, dandelion, endive, fennel, garlic, kale, leeks, lettuce, sea lettuce, mustard greens, nettles, okra, onions, parsley, parsnips, radishes, spinach, squash, tomatoes, turnips, and watercress.

Fruits: Apples, apricots, avocado, bananas, berries, cantaloupe, cherries, cranberries, currants, dates, figs, grapefruit, grapes (seeded), lemons, limes, mangos, melons, nectarines, olives, oranges, papayas, peaches, pears, persimmons, pineapples, plums, pomegranate, and quinces.

Seeds and Nuts: Almonds, beechnuts, black walnuts, butternuts, coconuts, english walnuts, filberts, pecans, pignolias (pine nuts), and pumpkin seeds.

It is BEST to take nothing into the body that has been cooked or processed: Avoid sugar, beer, sodas, ice cream, fried foods, table salt ( sea salt - okay ). The diet should focus on fruit ( fresh pineapples ), vegetables and high pH spring or mineral water. Drink plenty of room temperature spring or mineral water. To be safe, we recommend less fruit, more vegetables, and no refined sugars in the diet of cancer patients. To restore health, the diet should consist of 80% alkaline forming foods and 20% acid forming foods. A list of Acid / Alkaline Forming Foods... Click Here

Summary: The greener the vegetable the better.

“A little wine should be used, as the Bible says: l Timothy 5:23”
( High quality red wine, no more than 4 oz. daily to build blood.)

Eat nuts, berries, seeds and every kind of herb you can get your hands on. Eat Ezekiel 4:9 bread. This bread can be found in the health food store under the name "Ezekiel 4.9 Bread". In Ezekiel 4:9, God gives the perfect recipe for making bread. B17 is found in small degrees in this bread. The Bible says that bread will make the heart strong. Foods containing B17... Click Here

Increase Intake of Omega-3 Fatty Acids in Fish Oil to Fight Against Disease. Reduce the amount of omega-6 fats and increase the amount of omega-3 fats. To do this you will need to avoid vegetable seed oils such as corn, cottonseed, sesame, safflower, sunflower, and partially hydrogenated soybean oil. Omega-3 fatty acids slow the growth rate of tumors significantly, or even decrease their size. Most people find that Carlson's Cod Liver Oil smells fresh and does not have a bad taste. They have a lemon-flavored product that tastes like lemon melted butter. More super foods... The following foods have the ability to help stave off cancer and some can even help inhibit cancer cell growth or reduce tumor size. Cancer Fighting Foods and Spices... Click Here

What Omega-3 Can Do For You: Lower triglycerides and raise HDL in the blood. Lower low density cholesterol in the blood. Greatly reduce risk of heart disease. Aid in regulation of blood sugar levels. Reduce rate of inflammatory diseases like arthritis, lupus, migraine headaches. Reduces platelet "stickiness" and therefore reduces the tendency towards atherosclerosis - the clogging up of the arteries with cholesterol plaque. Inhibits tumor growth and lowers cancer risk.

Most people recommend Carlson's Cod Liver Oil or Dale Alexander Fish Oils by Twinlab, they are found at many health food stores. With Cod Liver Oil you also get vitamin A and vitamin D. Note: Since Omega-3 fatty acids thins the blood, those taking blood thinners such as coumadin should only use fish oil under the supervision of a physician.

WARNING: IF YOU ARE DRINKING DIET SODAS WHICH CONTAIN ASPARTAME OR USING SUGAR-FREE PRODUCTS - READ THIS!! Diet sodas, foods labeled as "sugarless" "sugar free" "diet foods" "low calorie" and the like - You had better be careful and read the label to see if they contain ASPARTAME. Please check labels carefully Aspartame is poison and extremely acid forming. Take the 60 day aspartame test. Give up all aspartame for 60 days and note the improvements in your health. Check it out... Do internet search on "aspartame and/or diet cola". [ note in Australia ( and UK ) who just have numbers on things - not names - Aspartame is 951 ]

“Worship the Lord your God, and His blessing will be upon your food. Exodus 23:25”

Other Potent Cancer Fighting Products
We recommend adding these Cancer Fighters to your therapy.

Cansema ( 8 fl. oz. ) Liquid Tonic - ( The paste is best for skin cancer )
Only two teaspoons per day, on a full stomach. The Cansema paste actually pulls tumours out of the body. The liquid tonic is much more bearable than having a tumour ulcerate from the body while using the salve. Cancema kills the parasites ( bugs in the blood ) which damage cells turning them cancerous. It is a base or alkaline which takes away the acidity of the body, it is a very powerful treatment for cancer. This product is not, as a general rule, intended for long-term use. You want to use the product to specifically treat your problem and then discontinue use. We do NOT sell this product. To order Cansema... Click Here or do internet search.

Oxygen Elements Plus - ( formerly known as Hydroxygen Plus )
A powerful free radical scavenger that helps your cells "breathe" better, while rapidly, deeply detoxifying. Just add drops to eight ounces of water or juice and take with or after meals. For a therapeutic dosage, increase slowly to 21 drops three times a day and maintain this amount for one to two months before dropping to the maintenance amount of 7 drops three times a day. We do NOT sell this product. To order this supplement... Click Here or do internet search.

Cancer vs. Health... One Final Thought

It is very important to understand that cancer is BEST treated with a total nutritional program consisting of diet, vitamins, minerals, laetrile, pancreatic enzymes, exercise, detoxification, and supplementation. Some of these supplements are widely available, others are not. If you have cancer, make sure you take enough of them. Generally 5 to 10 times the normal supplemental amounts seem to work best for food based supplements.

As you can see, this natural approach to cancer is based on making the body healthier. It works on reversing the basic conditions that allow cancer to develop. Strengthening a depleted, worn out, under energized immune system that is not capable of killing cancer cells faster than they are multiplying. And changing the internal body environment so that the cancer cells have a harder time surviving because the conditions that allow them to grow so prolifically have changed.

One final thing, too many people wait too long before getting started on safe and natural supplements for cancer or don’t work up to using enough of whatever supplement they are taking and they don’t make it. Fighting cancer can be a race with time if the cancer is pretty far along. No one knows the minimum amount needed to recover from cancer. The longer the time you have to experiment, the smaller amounts you can try at first. However, if one is seriously ill, it is better to err on the side of taking more than you may really need, because no one knows the minimum amount that is really needed and ones guess may be too little. Especially if chemo is effecting the body. Whole food supplements can't hurt you, they only help! And they don’t make surgery, radiation, or chemotherapy less effective either, in fact it is quite the reverse. The nutritional benefits may vary from one person to another, but everyone will benefit.

OPTIONAL... All Natural Cancer Therapy on 3.5" Floppy

Yep, This All Natural Cancer Therapy web site is available for order on 3.5" Floppy Disk. Disk Includes: A neat little program of ALL of our informational WebSites. The program is simple and easy to use. If you like our websites, you will love this program. It's GREAT... Feel free to make copies to share with family and friends. The information contained could very well be a life saver. System Requirements: 3½ Floppy [A:] Drive. Only... $15.00 How to Order... Click Here

Disclaimer

Always consult your physician. These products have not been approved by the FDA for medical use; consequently, no medical claims can be made. Also, these products must be considered a supplement. Anyone contemplating using these products for medical use must accept such use as experimental and voluntary, and use at their own risk. ( 1 ) No claims are made regarding the therapeutic use of these products. ( 2 ) These statements have not been evaluated by the Food and Drug Administration. ( 3 ) These products are not intended to diagnose, treat, cure or prevent any disease... Feel free to print ( for educational purposes ) any information from this website that you would like to share with family and friends. See the... Rescuing Hug

apple_sparkle.gif (3031 bytes)
“Eat the whole Apple,
seeds ( B17 ) and all”

“Other Vitamin's That Fight Cancer”
Vitamin Supplement for Cancer

“Yep, Your Body's Own Perfect Medicine”
Urine Therapy, Read all about it

“Only the cancer victim himself can
properly treat his own cancer” - Dr. William Kelley
One Answer to Cancer | Cancer Self-Treatment

“Recommended reading”
Oxygen and Cancer | Oxygen Therapy vs. Cancer

“Everything you want to know about Magnetic Therapy”
Magnetic Therapy for Alkaline / High Oxygen

“Total healing of chronic illness only takes place when and if
the blood is restored to a normal, slightly alkaline pH” - Dr. Enderlein
Understanding pH Balance

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http://web.archive.org/web/20070828221422/http://home.bluegrass.net/~jclark/b17_dosage.htm

Mark said...

Why Use Vaccine for HPV When Green Tea Works?

A botanical ointment containing a green tea extract called sinecatechins is an effective treatment for external genital and anal warts, according to the results of a controlled study.

Genital and anal warts are caused by human papillomavirus (HPV), and there has been a lack of effective, well tolerated treatments.

Researchers assigned over 500 adults with 30 warts to either sinecatechins ointment or a placebo. In the sinecatechins groups, warts cleared completely in roughly 57 percent of patients, compared to just 34 percent of subjects in the control group.

Sources:

* Reuters June 6, 2008

* Obstetrics and Gynecology, June 2008; 111(6):1371-1379

Dr. Mercola's Comments:

There are more than 100 types of human papillomaviruses (HPVs).

Of them, only 10-30 can cause cervical cancer. The rest can lead to skin infections that cause genital warts or common warts on your hands and feet.

Although these are very common viruses, and an estimated 25 million Americans have HPV infections, there’s actually little cause for alarm because, as the Centers for Disease Control and Prevention states, “In 90 percent of cases, your body’s immune system clears the HPV infection naturally within two years.”

This is true whether the infection is the type that can cause warts or cancer.

And as you will see, simple alternatives exist in lieu of more dangerous alternatives to battle this common virus.

The Many Healing Powers of Green Tea

Green tea catechins are a class of polyphenols, which are naturally occurring antioxidants. The health benefits of epigallocatechin gallate (EGCG) -- the main active component of tea polyphenol's biological activity – are plentiful, including the prevention of:

* Alzheimer’s disease
* High blood lipid
* Arteriosclerosis
* Cerebral thrombus
* Prostate cancer
* Heart attack and stroke

Other research has found that you can increase the benefits of drinking green tea by adding vitamin C as it boosts the amount of catechins available for your body to absorb. In fact, citrus juice increased available catechin levels by more than five times, causing 80 percent of tea's catechins to remain bioavailable.

Green tea has even been found to have fat-burning properties, and now we can add topical green tea catechins for the treatment of genital warts to the growing list of its healing and health-inducing properties.

Which is a great thing considering the unacceptable -- to me, and many other natural health experts -- alternative of the HPV vaccine.

Do You Understand the Risks of the HPV Vaccine?

The marketers of Merck’s HPV vaccine Gardasil would like you to believe that getting your daughter vaccinated can save her from HPV related illnesses like cervical cancer and genital warts.

Nothing could be further from the truth!

First of all, the Gardasil vaccine contains just four types of HPV out of the more than 100 strains. If you contract one of the 96+ types that aren’t included, you’re out of luck. And, if you’ve already been exposed to one of the four types of virus in the vaccine, it doesn’t work against those either.

So, even if you accept the risks and get vaccinated, your chances of getting some form of HPV are still very high. Whether or not the HPV virus will lead to genital warts or cervical cancer, however, depends in large part on the state of your immune system.

Personally, I don’t see how the mediocre-at-best benefits of Gardasil could possibly outweigh its risks.

As of last October, 3,461 complaints about Gardasil had been filed with the FDA's Vaccine Adverse Event Report System (VAERS), and 11 girls had died after exposure to the vaccine.

I just checked the VAERS database as I sat down to write this article, and it now contains 6,760 adverse event reports, and 16 deaths. The numbers just continue to get worse.

Get a Clue!!

In my neck of the woods they call this increase a giant clue. So if you haven’t already figured out to avoid this vaccine you will want to do more homework. Another point to consider is that you can’t sue the vaccine manufacturer if your child dies.

These companies have cleverly manipulated the government so they are immune from prosecution and have made the U.S. taxpayers foot the bill for the hundreds of millions of dollars that are paid out to families of children who are harmed or killed every year from vaccines.

Even though it is incredibly difficult -- nearly impossible -- to get one of these payments, there have already been more than $1.5 billion dollars given to affected families. So ponder on these stats if you haven’t already taken a firm position on the vaccine issue.

How Does HPV Vaccine Kill?

The causes of death include blood clots, acute respiratory failure, cardiac arrest, and “sudden death” due to “unknown causes” shortly after receiving the vaccine. Clearly, no one knows the full extent of the biological harm that this vaccine inflicts. But I think most people would agree that teenagers don’t normally drop dead of natural causes.

Even more disturbing is the fact that these numbers don’t seem to shock or dismay officials. They’re “consistent with those expected from any vaccine.”

According to the American Cancer Society, some 3,870 women will die from cervical cancer in the U.S. in 2008. Well. We’ve already lost 16 girls, some as young as 12, in the effort to spare them from the possibility of cervical cancer later in life.

Surely I’m not the only one who sees that as morally reprehensible! And how many people have ever died from genital warts?

Cervical Cancer Virtually 100% Avoidable

Cervical cancer is well documented to be caused by an infection acquired through sexual contact. So it is behaviorally avoidable.

According to a New England Journal of Medicine study, the use of condoms reduces the incidence of HPV by 70 percent, offering FAR better protection than Gardasil.

According to the CDC, HPV is the most common sexually transmitted disease in America. More than 6 million women contract it annually, yet as I already mentioned, less than 3,900 women die from cervical cancer out of those 6 million.

Why?

Because your immune system is usually strong enough to clear up this kind of infection on its own, and does so in more than 90 percent of all cases.

Rather than subjecting your daughter (and now possibly your son!) to this unnecessary and potentially dangerous vaccine, you may want to nip the problem in the bud before it ever starts. Here’s how:

* Recognize that cervical cancer (or any cancer) is not caused by a “vaccine deficiency.”

* Talk to your kids about HPV. This infection is sexually transmitted, so it is 100 percent preventable through lifestyle choices.

* Realize the power of your emotions. An emerging school of thought called German New Medicine (GNM) shows how specific stressful events or “conflict shocks” trigger cancer and other diseases in your body.

Dr. Ryke Geerd Hamer, who developed GNM, believes that cancer is a phase that occurs while your body heals itself from this emotional trauma, and that the key to overcoming the disease lies in resolving your emotional conflicts.

* Keep your immune system strong. A healthy immune system is better able to handle a heavier emotional and physical stress load. The ideal healthy habits to keep your body and mind strong are detailed in these 12 changes that will cut your cancer risk in half.


Related Articles:

Gardasil -- New Video Reveals Hidden Dangers

The HPV Vaccine: Preventive Care or Human Sacrifice?

Doctors in Denial About Vaccine Reactions?

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http://articles.mercola.com/sites/articles/archive/2008/06/24/why-use-vaccine-for-hpv-when-green-tea-works.aspx?source=nl

Mark said...

B17 and pancreatic enzymes in the treatment of cancer.

from defunct webpage:
http://web.archive.org/web/20070816190416rn_1/home.bluegrass.net/~jclark/vitamin_b17.htm

THERE IS NO CURE FOR CANCER, but there is a natural treatment for cancer! As you will see treating cancer with a combination of vitamin B17 ( laetrile ) and pancreatic enzymes as part of a total nutritional program has and can rid the body of cancer.

The results of such treatment and evidence is overwhelming which is why this information has been posted. Cancer is a metabolic disease which only the body can remove with the appropriate nutritional program. The nutritional program will help the body rid itself of cancer, but will not cure cancer, because if the nutritional program is stopped the cancer will come back! A cure implies it will never come back.

Just like Scurvy, Berri-Berri and Pellagra, cancer is a nutritional defiency disease. Stop consuming foods with vitamin C and you will develop scurvy. Stop consuming food with vitamin B and you will develop pellagra. Stop consuming food with nitrilosides (vitamin B17) and you will develop cancer.

And this is exactly what has happened in our modern life.

Cancer is BEST treated with a total nutritional program consisting of diet, vitamins, minerals, laetrile and pancreatic enzymes.

Fruits, vegetables, supplementation and detoxification are key.

The reader must use his own discretion and research this for himself. A qualified medical practitioner should always be consulted in the matter of treatment decisions for any cancer.

Vitamin B17 100 mgVitamin B17 500 mg
The Cyto-Pharma B17 — 100 mg and 500 mg Label
( Cyto Pharma de Mexico, has not changed their Image, Labels or Logo.)

Is Vitamin B17 Legal in the USA?

The Cyto-Pharma B17 available in 100 mg and 500 mg tablets.

There are many brands of Amygdalin, Laetrile or Vitamin B17 on the market, but not all of them contain the quality, purity and the structure to be named Amygdalin.

In 1971, Cyto Pharma de Mexico was the first company to receive a license (under the direct supervision of Dr. Krebs, the vitamin B17 discoverer, which included his formula, process, technology and control methods) to produce Amigdalina (Amygdalin) which is the laboratory name for Vitamin B17 or Laetrile. Order your vitamin B17 food supplement from a trusted source.

We carry this vitamin in tablet form, 100 mg and 500 mg tablets. They are 100% pure fruit seed extract from Cyto Pharma de Mexico.

They are the pioneers of the seed extraction of vitamin B17 for over 34 years... The Cyto Pharma de Mexico is the oldest and worlds largest producer of this amazing substance.

They are the only ones who have followed Dr. Krebs exact specifications for the production of vitamin B17. For this reason... We offer Vitamin B17 from Cyto-Pharma, only! Vitamin B17 Suggested Dosage... Click Here

Vitamin B17 100 mg (100 tablets) ..... $40.00 ORDER
Vitamin B17 500 mg (100 tablets) ... $120.00 ORDER

FREE Shipping with Mail-in Orders ( USA Orders Only )

stop_sign.gif (1332 bytes) Lets stop here for a moment... You have heard it said: "You are what you eat." Yes, I eat a good diet, take dietary supplements and I am still sick. Why? You are NOT what you eat. You Are What Your Body Absorbs !!! Is your body being blocked from Vitamin and Mineral absorption? Learn how to cleanse your Small Intestine... Click Here

AND / OR

If you have a health problem, most likely you are acidic. Research shows that unless the body's pH level is slightly alkaline, the body cannot heal itself. So no matter what type of modality you choose to use to take care of your health problem, it won't be effective until the pH level is up.

If your body's pH is not balanced, you cannot effectively assimilate vitamins, minerals and food supplements.

Understanding pH Level... Click Here

For more information... Click Here
Omnizyme Forte
Digestive Enzymes - 200 Tablets

Digestive enzymes also called pancreatic enzymes include three classes of enzymes.

1. Proteolytic enzymes needed to digest protein,

2. Lipases needed to digest fat and

3. Amylases needed to digest carbohydrates.

Pancreatin as a digestive enzyme is available from any health food store in the country, however this type of pancreatin is useless for the cancer patient. The active ingredients in pancreatin which have shown to have tumor dissolving abilities are — trypsin and chymotrypsin.

We carry only the most potent pancreatin, that have high levels of trypsin and chymotrypsin... More Information and Supplement Facts... Click Here

Omnizyme Forte ( with 125 mg Trypsin and 45 mg Chymotrypsin ) 200 tablets.

Simply the BEST Proteolytic Enzymes available in the world today, bar none !!!!

Omnizyme Forte Enzymes (200 tablets) ... $65.00 ORDER

FREE Shipping with Mail-in Orders ( USA Orders Only )

Note: No claims are made regarding the therapeutic use of these products...
These statements have not been evaluated by the Food & Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

---
http://web.archive.org/web/20070816190416rn_1/home.bluegrass.net/~jclark/vitamin_b17.htm

Mark said...

Cleansing The Small Intestine

from defunct webpage:
http://web.archive.org/web/20070817083955rn_1/home.bluegrass.net/~jclark/small_intestine.htm

Here is a book you may want to read... Dr. Kelley’s One Answer to Cancer

If there were only one kind of pill that would help everybody, the cancer patient or otherwise, it would be "Okra-Pepsin-E3" made by Standard Process, Inc.

It would probably do the nation’s health more good than any other one pill. It digests the mucus that coats the walls of many people’s small intestine. Certain foods, such as pasteurized milk and many cooked foods, cause the mucus buildup on the wall of the small intestine (raw foods do not cause this mucus buildup). The mucus coats the villi on the wall of the small intestine. The villi are like tiny fingers that stick out from the intestinal wall to absorb nutrients from the digested food, which is primarily liquid. The mucus on the villi blocks the absorption of nutrients from the food. Sometimes the mucus gets so thick and tough it is almost like a plastic film. Almost no nutrition can get through to the body. A person with a severe mucus buildup could take $1,000.00 worth of supplements a month along with a good diet and still get almost no nutritional value from them. He or she would be starving and therefore would want to eat more food including protein.

That would lead to more of the pancreatic enzymes being used to digest the protein even though it could not be properly absorbed.

When all the pancreatic enzymes are used up, there are none left in the blood to destroy cancer cells.

The Okra is a very sticky, gooey, vegetable material. It tends to stick the Pepsin enzyme to the mucus on the intestinal wall long enough to digest some of the mucus.

The E-3 is a powerful tissue repair factor. It was originally developed for the patient with stomach ulcers or colitis.

If the Okra-Pepsin-E3 capsules are taken for a few days to several weeks, one after each meal ( reduce the amount of capsules if diarrhea occurs ), the mucus will gradually be digested. The blood can then receive more nutrients from the food, even if it is from a poor diet. Then, once a year, take the Okra-Pepsin-E3 capsules again for a few days or a week to keep the mucus from building back up.

The mucus blockage varies with different people. Sometimes it blocks minerals and larger molecules only, while in other people it partially blocks all nutrients.

While taking the Okra-Pepsin-E3 capsules people who have heavily mucus-coated intestines might find mucus coming out with their stool, convoluted like the intestines.

Dr. Kelley has had people who have been taking the capsules call him to say that they think they have just passed their intestines and what should they do? ( He assures them it wasn’t their intestines; it was ropes — or tubes — of mucus! )

One 37-year-old patient called Dr. Kelley to report that the Okra-Pepsin-E3 capsules worked a miracle by relieving reoccurring pain that she had suffered with for years. The pain would come and go apparently without cause and felt like bricks were pressing against her internal organs and lower back and at the same time her right side and leg would feel numb. On the morning of the eighth day, after taking one Okra-Pepsin-E3 capsule with each meal for a week, she spent 45 minutes sweating, straining and pushing to have a bowel movement, and when it finally came out she could hardly believe what she saw — long, intertwined black ropes ( or collapsed tubes ) of mucus filled the toilet! She feels lighter now and hasn’t had the pain since that day. After this bowel movement and the disappearance of her pain she realized that there must have been a connection to eating a large meal and the pain — food passing through the intestine would push the mucus-coated intestine onto nerves, which caused the pain and numbnes.

The Okra-Pepsin-E3 is indicated for both underweight and overweight people. In both cases nutrients are not being absorbed. Even if they are taking enzymes to digest the food they eat, they absorb only the smaller carbohydrate molecules while the larger protein molecules are blocked. In underweight people the carbohydrates are used efficiently ( burned for energy, not turned into fat ), but the person becomes thin as they lose muscle mass from lack of protein absorption. In overweight people the carbohydrates are not used efficiently ( they are turned into fat ), and this causes the person to become overweight as they also lose muscle mass.

Metamucil™ ( Pysllium husks ), one or two tablespoons daily, mixed with water or juice, may be taken to sweep the mucus out of the colon once it is broken down by the pepsin in the Okra-Pepsin-E3 capsules.

You have learned the old saying "You are what you eat" is incorrect. You are NOT what you eat, but rather You are what your body absorbs !

Proper Digestion, Absorption, and Assimilation...
Six ( 6 ) Critical facts:

1. Researchers now believe that 90% of ALL DISORDERS and DISEASES begin in the digestive tract due in large to improper digestion, absorption, and assimilation of nutrients. In short, proper digestion, absorption, and assimilation of nutrition equals = Optimum Prevention.

2. Every cell, tissue, bone, gland, and organ of the body needs to be fueled and nourished by nutrients. Without proper assimilation of nutrients, all components of the body will deteriorate prematurely and potentially become diseased.

3. Disorders and diseases of the digestive tract must not be left untreated. Proper digestion, absorption, and assimilation of nutrients must be assured in order to recover from present disease in the digestive tract, or anywhere throughout the body.

4. It is common knowledge among many researchers that the body's natural defense mechanism against disease ( the immune system ) is highly dependent upon the absorption of nutrition to fuel it's function. Without proper absorption of essential nutrients, the immune system is unable to ward off potential disease or to effectively battle against existing conditions. Therefore, the body's ability to fight disease, or to recover from disease without significant essential nutrients is for the most part, impossible. Nutrients are a "Vital Key" and the body must be in a position to absorb them.

5. 99% of all pharmaceutical drugs do not heal or cure, they merely "hide" or "mask" symptoms WHICH LEAVES THE CAUSATIVE FACTORS INTACT.

6. If you have a health problem, most likely you are acidic. Research shows that unless the body's pH level is slightly alkaline, the body cannot heal itself. So, no matter what type of modality you choose to use to take care of your health problem, it won't be effective until the pH level is up. If your body's pH is not balanced, you cannot effectively assimilate vitamins, minerals and food supplements. Understanding pH Level... Click Here

To Order
"Okra-Pepsin-E3"

Okra-Pepsin-E3 is designed to reduce irritation of the intestinal tract and aid in digestion. If the patient has any irritation in the gastrointestinal tract, this product will heal it. Okra-Pepsin-E3 is an excellent healing and cleansing agent. A positive urine Indican test, colitis, indigestion, dry hard bowel movements, and low stomach acid often call for Okra-Pepsin-E3.



Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 40 or 150 Capsules
Amount Per Serving

Calories .......................................... 1
Cholesterol ..................................... 5 mg
Proprietary Blend ....................... 227 mg
Okra, Tillandsia usneoides extract, bovine orchic extract, pepsin (1:10,000), carbamide, alginic acid, and allantoin.

Other Ingredients: Gelatin, lactose, water, calcium stearate, and natural colors.

Allantoin, a primary ingredient in Okra-Pepsin-E3, has been known to promote skin health. The properties of the combined nutrients in Okra-Pepsin-E3 also give this product bowel-cleansing capabilities.

Each capsule supplies 100 mg okra powder, 20 mg pepsin (1:10,000), and 15 mg tillandsia extract. Suggested Use: One capsule after each meal, or as directed.



okra_pepsin.jpg (6225 bytes)
Okra-Pepsin-E3

Okra-Pepsin-E3 ( 40 capsules ) ..... $25.00 ORDER
Okra-Pepsin-E3 ( 150 capsules ) ... $60.00 ORDER

FREE Shipping with Mail-in Orders ( USA Orders Only )



Note: No claims are made regarding the therapeutic use of this product... Plus,
These statements have not been evaluated by the Food & Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

---
http://web.archive.org/web/20070817083955rn_1/home.bluegrass.net/~jclark/small_intestine.htm

Mark said...

[As if it requires saying, I have nothing financial to do with this. These are just succinct webpages of human bodily health. You can get these materials from many locations besides these products obviously. However, for the knowledge, it is valuable. It is unlikely you will be told about this if you go the route of 'treat the symptoms' forms of allopathic medicine and the risky, expensive drug companies and their paid-off doctors that get commissions to peddle the corporation's drugs.]

Coral Calcium and pH Balance

Understanding pH Level and Why Many
People Have Disease, Including Cancer.


According to the research of Dr. Enderlein, total healing of chronic illness only takes place when and if the blood is restored to a normal, slightly alkaline pH. In case you missed it, let me say it again...

Total healing of chronic illness only takes place when and
if the blood is restored to a normal, slightly alkaline pH.


pH: What does it mean? pH is the abbreviation for potential hydrogen. The pH of any solution is the measure of its hydrogen-ion concentration. The higher the pH reading, the more alkaline and oxygen rich the fluid is. The lower the pH reading, the more acidic and oxygen deprived the fluid is. The pH range is from 0 to 14, with 7.0 being neutral. Anything above 7.0 is alkaline, anything below 7.0 is considered acidic.

The pH scale is from 0 - 14

0 1 2 3 4 5 6 7 healthy 8 9 10 11 12 13 14

Human blood stays in a very narrow pH range right around ( 7.35 - 7.45 ).

Below or above this range means symptoms and disease. If blood pH moves to much below 6.8 or above 7.8, cells stop functioning and the patient dies.

The ideal pH for blood is 7.4

A healthy blood pH without cancer has acid + alkaline balance almost equal. Actually a healthy body is slightly alkaline measuring approximately 7.4.

This ideal blood 7.4 pH measurement means it is just slightly more alkaline than acid.

0 is acid ------ blood pH ( 7.35 - 7.45 ) healthy ------ over 7 to 14 is alkaline

If you have a health problem, most likely you are acidic. Research shows that unless the body's pH level is slightly alkaline, the body cannot heal itself. So, no matter what type of modality you choose to use to take care of your health problem, it won't be effective until the pH level is up.

If your body's pH is not balanced, you cannot effectively assimilate vitamins, minerals and food supplements. Your body pH affects everything.

The body has to have a balanced pH like most living things on earth or it does not function correctly.

The alkaline level is very important because research has already proven that disease cannot survive in an alkaline state and yet they thrive in an acidic environment.

An acidic balance will: decrease the body's ability to absorb minerals and other nutrients, decrease the energy production in the cells, decrease it's ability to repair damaged cells, decrease it's ability to detoxify heavy metals, make tumor cells thrive, and make it more susceptible to fatigue and illness.

An acidic pH can occur from, an acid forming diet, emotional stress, toxic overload, and/or immune reactions or any process that deprives the cells of oxygen and other nutrients. The body will try to compensate for acidic pH by using alkaline minerals. If the diet does not contain enough minerals to compensate, a build up of acids in the cells will occur.

There are two factors that are ALWAYS present with cancer no matter what else may be present.

Those two factors are Acid pH and Lack of Oxygen.


Can we manipulate those two factors that always have to be present for cancer to develop and by doing so will that help reverse the cancer? If so, we need to learn how to manipulate those two factors.

Cancer needs an acid and low oxygen environment to survive and flourish within. Terminal cancer patients are around 1000 times more acidic than normal healthy people.

The vast majority of terminal cancer patients possess a very low body pH. Why?

In the absence of oxygen, glucose undergoes fermentation to lactic acid.


This causes the pH of the cell to drop from between 7.3 to 7.2 down to 7 and later to 6.5 in more advanced stages of cancer and in metastases the pH drops to 6.0 and even 5.7 or lower. Our bodies simply can not fight disease if our body pH is not properly balanced.

The normal human cell has a lot of molecular oxygen and a slightly alkaline pH. The cancer cell has an acid pH and lack of oxygen. Cancer cells cannot survive in an oxygen rich environment. At a pH slightly above 7.4 cancer cells become dormant and at pH 8.5 cancer cells will die while healthy cells will live. Again, the higher the pH reading, the more alkaline and oxygen rich the fluid is.

Cancer and all diseases hate oxygen / pH balance. The proper alkalinity pH of the blood ( 7.35 - 7.45 ) is critical for the overall health of the body. In other words... alkalize or die.

Remember that the pH number is an exponent number of 10; therefore, a small difference in pH translates to a big difference in the number of oxygen (i.e., really OH-ions.)

A difference of 1 in a pH value means ten times the difference in the number of OH-ions, a difference of 2 means one hundred times the difference in the number of OH-ions.

In other words, blood with a pH value of 7.45 contains 64.9% more oxygen than blood with a pH value of 7.30.

Fact: If your body's pH is not balanced, you cannot effectively assimilate vitamins, minerals and food supplements. Also, mucus on the small intestine can block your body from vitamin and mineral absorption. Learn how to cleanse the Small Intestine... Click Here

How To Test Your pH Level...YOURSELF

Test your pH level: If you are sick or have cancer simply wet a piece of Litmus Paper with your saliva 2 hours after a meal. This will give a reflection of your state of health.

Salivary pH Test: While generally more acidic than blood, salivary pH mirrors the blood ( if not around meals ) and is also a fairly good indicator of health. It tells us what the body retains. Salivary pH is a fair indicator of the health of the extracellular fluids and their alkaline mineral reserves.

Optimal pH for saliva is 6.4 to 6.8. Spit upon arising before anything is put into the mouth. A reading lower than 6.4 is indicative of insufficient alkaline reserves. After eating, the saliva pH should rise to 7.8 or higher. Unless this occurs, the body has alkaline mineral deficiencies ( mainly Calcium and Magnesium ) and will not assimilate food very well.

To deviate from ideal salivary pH for an extended time invites illness.

Acidosis, an extended time in the acid pH state, can result in rheumatoid arthritis, diabetes, lupus, tuberculosis, osteoporosis, high blood pressure, most cancers and many more. If salivary pH stays too low, the diet should focus on fruit, vegetables and mineral water as well as remove strong acidifiers such as sodas, whole wheat and red meat.

Urinary pH Test: The pH of the urine indicates how the body is working to maintain the proper pH of the blood. The urine reveals the alkaline building (anabolic) and acid tearing down (catabolic) cycles. The pH of urine indicates the efforts of the body via the kidneys, adrenals, lungs and gonads to regulate pH through the buffer salts and hormones. Urine can provide a fairly accurate picture of body chemistry, because the kidneys filter out the buffer salts of pH regulation and provide values based on what the body is eliminating. Urine pH can vary from around 4.5 to 9.0 for its extremes, but the ideal range is 5.8 to 6.8.

Foods considered to be alkaline-forming and thus helpful to people with consistently acid pH include: almonds, aloe vera, apples, apricots, bee pollen, buckwheat, cabbage, cantaloupe [most cantloupes have huge amount of pesticides--if you want this go organic], celery, carrots, cucumbers, dairy products except hard cheese, dates, dulse, poached eggs, figs, grapefruit, honey, lettuce, millet, parsley, raisins, peaches, fresh red potatoes, pineapple, soy products, sprouted seeds, cooked spinach, turnip tops, wakame miso soup, azuki beans, rice, mineral water. More alkaline-forming foods... Click Here

[However, know that sometimes depending on the person's metabolic type, people can have different reactions to the same foods. Get about a book about metabolic typing.]

People who remain too acid often display symptoms such as: anxiety, diarrhea, dilated pupils, extroverted behavior, fatigue in early morning, headaches, hyperactivity, hypersexuality, insomnia, nervousness, rapid heartbeat, restless legs, shortness of breath, strong appetite, high blood pressure, warm dry hands and feet.

Balancing the pH is a major step toward well-being and greater health. Acidosis ( overly acidic body ) is the primary indicator of Calcium Deficiency Disease.

Scientists have discovered that the body fluids of healthy people are alkaline ( high pH ) whereas the body fluids of sick people are acidic ( low pH ). Coral Calcium and drinking high pH alkaline natural spring or mineral water can help balance your body pH.

Amazing Coral Calcium
( Coral Calcium from Okinawa ) [though it hardly matters the source--you can get more Ca+ ions from anything...)

Over 200 diseases are linked to
Ionic Calcium Deficiency Disease (ICDD):


Cancer, Diabetes, Arthritis, Heart Disease, Osteoporosis, Eczema, Alzheimer's Disease, Fibromyalgia, High Cholesterol, Muscle Cramps, Kidney Stones, Gallstones, Gout, Indigestion, Chronic Fatigue Syndrome, Lupus, Hiatal Hernia, Hypertension, Heartburn, High Blood Pressure, Acne, and many, many more.

Coral Calcium and drinking oxygen rich spring or mineral water with a high pH factor, combined with minerals and other elements, can help provide our body the natural ability to fight off disease.

Scientists have discovered that a low level of oxygen in the body can disrupt the body's ability to function normally and at the same time can severely cripple the immune system, leaving your body vulnerable to disease and premature aging.

Coral Calcium greatly increases the oxygen level in the body, thereby allowing the body to rid itself of toxic waste that continues to build up. That's why when you indulge yourself in "junk food" the body diverts oxygen away from the primary metabolic functions and works overtime trying to digest your high caloric intake. That's why when you eat junk food or large meals you feel sluggish afterwards.

Your body literally slows down its metabolism to compensate for the overload.

Is your body oxygen poor? Here are a few signs to look for:

muscle aches * poor digestion * dizziness * depression * irrational behavior * weakness * acid stomach * irritability * memory loss * circulation problems

Louis Pasteur said before he died: The germ is nothing. The "terrain" is everything. Coral Calcium doesn't cure disease. It simply helps keep the pH level of our body fluids in sync so the body fights disease naturally, like it was meant to. Coral Calcium and drinking high pH alkaline water will definitely help our body's "terrain" in preventing and/or curing disease.

In other words, a body with a balanced pH is a deadly environment for all disease, including cancer.

What Coral Calcium can do for you...

* Maintain optimum alkalinity for optimum health

* Provide you easily absorbed and usable calcium

* Cleanse the kidneys, intestines and liver

* Maintain stronger bones and healthier teeth

* Alleviate insomnia

* Keep your heart beating regularly

* Help metabolize your body's iron

* Aid your nervous system

* Breakdown heavy metals and drug residues in your body

* Neutralize harmful acids that lead to illness

* Achieve a healthy alkaline level, neutralizing acid

* Protect your body from free radical damage

* Control digestive problems

* Increase muscle and joint mobility

* Combat arthritic conditions and heart disease

* Regulate blood sugar levels and blood pressure

The Ultimate Alkalinity Therapy
High pH Alkaline Water - Coral Calcium - Digestive Enzymes - Alkaline Forming Foods

How to drink for MAXIMUM effectiveness:

Drink ½ your body weight of water in ounces, daily. Example: 180 lb = 90 oz. of water daily. Divide that into 8 or 10 oz. glasses and that's how many glasses you will need to drink, daily. Use ¼ tsp. of Sea salt (celtic sea salt being the highest in mineral content [though much of the sea is polluted...]) as seaoning on your food for every quart of water you drink. As long as you drink the water, you can use the salt. Avoid caffeinated or alcoholic drinks. These are diuretics and will dehydrate you. Every 6 oz. of caffeine or alcohol requires an additional 10 to 12 oz. of water to re-hydrate you. Interesting Facts About Water and Salt... Click Here

The Minimum Recommendations For Water: ( Use Sea salt same as above )
Drink a minimum of 64 ounces ( about 2 liters ) of water every day. I know this is easier said than done. Don't wait until you're thirsty to drink - you'll likely never get this much down. Instead, keep filled water bottles at your desk, in your car, by your bed, and near your favorite chair as a reminder. A lot of information and testimonials... Click Here

[ If you have congestive heart failure or kidney disease, or if you are taking diuretics, talk to your doctor before increasing your water intake.]

Coral Calcium has a pH of 10-12 which is extremely high on the alkalinizing side. This means coral calcium will help offset the acid / alkaline ratio within your acidic body, thereby will help return your body to the normal slightly alkaline level.

Suggested Dosage: See Chart, below.

Digestive Enzymes: Very few are aware of the real functions of enzymes in the body. We strongly recommend adding Digestive Enzymes to your Alkalinity Therapy and for very good reason. IF YOU WOULD LIKE TO LEARN THE TRUE PURPOSE OF ENZYMES AND HOW IMPORTANT THEY ARE... Click Here Plus, it may be a good ideal to add Vitamin B17 ( 500 mg ) and/or Apricot Kernels to your Alkalinity Therapy for cancer.

Vitamin B17 Suggested Dosage... Click Here

To maintain health, the diet should consist of 60% alkaline forming foods and 40% acid forming foods. To restore health, the diet should consist of 80% alkaline forming foods and 20% acid forming foods. A list of Acid / Alkaline Forming Foods... Click Here [though the effect can be different in different metabolic types, I have read.]


Our Coral Calcium (1100 mg capsules)
Your pH level Suggestions to Increase Your pH
below 6.0 1 capsule, 7 times daily = 7700 mg
6.0 - 6.5 1 capsule, 5 times daily = 5500 mg
7.0 or higher 1 capsule, 3 times daily = 3300 mg

Which Coral Calcium is Best for Optimum Nutrition?.. Click Here


WARNING: IF YOU ARE DRINKING DIET SODAS WHICH CONTAIN ASPARTAME OR USING SUGAR-FREE PRODUCTS - READ THIS!! Diet sodas, foods labeled as "sugarless" "sugar free" "diet foods" "low calorie" and the like - You had better be careful and read the label to see if they contain ASPARTAME. Please check labels carefully Aspartame is poison and extremely acid forming. Take the 60 day aspartame test. Give up all aspartame for 60 days and note the improvements in your health. Check it out... Do internet search on "aspartame and/or diet cola". [ note in Australia ( and UK ) who just have numbers on things - not names - Aspartame is 951 ]

Note: Again, if you have congestive heart failure or kidney disease, or if you are taking diuretics, talk to your doctor before increasing your water intake. Feel free to print any information from this website that you would like to share with family and friends. See.. The Rescuing Hug

Coral Calcium ( 1100 mg. capsules ) Supplement Facts Click Here

FREE Shipping with Mail-in Orders ( USA Orders Only )



Note: No claims are made regarding the therapeutic use of this product... Plus,
These statements have not been evaluated by the Food & Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

---
http://web.archive.org/web/20070816190546rn_1/home.bluegrass.net/~jclark/coral_calcium.htm

Mark said...

[My same caveat above applies.]

Omnizyme Forte Digestive Enzymes
pH-sensitive, enteric coated tablet
Omnizyme Forte are the most potent and effective proteolytic enzymes available - bar none!

from defunct webpage:
http://web.archive.org/web/20061207185534rn_1/home.bluegrass.net/~jclark/ph_sensitive.htm


Since most enzymes can be easily destroyed by stomach acid, our enzymes have a special pH sensitive coating that is not digestible by stomach acid, but is sensitive to the alkaline environment of the duodenum, thereby insuring complete survival of all of the enzymes. Since nutrients are absorbed in the duodenum, this is by far the most efficient way to deliver proteolytic ( protein digesting enzymes ) to your system.

This is one product that is best delivered in a tablet form. Since stomach acid is highly destructive to pancreatic enzymes and to most plant source enzymes and since capsules are quickly broken down in the stomach, the use of capsules with enzymes is simply put, a bad idea. For most nutrients, passing through the stomach does no harm and in some cases is helpful and even necessary, but it is not good for enzymes.

Since capsules can not be enteric coated, any enzyme formula in a capsule form is likely to be of a greatly diminished value. Also beware of the term " enteric coated ". An enteric coating is a coating that is placed over the tablet to protect it's contents. However, unless it says "pH sensitive" before enteric coating, you may be getting a protein coating. Protein coatings work to a limited degree. The protein coating can be digested by stomach acid, thereby destroying enzymes. Sometimes they survive the stomach and unfortunately the duodenum as well, allowing the tablet to pass through the system undigested.

We have a high potency, pH sensitive enteric coated enzyme formula. Which content Chymotrypsin an extremely potent pancreatic enzyme of which much has been written. It's activity is so great that most enzyme formulas on the market only contain 1/2 to 1 milligram. Our Omnizyme Forte formula contains 45 milligrams of Chymotrypsin along with the other enzymes and synergistic nutrients.

Omnizyme Forte are the most potent and effective proteolytic enzymes available - bar none! Originally designed for clinical use, these indispensable aids are now available for use by everyone. Proteolytic enzymes have long been used for a variety of ailments with nearly miraculous results reported. Everything from digestive disorders to sports injuries to heart and circulatory disorders to neoplastic diseases ( a progressive uncontrolled new growth of tissue ) better known as cancer have been treated not only successfully, but sometimes with spectacular results.

These formulas were designed by professionals with over 28 years in the medical and nutritional supplementation fields and 25 years experience in the use of enzyme therapies. They have been manufactured with specially chosen coatings and potent enzyme activators and anti-inhibitors to assure maximum absorption of the product in its most active state so that maximum systemic performance is achieved.

Omnizyme Forte was the first and remains one of the few enzyme supplements to contain 45 mg of highly active Chymotrypsin, one of the most potent and long-lived enzymes available for oral supplementation. The cost of this potent, but expensive enzyme is reflected in the price. This product is our biggest seller by far and for very good reason! ( Positive Results )

Back to Omnizyme Forte

Note: No claims are made regarding the therapeutic use of this product... Plus,
These statements have not been evaluated by the Food & Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.


---
http://web.archive.org/web/20061207185534rn_1/home.bluegrass.net/~jclark/ph_sensitive.htm

Mark said...

Interesting Facts About Water and Salt

Salt Intake is Vital

Salt is vital to the extraction of excess acidity from the cells in the body, particularly the brain cells.

from defunct webpage:
http://web.archive.org/web/20070529222604rn_1/home.bluegrass.net/~jclark/water_salt.htm

Salt is a vital substance for the survival of all living creatures, particularly humans. Water and salt regulate the water content of the body. Water itself regulates the water content of the interior of the cell by working its way into all of the cells it reaches.

It has to get there to cleanse and extract the toxic wastes of cell metabolisms. Salt forces some water to stay outside the cells.

It balances the amount of water that stays outside the cells. There are two oceans of water in the body; one ocean is held inside the cells of the body, and the other ocean is held outside the cells [intercellular fluid]. Good health depends on a most delicate balance between the volume of these oceans, and this balance is achieved by salt - unrefined salt.

When water is available to get inside the cells freely, it is filtered from the outside salty ocean and injected into the cells that are being overworked despite their water shortage. This is the reason why in severe dehydration we develop an edema and retain water.

The design of our bodies is such that the extent of the ocean of water outside the cells is expanded to have the extra water available for filtration and emergency injection into vital cells.

The brain commands an increase in salt and water retention by the kidneys. This is how we get an edema when we don't drink enough water.

Initially, the process of water filtration and its delivery into the cells is more efficient at night when the body is horizontal.

The collected water, that mostly pools in the legs, does not have to fight the force of gravity to get onto the blood circulation. If reliance of this process of emergency hydration of some cells continues for long, the lungs begin to get waterlogged at night, and breathing becomes difficult.

The person needs more pillows to sit upright to sleep. This condition is the consequence of dehydration. However, you might overload the system by drinking too much water at the beginning.

Increases in water intake must be slow and spread out until urine production begins to increase at the same rate that you drink water.

When we drink enough water to pass clear urine, we also pass out a lot of the salt that was held back.

This is how we can get rid of edema fluid in the body; by drinking more water. Not diuretics, but more water!!

In people who have an extensive edema and show signs of their heart beginning to have irregular or very rapid beats with least effort, the increase in water intake should be gradual and spaced out, but not withheld from the body. Naturally, salt intake should be limited for two or three days because the body is still in an overdrive mode to retain it. Once the edema has cleared up, salt should not be withheld from the body.

Salt has many other functions than just regulating the water content of the body. Here are some of the more vital functions of salt in the body:

1. Salt is most effective in stabilizing irregular heartbeats and, contrary to the misconception that it causes high blood pressure, it is actually essential for the regulation of blood pressure - in conjunction with water. Naturally the proportions are critical.

2. Salt is vital to the extraction of excess acidity from the cells in the body, particularly the brain cells.

3. Salt is vital for balancing the sugar levels in the blood; a needed element in diabetics.

4. Salt is vital for the generation of hydroelectric energy in cells in the body. It is used for local power generation at the sites of energy need by the cells.

5. Salt is vital to the nerve cells' communication and information processing all the time that the brain cells work, from the moment of conception to death.

6. Salt is vital for absorption of food particles through the intestinal tract.

7. Salt is vital for the clearance of the lungs of mucus plugs and sticky phlegm, particularly in asthma and cystic fibrosis.

8. Salt is vital for clearing up catarrh and congestion of the sinuses.

9. Salt is a strong natural antihistamine.

10. Salt is essential for the prevention of muscle cramps.

11. Salt is vital to prevent excess saliva production to the point that it flows out of the mouth during sleep. Needing to constantly mop up excess saliva indicates salt shortage.

12. Salt is absolutely vital to making the structure of bones firm. Osteoporosis, in a major way, is a result of salt and water shortage in the body.

13. Salt is vital for sleep regulation. It is a natural hypnotic.

14. Salt is a vitally needed element in the treatment of diabetics.

15. Salt on the tongue will stop persistent dry coughs.

16. Salt is vital for the prevention of gout and gouty arthritis.

17. Salt is vital for maintaining sexuality and libido.

18. Salt is vital for preventing varicose veins and spider veins on the legs and thighs.

19. Salt is vital to the communication and information processing nerve cells the entire time that the brain cells work - from the moment of conception to death.

20. Salt is vital for reducing a double chin. When the body is short of salt, it means the body really is short of water. The salivary glands sense the salt shortage and are obliged to produce more saliva to lubricate the act of chewing and swallowing and also to supply the stomach with water that it needs for breaking down foods. Circulation to the salivary glands increases and the blood vessels become "leaky" in order to supply the glands with water to manufacture saliva. The "leakiness" spills beyond the area of the glands themselves, causing increased bulk under the skin of the chin, the cheeks and into the neck.

21. Sea salt contains about 80 mineral elements that the body needs. Some of these elements are needed in trace amounts. Unrefined sea salt is a better choice of salt than other types of salt on the market. Ordinary table salt that is bought in the super markets has been stripped of its companion elements and contains additive elements such as aluminum silicate to keep it powdery and porous. Aluminum is a very toxic element in our nervous system. It is implicated as one of the primary causes of Alzheimer's disease.

22. Twenty-seven percent of the body's salt is in the bones. Osteoporosis results when the body needs more salt and takes it from the body. Bones are twenty-two percent water. Is it not obvious what happens to the bones when we're deficient in salt or water or both.

The information on salt intake is taken from Dr. Batmanghelidj's book, "Water: Rx for a Healthier Pain-Free Life". http://www.watercure2.com

TOP ESSENTIALS of LIFE

1. Oxygen 2. Water 3. Salt 4. Potassium 5. Exercise

FACT - No one can live without these. Mainstream medicine too often ignores 2 and 3 in favor of selling drugs and procedures to treat the symptoms of dehydration.

FACT - Nothing kills life quicker than lack of water.

FACT - The people with the worst health drink the least water and use the most deadly diuretic drought causing drugs - caffeine and/or alcohol.

FACT - The salinity of the water outside the cells in our bodies is the same as the ocean.

FACT - In the middle ages people were put to a horrible death by salt deprivation.

FACT - Health care makes big bucks by selling a quart of water with salt in it (Saline 4) for up to $350.00 installed, but won't tell the patients they do indeed need more water and salt in their diets.

FACT - How can you expect drug companies to do research on the importance of water in our daily lives when they can't make money on it? Who does research to put themselves out of business?

FACT - No two substances in the Bible are mentioned more than water and salt.

FACT - The environment of an unborn baby is water and salt.

---
http://web.archive.org/web/20070529222604rn_1/home.bluegrass.net/~jclark/water_salt.htm

Mark said...

The Mediterranean Diet Can Stop Diabetes

from:
http://articles.mercola.com/sites/articles/archive/2008/06/21/the-mediterranean-diet-can-stop-diabetes.aspx?source=nl

A Mediterranean-style diet rich in vegetables is already known to protect against heart disease. Now, researchers have found that it also appears to help ward off diabetes.

A four-year study of 13,000 people showed that those who stuck closely to the diet were 83 percent less likely to develop type 2 diabetes.

Even those who smoked, were older, and had a family history of diabetes experienced protective benefits from the Mediterranean diet.

The World Health Organization estimates more than 180 million people worldwide have diabetes. This number is likely to more than double by 2030, as more nations adopt a Western lifestyle.

Sources:

* Reuters May 29, 2008

* British Medical Journal May 29, 2008


...

Dr. Mercola's Comments:

The Mediterranean diet is in many ways leaps and bounds better than the standard American diet. It includes plenty of olive oil for one, whereas many Americans are still afraid of fat. It also emphasizes fresh vegetables, something most people could use more of.

And it downplays processed foods, which make up the majority of the typical diet in the United States.

That the Mediterranean diet can be good for you has been well established. Studies have shown that it can:

* Reduce your risk of cancer
* Improve arthritis
* Help people with Alzheimer’s live longer
* Protect against heart disease
* Even lower your death rate

So should you jump on to the Mediterranean bandwagon and adopt this increasingly popular diet?

No way.

Even the Mediterranean Diet Has Some Flaws

There are several glaring errors that come to mind when I think about the "heart-healthy" Mediterranean diet.

1. It promotes the misguided notion that saturated fats are bad for you.

Like the U.S. food pyramid, the Mediterranean diet vilifies saturated fats. Things like red meats and eggs, according to the diet, should be eaten sparingly. Saturated fats, however, have been wrongly blamed for the epidemics of heart disease and obesity. In reality, these healthy animal fats are necessary and very good for you.

2. It encourages eating many grains.

Bread, pasta, rice, potatoes and other grains are emphasized in the Mediterranean diet. Never mind that these are the exact items (along with vegetable oils and sugars) that have significantly contributed to heart disease, diabetes and obesity spiraling out of control in the United States. A small portion of people, perhaps one-third, can thrive on a diet like this one that encourages whole grains. But what about the rest of us?

You can read my other article on insulin to find out if you are someone that needs to avoid many or most grains.

3. One diet could never be right for everyone.

You have an individual nutritional type that dictates which foods are healthy for you. Those foods may or may not be the same ones that are healthy for your spouse, your neighbor or your best friend. So while a carb nutritional type may do very well on the Mediterranean diet, a protein type would feel lousy because there simply isn’t enough red meat and fat to sustain them.

What else concerns me about the Mediterranean diet is its reckless promotion of fish and seafood.

Healthy?

Yes, in theory, because it contains beneficial omega-3 fats.

But today our waterways are polluted, which means most fish is polluted too. And if you’re eating farm-raised fish, that’s an even worse option. So while I believe you should definitely get omega-3 fats in your diet, I recommend doing so through an animal-based omega-3 supplement like krill oil. This way you get the benefits without the pollution.

Also worthy of note, while cheese, yogurt and other dairy are popular foods in this diet, there is no mention of getting them raw, which is a key part of making them healthy.

Of course, in many regions overseas dairy products are still widely available unpasteurized, so it may be more of an American issue to clarify the importance of eating dairy products raw. [Why? See the 'dentistry' category at commodity ecology...]

The Rise of the “Med Mark”

The latest of food labeling schemes to hit the market is the “Med Mark,” (right) a stamp for food labels that helps you identify foods that are part of the Mediterranean diet.

The stamp is the work of Oldways, a non-profit “food issues think tank” that also was behind the Whole Grains Stamp released in 2005.

Should you keep an eye out for foods with this stamp?

It depends.

On some levels, it’s a good thing. Products that have the stamp are supposed to be minimally processed or “meet stringent health standards” including having zero trans fats and limited sodium and sugar content. As is typical, saturated fats (the incorrect scapegoat) are also supposed to be limited.

As of March 2008, the Med Mark appeared on over 100 food items, and this is expected to rise to 300 by the end of the year.

I can tell you right now that the majority of these food items are probably not that healthy. The exceptions would be foods like extra virgin olive oil, avocados and olives … natural food products in their original form.

What you will surely begin to see, though, will be shelves of pasta, bread, dips, soups, pasta sauce and other processed foods with this Med Mark attached. And processed foods are not ideal choices for your health.

So do feel free to pick and choose from the healthy elements of the Mediterranean diet, but also feel free to bypass those that are not.

For Those of You With Diabetes …

The benefit found in the above study likely came from the use of healthy fats and increased veggies -- NOT from the large amount of grains. For people with diabetes, the last thing you want to be eating is a lot of grains, or any for that matter.

Swap out your grains and sugar for high-quality sources of protein, healthy fat (which INCLUDES saturated fat) and vegetables, and you’ll be off to a great start.

Add in regular exercise, the other essential key to preventing and reversing diabetes, and you’ll be even better off.

Related Articles:

Will the Modified Mediterranean Diet Extend Your Life?

Hummus -- One Healthy Food Fighting for School Cafeteria Space

Mediterranean Diet Lowers Death Rate

---
http://articles.mercola.com/sites/articles/archive/2008/06/21/the-mediterranean-diet-can-stop-diabetes.aspx?source=nl


More mercola sales stuff:


You probably know that I normally don’t promote many supplements. I believe that supplements should complement your healthy diet and never serve as a replacement.

There’s simply no substitute for eating healthy unprocessed whole foods.

However, there are a few supplements I consider highly beneficial for nearly all adults. One of these is Coenzyme Q10 (CoQ10).

CoQ10 exists in every cell in your body.

And CoQ10 is critical in generating the energy “currency” of all your cells, adenosine triphosphate (ATP)*. In other words, your cells require CoQ10 to help produce the energy you need to live.*

But as you age, your levels of CoQ10 naturally diminish.

And even if you do your very best to eat wholesome unprocessed foods, your body’s capability to produce Co Q10, critical for your energy production, declines over time.*

So, one very important reason for using a CoQ10 supplement is to help boost your body’s fundamental energy level.*

And there are many other ways CoQ10 can help you. As you age and your CoQ10 levels decline, oxidative insults to your cells start accumulating. This can promote the typical signs of aging.

So you need a smart way to help turn this process around…

How to Help Turn Your Declining CoQ10 Levels into a Healthier YOU*

Here’s how CoQ10 can help you in many different ways to complement your healthy diet and energize your life:

Helps you produce more energy for your cells*

CoQ10 & Ubiquinol

* Acts as a catalyst in your body’s various chemical reactions, leading to the production of energy.*

* Ignites your body’s engine by jump-starting energy production in your cells.*

* You’ll enjoy your new-found energy and stamina levels.*

Boosts your heart health*

* Helps strengthen your overall cardiovascular system.*

* Helps maintain and balance the critical energy level needed in your body’s most vital muscle… your heart.*

* Since you’re passionate about life, you need an optimally-functioning heart.*

Acts as an antioxidant to help protect you from free radicals*

* Provides your body with added defense against oxidation stress to your cells, tissues, and organs.*

* Helps recharge other antioxidant nutrients to their active states — and keeps them working for you.*

* You’ll feel good about yourself, knowing you’re taking steps to live a healthy life.*

Helps you reduce the signs of normal aging*

* Helps you potentially feel more alert and responsive.*

* By keeping blood levels high in CoQ10, helps you maintain your vitality.*

* You’re determined to feel young and full of life… don’t let aging get the best of you.*

Helps you maintain blood pressure levels within the normal range*

* Promotes healthy blood circulation in your body and a more efficient heart.*

* Research indicates maintaining proper levels of CoQ10 can help you maintain normal blood pressure levels.*

* Just by knowing you’re taking more steps to take control of your health, you could feel more relaxed and less stressed out.*

Provides a boost to your immune system*

* Helps promote your healthy immune system.*

* Helps support your immune system by providing a defense against free radicals.*

* You’ll feel great about yourself knowing you’re taking action to potentially boost your immune system.*

Supports your nervous system*

* Helps promote an active mind.*

* Your brain is one of the most active organs in your body and requires uninterrupted energy.*

* Nothing beats having an active mind to help you deal with all of life’s challenges — and to help you make healthy decisions for your family.*

By now, you should see the power of CoQ10, and understand why I believe it provides you with extraordinary benefits to complement your healthy diet.*

There’s another very strong reason to take CoQ10…

Why You Should Replenish Your CoQ10 Levels When Taking Statin Drugs

If you or anyone you know is taking a statin drug, I truly believe it is absolutely essential to start taking a CoQ10 supplement immediately to replenish your CoQ10 levels.
cells

Statin drugs work to lower your cholesterol in the same pathway your body uses to produce CoQ10

Why?

Statin drugs work to lower your cholesterol in the same pathway your body uses to produce CoQ10.

Now you might ask: “Why would you take a statin drug in the first place?”

Good question.

Normally, I believe well over 99% of people placed on statin drugs do not need them (although you should always consult a physician before stopping any medication).

I believe people should be able to easily optimize their cholesterol levels with simple lifestyle changes.

However, I have been practicing medicine for far too long to know the journey to good health can be long and complex for many. Some people simply require more time to make the transitions in weaning off these dangerous drugs.

So if you or someone you care about is taking a statin, I recommend that you start using a high quality CoQ10 supplement right away.

But not just any CoQ10 supplement.

To be in line with my mission to provide you only the best, you should…

Never, Ever Settle for 2nd Best

As with any supplement I recommend on my site, I established stringent criteria to find you the ultimate CoQ10 formula.

This thorough process ensures you can take full advantage of all the benefits the supplement has to offer.

My strict criteria for selecting a top-notch CoQ10 supplement for you?

It must:

* Deliver a high-absorption formula regardless of your age

* Be all-natural with NO synthetic ingredients

* Come from a highly reputable company with some of the strictest quality control and safety standard practices in place

So, let’s jump into the amazing formula I found in the form of…

Ubiquitous Ubiquinol… Everywhere in Your Life

When I set out to find a top-notch CoQ10 supplement for my subscribers, I quickly found an endless sea of brands and choices available.

However, I discovered that a recent scientific breakthrough now makes an advanced form of the nutrient available… a form I believe is superior.

Grandparents

Critical Co Q 10 levels decline as you age. So I believe this is a must-have supplement!

You see, CoQ10 by itself is also known as ubiquinone. To benefit from the form of the nutrient needed to produce cellular energy, your body must convert the ubiquinone to ubiquinol.

Ubiquinol exists everywhere there is life… it’s ubiquitous!

The challenge you face as you age is this — your body levels of CoQ10 continue to diminish.

In addition, your capability to convert CoQ10 to ubiquinol also declines. It becomes more and more difficult for you to produce the ubiquinol you need to keep your energy level high.*

With the Mercola Advanced Nutrition supplement, you now can have the ubiquinol formula direct… the active form of the CoQ10 nutrient.

This form can be significantly more absorbable than ordinary ubiquinone*.

The reason is quite simple. With ubiquinol you’re not as dependent on your body to convert ubiquinone to ubiquinol… it’s already in the active state your body needs.

However, not everyone needs the ubiquinol formula. If you’re younger, your body should absorb regular Co Q10 just fine.

In fact, research studies show that younger people don’t absorb ubiquinol as well as older folks. So, if you’re young, sticking to a regular formula makes more sense.

That’s why I decided to offer both regular CoQ10 and ubiquinol-based CoQ10 in my line of Mercola Advanced Nutrition supplements.

But I’m not done yet. Here are even more advantages you’ll get from using the Mercola Advanced Nutrition CoQ10 supplements and…

Why These Formulas Stand Above the Rest

As you’ve already seen, using a high-quality CoQ10 supplement provides you great benefits:*

And in my opinion, statin drug users should begin taking the supplement immediately to help replenish their CoQ10 levels.
With my Mercola Advanced Nutrition CoQ10 supplements, there are even more possible advantages for you in the way they…

* Support healthy gums*
* Boost your body’s immune system*
* Help maintain normal blood sugar levels*
* Support muscle recovery from intensive workouts*
* Promote normalization of your weight*

It gets even better, as my Mercola Advanced Nutrition Co Q10 supplements are…

100% Natural, Without Any Synthetics

A very exclusive process drives the creation of these supplements. A unique manufacturing process using biological fermentation delivers a 100% pure and natural CoQ10.

This is right in line with one of my most stringent selection criteria.

This process not only ensures you get a 100% natural product, but a stabilized, high-absorption formula as well.

One of the biggest challenges faced by any manufacturer of ubiquinol is how it easily oxidizes in the air. This adds to the instability of the nutrient.

To overcome this issue, the manufacturer of the Mercola Advanced Nutrition CoQ10 supplements actually established technology that enables the production of ubiquinol in stable bulk quantities.

This results in a 100% natural formula that achieves higher elevations of circulating CoQ10 in your bloodstream.*

With all the amazing benefits of the Mercola Advanced Nutrition CoQ10 supplements…

Click to view Larger label
Ubiquinol
CoQ10

Why Would You Settle for Inferior Quality?

As you probably already know from other supplements I offer on my site, it’s not enough that the product itself is superior to others.

The developer and manufacturer of CoQ10 must also demonstrate proven quality practices.

There are literally hundreds, if not thousands, of CoQ10 supplements on the market today… but there are only a few great ones out there… and even fewer provide the advanced ubiquinol formula.

If the importance of using CoQ10 is convincing to you, than I would strongly encourage you to do your homework, and make sure a GREAT company produced it.

When I first started my investigation, the low quality demonstrated by so many companies absolutely shocked me.

That’s why I spent many long months researching to identify what I believe is one of the top CoQ10 supplement manufacturers in the U.S. today.

Here’s why I firmly believe the manufacturer of the Mercola Advanced Nutrition CoQ10 supplements clearly stands apart in quality standard practices:

* Completed FDA notification of ubiquinol product as a New Dietary Ingredient (NDI) – unique position by this CoQ10 manufacturer
* Follows strict Pharmaceutical GMP standards in its manufacturing processes
* Awarded and filed applications on at least 24 US and international patents – including 10 for its CoQ10 ubiquinol manufacturing process
* Announced self-affirmed GRAS (Generally Recognized as Safe) status

This manufacturer performed all necessary research and provided supporting materials regarding production methods, quality assurance, and safety – no objection letter was issued.
* Delivers Kosher certified product – No animal-derived products exist in the CoQ10 products or can find their way into the raw materials during the manufacturing process.

You should clearly see why I chose this manufacturer to provide you with the highest quality Mercola Advanced Nutrition supplements.

Don’t ever settle for a supplement unless it is solidly backed by a manufacturer practicing the highest quality standards.

To you, quality means a consistent top-of-the-line product every time you use it.

How High-Quality Means Exceptional Value You Can Rely On

The scientific community continues to conduct many research studies using CoQ10 in both ubiquinone and ubiquinol forms.

To date, the safety and reliability reports on the supplement remain solid.

This should always be important to you when considering taking any supplement… I know it is for me.

* From the American Cancer Society: “Few serious reactions to CoQ10 have been reported.”
* From the University of Maryland Medical Center: “Coenzyme Q10 appears to be generally safe with no significant side effects…”
* From the National Center for Complementary and Alternative Medicine (NCCAM) at the National Institutes of Health (NIH): “No serious side effects have been reported from the use of coenzyme Q10.”

I bet you agree — this is excellent feedback on CoQ10 safety.

With the superior high-quality practices in place for the Mercola Advanced Nutrition CoQ10 supplements, I feel these are true winners.

And here are…

5 Clear-Cut Reasons For You to Act Now

Now you should understand why I’m so excited to bring you these extraordinary CoQ10 supplements. They passed all of my stringent selection criteria for supplements to be offered on my site.

Let me quickly summarize all this for you with 5 clear-cut reasons why you should take action and order these supplements without delay.

The Mercola Advanced Nutrition CoQ10 supplements can:

1Boost your energy and stamina levels*

1Support the health of your cardiovascular system*

1Help you feel younger and reduce the normal signs of aging*

1Enhance the support of your immune and nervous systems*

1Replenish your CoQ10 levels if you’re taking a statin drug*

The Time for Action is Now – It’s Guaranteed

Isn’t it time you took action and ordered one of the Mercola Advanced Nutrition CoQ10 supplements today?

If you’re using a statin, I sincerely believe you need to take a CoQ10 supplement to replenish your CoQ10 levels.

With my thorough and methodical research, I’ve taken all your guesswork out of finding the ultimate high-quality, regular and ubiquinol-based CoQ10 supplements.

With the Mercola Advanced Nutrition Co Q10 supplements, you know you will benefit from:

* 100% all-natural non-synthetic formulas
* Highly-absorbable CoQ10 available in both regular and ubiquinol formulas
* Consistent products backed by a manufacturer with exceptional high-quality standard practices
* Supplements with proven reliability
* A 100% lifetime guarantee

When it comes to CoQ10, I’ve simply not found better products for your money than the Mercola Advanced Nutrition supplements.

If you believe you’ve found even better ones, please let me know by contacting my customer service department. Remember, I always strive to provide the best possible products to you.
But please don’t be fooled by other supplements not backed by quality manufacturing and not offering an ubiquinol-based formula.

I’m so convinced my Mercola Advanced Nutrition Co Q10 supplements are superb products to help energize your life and complement your healthy diet… I’m offering you a 100% lifetime guarantee (see details below).

At only $16.97, for the regular CoQ10 formula, and $44.97 for the ubiquinol formula.

So, don’t delay any longer, order your Mercola Advanced Nutrition CoQ10 supplement today!

Isn’t it time you ‘energized’ your life?*

---
http://products.mercola.com/coq10-ubiquinol/?source=nl

Mark said...

Removing Metal Toxcity and the Techniques

Metal Toxicity

by Dietrich Klinghardt, MD, Ph.D.

In the late phase of the Roman Empire, it was considered a privilege of the reigning aristocracy to drink out of lead cups and many of the water lines in the city of Rome were made out of lead pipes. It took several hundred years before the physicians of the time established the link between mental illness -- affecting mostly the aristocracy -- and the contamination of the drinking water with lead.

In the 1700s, the use of mercury for the treatment of both acute and chronic infections gained favor and again, it took decades before the neuro-toxic and immuno-suppressive effects of mercury were well documented within the medical community.

In the time of Mozart, who died of mercury toxicity during a course of treatment for syphilis, any pathologist in Vienna was familiar with the severe grayish discoloration of organs in those who died from mercury toxicity and other organ-related destructive changes caused by mercury.

In the case of mercury, the therapeutic dilemma is most clear. Mercury can be used to treat infections, but -- not unlike chemotherapy -- also causes a different type of illness and may kill the patient.

The same is true for most metals; small doses may have a therapeutic effect for a short term, life saving direction, but may also cause their own illness.

Most metals have a very narrow therapeutic margin before their neuro-toxic (and in some cases carcinogenic effect), outweigh the benefits. Toxic metals may be fungicidal and bactericidal, maybe even virucidal, but many foreign invaders have the ability to adapt over time to a toxic metal environment in a way that stuns scientists and certainly outpaces the ability of the cells of a higher organism -- like ours -- to adapt in a similar way.

In the long run, the situation looks different. Toxic metals harm the cells of the body whereas the invading microorganisms can often thrive in a heavy metal environment.

Research by Ludwig, Voll and others in Germany and by Omura and myself here in the US, show that microorganisms tend to set up their housekeeping in those body compartments that have the highest pollution with toxic metals.

The body's own immune cells are incapacitated in those areas whereas the microorganisms multiply and thrive in an undisturbed way.

The teeth, jawbone, Peyers patches in the gutwall, the ground-system (connective tissue) and the autonomic ganglia are common sites of metal storage and the place where microorganisms thrive.

Furthermore, those bodily areas are also vasoconstricted and hypoperfused by blood, nutrients and oxygen, which foster the growth of anaerobic germs, fungi and viruses.

The list of symptoms of mercury toxicity alone, published by DAMS (Dental Amalgam Support Group) includes virtually all illnesses known to humankind.

Chronic fatigue, depression and joint pains are the most common on the list.

To keep it simple, mercury alone can mimic or cause any illness currently known or at least contribute to it.

Modern medicine has taken a giant leap in the past few years through the discovery and use of the PCR test (polymerase chain reaction). Virtually any illness seems to be caused or contributed to by a chronic infection.

A study performed by the VA Administration (published in JADA, April 1998) on 10,000 US veterans, showed that most coronary heart disease really started as an endothelial infection and, in most cases was caused by microorganisms from the mouth.

Another study showed that close to 70% of all TMJ syndromes in women are caused or contributed to by chlamydia trachomatis.

Childhood diabetes is often caused by either a cytomegalovirus or influenza virus infection.

I suggest diagnosing and treating toxic metal residues in the body along with the appropriate treatment of the microorganisms.

As long as compartmentalized toxic metals are present in the body, microorganisms have a fortress that cannot be conquered by antibiotics, Enderlein remedies, ozone therapy, UV light therapy and others.

To diagnose metal deposits in the different body compartments on a living patient is not easy. Most "scientific" tests are based on grinding up tissue and then examining it with a microscope, spectroscopy or other laboratory-based procedures.

The most elegant, suitable and easy to learn system is Dr. Yoshiaki Omura's resonance phenomenon between identical substances. Both his bi-digital O-ring test or ART (autonomic response testing) are extensions of a regular physical exam that can be done without any instruments. It is a very accurate diagnostic tool and makes it possible to not only diagnose where in the body which metal is stored, but also helps to predict which metal detoxifying agent is most suitable to remove the toxic metal from that particular body region.

The metals found most commonly are:

* mercury
* lead
* aluminum
* cadmium

Among the detoxifying agents most commonly used are DMPS, DMSA, Captomer, D-Penicillamine, I.V. vitamin C, I. V. Gluthathione, Pleo-Chelate, DL-Methionine (Redoxal), branched chain amino acids, Chlorella Pyreneidosa, Chitosan, activated charcoal, cilantro and yellow dock. [and zeolite]

I have developed non-biochemical approaches and include electromobilization (using the Electro-Bloc), mercury vapor lamp mobilization and others.

The approach to treating illness in a way that acknowledges those observations has to include the following:

Diagnosing the site of toxic metal compartmentalization

Diagnosing the exact type of metal

Determining the most appropriate and least toxic metal removal agent

Determining other appropriate synergistic methods and agents (i.e., kidney drainage remedies, blood protective agents -- garlic or vitamin E, agents that increase fecal absorption and excretion of mobilized Hg, exercise, lymphatic drainage, etc.)

Diagnosing the secondary infection

Determining an appropriate antibiotic regimen (medical antibiotics, antifungals, antivirals, Enderlein remedies, ozone therapy, etc.)

Monitoring the patient carefully form visit to visit to respond quickly to untoward effects most often caused by plugged up exit routes.

With this approach, many patients that were chronically ill and did not respond to other approaches will improve or get well.

However, the thoughts expressed thus far do not answer one important question.

Why do patients that are exposed to mercury, deposit the toxin in various areas of their body?

Some deposit the mercury in their hypothalamus (and develop multiple hormone problems), or in their limbic system (depression). Others deposit it in the adrenals (fatigue), or in the long bones (osteoporosis, leukemia). Some in the pelvis (interstitial cystitis), in the autonomic and sensory ganglia (chronic pain syndromes); some in the connective tissue (scleroderma, lupus), or in the cranial nerves (tinnitus, cataracts, TMJ problems, loss of smell), or in the muscles (fibromyalgia).

As you would assume, multiple causes can be identified.

Past physical trauma (such as closed head injury) will make the brain susceptible to becoming a storage site for lead, aluminum and mercury.

Food allergies often cause a low-grade encephalitis or joint inflammation, setting up those areas to become targets for toxic deposits.

Geopathic stress -- Significant numbers of patients were found sleeping on underground water lines or too close to electrical equipment. Metals concentrate in the body regions most compromised.

Scars and other foci can create abnormal electrical signals that can alter the function of the ANS (autonomic nervous system). The abnormal impulses often cause areas of vasoconstriction and hypoperfusion, which again become metal storage sites.

Structural abnormalities -- TMJ problems and cranio-sacral dysfunctions often are responsible for impairment of blood flow and lymphatic drainage in affected areas.

Biochemical deficiencies -- If the patient has a chronic zinc deficiency, the prostate, which has a large turnover of zinc, starts to incorporate other 2-valent metals (such as Hg++, Pb++).

Environmental toxicity (solvents, pesticides, wood preservatives, etc.) has a synergistic effect with most toxic metals. Metals will often accumulate in body parts that have been chemically injured at a prior time.

Unresolved psycho-emotional trauma and unresolved problems in the family system.

This last cause -- unresolved psycho-emotional trauma -- is by far the most common factor determining where which metal will be stored in the body and which infectious agent will thrive in what area of the body. This issue has been underestimated by most, due to a lack of appropriate, quick and precise therapeutic interventions.

I have developed a type of biofeedback psychotherapy called psychoneurobiology (APN).

The core of this approach is the dialogue with the subconscious mind. Any type of ART technique (muscle testing, EAV, brainwave biofeedback, etc.) may be used to obtain answers and engage in the dialogue.

The technique is aimed at uncovering any unresolved past traumatic event and processing the material in a way that is healing to both the patient and their family. The material is covered in the APN I and II handouts and in the video sets from the APN Seminars.

Patients who responded poorly or were unresponsive to prior treatment with appropriately selected Enderlein remedies and detox agents, responded dramatically by treating the patient first with APN, by unloading emotional material, correcting limiting beliefs and creating an opportunity for healing between living and dead family members.

In fact, every parameter of their biochemistry, including bio-terrain measurements like tissue and blood pH, osmolality, conductivity but also including hormone levels, mineral levels, etc. move in a direction toward normal after successful APN treatments. Results are often permanent.

The disease model that is emerging from these observations looks as follows:

The symptom is that which is visible or apparent and usually the reason the patient comes to us. Underneath or within it, we find most often a chronic infection. Underneath the infection, we find the altered milieu -- mostly the presence of toxic metals. Underneath that, the reason why it is there (other than the obvious necessary exposure), the selection of location, the choice of metal -- are all created and guided by the subconscious mind and determined by the type, severity and date of unresolved psycho-emotional trauma or material.

Explore Volume 10, 2000


Dr. Mercola's Comments:

This is a good summary of the general issues one needs to be concerned about in metal toxicity.

For the health care practitioners in the audience I strongly recommend attending Dr. Klinghardt's courses to understand the scientific and practical methods one can use in removing toxic metals such as mercury from the body.

Related Articles:

Dr. Klinghardt's Courses

Upcoming April Course

Mercury Detoxification Protocol

CMV Infection May Induce Atherosclerosis

---
http://articles.mercola.com/sites/articles/archive/2001/03/10/metal-toxicity.aspx


2.


Mercury Detoxification Protocol
http://www.mercola.com/article/mercury/index.htm

1. Diet.

Avoid all sugar and milk, limit all processed foods and most grains, especially wheat. Read the Optimal Wellness Handout http://www.mercola.com/nutritionplan/index.htm

every day for two weeks and follow it. Read the detailed version at least twice.

It will be important to have a high protein diet as the sulfur bearing amino acids in the protein will greatly facilitate detoxification.

Do NOT attempt to fast during DMPS mercury detoxification. If you are a vegetarian you will be at HIGH risk for complications from DMPS unless you have a large amount of protein.

Whey protein can be used as a supplement as it is high in glutathione and branched chain amino acids. Two large tablespoons are used per drink and that can be taken once a day and twice a day for the week prior to DMPS chelation.

Autistic children can't use this product as it contains casein. They can use pure branched chain amino acids. You can start with one capsule twice daily and mix with food. Work up to two capsules twice a day for the week prior to DMPS chelation.

2. Beneficial Bacteria

Take one quarter to one half teaspoon once a day of a high potency high quality strain. It is vital to have an optimized bowel flora for detoxification.

3. Maintain two to three bowel movements per day

If you are not having this many bowel movements make certain that your thyroid status has been checked. It is very common for mercury to affect the thyroid. If your thyroid function is fine then you should add some magnesium.

If you are on long-term magnesium it is important to take some calcium with it or after awhile you will develop an imbalance in your calcium magnesium ratio which could result in severe cramping.

Freshly ground flax seed several teaspoons per day will facilitate intestinal movement and also contribute some healthy essential fatty acids.

4. Unload the connective tissue with Chlorella or ProChitosan.

Chlorella and ProChitosan are an important part of the detoxification program, as approximately 90% of the mercury in our bodies is eliminated through the stool. Chlorella is an algae and, unlike Protchitosan, has protein high levels of chlorophyll and other nutrients which can be used for nourishment.

The chlorella powder is the most cost effective approach but some people will prefer the tablets or capsules for convenience. A simple way to dissolve the powder is to place it in a container with a lid partially filled with water. Then tighten the lid and shake to dissolve and drink the solution.

Caution: About 30% of people can't tolerate chlorella. This may be due to optimized function of the enzyme cellulase. If you are unable to tolerate this it would be wise to consider adding an enzyme with cellulase in it to help digest the chlorella.

Dose: One can start out with a one quarter of a teaspoon of the powder (one 500 mg tablet) once a day initially to confirm that there is no hypersensitivity present. Work up slowly over one to two weeks to a dose of one teaspoon (ten tablets or capsules) per day. Once you tolerate this dose you are able to use it to bind the mercury. Use this dose starting two days prior to your chelation and for one day afterwards. The chlorella will thoroughly coat your intestine and bind like a sponge to any mercury that the DMPS liberates into the gut.

The above dose is based on a 150 pound adult. If you are using the program for children reduce the dose proportionately. (So a 30 pound child would have have 30/150 or 1/5 (20%) of the dose).

Caution: If at any time one develops nausea or starts "burping up" the chlorella taste then the chlorella should be stopped immediately as a food sensitivity is developing which will only worsen if you continue taking it. If this happens you should switch to ProChitosan This binds similarly to mercury. Its dose is dependent on your bowel movements.

If you have one bowel movement a day or less you should start two days prior to the DMPS . If you have two or more bowel movement you can start 24 hours prior to the DMPS. Stay on it for 24 hours after the DMPS. So you will be on it either two or three days. The dose is two capsules three times a day. Be sure to drink it with plenty of water and increase magnesium if constipation develops.

Porphrazyme from Biotics Research is another alternative to chlorella that many clinicians have had success with in mercury detoxification.

5. Start Garlic or MSM. It would be wise to start on garlic regularly to enhance sulfur stores. Use the food, rather than the supplement garlic. Try to get in three cloves per day, but decrease the dose if your odor becomes socially offensive.

Again, as indicated in the chlorella section above, children will have proportionately lower doses.

MSM is a form of sulfur which will help your body to remove the mercury. The initial dose is one capsule twice a day. Increase by one capsule a day until you are at three capsules twice a day. If you have root canals and are chronically sick you may want to increase to five capsules three times a day.

6. Start Cilantro Cilantro will help mobilize mercury out of the tissue so the DMPS can attach to it and allow it to be excreted from the body. The best form of cilantro is a tincture available from Dragon River (505-583-2348).

The dose is one dropper applied on the wrists and rubbed in twice a day for the two weeks preceding the DMPS IV. It is used the morning prior to the DMPS chlelation but can be stopped for the following two weeks. The tincture is also particularly useful for any joint pain and could be rubbed on the joint that is hurting as an alternative.

You can also augment the tincture with using the herb. It is not as potent, but certainly will add to the program. However, like chlorella, many people are sensitive to oral cilantro. So, if you develop any nausea or discomfort after eating cilantro do not use it orally.

7. Mineral Replacement.

It is important to have a generally healthy mineral base. The body works better with toxic metals than no metals at all. Enzymes have certain binding sites that require a metal for them to perform their function as a catalyst. When you are deficient in magnesium, sodium, zinc and other minerals, the body does not let go of the toxic metals very easily.

Selenium and zinc are particularly important trace mineral in mercury detoxification and should be used for most people.

Generally the citrate form of minerals works quite nicely unless one has an low blood phosphorous level. It is important to not take copper or iron though unless a clinician has examined a hair analysis and or blood work and recommended these minerals. Thorne Research has Citramins II which is citrated minerals without copper or iron.

Hydrochloric Acid: If you do not have a sufficient amount of hydrochloric acid secreted by your stomach then it will be very difficult to ionize mineral supplements to absorb them properly. There is a hydrochloric acid reflex present on the lowest rib approximately one inch lateral to the midline. If this area on the rib is tender to palpation there is a strong likelihood the person is deficient in hydrochloric acid and would benefit from supplementation.

This is especially common in individuals over 50 years old, and also in individuals with food allergies. One to six capsules or more of Betaine hydrochloride is generally taken with the first bite of every meal for proper digestive support. The Betaine can be discontinued once the reflex point in non-tender to deep palpation.

Monitoring Your Mineral Dosing

It will be very important to monitor your mineral levels during the detoxification program. This should be done initially and at least every 6-12 weeks. I only recommend two labs to do this work. Trace Elements and Analytical Research as they are the only two labs that do not wash the hair samples prior to analysis.

8. Digestion and Gall Bladder Support

Liver and gallbladder congestion are major issues in states of toxicity. To insure that your gallbladder bile flow is functional add magnesium taurate or taurine, butyric acid (Butryex 559-433-3110)

The dose of the Butyrex initially is 1/8-1/4 of capsule. Gradually increase the dose to 5 capsules 3 times daily. The Butyrex has a offensive odor which is lessened by keeping it in the freezer. Additionally inserting the powder in applesauce, raw honey or elderberry cough syrup may improve compliance.

Digestive enzymes (containing lipase) and CCK (stimulates contraction of the gall bladder. These can be used one hour after meals containing fat.

Your ability to clear toxins will be impaired if you do not have proper fats to support digestive function. Your diet should contain adequate fat from unprocessed pure oils. Omega Nutrition, Flora or Arrowhead Mills

* sunflower
* safflower
* sesame

OR fats naturally found in foods:

* seeds
* nuts
* avocado
* free range organic poultry, eggs, or meats

9. Antioxidants:

Vitamin C and E. It would be wise to take Unique vitamin E one capsule per day and about 250-500 mg of vitamin C with each meal. If you are exercising aggressively you can take 1000 mg of C 15-30 minutes prior to exercising. It is also wise to consider adding 2-4,000 mg of Vitamin C powder to a half gallon of water and drinking that throughout the day.

It will be VERY important to take 2000 units (typically five of the 400 unit capsules) of vitamin E the day of and the day after the DMPS injection as this will decrease the side effects of the detoxification reaction considerably. You can also take 1-2 grams of vitamin C immediately prior to the DMPS injection.

10. Start Monthly DMPS Injections, Suppositories or Transdermal

You should not have DMPS if you still have amalgam fillings. If they have been removed the injections can be started on a monthly basis. Collection of the urine is then down to analyze how much mercury is being excreted. One must urinate completely prior to the injection.

I perform the analysis at 90 minutes as that is most convenient, but others do four or 24 hour collections. The DMPS injections are generally given about six times or until the level drops into single digits or you are feeling better.

For pediatric patients

You can click here to find out why I don't recommend DMSA mercury chelation. [posted below] Since an IV is such a traumatic event for most children it is probably wise to use a rectal suppository version of DMPS which is available from most compounding pharmacists. Another alternative is to apply the dose transdermally with DMSO. This is very similar to the way that the hormone secretin is being used for many autistic patients.

The dose is 5 mg of DMPS per kg of body weight and is generally given once a month. The urine collection for pediatric patients incorporates a bag to collect the urine for mecury analysis.

11. DMPS Alternative

Some people do not tolerate DMPS well. This is especially true for those who have damage in the central nervous system, such as those with MS or ALS or children with fragile brain architecture. If this is the case there are several options. PCA (peptid clathrating agent) spray can be used. The dose is 4 sprays under the tongue every day or every other day. One may use a dipeptide amino acid or mixed mineral succinates such as Champion Nutrition Muscle Nitro.

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http://www.mercola.com/article/mercury/index.htm


3.


Autism and Mercury Detoxification
http://articles.mercola.com/sites/articles/archive/2000/10/01/mercury-autism-part-one.aspx

P. Kane, Ph.D. and J. Mercola, D.O.

Recently, it has been proposed that autism may be the aftermath of exposure to mercury such as ethyl mercury used as a preservative, thimerosal, in pediatric vaccinations. The article in this newsletter issue reviews this evidence.

Currently Recommended Pediatric Mercury Protocol

The protocol is always being improved. Drs. Klinghardt, Kane and Mercola revised this in September 2000 and the most current recommendations can be found by clicking here. Small changes are likely to be regularly posted but we will likely revise the protocol in December when we all are presenters at the Healing Your Brain 2000 Seminar.

We currently are planning to hold a one day workshop at the American Academy of Environmental Medicine and to invite some of the top clinicians in mercury detoxification to further improve the program. Additionally, Wayne Obie, of TalkInternational.com is planning on facilitating an international collaboration on a revised mercury detoxification program.

What is DMSA and Why Don't We Recommend It?

DMSA is a FDA currently approved drug. It is a mixed disulfide in which each of the sulfur atoms is in disulfide linkage with a cysteine molecule forming water soluble chelates which increases the urinary excretion of lead.

There are a number of physicians who have started to use DMSA to remove the mercury from children with autism. The dose used for mercury detoxification is much lower than that for lead and some children seem to have received benefit from this approach.

A time released DMSA has been suggested for 7 days on, 7 days off or 3 days on, 4 days off for an extended period of time (up to 6 months).

However, some natural medicine clinicians have some serious concerns about the use of DMSA. There have been cases of:

seizures

increased self-stimming

and compromised central nervous system function in some children

DMSA and Mercury Redistribution To The Brain

It appears that DMSA and lipoic acid can create tissue redistribution of mercury as decreasing Hg levels in the kidney (the organ accumulating Hg most abundantly) increases Hg concentrations of Hg in blood, brain, lung, heart, muscle and liver (Gregus et al).

Natural medical physicians throughout the US have reported MS symptoms in adults and intractable seizures in pediatric patients with high dose and extended use of DMSA (2, 3-dimercaptosuccinic acid), Chemet or Succimer.

Other Problems With DMSA

Extended use of DMSA can cause mild to moderate neutropenia with increased SGOT, SGPT, Platelet count, Cholesterol, Alkaline Phosphatase and Blood Urea Nitrogen (BUN). Adverse reactions to DMSA include ataxia, convulsions, rash, nausea, diarrhea, anorexia, headache, dizziness, sensorimotor neuropathy, decreased urination, arrhythmia, infection. Zinc excretion doubles during the administration of DMSA. Patients must be kept hydrated as renal function can be compromised.

For the above described reasons, in good conscience, we cannot recommend the use of DMSA for the treatment of mercury toxic pediatric patients.

Approaching the fragile brain architecture of young children with autism, PDD and seizure disorders brings about tremendous responsibility in protecting the children from invasive interventions that risk alteration in brain function.

DMPS Recommended Chelating Agent

The physicians who support the use of DMSA claim that they do not use DMPS because it is an unapproved drug and the cost.

Both of these concerns are not valid as DMPS has undergone phase one and two FDA trials and has been approved for use distribution in bulk form by compounding pharmacists. Phase 3 trials were not completed due to lack of funding.

The medical literature favors DMPS over DMSA as the drug of choice. Challenge doses of DMSA to determine heavy metal load are often unremarkable as DMSA is a weak chelator. DMPS yields clinically useful spills of mercury and other heavy metals into the urine.

Dose for dose DMSA costs much less than DMPS. But since the DMPS is only used once per month, the total cost is actually significantly lower than DMSA which must be used 28 times per month.

Hair Analysis For Diagnosis and Treatment

First, a determination must be made if, in fact, there is a heavy metal burden and if so specifically which heavy metals are involved such as aluminum, mercury, lead or others.

This is the reason why hair analysis is a recommended initial screen. At this time we only advise two labs for this determination. Trace Elements in Austin, Texas and Analytical Research in Arizona.

Both of these labs do not wash the hair samples prior to analysis. This is a key factor to proper interpretation of the other nontoxic minerals.

Other labs would likely give proper heavy metal results, but the interpretation of the other minerals is key to an effective supplementation program. Chelation removes other minerals aside from mercury and these must be replaced properly if one wishes to avoid complications.

Establishing Metabolic Stability Prior To Detoxification

One must be relatively healthy to sustain the process of detoxification. Once metabolic stability is established physicians often find that gentle biological interventions clear heavy metal burdens without the need for medication that holds the potential risk of negative side effects or merely redistribution of heavy metals.

Clearing heavy metals may be approached by first reestablishing the mineral base, supporting biliary function/ digestion, insuring the patient is properly hydrated (children with autism are frequently dehydrated), and most importantly supporting hepatic function and metabolism

Adults with heavy metal toxicity generally have significant suppression of omega 6 arachidonic acid and a significant elevation of very long chain fatty acids (Kane) as the cellular impact of heavy metals burdens block receptor sites such as G proteins and ultimately suppress the beta oxidation of lipids and cellular respiration.

Children with autism consistently have an elevation of very long chain fatty acids. However, red cell lipid levels of arachidonic are variable, elevated in some patients while deeply suppressed in others.

Dietary Fat Intervention Must Be Considered

Administration of fish oils suppresses omega 6 and structural lipids and this will suppress the production of arachidonic acid. To balance fat metabolism it is crucial to stabilize omega 6 fatty acids and arachidonic acid before introducing omega 3 lipids.

Patient outcomes may be compromised if one uses fish oils prior to omega 6 fatty acids. The omega 6 fatty acid of choice would be evening primrose oil. Additionally, supporting the digestion of fats with bile salts and lipase is frequently required to maximize fat absorption and digestion.

Japan and Mercury Exposure Example

The impact of Hg upon human health was brought to light in the mid-50s with the Minamata disaster in Japan. As noted in the documentary 'Message to Minamata to the World' the impact of mercury is devastating, most prominently to the CNS. Interestingly, autistic behavior can observed in the documentary of Minamata children in original footage after the disaster.

In 1993 Kane found an interesting correlation in the literature between autism and mercury with the occurrence of autism presenting in adulthood occurring in Japan. The presentation of autism in these individuals was linked to ornithine transcarbamylase deficiency, the most common urea cycle defect. Damage to this enzyme can occur with exposure to mercury.

Low levels of ornithine transcarbamylase (OTC) leads to states of hyperammonemia, seizures and stroke. The enzyme OTC controls ammonia, critical issues in states of epilepsy and autism. The often spacy, confused behavior 'brain fog' that is frequently observed in these disorders may be attributed states of hyperammonemia as ammonia reaches the brain.

Suggested treatment of mildly suppressed levels of OTC includes sodium benzoate and phenylacetate. However, Kane and other clinicians have observed positive clinical usefulness of Ca/Mg butyrate, digestive intervention targeted to biliary flow, appropriate buffers, and stabilization of electrolytes and the trace mineral base.

---
http://articles.mercola.com/sites/articles/archive/2000/10/01/mercury-autism-part-one.aspx

Mark said...

[another bit from mercola, the interest here is hardly his product it is the interesting summary list of ingredients...]

In Search of a Magic Bullet in Weight Loss?
http://products.mercola.com/biothin/

Like it or not, there really is no Magic Bullet or panacea that will instantly erase weight issues in one fell swoop.

One of the most important steps for effective weight management is to choose foods that were designed for your specific genetics and unique biochemistry. I have found that Nutritional Typing (NT) is a very effective strategy to achieve this. It will normalize your weight based on your personal metabolism and genetic makeup, among other factors.
weight loss

Sorry! No magic bullets available at this time. But there is still hope. Read on…

Another crucial element is to get 30-60 minutes of appropriate exercise each and every day. Find something you like to do — and commit to doing it religiously. Get an accountability partner to help you be consistent.

Now that spring is here, something as simple as a walk or bike ride in your neighborhood will get you started toward better health, just in time for summer.

Those are the two most critical actions to take to help with weight loss.

Then, if you need an additional boost for your weight loss efforts — and a jump start to success you will want to consider a natural adjunct filled with beneficial herbs.

BioTHIN™is an all-new and all-natural supplement that I formulated to help better address your weight loss concerns*. And I can assure you that this help harmonizes with the way you were designed to lose weight — and with overall healthy living.

BioTHIN™ is formulated to give you the edge you seek, to make a long-term difference in your weight loss and overall health*.

What’s more, it will put you back in the driver’s seat of your health.

Go First to Nature’s Storehouse!

Your body is part of the natural world.

That’s why I used only natural products in BioTHIN™.

There’s a lot of ongoing research on the weight loss benefits of various natural food products that shows great promise. Foods that, incidentally, have been used throughout history for healthful rejuvenation.

That’s why BioTHIN™ contains botanicals traditionally used to support normal weight loss and weight maintenance functions*.



Secrets of the Asian Diet - Fucoxanthin

Let’s go first to fucoxanthin – one of the most exciting things to hit the weight loss market in a long time.

As you may know, I have not historically been a fan of weight loss supplements –that is, until fucoxanthin came out.
weight loss

Fucoxanthin, just one of the key ingredients in BioTHIN™.

Fucoxanthin is a natural carotenoid (natural pigments found primarily in plants and algae).

Fucoxanthin exists naturally in brown seaweed — a type of kelp — that gives brown seaweed its characteristic brown color. Preliminary animal research performed in Russia and Japan suggests that fucoxanthin may help burn fat*.

Also, here’s a huge plus for you and others searching for an effective yet natural option that doesn’t disrupt your activities and sleep.

Fucoxanthin revs up your metabolism without stimulating your central nervous system*. Which means you can go about your normal lifestyle with total peace of mind, fulfilling all your normal commitments.

Now to mention another advantage…Evidence is emerging showing that the fucoxanthin component is a powerful antioxidant that can protect your cells from free radical damage*. It also may support your:

* Cardiovascular health*
* Inflammatory response*
* Optimal cholesterol and triglyceride levels*
* Optimal blood pressure levels*
* Healthy liver function*

So, for natural weight loss, along with eating according to your NT plus exercising, I urge you to consider BioTHIN™ with fucoxanthin to jumpstart your weight loss efforts*.

But wait! That’s just part of the story…

An Ancient Source with Modern Applications - Pomegranate

The pomegranate has been a staple of Asian diets since ancient times. They were mentioned in Egyptian papyrus scrolls dating back to 1550 BC. And in ancient Greek myths, the pomegranate represented life and regeneration.

Its herbal use dates back more than 3,000 years. Modern science is actively rediscovering its potential for a more healthful life.

Recent studies reveal a surprising host of benefits for eating pomegranate.

The pomegranate — an Asian staple, and a Greek symbol of life and regeneration.

Pomegranates contain powerful antioxidants that deal with free radicals in your system.* One study suggested that pomegranates showed three times the antioxidant activity of green tea or red wine*.

Other studies suggest that pomegranates contain bioflavonoids that help maintain healthy capillary walls*.

BioTHIN™ is further enhanced with pomegranate extract standardized to 40% punicosides. These are the most powerful antioxidants in pomegranate.

Research suggests other benefits from pomegranate:

* Contributes to tissue health*
* Supports heart health*
* Supports healthy blood lipid levels*
* Supports the immune system*
* Helps maintain proper oxidative balance in your body*

As if that’s not enough, BioTHIN™ includes another plant that’s just now becoming popular in weight management — though it has existed for a long time.

Weight Loss Miracle from African Bushmen - Hoodia

Which leads me to ask you — what’s the African wonder plant that can kill the appetite and stop cravings*?

Don’t know?

Ever heard of Hoodia Gordonii?
weight loss

Hoodia — source of a new weight loss miracle?

It’s a bitter-tasting cactus-like succulent plant from the Kalahari Desert in Africa. Nomadic San Bushmen tribesmen have eaten Hoodia for untold generations to stave off hunger while on long hunts through the harsh and scorching desert.

This astonishing but rather ugly plant contains a molecule that tricks your brain into thinking your stomach is full. When your brain thinks you’re full, you will eat less – without ‘torturing’ yourself!

Thirty years of research and testing led to the discovery of the previously unknown molecule now called P57.

Here’s how scientists think it works. The hypothalamus in your brain senses glucose levels and triggers a signal to your body to quit eating. Researchers at Brown University believe P57 is about 1,000 times as active as glucose, so it evidently sends its ‘stop eating’ message even when you have not eaten.

When crews from BBC and “60 Minutes” traveled to South Africa to investigate this story, they naturally tried Hoodia for themselves. The BBC reporter and crews said they experienced no hunger for 36 hours after eating Hoodia. “60 Minutes” correspondent Leslie Stahl reported that she wasn’t hungry all day.

[Less sugared dark chocolate is something close to what the Maya did to reduce hunger in their warriors and merchant travellers. It really can make you lose your sense of hunger to eat a lot of dark chocolate just like the Maya did, I have found through some delicious experiments on myself...]

What’s more, when scientists fed Hoodia to rats (a species that will eat anything), the rats stopped eating.

Yet Hoodia has no known side effects based on studies done to date.

I’m sure you’ll agree that Hoodia’s popularity will continue to grow as word gets out that it is a potent natural weight loss aid*. And I’m sure you’ll be glad we’ve added it to BioTHIN™!

But be aware! As popularity grows, the unscrupulous come on strong. Various scams are already being discovered with Hoodia. Presumably due to the high demand and price, some “Hoodia” supplements have even been discovered to be missing the Hoodia!

I wanted to protect you to be sure you were getting the authentic plant. So I got verification from the supplier attesting to it potency. The Hoodia in BioTHIN™ is sourced from South Africa and conforms to all standard tests that confirm its efficacy.

You are assuredly getting high-quality Hoodia. But this isn’t even all you get in this product…

Four More Natural Ingredients - Ginger Root, Cayenne, Garcinia Cambogia and Apple Cider Vinegar

Four other outstanding ingredients known for their weight loss impact and their contribution to your overall health are included in every serving of BioTHIN™.

*
weight loss

It may not look like much, but ginger has been treasured for centuries for its life-enhancing properties.
Ginger Root. Sought after for more than 5,000 years by the ancients of China and India for its health-promoting properties. Highly in demand by spice traders. Today, it is still a component of a full 50 percent of traditional herbal remedies.

Research suggests that it has the ability to help offset the lipid elevating effects of a high-fat diet*.
o Exhibit anti-oxidant effects on your body with its 12 different anti-oxidants.*
o Support optimal cell division process*
o Support cardiovascular health*
o Help control inflammatory response*
o Support digestive system health*
*
weight loss

Cayenne’s spiciness factor may heat up your health*…
Cayenne. Prized for thousands of years for its power to promote health. Cayenne, also known as capsicum, is one of many historically-valued herbs being studied today for its health benefits

Scientists believe that cayenne may act as a healthful catalyst when combined with other herbs* – a reason I included it in BioTHIN™’s formula.

Some animal and human studies also suggest that cayenne may help increase your body’s heat for a short time – causing you to burn more calories*. Additionally, research is ongoing about whether cayenne can help regulate blood sugar and break down carbohydrates after a meal*.

Cayenne contains vitamins A and C, has complete B complex, and is rich in calcium and potassium – offering you great nutritional value too.*

What else might both ginger and cayenne do for you? They’re reported to:
o Support cardiovascular health*
o Support digestive health*
o Help regulate normal detoxification*
o Help regulate inflammatory response*
o Provid energy*
* Garcinia Cambogia (standardized to 50% HCA). (standardized to 50% HCA). Garcinia is a small fruit resembling a pumpkin. It has a long and popular history in India as a condiment, and the dried rind is used as a flavoring in many dishes.

Preliminary research suggests that its biologically active compound, hydroxycitric acid (HCA), can inhibit the body’s ability to store lipids and fatty acids*.

This natural extract may also inhibit conversion of excess calories to body fat*. And it may suppress appetite by signaling your brain that enough food has been eaten, possibly through an increase in serotonin*.
* Apple Cider Vinegar. Apple cider vinegar (ACV) has been used for centuries as an energizing tonic and elixir.

ACV is a completely natural product resulting from a two-step fermentation process of apples, from which it retains all the nutritional benefits of the apples plus gaining the extra acids and enzymes from fermentation.

There are four suggested ways ACV may help you lose weight:
o May Increase Satiety*

The same hormonal reflex that sends a “full” message from your digestive system to your brain (discussed when talking about Hoodia earlier) is also triggered by ACV*.

Satiety means feeling full. Scientists think that satiety occurs more quickly with acetic acid* (the ‘sour’ part of ACV).

A preliminary Swedish study suggested that higher intake of ACV before meals was associated with significantly lower blood sugar and insulin responses and an increased satiety score*.
o May Suppress Appetite*

Pectin, the water-soluble fiber in apples and ACV, may absorb water and make your stomach feel a little full before beginning your meal*.
o May Increase Metabolic Rate*

ACV may help your digestion of protein, which is the building block of growth hormone*. Higher protein levels can mean more growth hormone, which may increase metabolism during your resting times *.

ACV may also improve your production of insulin*.
o May Improve Digestion*.

Improving your digestion means fats stay in your digestive tract for a shorter time, with less absorption of those fats into your system.

A number of other health benefits you might get from ACV are:
+ Helps support healthy bone structure through minerals (calcium, magnesium, silicone, plus a number of vitamins).*
+ Maintain healthy lipid levels.*
+ Maintain healthy heart and circulatory system.*
+ Control optimal inflammatory response.*
+ Aids in normal detoxification of your body.*
The biggest drawback to ACV is the taste and smell. We solved that problem for you by adding it to our all-natural weight-loss formula, BioTHIN™.

Now you can benefit from the harmony of these seven high-quality weight-loss-promoting plants and herbs in our easy-to-use and convenient formulation of BioTHIN™. They are living foods, just as nature intended!

See for yourself how our proprietary blend of powerful herbs, vitamins and minerals may be more beneficial to you than a single herb product could be.

Naturally, life experience tells you that there is no Magic Bullet. You will get your best weight loss results from the combination of:

* Eating healthy foods according to your Nutritional Type.
* Getting 30-60 minutes of exercise each day.
* Using bioTHIN™.

Using these three actions has the potential to improve your health far more than anything you’ve done in the past — and allow you to finally take charge of your own health.

---
http://products.mercola.com/biothin/

Mark said...

Tiny Capers Pack Big Disease-fighting Punch

ScienceDaily (Oct. 25, 2007) — Capers, used in such culinary delights as chicken piccata and smoked salmon, may be small.

See also:
Health & Medicine

* Lung Cancer
* Cholesterol
* Heart Disease

Plants & Animals

* Food
* Agriculture and Food
* Botany

Reference

* Mediterranean diet
* Meat analogue
* Saturated fat
* South Beach diet

But they are an unexpectedly big source of natural antioxidants that show promise for fighting cancer and heart disease when added to meals, particularly meats, researchers in Italy are reporting.

The flower buds of a small bush, capers have been used for centuries in Mediterranean cuisine, where they provide a salty tang and decorative flair to a variety of meats, salads, pastas and other foods.

In the new study, Maria A. Livrea and colleagues note that other foods in the so-called Mediterranean diet have gotten plenty of attention for their health benefits. Capers, however, have been largely overlooked.

Their laboratory study involved adding caper extracts to grilled ground-turkey, and analyzing byproducts formed during simulated digestion. The scientists found that caper-extract helped prevent the formation of certain byproducts of digested meat that have been linked by others to an increased risk of cancer and heart disease. That beneficial effect occurred even with the small amounts of caper typically used to flavor food.

"Caper may have beneficial health effects, especially for people whose meals are rich in fats and red meats," the study concluded.

The article, "Bioactive Components of Caper (Capparis spinosa L.) from Sicily and Antioxidant Effects in a Red Meat Simulated Gastric Digestion." is published in the Oct. 17 issue of ACS' Journal of Agricultural and Food Chemistry.

---
http://www.sciencedaily.com/releases/2007/10/071022212740.htm

Mark said...

Interventional Neuroradiologists Treat Brain Strokes with New Kind of Stent

April 1, 2006 — A new "wingspan" stent helps restore blood flow for patients with intracranial atherosclerotic disease, or ICAD.

Surgeons insert the stent up the leg arteries, guide it to the brain, then let its wire mesh expand, propping open a clogged blood vessel. The new stent, designed for the fragile, curvy arteries in the brain, replaces stiffer stents used in heart and neck vessels.

See also:
Health & Medicine

* Heart Disease
* Hypertension

Mind & Brain

* Stroke
* Brain Injury

Matter & Energy

* Nature of Water
* Medical Technology

Reference

* Ischaemic heart disease
* Blood pressure
* Multi-infarct dementia
* Stroke

When a stroke hits, it hits the brain hard -- many times causing paralysis, speech problems, or even death. Now, doctors have a new weapon against this deadly brain attacker.

John Dietz is happy to be back on his feet after a surprise stroke left him almost speechless. "I have trouble getting the words out. I know the words in my brain, but I can't get them out."

The artery in John's brain that caused the stroke was almost completely blocked. Now, to save his life a new tiny, flexible stent to open clogged arteries and prevent another stroke from happening is in his brain.

Traditional stiff stents are used to treat blockages in the heart and neck. The new wingspan stent, however, is designed for the fragile, curvy arteries in the brain.

Abraham Obuchowski, an interventional neuroradiologist at the University of Maryland Medical Center in Baltimore, says, "The stent is more flexible so it can make the turns to get up into the brain."

Neuroradiologists guide the wire-mesh stent with a catheter up the artery in the leg leading to the brain. Then a protective covering is removed and the self-expanding stent props open the clogged artery. "You can actually take it and squeeze it and crush it, and it will pop back into position. So that's what's unique about this stent," Dr. Obuchowski says.

John is hopeful this unique device will help him have a stroke-free future.

The new wingspan stent system is designed for patients with intracranial atherosclerotic disease, or ICAD. Until now, the only treatment option for these patients was medication therapy like aspirin or using a heart stent in the brain.

BACKGROUND: A new medical device can open clogged arteries in the brain, helping prevent strokes. Called the Wingspan Stent System, it is specifically designed to treat blockages caused by intracranial athlerosclerotic disease, a condition that causes strokes. While it won't address risk factors such as high blood pressure or high cholesterol, the device will significantly decrease a patient's risk of stroke.

WHAT ARE STENTS? A stent is essentially a small piece of metal "scaffolding" that pushes arterial plaque to the side and provides a framework to keep the blood vessel open so that the blood can flow freely through it. Stents have been used for many years to clear blockages in the arteries of the heart and neck. But arteries in the brain are fragile, with many more curves, so it is much harder to get the stent to the blockage site. Steel stents can injure those vessels. The Wingspan stent is made of an alloy of nickel and titanium, which puts less pressure on the blood vessel when it expands.

HOW IT WORKS: Neuroradiologists insert a catheter into an artery in the upper leg. Using digital X-rays for image guidance, they then navigate the catheter through the blood vessels to the site of the blockage in the brain. They then slowly inflate an angioplasty balloon to push away the plaque and put the stent in place to hold the vessel open.

ABOUT STROKES: The brain is made up of living cells that require a constant supply of nutrient- and oxygen-rich blood. Blockage or rupture of the blood vessels supply parts of the brain cause most strokes. A stroke occurs when brain tissue is deprived of blood and brain cells die from the lack of oxygen. Depending on which area of the brain is affected, a stroke can cause vision problems, speech problems, disability, even death. Traditionally, treatment for stroke-causing diseases involves blood-thinning drugs to prevent clots, but for patients with severe blockage, this may not be sufficient. Some temporary blockages only last minutes or hours, leading to mini-strokes. Mini-strokes are a sign of a serious problem and can lead to a permanent stroke if left untreated.

ABOUT BLOOD FLOW: The heart pumps blood through the arteries, capillaries and veins to provide oxygen and nutrients to every cell of the body, and also carries away waste products from those cells. The liquid portion of the blood is called plasma. It distributes various nutrients and chemicals throughout the body, diffusing into the tissues and cells. In general, they diffuse from areas of high concentration to areas of low concentration. Waste flows in the opposite direction and are removed in the kidneys or the lungs. Blood pressure pushes fluid out of blood vessels. This is balanced by something called oncotic pressure, which keeps fluid inside the blood vessels so that the body maintains a constant volume of blood.

---
http://www.sciencedaily.com/videos/2006/0407-stroke_stopper.htm

Mark said...

The good news in our DNA: Defects you can fix with vitamins and minerals

General Science / Biology

As the cost of sequencing a single human genome drops rapidly, with one company predicting a price of $100 per person in five years, soon the only reason not to look at your "personal genome" will be fear of what bad news lies in your genes.

University of California, Berkeley, scientists, however, have found a welcome reason to delve into your genetic heritage: to find the slight genetic flaws that can be fixed with remedies as simple as vitamin or mineral supplements.

"I'm looking for the good news in the human genome," said Jasper Rine, UC Berkeley professor of molecular and cell biology.

"Headlines for the last 20 years have really been about the triumph of biomedical research in finding disease genes, which is biologically interesting, genetically important and frightening to people who get this information," Rine said. "I became obsessed with trying to decide if there is some other class of information that will make people want to look at their genome sequence."

What Rine and colleagues found and report this week in the online early edition of the journal Proceedings of the National Academy of Sciences (PNAS) is that there are many genetic differences that make people's enzymes less efficient than normal, and that simple supplementation with vitamins can often restore some of these deficient enzymes to full working order.

First author Nicholas Marini, a UC Berkeley research scientist, noted that physicians prescribe vitamins to "cure" many rare and potentially fatal metabolic defects caused by mutations in critical enzymes. But those affected by these metabolic diseases are people with two bad copies, or alleles, of an essential enzyme. Many others may be walking around with only one bad gene, or two copies of slightly defective genes, throwing their enzyme levels off slightly and causing subtle effects that also could be eliminated with vitamin supplements.

"Our studies have convinced us that there is a lot of variation in the population in these enzymes, and a lot of it affects function, and a lot of it is responsive to vitamins," Marini said. "I wouldn't be surprised if everybody is going to require a different optimal dose of vitamins based on their genetic makeup, based upon the kind of variance they are harboring in vitamin-dependent enzymes."

Though this initial study tested the function of human gene variants by transplanting them into yeast cells, where the function of the variants can be accurately assessed, Rine and Marini are confident the results will hold up in humans. Their research, partially supported by the Defense Advanced Research Projects Agency (DARPA) and the U.S. Army, may enable them to employ U.S. soldiers to test the theory that vitamin supplementation can tune up defective enzymes.

"Our soldiers, like top athletes, operate under extreme conditions that may well be limited by their physiology," Rine said. "We're now working with the defense department to identify variants of enzymes that are remediable, and ultimately hope to identify troops that have these variants and test whether performance can be enhanced by appropriate supplementation."

In the PNAS paper, Rine, Marini and their colleagues report on their initial analysis of variants of a human enzyme called methylenetetrahydrofolate reductase, or MTHFR. The enzyme, which requires the B vitamin folate to work properly, plays a key role in synthesizing molecules that go into the nucleotide building blocks of DNA. Some cancer drugs, such as methotrexate, target MTHFR to shut down DNA synthesis and prevent tumor growth.

Using DNA samples from 564 individuals of many races and ethnicities, colleagues at Applied Biosystems of Foster City, Calif., sequenced for each person the two alleles that code for the MTHFR enzyme. Consistent with earlier studies, they found three common variants of the enzyme, but also 11 uncommon variants, each of the latter accounting for less than one percent of the sample.

They then synthesized the gene for each variant of the enzyme, and Marini, Rine and their UC Berkeley colleagues inserted these genes into separate yeast cells in order to judge the activity of each variant. Yeast use many of the same enzymes and cofactor vitamins and minerals as humans and are an excellent model for human metabolism, Rine said.

The researchers found that four different mutations affected the functioning of the human enzyme in yeast. One of these mutations is well known: Nearly 30 percent of the population has one copy, and nine percent has two copies.

The researchers were able to supplement the diet of the cultured yeast with folate, however, and restore full functionality to the most common variant, and to all but one of the less common variants.

Since this experiment, the researchers have found 30 other variants of the MTHFR enzyme and tested about 15 of them, "and more than half interfere with the function of the enzyme, producing a hundred-fold range of enzyme activity. The majority of these can be either partially or completely restored to normal activity by adding more folate. And that is a surprise," Rine said.

Most scientists think that harmful mutations are disfavored by evolution, but Rine pointed out that this applies only to mutations that affect reproductive fitness. Mutations that affect our health in later years are not efficiently removed by evolution and may remain in our genome forever.

The health effects of tuning up this enzyme in humans are unclear, he said, but folate is already known to protect against birth defects and seems to protect against heart disease and cancer. At least one defect in the MTHFR enzyme produces elevated levels in the blood of the metabolite homocysteine, which is linked to an increased risk of heart disease and stroke, conditions that typically affect people in their post-reproductive years.

"In those people, supplementation of folate in the diet can reduce levels of that metabolite and reduce disease risk," Marini said.

Marini and Rine estimate that the average person has five rare mutant enzymes, and perhaps other not-so-rare variants, that could be improved with vitamin or mineral supplements.

"There are over 600 human enzymes that use vitamins or minerals as cofactors, and this study reports just what we found by studying one of them," Rine said. "What this means is that, even if the odds of an individual having a defect in one gene is low, with 600 genes, we are all likely to have some mutations that limit one or more of our enzymes."

The subtle effects of variation in enzyme activity may well account for conflicting results of some clinical trials, including the confusing data on the effect of vitamin supplements, he noted. In the future, the enzyme profile of research subjects will have to be taken into account in analyzing the outcome of clinical trials.

If one considers not just vitamin-dependent enzymes but all the 30,000 human proteins in the genome, "every individual would harbor approximately 250 deleterious substitutions considering only the low-frequency variants. These numbers suggest that the aggregate incidence of low-frequency variants could have a significant physiological impact," the researchers wrote in their paper.

All the more reason to poke around in one's genome, Rine said.

"If you don't give people a reason to become interested in their genome and to become comfortable with their personal genomic information, then the benefits of much of the biomedical research, which is indexed to particular genetic states, won't be embraced in a time frame that most people can benefit from," Rine said. "So, my motivation is partly scientific, partly an education project and, in some ways, a partly political project."

Marini and Rine credit Bruce Ames, a UC Berkeley professor emeritus of molecular and cell biology now on the research staff at Children's Hospital Oakland Research Institute, with the research that motivated them to look at enzyme variation. Ames found in the 1970s that many bacteria that could not produce a specific amino acid could do so if given more vitamin B6, and in recent years he has continued exploring the link between micronutrients and health.

"Looked at in one way, Bruce found that you can cure a genetic disease in bacteria by treating it with vitamins," Rine said. Because the human genome contains about 6 billion DNA base pairs, each one subject to mutation, there could be between 3 and 6 million DNA sequence differences between any two people. Given those numbers, he reasoned that, as in bacteria, "there should be people who are genetically different in terms of the amount of vitamin needed for optimal performance of their enzymes."

This touches on what Rine considers one of the key biomedical questions today. "Now that we have the complete genome sequences of all the common model organisms, including humans, it's obvious that the defining challenge of biology in the 21st century is not what the genes are, but what the variation in the genes does," he said.

Rine, Marini and their colleagues are continuing to study variation in the human MTHFR gene as well as other folate utilizing enzymes, particularly with respect to how defects in these enzymes may lead to birth defects. Rine also is taking advantage of the 1,500 students in his Biology 1A lab course to investigate variants of a second vitamin B6-dependent enzyme, cystathionine beta-synthase.

He also is investigating how enzyme cofactors like vitamins and minerals fix defective enzymes. He suspects that supplements work by acting as chaperones to stabilize the proper folding of the enzyme, which is critical to its catalytic activity. "That is a new principle that may be applicable to drug design," Rine said.

Source: University of California - Berkeley

---
http://www.physorg.com/news131645933.html

Mark said...

Dementia patient makes 'amazing' progress after using infra-red helmet

By David Derbyshire
Last updated at 2:26 AM on 15th July 2008

Two months ago Clem Fennell was fading fast.

The victim of an aggressive type of dementia, the 57-year-old businessmen was unable to answer the phone, order a meal or string more than a couple of words together.

In desperation, his family agreed to try a revolutionary new treatment - a bizarre-looking, experimental helmet devised by a British GP that bathes the brain in infra-red light twice a day.

To their astonishment, Mr Fennel began to make an astonishing recovery in just three weeks.

Dr Gordon Dougal

Dr Gordon Dougal, a GP from County Durham, treated dementia patient Clem Fennell with his infra-red device

"My husband, Clem, was fading away. It is as if he is back" said his wife Vickey Fennell, 55. "His personality has started to show again. We are absolutely thrilled."

While the helmet has yet to be proven in clinical trials, the family say the effects of the 10 minute sessions are incredible.

Mr Fennell can now hold conversations and go shopping unaccompanied.

The treatment is the brainchild of Dr Gordon Dougal, a County Durham GP. He believes the device could eventually help thousands of dementia patients.

"Potentially, this is hugely significant," said Dr Dougal, who is based in Easington, County Durham and is a director of Virulite, a medical research company.

Developed with Sunderland University, the helmet has 700 LED lights that penetrate the skull.

They are thought to be the right wavelength to stimulate the growth of brain cells, slowing down the decline in memory and brain function and reversing symptoms of dementia.

Clem Fennell - the head of a family engineering firm in Cincinnati, Ohio - travelled to the UK after neurologists told him nothing could stop the decline of his dementia.

The family's friends had seen a report about the helmet on CBS.

"Honestly I can tell you that within ten days, the deterioration was stopped, then we started to see improvements," said Mrs Fennell, from North Kentucky. "He started to respond to people more quickly when they talked to him."

Three weeks later, the father of two is still making gradual improvements.

His daughter, 22-year-old Maggie said: "When we go to the restaurant we usually have to order his meals for him, now he can order for himself."

"Now we are okay about letting him go to the bank or the post office but he would not have been able to do that three weeks ago.
Clem Fennell

Mr Fennell could hardly string two words together. But since using the infra-red helmet, he can hold a conversation.

"Dr Dougal has been a godsend to our family. There was nothing anyone could do to help Clem until now."

It is too soon to say whether Dr Dougal's invention could help other sufferers. The symptoms of Alzheimer's disease and dementia can vary from day to day - and relapses are not unusual. And not all patients may benefit from the treatment.

Dr Dougal stressed that a full, clinically controlled trial would be needed before his anti-dementia helmet could be licensed for public use. A trial of 100 patients is expected to start later this year.

"I made it clear to the Fennells that I didn't know for a fact whether it would work or not, but the results are good," said Dr Dougal.

"He was monosyllabic when I first saw him, but if I ring up now he will answer the phone. He didn't have the verbal skills to do that three weeks ago."

The Fennells have been told they can take the prototype helmet back to the US with them so they can continue the treatment at home.

Commercial versions of the helmet will include 700 LEDs and cost around £10,000.

The Alzheimer’s Society said: "’A treatment that reverses the effects of dementia rather than just temporarily halting its symptoms could change the lives of the hundreds of thousands of people who live with this devastating condition.

‘Non-thermal near infra-red treatment for people with dementia is a potentially interesting technique. We look forward to further research to determine whether it could help improve cognition in humans. Only then can we begin to investigate whether near infra-red could benefit people with dementia.’

One in three people will end their lives with a form of dementia. Around 700,000 suffer from dementia - with more than half having Alzheimer's disease.

---
http://www.dailymail.co.uk/health/article-1034936/Dementia-patient-makes-amazing-progress-using-infrared-helmet.html?ITO=1490

Mark said...

Mad as a Hatter -- How to Avoid Toxic Metals and Clear Them From the Body (PDF) [13 pages, Weston Price Foundation]
http://mercola.fileburst.com/PDF/ToxicMetals.pdf

Mark said...

[Another bioelectrical self-healing cure for arthritis is the Vibe Machine of Gene Koonze, which he described in his video.]


Frankincense 'can ease arthritis'
Frankincense

Frankincense is used in aromatherapy and religious ceremonies

A herb known as "Indian Frankincense" can reduce the symptoms of arthritis, US researchers have suggested.

Extracts from Boswellia serrata, a similar species to the variety famous for its role in the Christian nativity, were tested on dozens of patients.

Those who received it reported better movement and less pain and stiffness.

The herb has been used for thousands of years in Indian Ayurvedic medicine, reports the journal Arthritis Research and Therapy.


Certainly osteoarthritis is in need of new safe analgesics, although many effective therapies that reduce pain such as muscle strengthening exercises, shock-absorbing footwear and weight loss have very few bad side effects
Professor Philip Monaghan
Arthritis Research Campaign

Osteoarthritis is the most common form of the condition, and normally affects the weight bearing joints such as hands, wrists, feet and spine. [Milk drinking countries are the ones with the worst arthritis and osteoarthritis.]

Current treatments carry a great many adverse effects, and scientists have been hunting for an alternative.

The investigation into the properties of Boswellia serrata was led by Dr Siba Raychaudhuri at the University of California, Davis.

Eventually they tested an extract of the plant enriched with the chemical - AKBA - thought to be its active ingredient.

Some of the 70 patients with severe arthritis in their knees recruited into the trial were given a low-dose capsule, some a higher dose capsule, and the remainder were given a dummy pill with no active ingredients.

In as little as seven days, patients taking the frankincense drug reported improvements in their pain and stiffness levels compared with the placebo group, and these continued until the 90-day mark, when the study ended.

Alternative therapies

Tests of the fluid within affected joints also revealed falls in levels of enzymes linked to the condition.

Dr Raychaudhuri said: "We have shown that B. serrata enriched with AKBA can be an effective treatment for osteoarthritis of the knee."

However, UK experts urged caution. Professor Philip Conaghan, from Leeds University, and a spokesman for the Arthritis Research Campaign, said: "Certainly osteoarthritis is in need of new safe analgesics, although many effective therapies that reduce pain such as muscle strengthening exercises, shock-absorbing footwear and weight loss have very few bad side-effects.

[Qigong may help as well.]


"This report on treating knee pain with a chemical derivative of B. serrata is interesting but the patient numbers are small, there were some problems with the reported trial design and we need more information on its medium to long-term safety."

---
http://news.bbc.co.uk/2/hi/health/7535733.stm

Mark said...

[This may connect with the red wine chemical described above in healthy longevity. There was another story recently about a Muslim woman who drank a bit of olive oil everyday and ate a local Muslim salad vegetable regularly. No one knows her real age, though it is likely over 120 years of age. The Israeli identification card notes gave her the official year of birth as 1888. She still looked good for her age and moves quickly, though is very hard of hearing.]

Alcohol 'cuts risk of arthritis'
Rheumatoid arthritis
Rheumatoid arthritis can be extremely debilitating

A regular tipple cuts the risk [i.e., is correlated, though they don't know the cause yet] of developing rheumatoid arthritis by up to half, Swedish research suggests.

The Karolinska Institute assessed 2,750 people in two studies, Annals of the Rheumatic Diseases reports.

The risk was up to 50% lower for those who drank the equivalent of five glasses of wine a week compared with those who drank the least, they found.

However, arthritis experts warned that drinking too much alcohol increased the risk of a range of health problems.

Rheumatoid arthritis - an auto-immune disease caused by a malfunctioning immune system - is a condition which results in tender, stiff and swollen joints. It affects 400,000 people in the UK.

The two separate studies assessed environmental and genetic risk factors for rheumatoid arthritis.

Participants were quizzed about their lifestyle, including how much they smoked and drank, while blood samples were taken to check for genetic risk factors.

Smoking highlighted

Researcher Dr Henrik Kallberg stressed the most important finding of the study was that smoking was a very significant risk factor for rheumatoid arthritis, reinforcing findings from previous studies.

However, he added: "In addition, it is important to know that moderate alcohol consumption is not deleterious and may in some contexts be beneficial concerning risk for future onset of rheumatoid arthritis."

There are known to be links between moderate alcohol consumption and a reduced risk of other inflammatory processes, such as cardiovascular disease. However, the reason for this is still unclear.

Professor Robert Moots, from the Arthritis Research Campaign, said it was possible that drinking alcohol may have a protective effect against rheumatoid arthritis.

But he said the study was not conclusive and any protective effect was not properly understood.

He said: "There is no doubt that drinking too much is very bad for our health in many ways and these risks by far outweigh any potential benefit for reducing the risk of rheumatoid arthritis, which this study points to, without being conclusive.

"We must also remember that drinking alcohol in excess can be especially dangerous in patients taking some anti-rheumatoid drugs that may cause liver damage.

"There are many modifiable lifestyle risk factors for developing rheumatoid arthritis and, as this study also points out, smoking is by far the greatest."

A spokesman for Arthritis Care said: "It's too early to say what these findings may mean, so people with rheumatoid arthritis should continue to work in partnership with their health professionals to address their specific health needs."

---
http://news.bbc.co.uk/2/hi/health/7435002.stm

Another issue? It might be the slightly acidic 'wash' of alcohol helps to clean out biochemical deposits regularly?

Mark said...

A daily dose of garlic can save your life by cutting blood pressure, say researchers

By Daily Mail Reporter
Last updated at 8:56 AM on 01st August 2008

Natural alternative: A daily garlic supplement in powder form can significantly lower blood pressure

Garlic may lower blood pressure just as effectively as drugs, according to researchers.

Scientists looked at 11 international studies in which patients were given a daily garlic supplement in powdered form for between three and five months.

They found significant blood pressure falls among participants - with the greatest drops among those who had higher blood pressure readings to begin with.

In some cases, the effects were similar to those achieved with common anti-blood pressure drugs, such as beta blockers and ACE inhibitors, said Dr Karin Ried, of Adelaide University in South Australia.

More than 16million Britons have high blood pressure and many more are thought to suffer from it without knowing. If the condition is not treated, it can lead to heart attacks and strokes. Doctors recommend that sufferers lower their blood pressure by cutting their intake of salt, losing weight and getting fit.

Now the Australian research suggests that extra help is at hand in readily available over the counter garlic supplements.

Dr Ried and her team, writing for the scientific journal BMC Cardiovascular Disorders, said the 600mg to 900mg dosage used in the studies was equivalent to 3.6mg to 5.4mg of garlic's active ingredient, allicin.

A fresh clove of garlic contains 5mg to 9mg of allicin.

More research was needed to determine whether garlic supplements might have a long-term effect on heart disease risk, the researchers added.

Potent stuff: The active ingredient allicin lowers blood pressure and is also what gives a clove of garlic its pungent smell

---
http://www.dailymail.co.uk/health/article-1040367/A-daily-dose-garlic-save-life-cutting-blood-pressure-say-researchers.html

Mark said...

Daily pill that halts Alzheimer's is hailed as 'biggest breakthrough against disease for 100 years'

By Jenny Hope
Last updated at 11:57 PM on 29th July 2008

Alzheimer's

Breakthrough: The new drug reverses symptoms in 81% of patients

A new drug halts the devastating progress of Alzheimer’s disease, say British scientists.

It is said to be more than twice as effective as current treatments.

A daily capsule of rember, as the drug is known, stops Alzheimer’s disease progressing by as much as 81 per cent, according to trial results.

Patients with the brain disorder had no significant decline in their mental function over a 19-month period.

‘We appear to be bringing the worst affected parts of the brain functionally back to life,’ said Dr Claude Wischik, who led the research.

It is the first time medication has been developed to target the ‘tangles’ in the brain that destroy nerve cells, leading to deteriorating memory.

The drug helps to disrupt this process, preventing the formation of new tangles and loosening those already created.

Last night the findings were hailed as the biggest breakthrough in the battle against Alzheimer’s since 1907.

Eventually the drug could be used to stop the disease in its early stages before symptoms have even appeared, it is hoped.

It could be available to patients within four years although, in the wake of the NHS ban on the £2.50-a-day drug Aricept, there are concerns over whether it would be funded on the [British] Health Service.

The trial was carried out by a team at the University of Aberdeen, led by Professor Wischik, who 20 years ago discovered the ‘tau protein’ which makes up the tangles.

‘This is an unprecedented result in the treatment of Alzheimer’s disease,’ he said.

‘We have demonstrated for the first time that it may be possible to arrest progression of the disease by targeting the tangles that are highly correlated with the disease.

This is the most significant development in the treatment of the tangles since Alois Alzheimer discovered them in 1907.’

The research, presented at the International Conference on Alzheimer’s disease in Chicago, involved 321 people with mild and moderate Alzheimer’s disease in the UK and Singapore.

They were divided into four groups, three taking different doses of rember and a fourth group taking a placebo or dummy capsule.

After 50 weeks, those with both mild and moderate Alzheimer’s who were taking rember experienced 81 per cent less mental decline compared with those on the placebo. [How you measure 'mental decline'--across different people with different personalities and different starting points--is a difficult question?]

Those taking rember did not experience any significant decline in their mental function over 19 months, while those on the placebo got worse.

The results suggest the drug is about two-and-a-half times more effective than existing drugs called cholinesterase inhibitors.

Images of the brain showed rember had its biggest effect in the parts linked to memory, where the density of tau tangles is greatest, with better blood flow to these areas.

The drug works by dissolving the tangle of tau fibres which releases waste products that kill nerve cells, and by preventing the fibres from becoming tangled.

Consultant psychiatrist Dr Donald Mowat, who monitored the progress of patients, said they were more confident, better able to cope with daily life and not experiencing the level of mental decline they had expected.

[What about side effects?]

The trial was a Phase 2 study, which checks the safety and efficacy of the drug, but if a large-scale Phase 3 trial due next year repeats the findings, the drug could be available for prescribing by 2012. At the same time, the research team is investigating a way of diagnosing Alzheimer’s at its earliest stages when tau tangles are first being formed in the brain.

People may have these tangles in their 50s, long before symptoms develop, and the researchers hope the drug could be used as a preventive treatment.

Professor Wischik co-founded TauRx Therapeutics, which is developing the treatment.

Professor Stephen Logan, professor of neuroscience and TauRx board member, said: ‘This is a fantastic breakthrough and very exciting.

‘Patients have been doing well for 18 or 19 months. They are continuing to take the drug and will probably do so until there is no benefit or they start to decline.

‘It’s not reversing the disease process [in other words it's just a palliative], but appears to stabilise it. It could be on the market by 2012.’

Professor Logan said the team is working on scanning techniques to detect the early stages of tangles so the drug could be used as a preventive but this would take much longer to perfect.

He said the cost of the treatment is unknown but would need to be compared with the expense of caring for Alzheimer’s sufferers both in the community and in hospital.

Existing Alzheimer’s drugs costing £2.50 have been banned for NHS use in sufferers of ‘mild’ disease on grounds of cost.

Around 700,000 Britons have dementia, with the majority suffering Alzheimer’s [when a portion of Alz, at least in USA studies, is actually CDD/BSE/mad cow related, due to false diagnoses of CJD as "Alzheimers"], and the number is increasing as people live longer.

Professor Clive Ballard, head of research at the Alzheimer’s Society, said it is a major development.

But he warned there is a long way to go before the treatment will become available for patients.

He said: ‘It is the first realistic evidence that a new drug can improve cognition in people with Alzheimer’s.

‘However we are not there yet. Larger scale trials are now needed to confirm the safety of this drug and establish how far it could benefit the thousands of people living with this devastating disease.’

I feel more confident, more positive

Sandra Sutherland had been struggling to focus on her job in accounts for several years when she was diagnosed with Alzheimer’s.

The 61-year-old tested positive for the disease in 2005 as doctors investigated another medical condition.

Sandra Sutherland with husband Ian

Drug trial: Sandra Sutherland with husband Ian

She said: ‘When I was diagnosed I was absolutely gobsmacked. I tell everyone that I meet that I have Alzheimer’s and they can’t believe it.’

Mrs Sutherland, who lives with her husband and two sons in Aberdeen and enjoys crosswords and gardening, started a trial of rember two years ago and believes the medication has helped her.

She said: ‘Since I’ve been on the trial I feel more confident, more positive. I think my concentration has levelled off and not got any worse.’

Her husband Ian added: ‘Sandra still has days when she is not great

‘But there has been no decline in the mini-mental tests she has had to do as part of the trial, so it would appear the medication is working.’

Jimmy Hardie, 72, used to put sugar mistakenly in the fridge and suffered mood swings. He and his wife Dorothy, a 69-year-old former nurse, live in the coastal village of Boddam, south of Peterhead in Aberdeenshire.

The couple have two children and five grandchildren, who all live in the Buchan area.

Mr Hardie was diagnosed with Alzheimer’s disease three years ago, after he began to suffer ‘blank’ periods and could not remember what he was about to do. He started on the rember trial in 2006.

Mrs Hardie said she believes the treatment has helped her husband gain confidence. He runs a trout fishery, is an enthusiastic handyman and loves his shed.

‘Two years ago if Jimmy had gone to his shed, he may have forgotten what he was about to do,’ she said. ‘Now he is able to plan what he wants to do, go and get the tools that he needs and do the task. It is very encouraging.’

Mr Hardie, who worked at the nearby power station for 14 years, added: ‘I feel the treatment has helped me. Having a lot of friends and hobbies has also been a great help.’

---
http://www.dailymail.co.uk/health/article-1039677/Daily-pill-halts-Alzheimers-hailed-biggest-breakthrough-disease-100-years.html

Mark said...

Vitamin C 'breakthrough' in war on cancer

Published Date: 05 August 2008
By Lyndsay Moss

INJECTIONS of vitamin C could halve the growth of cancerous tumours, research suggested yesterday.

A study in the United States found that the vitamin could prove useful in treating cancers for which few other options currently exist.

The breakthrough, which comes following tests on mice, follows decades of research into the potential of vitamin C in tackling cancer.

However, experts warned that the benefits of the vitamin had yet to be demonstrated in human patients. [huh?]

For the latest study, researchers from the National Institutes of Health in Bethesda, Maryland, examined the effects of vitamin C on cells grown in laboratories. Two hours of exposure to the vitamin significantly cut the survival of ovarian, pancreatic and brain tumour (glioblastoma) cancer cells.

Similar results were seen when cancer-ridden mice were injected with vitamin C.

The therapy halved the growth of aggressive tumours, killing cancer cells while leaving healthy tissue unharmed.

It is thought the discovery could provide a new lifeline for patients with a poor prognosis and few other options.

Tackling cancer with vitamin C would also have the added advantage of being cheap compared with many of the very expensive cancer treatments.

Usually the body keeps a tight rein on high vitamin C levels in the blood. But the scientists found that the mechanism can be by-passed if the vitamin is injected straight into the blood instead of passing through the digestive system. When this is done it releases the powerful anti-cancer potential of the vitamin, according to the researchers writing in the journal Proceedings of the National Academy of Sciences.

The experiments showed that high levels of vitamin C in the blood generate hydrogen peroxide, which is lethal to tumours. The chemical forms in the spaces between cancer cells, damaging membranes, upsetting metabolism and scrambling the DNA of the tumour.

Even the growth of aggressive cancers was held back in the experiments. But healthy tissues appeared to resist the effects.

The use of high-dose vitamin C as an alternative cancer treatment has a long history dating back to the 1970s.

Patients have taken the vitamin both by mouth and intravenously, but with mixed results in scientific trials. For this reason, claims that vitamin C can treat cancer have been dismissed by conventional cancer experts. But the new investigation, led by Dr Qi Chen, may help to start changing attitudes towards this approach.

The scientists said: "Pharmacologic concentrations of ascorbate (the chemical name for vitamin C] decreased tumour volumes 41-53 per cent in diverse cancer types known for both their aggressive growth and limited treatment options."

Dr Alison Ross, science information officer at Cancer Research UK, said: "This is encouraging work but it's at a very early stage because it involves cells grown in the lab and mice."

---
http://news.scotsman.com/uk/Vitamin-C--39breakthrough39-in.4356412.jp

2.

Cancer hopes as Vitamin C injections kill mice tumours


Vitamin C that is injected rather than swallowed could provide a new lifeline for cancer patients with a poor prognosis and few treatment options, according to new research. [How much better to inject amygdalin/latrile....]

Scientists say the therapy halved the growth of aggressive tumours in mice, killing cancer cells while leaving healthy tissue unharmed.

Tackling cancer with vitamin C would also have the added advantage of being less expensive, the research claims.

The body usually keeps tight control of vitamin C levels in the blood.

However, a new US-based investigation, led by Dr Qi Chen from the National Institutes of Health in Maryland, Ohio, found that the mechanism can be by-passed if the vitamin is injected straight into the bloodstream instead of passing through the digestive system.

When this is done it releases the powerful anti-cancer potential of the vitamin.

Experiments showed that high levels of vitamin C in the blood generate hydrogen peroxide, which is lethal to tumours. The chemical forms in the spaces between cancer cells, damaging membranes, upsetting metabolism and scrambling DNA.

Even the growth of aggressive, hard-to-treat cancers was held back in the studies. But healthy tissues appeared to resist the effects.

The use of high-dose vitamin C as a complementary or alternative cancer treatment was first promoted in the 1970s. Patients have taken the vitamin both by mouth and intravenously. But despite some positive outcomes, there has been insufficient reliable evidence that the therapy works leading conventional cancer experts to dismiss claims that vitamin C can treat cancer.

Dr Chen's investigation involved testing the effects of vitamin C on laboratory cell lines and cancer-ridden mice.

Laboratory tests showed that two hours of exposure to the vitamin significantly reduced the survival of ovarian, pancreatic and brain tumour cancer cells.

Similar results were achieved when mice bearing the same kinds of tumours were injected with vitamin C.

Writing in the journal Proceedings of the National Academy of Sciences, the scientists said: "Pharmacologic concentrations of ascorbate decreased tumour volumes 41-53% in diverse cancer types known for both their aggressive growth and limited treatment options."

They said a "rapid and sustained increase" in hydrogen peroxide was detected in tumour fluids within 30 minutes of the treatment commencing.

An early stage patient study showed that similar therapeutic levels of vitamin C in the blood could be achieved when ascorbate was administered intravenously in humans.

The scientist added: "A regimen of daily pharmacologic ascorbate treatment significantly decreased growth rates of ovarian, pancreatic and glioblastoma tumours established in mice.

"Similar pharmacologic concentrations were readily achieved in humans given ascorbate intravenously. These data suggest that ascorbate as a prodrug may have benefits in cancers with poor prognosis and limited therapeutic options."

Dr Alison Ross, science information officer at Cancer Research UK, said: "This is encouraging work but it's at a very early stage because it involves cells grown in the lab and mice. Much more research is needed before we'll know whether vitamin C could be a viable cancer treatment in the future.

"There is currently no evidence from clinical trials in humans that injecting or consuming vitamin C is an effective way to treat cancer. Some research even suggests that high doses of antioxidants can make [deadly unproven (statistically) nuclear medicine for most cancers], treatment less effective, reducing the benefits of radiotherapy and chemotherapy."

Vitamin C supplements have been hailed since the 1970s as an aid for fighting colds, principally thanks to the US Nobel Prizewinning chemist Dr Linus Pauling, who championed it.

...

---
http://www.theherald.co.uk/news/news/display.var.2417480.0.Cancer_hopes_as_Vitamin_C_injections_kill_mice_tumours.php

Mark said...

Obviously I've never seen this, so I'm just posting it for future reference and pondering:

"Frenchman Antoine Priore (with French government underwriting) had developed an age regression machine (based on reverse phase conjugation) in the late 60s and early 70s that could reverse disease conditions in animals (and later humans) by reverse aging the cells of the body back to an earlier point in time, when the cells were free of the disease. If you were to subject an entire human body to this technology, the entire body would naturally move back in time to an earlier point of youth."

http://educate-yourself.org/cn/martinbormannphotostocompare02jul07.shtml

Mark said...

Lorenzo's Oil boy is dead at 30

Lorenzo Odone, whose parents' battle to save him from a rare nerve disorder was depicted in the 1992 film Lorenzo's Oil, has died from pneumonia aged 30.

Doctors had predicted he would not live beyond childhood when he was diagnosed with the incurable disease aged six.

But his parents found what seemed to be a cure made of acids from olive and rapeseed oils.

Lorenzo died at his home in the US state of Virginia on Friday - a day after his 30th birthday.

He was suffering from aspiration pneumonia, which was caused by food getting stuck in his lungs.

His father Augusto said: "He could not see or communicate, but he was still with us. He did not suffer... That's the important thing."

Preventative treatment

Lorenzo had Adrenoleukodystrophy (ALD), a genetic disease that progressively destroys the brains of young boys.

The disease leads to the build up of dangerous fatty acids - long-chain fatty acids - in the blood, and within a year children are paralysed, blind, and unable to speak. It is invariably fatal.

Lorenzo was given less than two years to live but his parents refused to accept the doctors' prognosis.

With no scientific training, they took on the medical establishment and set about finding a cure.

In 1986 it seemed they had succeeded with a combination of oils that effectively reduced the long-chain fatty acids in the blood.


Despite the fairytale ending in the film, the claims have always been controversial and children suffering from ALD continued to die, despite being treated with Lorenzo's oil.

However, a 10-year study showed that while the oil does not appear to work for people who are already ill, it does seem to prevent illness in those whose genes make them vulnerable to developing symptoms.

Augusto Odone said his son's ashes would be taken to New York and placed with those of his wife Michaela, who died in 2000.

He added that he was planning to move back to his native Italy and write a book about his son.

Actors Susan Sarandon and Nick Nolte played Augusto and Michaela in the 1992 film. Lorenzo was played by Zack O'Malley Greenburg.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/americas/7429221.stm

Published: 2008/05/31 14:18:45 GMT

Mark said...

Scientists Create Blood From Stem Cells

By Brandon Keim EmailAugust 19, 2008 | 11:36:04

Scientists have used embryonic stem cells to generate blood -- a feat that could eventually lead to endless supplies of type O-negative blood, a rare blood type prized by doctors for its versatility.

"We literally generated whole tubes in the lab, from scratch," said Robert Lanza, chief science officer at Advanced Cell Technologies.

People usually require blood transfusions that match their own blood type: A mismatch can be fatal. Type O-negative can be safely transferred into anyone, but is only possessed by about 7 percent of the population, leaving supplies perpetually short.

The new technique, devised by Lanza and colleagues at the Mayo Clinic and University of Illinois, is still preliminary. Its safety hasn't yet been proved in animals, much less humans.

But because blood cells are short-lived and cannot divide, there's reason to believe that stem cell-derived blood cells could pose fewer complications than other therapeutic stem cells, which can divide unpredictably.

"The beautiful thing is that you start with one line, expand them indefinitely and generate as many as you want," said Lanza. "It's a literally inexhaustible source of cells for therapy."

Lanza's team allowed a small culture of embryonic stem cells -- naturally capable of becoming any other type of tissue in the body -- to divide until it numbered a few billion cells. These they treated with a chemical cocktail that coaxed the cells into whatever type they wanted: A, B or O.

If they'd started with a type O-negative line, said Lanza, they could just as easily have made that, too.

Tests showed the blood cells to be identical to each other, and able to carry oxygen as efficiently as their natural counterparts.

The Red Cross described the work, published today in Blood, as "pioneering." However, they warned against premature celebration.

"At this stage, the work is very promising, but has not progressed to the stage where the cultured cells are fully equivalent" to natural cells, said the organization in a statement. "Much more work will yet be needed before this becomes a practical reality."

The most pressing uncertainty is safety: Embryonic stem cells are sometimes unpredictable and can develop genetic mutations during chemical reprogramming, leading to future side effects.

Blood cells, however, don't have any DNA -- they lose their nuclei as they develop from stem cells -- and don't divide, instead being broken down by the body when their four-month life cycle ends. That, said Lanza, should reduce the possibility of complications.

"You don't have to worry about anything lifelong," he said. "They'll be gone no matter what."

The ethics are potentially problematic, as embryonic stem cells ultimately originate in an embryo that is destroyed during their harvest -- a process that some religious conservatives equate with murder.

But Lanza said his technique could also work with stem cells produced by de-differentiation, a new and ethically trouble-free process during which adult cells regress into an embryonic state.

De-differentiated cells have a tendency to go cancerous -- but because blood cells are DNA-free, said Lanza, they could be safe in this particular application.

If Lanza's technique works, it will be a boon wherever blood transfusions are needed, but especially in places where type O-negative blood is not immediately available, such as emergency rooms and battlefields.

"There's always a great demand for type O blood," said Red Cross spokeswoman Molly Dalton. "It's always a worry that we don't have enough."

Biological properties and enucleation of red blood cells from human embryonic stem cells [Blood]

Image: WikiMedia Commons

Correction: I originally stated that Lanza's team made type O-negative blood; it was type O blood that they made -- still versatile, but not quite the universal grail of type O-negative. However, Lanza said that the technique could just as easily make O-negative, provided one started with an O-negative stem cell line -- something they did not possess (and does not appear to exist in any of the embryonic stem cell lines currently eligible for federal research funding.) "As soon as you get one line, it's immortal," he said.

My apologies for this mistake.

---
http://blog.wired.com/wiredscience/2008/08/universal-blood.html

[If they can make this without the embryonic stem cells, this avoids the ethical issues of consuming our young--making a market in (incentive to kill embryos in) cannibalism.]

Mark said...

Muscle stem cell advance hailed

Transplanting adult stem cells into mice with an illness like muscular dystrophy (MD) helped rebuild muscle structure and strength, a study says.

The work by Harvard University, published in the journal Cell, boosts the prospect of similar treatments for people with the condition one day.

There is no cure for the disease, which is inherited and causes rapid and progressive weakening of muscle tissue.

About 1 in every 20,000 births in the

UK are affected by muscular dystrophy.

The idea behind stem cell therapy is to find a way to boost the body's ability to replace or produce new tissues.

Stem cells can have the ability to form a wide variety of tissue types, and the Harvard team focused on adult muscle stem cells, which specialise in generating new muscle cells in response to growth or injury.

They bred mice which have a faulty dystrophin gene, the same problem which causes Duchenne MD in humans.

They then took adult muscle stem cells from other mice and injected them into the diseased mice's muscles.

One of the challenges in this approach is finding the correct cells, but the researchers developed a way to identify them using particular proteins found of their surface.

Once the stem cells were in place, they spread throughout the muscle, producing new cells and improved the way it worked.

Immune system

They also persisted in the stem cell form in a "reservoir", suggesting they could offer a longer-term benefit.

Dr Amy Wagers, who led the project, said: "This study indicates the presence of renewing muscle stem cells in adult skeletal muscle, and demonstrates the potential benefit of stem cell therapy for the treatment of muscle degenerative diseases such as muscular dystrophy."

She said that as well as offering a potential treatment in humans, understanding how the stem cells worked could help produce other therapies to boost the process in humans.

One of the problems of using adults stem cells from a donor would be the possibility of immune system rejection, but, in mice at least, the technique did not require the recipient's immune system to be suppressed.

However, Dr Wagers said that one obstacle to using the cells in MD was finding a way to distribute the cells to every affected muscle throughout the body.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/7500523.stm

Published: 2008/07/10 23:24:53 GMT

Mark said...

Physicists Kill Viruses With Rife's Genius - NO Credit Given

Vibrational Medicine - Scientists Destroy Viruses By Blasting Them With Resonant Frequencies

By David Gutierrez
9-1-2008

(NaturalNews) -- Physicists at Arizona State University say they have developed a method to calculate the exact frequency that it would take to shake a virus to death, according to an article published in the journal Physical Review Letters.

Researchers have discovered that when viruses are bombarded with laser pulses of the right frequency, they shake apart.

This arises from an inherent characteristic of all objects called a "resonant frequency," which is the frequency at which an object naturally vibrates.

Resonant frequencies are the key to stringed instruments, in which a string of a certain material, thickness and length has a resonant frequency that produces a specific musical note. But resonant frequencies can also cause objects to shake so uncontrollably that their stability is undermined, as when a wind shook the Tacoma Narrows Bridge at its resonant frequency in 1940, causing it to collapse.

Because the shell of a single virus can contain millions of atoms, it is difficult to calculate a given virus' resonant frequency except by trial and error. But in the current study, researchers successfully calculated the resonant frequency of a simple satellite tobacco necrosis virus.

The next step for the researchers is to determine if the same technique will work for other, more complex viruses.

Although practical applications are probably a long way off, [NONSENSE, just look up the Rife-established frequencies...] vibrational antiviral treatments have a number of benefits over chemical approaches.

First of all, while many antiviral drugs are very harsh on the body and have dangerous or debilitating side effects, the frequencies used to disrupt the viruses should have no effect on human or even bacterial cells, which are much larger and consequently have significantly lower resonant frequencies.

In addition, because a resonant frequency is an inherent characteristic of a virus' makeup, researchers say it is unlikely that resistance to it could develop.

Among the obstacles toward creating vibrational antiviral therapy is the fact that lasers have trouble penetrating the skin. Researchers have suggested that ultrasound could be used instead, or perhaps a dialysis-type machine that cycles of blood out of the body, irradiates it, then cycles it back in.

http://www.naturalnews.com:80/023855.html

Or it could be something like Gene Koonce's Vibe Machine tuned to different settings for different bacteria and viruses...

Mark said...

Catechin

Catechins are polyphenolic antioxidant plant metabolites.

They belong to the family of flavonoids and, to be more specific, flavan-3-ols.

These compounds are abundant in teas derived from the tea-plant Camellia sinensis as well as in some cocoas and chocolates (made from the seeds of Theobroma cacao).

Contents

* 1 Catechin, epicatechin, gallocatechin, epigallocatechin, and the gallates
* 2 Sources of catechins
* 3 Health benefits of catechins
* 4 See also
* 5 References
* 6 External links

[edit] Catechin, epicatechin, gallocatechin, epigallocatechin, and the gallates

Catechin and epicatechin are epimers, with (-)-epicatechin and (+)-catechin being the most common optical isomers found in nature.

Catechin was first isolated from the plant extract catechu, from which it derives its name. Heating catechin past its point of decomposition releases pyrocatechol, which explains the common origin of the names of these compounds.

Epigallocatechin and gallocatechin contain an additional phenolic hydroxyl group when compared to epicatechin and catechin, respectively, similar to the difference in pyrogallol compared to pyrocatechol.

Catechin gallates are gallic acid esters of the catechins; such as EGCG (epigallocatechin gallate), which is commonly the most abundant catechin in tea.

[edit] Sources of catechins

Catechins constitute about 25% of the dry weight of fresh tea leaf[1], although total catechin content varies widely depending on clonal variation, growing location, seasonal/ light variation, and altitude. They are present in nearly all teas made from Camellia sinensis, including white tea, green tea, black tea and Oolong tea.

Catechins are also present in the human diet in chocolate[2], fruits, vegetables and wine[3] and are found in many other plant species[4].

Epigallocatechin gallate is the most abundant catechin in tea.


Another stereoisomer, (-)-catechin, is released from the roots of the invasive weed, spotted knapweed.

It acts as an herbicide to inhibit competition by a wide range of other plant species. [5]. This phytotoxic compound inhibits seed germination and growth.

[edit] Health benefits of catechins

The health benefits of catechins have been studied extensively in humans and in animal models.

Reduction in atherosclerotic plaques was seen in animal models.[6] Reduction in carcinogenesis was seen in vitro.[7]

Many studies on health benefits have been linked to the catechin content. According to Norman Hollenberg, professor of medicine at Harvard Medical School, epicatechin can reduce the risk of four of the major health problems: stroke, heart failure, cancer and diabetes. He studied the Kuna people in Panama, who drink up to 40 cups of cocoa a week, and found that the prevalence of the “big four” is less than 10%.


He believes that epicatechin should be considered essential to the diet and thus classed as a vitamin.[4]Science Daily March 12, 2007

According to one researcher[8] epigallocatechin-3-gallate is an antioxidant that helps protect the skin from UV radiation-induced damage and tumor formation.

Green tea catechins have also been shown to possess antibiotic properties due to their role in disrupting a specific stage of the bacterial DNA replication process.[9] White tea typically contains higher level of catechins. [10]

Catechins, when combined with habitual exercise, have been shown to delay some forms of aging. Mice fed catechins showed decreased levels of aging.

Oxidative stress was lowered in cell mitochondria, as well as increase in mRNA transcription of mitochondria related proteins. [11]

The Lancet medical journal has warned[12] against increase one’s intake of dark chocolate in order to improve health, because the beneficial compounds are sometimes removed due to their bitter taste without an indication on the label, and because the fat, sugar, and calories of chocolate increase the risk for heart disease, unless balanced by a reduction in the intake of other foods.

[edit] See also

* Quercetin
* Flavonoid
* Camellia sinensis
* Cocoa
* Tannin
* Polyphenol
* Proanthocyanidin
* Polyphenon

[edit] References

1. ^ Balentine DA, Harbowy ME and Graham HN, Tea: the Plant and its Manufacture; Chemistry and Consumption of the Beverage in Caffeine (1998), ed. G Spiller
2. ^ Hammerstone JF, Lazarus SA, Schmitz HH Procyanidin content and variation in some commonly consumed foods. J Nutr, 130, 2086S–2092S (2000)
3. ^ Ruidavets JB, Teissedre PL, Ferrieres J, Carando S, Bougard G, Cabanis JC (2000) Catechin in the Mediterranean diet : vegetable, fruit or wine? Atherosclerosis, 153, 101-117
4. ^ The Flavonoids ed. JB Harborne, TJ Mabry, and H Mabry (1975)
5. ^ Harsh Pal Bais, Travis S. Walker, Frank R. Stermitz, Ruth A. Hufbauer, and Jorge M. Vivanco, Plant Physiol, April 2002, Vol. 128, pp. 1173-1179 [[1]]
6. ^ Chyu, K.-Y. (2004). "Differential effects of green tea-derived catechin on developing versus established atherosclerosis in apolipoprotein E-null mice". Circulation 109: 2448. doi:10.1161/01.CIR.0000128034.70732.C2. PMID 15136500. Circulation 2004 May 25;109(20):2448-53
7. ^ "EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis" Int J Oncol. 2004 Mar;24(3):703-10
8. ^ Santosh Katiyar, UAB associate professor of dermatology, J. Nutritional Biochemistry, May 2007
9. ^ Helena Gradisar, Primoz Pristovsek, Andreja Plaper, Roman Jerala. Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site. J Med Chem. 2007 Jan 25;50 (2):264-71
10. ^ "New" white tea, surprisingly, may have a healthful edge. Environmental Nutrition. Sept 2003. FindArticles.com. 10 Dec. 2007. [2]
11. ^ Tea catechin ingestion combined with habitual exercise suppresses the aging-associated decline in physical performance in senescence-accelerated mice. [3]
12. ^ The Lancet Student » Archive » The Lancet Digest December 22nd 2007

[edit] External links

* Micronutrient Information Center - Flavonoids
* Tea biochemistry
* Review of a study on green-tea catechins
* Cocoa 'vitamin' health benefits could outshine penicillin
* UK MSN - How cocoa beats killer diseases by Ross Chainey 12/03/07
* (-)Epicatechin mediates beneficial effects of flavonol-rich cocoa on vascular function in humans.

Retrieved from "http://en.wikipedia.org/wiki/Catechin"
Categories: Alcohols | Flavonoids | Phenols | Benzenediols | Antioxidants | Dietary antioxidants
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* All text is available under the terms of the GNU Free Documentation License. (See Copyrights for details.)

---
http://en.wikipedia.org/w/index.php?title=Catechin&printable=yes

BioregionalState said...

[continued from above]

1.

Phytonutrients

The fruits of some persimmon varieties contain the tannins catechinand gallocatechin,[8] as well as the anti-tumor compounds betulinic acid and shibuol, although the latter may also cause gastrointestinal problems.

[edit] Medical precaution

Unripened persimmons contain the soluble tannin shibuol, which, upon contact with a weak acid, polymerizes in the stomach and forms a gluey coagulum that can affix with other stomach matter.[9]

[AVOID UNRIPE PERSIMMONS THOUGH:]

The Merck Manual of Diagnosis and Therapy notes that consumption of persimmons has been known to cause bezoars that require surgery in over 90% of cases. More than 85% phytobezoars are caused by ingestion of unripened persimmons[10]. Persimmon bezoars often occur in epidemics in regions where the fruit is grown.[11][12] Horses may develop a taste for the fruit growing on a tree in their pasture and overindulge also, making them quite ill. It is often advised that persimmons should not be eaten with crab meat[13][14][15], nor should they be eaten on an empty stomach.


...


Ethnomedical uses

* In traditional Chinese medicine the fruit regulates ch'i

* The raw fruit is used to treat constipation and hemorrhoids, and to stop bleeding. As such, it is not a good idea to consume too many persimmons at once- they can induce diarrhea.

* The cooked fruit is used to treat diarrhea and dysentery


---
http://en.wikipedia.org/wiki/Persimmon

2.

Betulinic acid is a naturally occurring pentacyclic triterpenoid which has anti-retroviral, anti-malarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. [1]

It is found in the bark of several species of plants, including the Ber tree (Ziziphus mauritiana), the white birch (Betula pubescens), [2] and many other plants such as the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas a member of the persimmon family, Tetracera boiviniana, the jambul (Syzygium formosanum), [3] flowering quince (Chaenomeles sinensis), [4] and Pulsatilla chinensis. [5]

Contents

* 1 Anti-tumor activity
* 2 Mode of action
* 3 Anticancer derivatives
* 4 See also
* 5 References

[edit] Anti-tumor activity

In 1995, betulinic acid was reported as a selective inhibitor of human melanoma. [6] Then it was demonstrated, that betulinic acid induces apoptosis [self-destroying cell death, i.e., cancer kills itself] in human melanoma in vitro and in vivo model systems.[7] Currently it is undergoing development with assistance from the Rapid Access to Intervention Development program of the National Cancer Institute. [2]

Also betulinic acid was found active against neuroectodermal (neuroblastoma, medulloblastoma, Ewing's sarcoma[8]) and malignant brain tumors,[3][9] ovarian carcinoma,[3] in human leukemia HL-60 cells,[5] malignant head and neck squamous cell carcinoma SCC25 and SCC9 cell lines. [10]

In contrast, epithelial tumors, such as breast carcinoma, colon carcinoma, small cell lung carcinoma and renal cell carcinoma as well as T-cell leukemia cells were completely refractory to treatment with betulinic acid.[8]

[edit] Mode of action

Regarding the mode of action of betulinic acid, little is known about its antiproliferative and apoptosis-inducing mechanisms. [a stereoisomer of a close chemical relative is generated by a weed mentioned above to keep out other species so it can establish itself.]

In neuroectodermal tumor cells betulinic acid–induced apoptosis is accompanied by caspase activation, mitochondrial membrane alterations and DNA fragmentation.[8][10] Caspases are produced as inactive proenzymes, which are proteolytically processed to their active forms. These proteases can cooperate in proteolytic cascades, in which caspases activate themselves and each other. The initiation of the caspases cascade may lead to the activation of endonucleases like caspase-activated DNAase (CAD). After activation CAD contributes to DNA degradation.[10] Betulinic acid induces apoptosis by direct effects on mitochondria, leading to cytochrome-c release, which in turn regulates the "downstream" caspase activation.[10] Betulinic acid bypasses resistance to CD95 and doxorubicin-mediated apoptosis, due to different molecular mechanism of betulinic acid-induced apoptosis. [Thus it avoids the heart toxciticy of a whole class of doxorubicins: inset:

[[[
Doxorubicin (INN, pronounced /ˌdɒksəˈruːbəsɪn/; trade name Adriamycin; also known as hydroxydaunorubicin) is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines it intercalates DNA. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.

The drug is administered intravenously. It may be sold under the brand names Adriamycin PFS, Adriamycin RDF, or Rubex.[2] Doxil is a liposome-encapsulated form of doxorubicin made by Ben Venue Laboratories for Johnson & Johnson. The main benefits of this form are a reduction in cardiotoxicity. It is photosensitive and it is often covered by an aluminum bag to prevent light from affecting it.

Contents

* 1 History
* 2 Biosynthesis
* 3 Mechanism of action
* 4 Clinical use
o 4.1 Experimental therapy
* 5 Side effects
* 6 See also
* 7 References
* 8 External links

[edit] History

See also: History of cancer chemotherapy

The history of doxorubicin can be traced back to the 1950s, when an Italian research company, Farmitalia Research Laboratories, began an organized effort to find anticancer compounds from soil-based microbes. A soil sample was isolated from the area surrounding the Castel del Monte, a 13th century castle. A new strain of Streptomyces peucetius which produced a bright red pigment was isolated, and an antibiotic was produced from this bacterium that was found to have good activity against murine tumors. Since a group of French researchers discovered the same compound at about the same time, the two teams named the compound daunorubicin, combining the name Dauni, a pre-Roman tribe that occupied the area of Italy where the compound was isolated, with the French word for ruby, rubis, describing the color.[3] Clinical trials began in the 1960s, and the drug saw success in treating acute leukemia and lymphoma. However, by 1967, it was recognized that daunorubicin could produce fatal cardiac toxicity.[4]

Researchers at Farmitalia soon discovered that changes in biological activity could be made by minor changes in the structure of the compound. A strain of Streptomyces was mutated using N-nitroso-N-methyl urethane and this new strain produced a different, red-colored antibiotic. They named this new compound Adriamycin, after the Adriatic Sea, and the name was later changed to doxorubicin to conform to the established naming convention.[5] Doxorubicin showed better activity than daunorubicin against murine tumors, and especially solid tumors. It also showed a relatively higher therapeutic index, yet the cardiotoxicity remained.[6]

]]]


Controversial is a role of p53 in betulinic acid-induced apoptosis. Fulda suggested p53-independent mechanism of the apoptosis, basing on fact of no accumulation of wild-type p53 detected upon treatment with the betulinic acid, whereas wild-type p53 protein strongly increased after treatment with doxorubicin.[8] The suggestion is supported by study of Raisova.[11]

On the other hand Rieber suggested that betulinic acid exerts its inhibitory effect on human metastatic melanoma partly by increasing p53.[12] [evidence though?]

The study also demonstrated preferential apoptotic effect of betulinic acid on C8161 metastatic melanoma cells, with greater DNA fragmentation and growth arrest and earlier loss of viability than their non-metastatic C8161/neo 6.3 counterpart.[12]

Comparing the betulinic acid with other treatment modes, Zuco demonstrated that it was more than 10 times less potent than doxorubicin [thus less toxic to the heart] (IC50 4.5 μg/ml Vs IC50 0.21-034 μg/ml in doxorubicin) and showed an in vitro antiproliferative activity against melanoma and non-melanoma cell lines, including those resistant to doxorubicin.

On the human normal dermatoblast cell line betulinic acid was 2-5 times less toxic than doxorubicin.[3]

The ability of betulinic acid to induce two different effects (cytotoxic and cytostatic) on two clones derived from the same human melanoma metastasis suggests that the development of clones resistant to this agent will be more unlikely, than that to conventional cytotoxic drugs. Moreover in spite of the lower potency compared with doxorubicin, betulinic acid seems to be selective for tumor cells with minimal toxicity against normal cells.[3]

The effect of betulinic acid on melanoma cell lines is stronger than its growth-inhibitory effect on primary melanocytes.[13]Study of combination of betulinic acid with γ-irradiation showed clearly additive effects, and indicates that they differ in their mode of action.[13]

[edit] Anticancer derivatives

A major inconvenience for the future clinical development of betulinic acid and analogues resides in their poor solubility in aqueous media like blood serum and polar solvents used for bioassays. [so...? in other words, just eat it natural...]

To circumvent this problem of hydrosolubility and to enhance pharmacological properties, many derivatives were synthesized and evaluated for cytotoxic activity. A study showed that C-20 modifications involve the loss of cytotoxicity. Another study demonstrated the importance of the presence of the COOH group since compounds substituted at this position like lupeol and methyl betulinate were less active on human melanoma than betulinic acid.

Moreover, some C-28 amino acids and C-3 phthalates derivatives exhibited higher cytotoxic activity against cancer cell lines with improved selective toxicity and water solubility. Chatterjee and co-workers obtained the 28-O-β-D-glucopyranoside of betulinic acid by microbial transformation with Cunninghamella species while Baglin and co-workers obtained it by organic synthesis.

This glucoside did not exhibit any significant in vitro activity on human melanoma (MEL-2) and human colorectal adenocarcinoma (HT-29) cell lines which confirms the importance of the carboxylic acid function to preserve the cytotoxicity. Recently, Gauthier and coworkers have synthesized a series of 3-O-glycosides of betulinic acid which exhibited a strongly potent in vitro anticancer activity against human cancer cell lines.[14]

[edit] See also

* oleanolic acid
* moronic acid

---
http://en.wikipedia.org/wiki/Betulinic_acid

3.

p53 (also known as protein 53 or tumor protein 53), is a transcription factor encoded by the TP53 gene. p53 is important in multicellular organisms, where it regulates the cell cycle and thus functions as a tumor suppressor that is involved in preventing cancer. As such, p53 has been described as "the guardian of the genome," "the guardian angel gene," and the "master watchman," referring to its role in conserving stability by preventing genome mutation.[1]

The name p53 is in reference to its apparent molecular mass: it runs as a 53 kilodalton (kDa) protein on SDS-PAGE. But based on calculations from its amino acid residues, p53's mass is actually only 43.7kDa. This difference is due to the high number of proline residues in the protein which slow its migration on SDS-PAGE[citation needed], thus making it appear larger than it actually is. This effect is observed with p53 from a variety of species, including humans, rodents, frogs and fish.

Contents


* 1 Gene
* 2 Structure
* 3 Functional significance
* 4 Regulation of p53 activity
* 5 Role in disease
* 6 History
* 7 Other names
* 8 References
* 9 Additional images
* 10 External links

[edit] Gene

In humans, p53 is encoded by the TP53 gene located on the short arm of chromosome 17 (17p13.1).

The gene is on different locations in other animals:

* Mouse - chromosome 11
* Rat - chromosome 10
* Dog - chromosome 5
* Pig - chromosome 12

(Italics are used to distinguish the TP53 gene name from the protein it encodes.)

[edit] Structure

Human p53 is 393 amino acids long and has seven domains:

* An N-terminal transcription-activation domain (TAD), also known as activation domain 1 (AD1) which activates transcription factors: residues 1-42.
* An activation domain 2 (AD2) important for apoptotic activity: residues 43-63.
* A Proline rich domain important for the apoptotic activity of p53: residues 80-94.
* A central DNA-binding core domain (DBD). Contains one zinc atom and several arginine amino acids: residues 100-300.
* A nuclear localization signalling domain, residues 316-325.
* A homo-oligomerisation domain (OD): residues 307-355. Tetramerization is essential for the activity of p53 in vivo.
* A C-terminal involved in downregulation of DNA binding of the central domain: residues 356-393.[2]

Mutations that deactivate p53 in cancer usually occur in the DBD.

Most of these mutations destroy the ability of the protein to bind to its target DNA sequences, and thus prevents transcriptional activation of these genes. As such, mutations in the DBD are recessive loss-of-function mutations.

Molecules of p53 with mutations in the OD dimerise with wild-type p53, and prevent them from activating transcription. Therefore OD mutations have a dominant negative effect on the function of p53.

Wild-type p53 is a labile protein, comprising folded and unstructured regions which function in a synergistic manner.[3]

[edit] Functional significance

p53 has many anti-cancer mechanisms:

* It can activate DNA repair proteins when DNA has sustained damage.

* It can also hold the cell cycle at the G1/S regulation point on DNA damage recognition (if it holds the cell here for long enough, the DNA repair proteins will have time to fix the damage and the cell will be allowed to continue the cell cycle.)

* It can initiate apoptosis, the programmed cell death, if the DNA damage proves to be irreparable.

p53 pathway: In a normal cell p53 is inactivated by its negative regulator, mdm2. Upon DNA damage or other stress, various pathways will lead to the dissociation of the p53 and mdm2 complex.

[Same principle of the 'on' and 'off' of growth hormones 'on' and B17/laetrile 'off' (in apricot seeds)... A lot of cancers keep growing because the body lacks these 'off' chemicals like B17. Back to another topic, p53:]

Once activated, p53 will either induce a cell cycle arrest to allow repair and survival of the cell or apoptosis to discard the damage cell. How p53 makes this choice is currently unknown.

p53 pathway: In a normal cell p53 is inactivated by its negative regulator, mdm2. Upon DNA damage or other stress, various pathways will lead to the dissociation of the p53 and mdm2 complex. Once activated, p53 will either induce a cell cycle arrest to allow repair and survival of the cell or apoptosis to discard the damage cell. How p53 makes this choice is currently unknown.

p53 is central to many of the cell's anti-cancer mechanisms. It can induce growth arrest, apoptosis and cell senescence. In normal cells p53 is usually inactive, bound to the protein MDM2 (also called HDM2 in humans), which prevents its action and promotes its degradation by acting as ubiquitin ligase.

Active p53 is induced after the effects of various cancer-causing agents such as UV radiation, oncogenes and some DNA-damaging drugs. DNA damage is sensed by 'checkpoints' in a cell's cycle, and causes proteins such as ATM, CHK1 and CHK2 to phosphorylate p53 at sites that are close to or within the MDM2-binding region and p300-binding region of the protein.

Oncogenes also stimulate p53 activation, mediated by the protein p14ARF. Some oncogenes can also stimulate the transcription of proteins which bind to MDM2 and inhibit its activity.

Once activated p53 activates expression of several genes including one encoding for p21.

p21 binds to the G1-S/CDK and S/CDK complexes (molecules important for the G1/S transition in the cell cycle) inhibiting their activity.

p53 has many anticancer mechanisms, and plays a role in apoptosis, genetic stability, and inhibition of angiogenesis.

The p53 gene has been mapped to chromosome 17. In the cell, p53 protein binds DNA, which in turn stimulates another gene to produce a protein called p21 that interacts with a cell division-stimulating protein (cdk2).

When p21 is complexed with cdk2 the cell cannot pass through to the next stage of cell division. Mutant p53 can no longer bind DNA in an effective way, and as a consequence the p21 protein is not made available to act as the 'stop signal' for cell division. Thus cells divide uncontrollably, and form tumors.[4]

Recent research has also linked the p53 and RB1 pathways, via p14ARF, raising the possibility that the pathways may regulate each other.[5] [note on that below]

Research published in 2007 showed when p53 expression is stimulated by sunlight, it begins the chain of events leading to tanning.[6][7]

[edit] Regulation of p53 activity

p53 becomes activated in response to a myriad of stress types, which include but is not limited to DNA damage (induced by either UV, IR or chemical agents,such as hydrogen peroxide), oxidative stress, osmotic shock, ribonucleotide depletion and deregulated oncogene expression.

This activation is marked by two major events.

Firstly, the half-life of the p53 protein is increased drastically, leading to a quick accumulation of p53 in stressed cells.

Secondly, a conformational change forces p53 to take on an active role as a transcription regulator in these cells.

The critical event leading to the activation of p53 is the phosphorylation of its N-terminal domain. The N-terminal transcriptional activation domain contains a large number of phosphorylation sites and can be considered as the primary target for protein kinases transducing stress signals.

[[[

Phosphorylation is the addition of a phosphate (PO4) group to a protein molecule or a small molecule. It can also be thought of as the introduction of a phosphate group into an organic molecule. Its prominent role in biochemistry is the subject of a very large body of research (as of February 2008, the Medline database returns nearly 148,000 articles on the subject, largely on protein phosphorylation)....Reversible phosphorylation of proteins is an important regulatory mechanism that occurs in both prokaryotic and eukaryotic organisms.[4][5][6][7] Enzymes called kinases (phosphorylation) and phosphatases (dephosphorylation) are involved in this process. Many enzymes and receptors are switched "on" or "off" by phosphorylation and dephosphorylation. Reversible phosphorylation results in a conformational change in the structure in many enzymes and receptors, causing them to become activated or deactivated. Phosphorylation usually occurs on serine, threonine, and tyrosine residues in eukaryotic proteins.

In addition, phosphorylation occurs on the basic amino acid residues histidine or arginine or lysine in prokaryotic proteins[4][5].

The addition of a phosphate (PO4) molecule to a polar R group of an amino acid residue can turn a hydrophobic portion of a protein into a polar and extremely hydrophilic portion of molecule.

In this way it can introduce a conformational change in the structure of the protein via interaction with other hydrophobic and hydrophilic residues in the protein.

One such example of the regulatory role that phosphorylation plays is the p53 tumor suppressor protein.

The p53 protein is heavily regulated[8] and contains more than 18 different phosphorylation sites.

Activation of p53 can lead to cell cycle arrest, which can be reversed under some circumstances, or apoptotic cell death[9] This activity occurs only in situations wherein the cell is damaged or physiology is disturbed in normal healthy individuals.

Upon the deactivating signal, the protein becomes dephosphorylated again and stops working. This is the mechanism in many forms of signal transduction, for example the way in which incoming light is processed in the light-sensitive cells of the retina.

Regulatory roles of phosphorylation include

* Biological thermodynamics of energy-requiring reactions
o Phosphorylation of Na+/K+-ATPase during the transport of sodium (Na+) and potassium(K+) ions across the cell membrane in osmoregulation to maintain homeostasis of the body's water content.

* Mediates enzyme inhibition
o Phosphorylation of the enzyme GSK-3 by AKT (Protein kinase B) as part of the insulin signaling pathway.[10]
o Phosphorylation of src tyrosine kinase (pronounced "sarc") by C-terminal Src kinase (Csk) induces a conformational change in the enzyme, resulting in a fold in the structure, which masks its kinase domain, and is thus shut "off".[11]

* Important for protein-protein interaction via "recognition domains."
o Phosphorylation of the cytosolic components of NADPH oxidase, a large membrane-bound, multi-protein enzyme present in phagocytic cells, plays an important role in the regulation of protein-protein interactions in the enzyme.[12]

* Important in protein degradation.
o In the late 1990s, it was recognized that phosphorylation of some proteins causes them to be degraded by the ATP-dependent ubiquitin/proteasome pathway. These target proteins become substrates for particular E3 ubiquitin ligases only when they are phosphorylated.

[edit] Signaling networks

Elucidating complex signaling pathway phosphorylation events can be difficult.

In a cellular signaling pathways, a protein A phosphorylates protein B, and B phosphorylates C.

However, in another signaling pathway, protein D phosphorylates A, or phosphorylates protein C.

Global approaches such as phosphoproteomics the study of phosphorylated proteins, which is a sub-branch of proteomics combined with mass spectrometry-based proteomics, have been utilised to identify and quantify dynamic changes in phosphorylated proteins over time.

These techniques are becoming increasingly important for the systematic analysis of complex phosphorylation networks.[13] They have been successfully used to identify dynamic changes in the phosphorylation status of more than 6000 sites after stimulation with epidermal growth factor.[13][14]

[edit] Protein phosphorylation sites

There are thousands of distinct phosphorylation sites in a given cell since:

1) There are thousands of different kinds of proteins in any particular cell (such as a lymphocyte).

2) It is estimated that 1/10th to 1/2 of proteins are phosphorylated (in some cellular state).

3) Phosphorylation often occurs on multiple distinct sites on a given protein.

Since phosphorylation of any site on a given protein can change the function or localization of that protein, understanding the "state" of a cell requires knowing the phosphorylation state of its proteins.

For example, if amino acid Serine-473 ("S473") in the protein AKT is phosphorylated, AKT is, in general, functionally active as a kinase. If not, it is an inactive kinase.

[edit] Types of phosphorylation

See also kinases for more details on the different types of phosphorylation

Within a protein, phosphorylation can occur on several amino acids.

Phosphorylation on serine is the most common, followed by threonine.

[[[

Serine

It is one of the 20 naturally occurring proteinogenic amino acids. Its codons are UCU, UCC, UCA, UCG, AGU and AGC. Only the L-stereoisomer appears naturally in proteins. It is not essential to the human diet, since it is synthesized in the body from other metabolites, including glycine. Serine was first obtained from silk protein, a particularly rich source, in 1865. Its name is derived from the Latin for silk, sericum. Serine's structure was established in 1902. By virtue of the hydroxyl group, serine is classified as a polar amino acid.

[edit] Biosynthesis

The biosynthesis of serine starts with the oxidation of 3-phosphoglycerate to 3-phosphohydroxypyruvate and NADH. Reductive amination of this ketone followed by hydrolysis gives serine. Serine hydroxymethyltransferase catalyzes the reversible, simultaneous conversions of L-serine to glycine (retro-aldol cleavage) and 5,6,7,8-tetrahydrofolate to 5,10-methylenetetrahydrofolate (hydrolysis).[2]

[edit] Chemical synthesis

Racemic serine can be prepared from methyl acrylate via several steps.[3]

[edit] Function

[edit] Metabolic

Serine is important in metabolism in that it participates in the biosynthesis of purines and pyrimidines. [i.e., the building blocks of the outside and inside of DNA.]

It is also the precursor to several amino acids, including glycine, cysteine, and, in bacteria, tryptophan. It is also the precursor to numerous of other metabolites, including sphingolipids.

[[[Sphingolipids are commonly believed to protect the cell surface against harmful environmental factors by forming a mechanically stable and chemically resistant outer leaflet of the plasma membrane lipid bilayer. Certain complex glycosphingolipids were found to be involved in specific functions, such as cell recognition and signaling. The first feature depends mainly on the physical properties of the sphingolipids, whereas signaling involves specific interactions of the glycan structures of glycosphingolipids with similar lipids present on neighboring cells or with proteins.

Recently, relatively simple sphingolipid metabolites, such as ceramide and sphingosine-1-phosphate, have been shown to be important mediators in the signaling cascades involved in apoptosis, proliferation, and stress responses.[1][2] Ceramide-based lipids self-aggregate in cell membranes and form separate phases less fluid than the bulk phospholipids. These sphingolipid-based microdomains, or "lipid rafts" were originally proposed to sort membrane proteins along the cellular pathways of membrane transport. At present, most research focuses on the organizing function during signal transduction.[3]

]]]


Serine is also a precursor to folate, which is the principal donor of one carbon fragments in biosynthesis.

[edit] Structural role

Serine plays an important role in the catalytic function of many enzymes. It has been shown to occur in the active sites of chymotrypsin, trypsin, and many other enzymes. The so-called nerve gases and many substances used in insecticides have been shown to act by combining with a residue of serine in the active site of acetylcholine esterase, inhibiting the enzyme completely. [that's how important it is, nerve gases only 'work' when they disable serine.]

The unmetabolized acetylcholine cannot be recycled into the nerve for signaling. This results in depletion of acetylcholine at the neuromuscular junction, resulting in the inability to control muscles, which results in asphyxiation, and death.

As a constituent (residue) of proteins, its side chain can undergo O-linked glycosylation, which may be functionally related to diabetes. It is one of three amino acid residues that are commonly phosphorylated by kinases during cell signaling in eukaryotes. Phosphorylated serine residues are often referred to as phosphoserine. Serine proteases are a common type of protease.

[edit] Signaling

D-serine, synthesized by serine racemase from L-serine, serves as a neuronal signal by activating NMDA receptors in the brain.[4]

[[[

The NMDA receptor (NMDAR) is an ionotropic receptor for glutamate (NMDA (N-methyl D-aspartate) is a name of its selective specific agonist). Activation of NMDA receptors results in the opening of an ion channel that is nonselective to cations. This allows flow of Na+ and small amounts of Ca2+ ions into the cell and K+ out of the cell.

Calcium flux through NMDARs is thought to play a critical role in synaptic plasticity, a cellular mechanism for learning and memory. The NMDA receptor is distinct in that it is both ligand-gated and voltage-dependent.

]]]

Threonine (abbreviated as Thr or T)[1] is an α-amino acid with the chemical formula HO2CCH(NH2)CH(OH)CH3. Its codons are ACU, ACA, ACC, and ACG. This essential amino acid is classified as polar. Together with serine and tyrosine, threonine is one of three proteinogenic amino acids bearing an alcohol group.

The threonine residue is susceptible to numerous posttranslational modifications. The hydroxy side chain can undergo O-linked glycosylation. In addition, threonine residues undergo phosphorylation through the action of a threonine kinase.

In its phosphorylated form, it can be referred to as phosphothreonine.

Contents


* 1 Allo-threonine
* 2 Biosynthesis
* 3 Metabolism
* 4 Sources
* 5 References
* 6 See also
* 7 External links

[edit] Allo-threonine

With two chiral centers, threonine can exist in four possible stereoisomers, or two possible diastereomers of L-threonine.

However, the name L-threonine is used for one single enantiomer, (2S,3R)-2-amino-3-hydroxybutanoic acid. The second diastereomer (2S,3S), which is rarely present in nature, is called L-allo-threonine.

[edit] Biosynthesis

As an essential amino acid, threonine is not synthesized in humans, hence we must ingest threonine in the form of threonine-containing proteins.

In plants and microorganisms, threonine is synthesized from aspartic acid via α-aspartyl-semialdehyde and homoserine. Homoserine undergoes O-phosphorylation; this phosphate ester undergoes hydrolysis concomitant with relocation of the OH group.[2] Enzymes involved in a typical biosynthesis of threonine include:

1. aspartokinase
2. α-aspartate semialdehyde dehydrogenase
3. homoserine dehydrogenase
4. homoserine kinase
5. threonine synthase.

Threonine biosynthesis

[edit] Metabolism

Threonine is metabolized in two ways:

* It is converted to pyruvate via threonine dehydrogenase. An intermediate in this pathway can undergo thiolysis with CoA to produce Acetyl-CoA and glycine.

* In humans, it is converted to alpha-ketobutyrate in a less common pathway via the enzyme serine dehydratase, and thereby enters the pathway leading to succinyl-CoA.

[edit] Sources

Foods high in threonine include cottage cheese, poultry, fish, meat, lentils, and sesame seeds.

]]]

Tyrosine phosphorylation is relatively rare. However, since tyrosine phosphorylated proteins are relatively easy to purify using antibodies, tyrosine phosphorylation sites are relatively well understood. Histidine and aspartate phosphorylation occurs in prokaryotes as part of two-component signaling and in some cases in eukaryotes in some signal transduction pathways[1].

[edit] Detection and characterization

Antibodies can be used as powerful tools to detect whether a protein is phosphorylated at a particular site.

Antibodies bind to and detect phosphorylation-induced conformational changes in the protein. Such antibodies are called phospho-specific antibodies; hundreds of such antibodies are now available. They are becoming critical reagents both for basic research and for clinical diagnosis.

Example of posttranslational modification detected on a 2D gel (spot boundaries delimited by analysis software, identification by mass spectrometry, P46462 is the protein ID in Expasy)

PTM (Posttranslational Modification) isoforms are easily detected on 2D gels. Indeed, phosphorylation replaces neutral hydroxyl groups on serines, threonines, or tyrosines with negatively-charged phosphates with pKs near 1.2 and 6.5.

Thus, below pH 5.5, [i.e., conditions in the blood that are cancer causing] phosphates add a single negative charge; near pH 6.5, they add 1.5 negative charges; above pH 7.5, [a healthy basic solution] they add 2 negative charges.

The relative amount of each isoform can also easily and rapidly be determined from staining intensity on 2D gels.

A detailed characterization of the sites of phosphorylation is very difficult, and the quantitation of protein phosphorylation by mass spectrometry requires isotopic internal standard approaches (Gerber et al., 2003). A relative quantitation can be obtained with a variety of differential isotope labeling technologies (Gygi et al., 2002, Goshe et al., 2003).

[edit] Other kinds

ATP, the "high-energy" exchange medium in the cell, is synthesized in the mitochondrion by addition of a third phosphate group to ADP in a process referred to as oxidative phosphorylation. ATP is also synthesized by substrate-level phosphorylation during glycolysis.

ATP is synthesized at the expense of solar energy by photophosphorylation in the chloroplasts of plant cells.

Phosphorylation of sugars is often the first stage of their catabolism.

It allows cells to accumulate sugars because the phosphate group prevents the molecules from diffusing back across their transporter.

[edit] External links

* Mammalian Phosphorylation Resource, which integrates information on available phospho-specific antibodies

* deltaMasses detection and localization of phosphorylations after mass spectrometry

* Functional analyses for site-specific phosphorylation of a target protein in cells (A Protocol)

]]]

The protein kinases that are known to target this transcriptional activation domain of p53 can be roughly divided into two groups.

A first group of protein kinases belongs to the MAPK family (JNK1-3, ERK1-2, p38 MAPK), which is known to respond to several types of stress, such as membrane damage, oxidative stress, osmotic shock, heat shock, etc... A second group of protein kinases (ATR, ATM, Chk1, Chk2, DNA-PK, CAK) is implicated in the genome integrity checkpoint, a molecular cascade that detects and responds to several forms of DNA damage caused by genotoxic stress.

In unstressed cells, p53 levels are kept low through a continuous degradation of p53. A protein called Mdm2 binds to p53 and transports it [unactivated] from the nucleus to the cytosol where it becomes degraded by the proteasome. Phosphorylation of the N-terminal end of p53 by the above-mentioned protein kinases disrupts Mdm2-binding [safety lock on it, thus freeing p53 to 'work'].

Other proteins, such as Pin1, are then recruited to p53 and induce a conformational change in p53 which prevents Mdm2-binding even more. [unlocked first, then activated 'actively' afterward, in the same phosphyloration, a staged 'warm up' of the system.]

Trancriptional coactivators, like p300 or PCAF, then acetylate the carboxy-terminal end of p53, exposing the DNA binding domain of p53, allowing it to activate or repress specific genes.

Deacetylase enzymes, such as Sirt1 and Sirt7, can deacetylate p53, leading to an inhibition of apoptosis.[8]

[edit] Role in disease

If the TP53 gene is damaged, tumor suppression is severely reduced.

People who inherit only one functional copy of the TP53 gene will most likely develop tumors in early adulthood, a disease known as Li-Fraumeni syndrome. [That's how important this pathway is.]

The TP53 gene can also be damaged in cells by mutagens (chemicals, radiation or viruses), increasing the likelihood that the cell will begin uncontrolled division.

More than 50 percent of human tumors contain a mutation or deletion of the TP53 gene.

Increasing the amount of p53, which may initially seem a good way to treat tumors or prevent them from spreading, is in actuality not a usable method of treatment, since it can cause premature aging. [yes, see another above post about healing and aging processes.][9]

However, restoring endogenous p53 function holds a lot of promise.[10]

Certain pathogens can also affect the p53 protein that the TP53 gene expresses. One such example, the Human papillomavirus (HPV), encodes a protein, E6, which binds the p53 protein and inactivates it.

This, in synergy with the inactivation of another cell cycle regulator, p105RB, allows for repeated cell division manifestested in the clinical disease of warts.

In healthy humans, the p53 protein is continually produced and degraded in the cell. The degradation of the p53 protein is, as mentioned, associated with MDM2 binding. In a negative feedback loop MDM2 is itself induced by the p53 protein.

However mutant p53 proteins often don't induce MDM2, and are thus able to accumulate at very high concentrations. Worse, mutant p53 protein itself can inhibit normal p53 protein levels.

[edit] History

p53 was identified in 1979 by Arnold Levine, David Lane, and Lloyd Old, working at Princeton University, Imperial Cancer Research Fund (UK), and Sloan-Kettering Memorial Hospital, respectively. It had been hypothesized to exist before as the target of the SV40 virus, a strain that induced development of tumors. The TP53 gene from the mouse was first cloned by Peter Chumakov of the Moscow Academy of Sciences in 1982,[11] and independently in 1983 by Moshe Oren (Weizmann Institute).

It was initially presumed to be an oncogene due to the use of mutated cDNA following purification of tumour cell mRNA.

Its character as a tumor suppressor gene was finally revealed in 1989 by Bert Vogelstein working at Johns Hopkins School of Medicine.

Warren Maltzman, of the Waksman Institute of Rutgers University first demonstrated that TP53 was responsive to DNA damage in the form of ultraviolet radiation.[12]

In a series of publications in 1991-92, Michael Kastan, Johns Hopkins University, reported that TP53 was a critical part of a signal transduction pathway that helped cells respond to DNA damage.

In 1993, p53 was voted molecule of the year by Science magazine.[13]

[edit] Other names

* Official protein name: Cellular tumor antigen p53
* Tumor suppressor p53
* Transformation-related protein 53 (TRP53)
* Phosphoprotein p53
* Antigen NY-CO-13

[edit] References

1. ^ Read, A. P.; Strachan, T. (1999). "Chapter 18: Cancer Genetics", Human molecular genetics 2. New York: Wiley. ISBN 0-471-33061-2.
2. ^ Harms KL, Chen X (2005). "The C terminus of p53 family proteins is a cell fate determinant". Mol. Cell. Biol. 25 (5): 2014–30. doi:10.1128/MCB.25.5.2014-2030.2005. PMID 15713654.
3. ^ Bell S, Klein C, Müller L, Hansen S, Buchner J (2002). "p53 contains large unstructured regions in its native state". J. Mol. Biol. 322 (5): 917–27. doi:10.1016/S0022-2836(02)00848-3. PMID 12367518.
4. ^ National Center for Biotechnology Information. "The p53 tumor suppressor protein". Genes and Disease. United States National Institutes of Health. Retrieved on 2008-05-28.
5. ^ Bates S, Phillips AC, Clark PA, Stott F, Peters G, Ludwig RL, Vousden KH (1998). "p14ARF links the tumour suppressors RB and p53". Nature 395 (6698): 124–5. doi:10.1038/25867. PMID 9744267.
6. ^ "Genome's guardian gets a tan started", New Scientist (March 17, 2007). Retrieved on 2007-03-29.
7. ^ Cui R, Widlund HR, Feige E, Lin JY, Wilensky DL, Igras VE, D'Orazio J, Fung CY, Schanbacher CF, Granter SR, Fisher DE (2007). "Central role of p53 in the suntan response and pathologic hyperpigmentation". Cell 128 (5): 853–64. doi:10.1016/j.cell.2006.12.045. PMID 17350573.
8. ^ Vakhrusheva O, Smolka C, Gajawada P, Kostin S, Boettger T, Kubin T, Braun T, Bober (March 2008). "Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice". Circ. Res. 102 (6): 703–10. doi:10.1161/CIRCRESAHA.107.164558. PMID 18239138.
9. ^ Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Igelmann H, Lu X, Soron G, Cooper B, Brayton C, Hee Park S, Thompson T, Karsenty G, Bradley A, Donehower LA (2002). "p53 mutant mice that display early ageing-associated phenotypes". Nature 415 (6867): 45–53. doi:10.1038/415045a. PMID 11780111.
10. ^ Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T (2007). "Restoration of p53 function leads to tumour regression in vivo". Nature 445 (7128): 661–5. doi:10.1038/nature05541. PMID 17251932.
11. ^ Chumakov P, Iotsova V, Georgiev G (1982). "[Isolation of a plasmid clone containing the mRNA sequence for mouse nonviral T-antigen]". Dokl Akad Nauk SSSR 267 (5): 1272–5. PMID 6295732.
12. ^ Maltzman W, Czyzyk L (1984). "UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells". Mol Cell Biol 4 (9): 1689–94. PMID 6092932.
13. ^ Koshland DE (1993). "Molecule of the year". Science 262 (5142): 1953. doi:10.1126/science.8266084. PMID 8266084.

---
http://en.wikipedia.org/wiki/P53

6.

The retinoblastoma protein (abbreviated pRb or Rb) is a tumor suppressor protein that is dysfunctional in many types of cancer.[1] One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide.

pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins.[2][3] Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer.

Contents


* 1 Name and genetics
* 2 Cell cycle suppression
* 3 Activation and inactivation
* 4 See also
* 5 References
* 6 Further reading
* 7 External links

[edit] Name and genetics

In humans, the protein is encoded by the RB1 gene located on 13q14.1-q14.2. If both alleles of this gene are mutated early in life, the protein is inactivated and results in development of retinoblastoma cancer, hence the name Rb. It is not known why an eye cancer results from a mutation in a gene that is important all over the body.[more phosphorlation in the eye as the high site/(sight) of it how signals transferred from light to the brain, just more of the phosphylration there in the eye?]

Two forms of retinoblastoma were noticed: a bilateral, familial form and a unilateral, sporadic form. Sufferers of the former were 6 times more likely to develop other types of cancer later in life[4]. This highlighted the fact that mutated Rb could be inherited and lent support to the two-hit hypothesis.

This states that only one working allele of a tumour suppressor gene is necessary for its function (the mutated gene is recessive), and so both need to be mutated before the cancer phenotype will appear.

In the familial form, a mutated allele is inherited along with a normal allele. In this case, should a cell sustain only one mutation in the other RB gene, all pRb in that cell would be ineffective at inhibiting cell cycle progression, allowing cells to divide uncontrollably and eventually become cancerous. Furthermore, as one allele is already mutated in all other somatic cells, the future incidence of cancers in these individuals is observed with linear kinetics[5]. The working allele need not undergo a mutation per se, as loss of heterozygosity is frequently observed in such tumours.

However, in the sporadic form, both alleles would need to sustain a mutation before the cell can become cancerous. This explains why sufferers of sporadic retinoblastoma are not at increased risk of cancers later in life, as both alleles are functional in all their other cells. Future cancer incidence in sporadic Rb cases is observed with polynomial kinetics, not exactly quadratic as expected because the first mutation must arise through normal mechanisms, and then can be duplicated by LOH to result in a tumour progenitor.

[edit] Cell cycle suppression

pRb prevents the cell from replicating damaged DNA by preventing its progression along the cell cycle through G1 (first gap phase) into S (synthesis phase).[6] pRb binds and inhibits transcription factors of the E2F family, which are composed of dimers of an E2F protein and a DP protein.[7] The transcription activating complexes of E2 promoter-binding–protein-dimerization partners (E2F-DP) can push a cell into S phase.[8][9][10][11][12] As long as E2F-DP is inactivated, the cell remains stalled in the G1 phase. When pRb is bound to E2F, the complex acts as a growth suppressor and prevents progression through the cell cycle.[3] The pRb-E2F/DP complex also attracts a histone deacetylase (HDAC) protein to the chromatin, further suppressing DNA synthesis.

[edit] Activation and inactivation

In the hypophosphorylated state, pRb is active and carries out its role as tumor suppressor by inhibiting cell cycle progression. Phosphorylation inactivates pRb. During the M-to-G1 transition, pRb is progressively dephosphorylated by PP1, returning to its growth-suppressive hypophosphorylated state .[3][13]

When it is time for a cell to enter S phase, complexes of cyclin-dependent kinases (CDK) and cyclins phosphorylate pRb, inhibiting its activity.[2][3][6][14] The initial phosphorylation is performed by Cyclin D/CDK4,6 and followed by additional phosphorylation by Cyclin E/CDK2. pRb remains phosphorylated throughout S, G2 and M phases.[3]

Phosphorylation of pRb allows E2F-DP to dissociate from pRb and become active.[3][9][6] When E2F is freed it activates factors like cyclins (e.g. Cyclin E and A), which push the cell through the cell cycle by activating cyclin-dependent kinases, and a molecule called proliferating cell nuclear antigen, or PCNA, which speeds DNA replication and repair by helping to attach polymerase to DNA.[8][6][11]

[edit] See also

* p53 - involved in the DNA repair support function of pRb

* Transcription coregulator

[edit] References

1. ^ Murphree A.L. and Benedict W.F. 1984. Retinoblastoma: clues to human oncogenesis in Science, 223(4640): 1028-1033. Entrez PubMed 6320372 Retrieved on January 24, 2007.
2. ^ a b Korenjak M. and Brehm A. 2005. E2F–Rb complexes regulating transcription of genes important for differentiation and development. Current Opinion in Genetics & Development, 15(5): 520-527.
3. ^ a b c d e f Münger K. and Howley P.M. 2002. Human papillomavirus immortalization and transformation functions. Virus Research, 89: 213–228.
4. ^ J Clin Oncol (2005) 23:2272
5. ^ Knudson 1971, Proc Acad Nat Sci USA 68:820
6. ^ a b c d Das S.K., Hashimoto T., Shimizu K., Yoshida T., Sakai T., Sowa Y., Komoto A., and Kanazawa K. 2005. Fucoxanthin induces cell cycle arrest at G0/G1 phase in human colon carcinoma cells through up-regulation of p21WAF1/Cip1. Biochimica et Biophysica Acta, 1726(3):328-335. PMID 16236452. Retrieved on January 24, 2007.
7. ^ Wu C.L., Zukerberg L.R., Ngwu C., Harlow E. and Lees J.A. 1995. In vivo association of E2F and DP family proteins. Molecular and Cellular Biology 15(5): 2536-2546. Entrez PubMed 7739537 Retrieved on January 24, 2007.
8. ^ a b Funk J.O., Waga S., Harry J.B., Espling E., Stillman B., and Galloway D.A. 1997. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Trends in Genetics, 13(12): 474.
9. ^ a b De Veylder L., Joubès J., and Inzé D. 2003. Plant cell cycle transitions. Current Opinion in Plant Biology. 6(6): 536-543.
10. ^ de Jager S.M., Maughan S., Dewitte W., Scofield S., and Murray J.A.H. 2005. The developmental context of cell-cycle control in plants. Seminars in Cell & Developmental Biology. 16(3): 385-396. PMID 15840447. Retrieved on January 24, 2007.
11. ^ a b Greenblatt R.J. 2005. Human papillomaviruses: Diseases, diagnosis, and a possible vaccine. Clinical Microbiology Newsletter, 27(18): 139-145. doi:10.1016/j.clinmicnews.2005.09.001. Retrieved on January 24, 2007.
12. ^ Sinal S.H. and Woods C.R. 2005. Human papillomavirus infections of the genital and respiratory tracts in young children. Seminars in Pediatric Infectious Diseases, 16(4): 306-316. PMID 16210110. Retrieved on January 24, 2007.
13. ^ Vietri M., Bianchi M., Ludlow J.W., Mittnacht S. and Villa-Moruzzi E. 2006. Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb. Cancer cell international, 6(3): 3 Entrez PubMed 16466572 Retrieved on January 24, 2007.
14. ^ Bartkova J., Grøn B., Dabelsteen E., and Bartek J. 2003. Cell-cycle regulatory proteins in human wound healing. Archives of Oral Biology, 48(2): 125-132. PMID 12642231. Retrieved on January 24, 2007.

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http://en.wikipedia.org/wiki/RB1

7.

Mdm2 is an important negative regulator of the p53 tumor suppressor.

It is the name of a gene as well as the protein encoded by that gene.

Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor suppressor and an inhibitor of p53 transcriptional activation.

Contents


* 1 Discovery and expression in tumor cells
* 2 Ubiquitination target: p53
* 3 E3 ligase activity
* 4 Structure/function details
* 5 Regulation
* 6 References
* 7 Further reading
* 8 External links

[edit] Discovery and expression in tumor cells

The murine double minute (mdm2) oncogene, which codes for the Mdm2 protein, was originally cloned, along with two other genes (mdm1 and mdm3) from the transformed mouse cell line 3T3-DM. Mdm2 overexpression, in cooperation with oncogenic Ras, promotes transformation of primary rodent fibroblasts, and mdm2 expression led to tumor formation in nude mice. The human homologue of this protein was later identified and is sometimes called Hdm2. Further supporting the role of mdm2 as an oncogene, several human tumor types have been shown to have increased levels of Mdm2, including soft tissue sarcomas and osteosarcomas as well as breast tumors. An additional Mdm2 family member, Mdm4 (also called MdmX), has been discovered and is also an important negative regulator of p53.

[edit] Ubiquitination target: p53

The key target of Mdm2 is the p53 tumor suppressor. Mdm2 has been identified as a p53 interacting protein that represses p53 transcriptional activity. Mdm2 achieves this repression by binding to and blocking the N-terminal trans-activation domain of p53.

Mdm2 is a p53 responsive gene—that is, its transcription can be activated by p53. Thus when p53 is stabilized, the transcription of Mdm2 is also induced, resulting in higher Mdm2 protein levels.

[edit] E3 ligase activity

Mdm2 also acts as an E3 ubiquitin ligase, targeting both itself and p53 for degradation by the proteasome (see also Ubiquitin). Several lysine residues in p53 C-terminus have been identified as the sites of ubiquitination, and it has been shown that p53 protein levels are downregulated by Mdm2 in a proteasome-dependent manner.

Mdm2 is capable of auto-polyubiquitination, and in complex with p300, a cooperating E3 ubiquitin ligase, is capable of polyubiquitinating p53.

In this manner, Mdm2 and p53 are the members of a negative feedback control loop that keeps the level of p53 low in the absence of p53-stabilizing signals. This loop can be interfered with by kinases and genes like p14arf when p53 activation signals, including DNA damage, are high.

[edit] Structure/function details

The full-length transcript of the mdm2 gene encodes a protein of 491 amino acids with a predicted molecular weight of 56kDa. This protein contains several conserved structural domains including an N-terminal p53 interaction domain, the structure of which has been solved using x-ray crystallography.

The Mdm2 protein also contains a central acidic domain (residues 230-300). The phosphorylation of residues within this domain appears to be important for regulation of Mdm2 function.

In addition, this region contains nuclear export and import signals that are essential for proper nuclear-cytoplasmic trafficking of Mdm2. Another conserved domain within the Mdm2 protein is a Zinc finger domain, the function of which is poorly understood.

[[[

A zinc finger is a large superfamily of protein domains that can bind to DNA. A zinc finger consists of two antiparallel β strands, and an α helix. The zinc ion is crucial for the stability of this domain type - in the absence of the metal ion the domain unfolds as it is too small to have a hydrophobic core.

Contents
[hide]

* 1 Classes
* 2 Structure
* 3 Proteins with Zinc finger
* 4 Binding specificity
* 5 See also
* 6 References
* 7 External links

[edit] Classes

One very well explored subset of zinc-fingers (the C2H2 class) comprises a pair of cysteine residues in the beta strands and two histidine residues in the alpha helix which are responsible for binding a zinc ion. The two other classes of zinc finger proteins are the C4 and C6 classes. Zinc fingers are important in regulation because when interacted with DNA and zinc ion, they provide a unique structural motif for DNA-binding proteins.

[edit] Structure

The structure of each individual finger is highly conserved and consists of about 30 amino acid residues, constructed as a ββα fold and held together by the zinc ion. The α-helix occurs at the C-terminal part of the finger, while the β-sheet occurs at the N-terminal part.

The consensus sequence of a single finger is: Cys-X2-4-Cys-X3-Phe-X5-Leu-X2-His-X3-His

[edit] Proteins with Zinc finger

Many transcription factors (such as Zif268), regulatory proteins, and other proteins that interact with DNA contain zinc fingers. These proteins typically interact with the major groove along the double helix of DNA in which case the zinc fingers are arranged around the DNA strand in such a way that the α-helix of each finger contacts the DNA, forming an almost continuous stretch of α-helices around the DNA molecule.

Some primary neuron-specific transcriptional regulator that may be involved in mediating early neural development are also zinc finger-based.

[edit] Binding specificity

The binding specificity for 3–4 base pairs is conferred by a short stretch of amino acid residues in the α-helix. The primary position of the amino acid residues within the α-helix interacting with the DNA are at positions -1, 3 and 6 relative to the first amino acid residue of the α-helix. Other amino acid positions can also influence binding specificity by assisting amino acid residues to bind a specific base or by contacting a fourth base in the opposite strand, causing target-site overlap.

[edit] See also

* Zinc finger inhibitor
* Steroid hormone receptor

[edit] References

Luscombe, Nicholas, et al (9 June 2000). "An overview of the structures of protein-DNA complexes". Genome Biology Review 1 (1): 4–5. doi:10.1186/gb-2000-1-1-reviews001.

Zinc finger inhibition is the process by which the synthesis of zinc fingers is blocked. Zinc finger inhibitors have been tested for their efficacy in treating AIDS and HIV. [at least treating what some think is AIDS or treating the signs of it, since nothing called HIV or AIDS has ever been isolated.]

]]]


Mdm2 also contains a C-terminal RING domain (amino acid resdiues 430-480), which contains a Cis3-His2-Cis3 consensus that coordinates two molecules of zinc. These residues are required for zinc binding, which is essential for proper folding of the RING domain. The RING domain of Mdm2 confers E3 ubiquitin ligase activity and is sufficient for E3 ligase activity in Mdm2 RING autoubiquitination. The RING domain of Mdm2 is unique in that it incorporates a conserved Walker A or P-loop motif characteristic of nucleotide binding proteins, as well as a nucleolar localization sequence. The RING domain also binds specifically to RNA, although the function of this is poorly understood.

[edit] Regulation

There are several known mechanisms for regulation of Mdm2.

One of these mechanisms is phosphorylation of the Mdm2 protein.

Mdm2 is phosphorylated at multiple sites in cells. Following DNA damage, phosphorylation of Mdm2 leads to changes in protein function and stabilization of p53.

Additionally, phosphorylation at certain residues within the central acidic domain of Mdm2 may stimulate its ability to target p53 for degradation.

The induction of the p14arf protein, the alternate reading frame product of the p16INK4a locus, is also a mechanism of negatively regulating the p53-Mdm2 interaction. p14arf directly interacts with Mdm2 and leads to up-regulation of p53 transcriptional response.

ARF sequesters Mdm2 in the nucleolus, resulting in inhibition of nuclear export and activation of p53, since nuclear export is essential for proper p53 degradation.

[edit] References

1. ^ Uhrinova S, Uhrin D, Powers H, et al (2005). "Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding". J. Mol. Biol. 350 (3): 587–98. doi:10.1016/j.jmb.2005.05.010. PMID 15953616.

[edit] Further reading

* Cahilly-Snyder, L., Yang-Feng, T., Francke, U., and George, D. L. (1987). Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somat Cell Mol Genet 13, 235-244.. Entrez PubMed 3474784
* Chen, J., Lin, J., and Levine, A. J. (1995). Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Mol Med 1, 142-152. Entrez PubMed 8529093
* Fang, S., Jensen, J. P., Ludwig, R. L., Vousden, K. H., and Weissman, A. M. (2000). Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J Biol Chem 275, 8945-8951. Entrez PubMed 10722742
* Freedman, D. A., Wu, L., and Levine, A. J. (1999). Functions of the MDM2 oncoprotein. Cell Mol Life Sci 55, 96-107. Entrez PubMed 10065155
* Hay, T. J., and Meek, D. W. (2000). Multiple sites of in vivo phosphorylation in the MDM2 oncoprotein cluster within two important functional domains. FEBS Lett 478, 183-186. Entrez PubMed 10922493
* Honda, R., Tanaka, H., and Yasuda, H. (1997). Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 420, 25-27. Entrez PubMed 9450543
* Honda, R., and Yasuda, H. (2000). Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase. Oncogene 19, 1473-1476. Entrez PubMed 10723139
* Kubbutat, M. H., Jones, S. N., and Vousden, K. H. (1997). Regulation of p53 stability by Mdm2. Nature 387, 299-303. Entrez PubMed 9153396
* Pavletich, N. P. (1996). Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science 274, 948-953. Entrez PubMed 8875929
* Meek, D. W., and Knippschild, U. (2003). Posttranslational modification of MDM2. Mol Cancer Res 1, 1017-1026. Entrez PubMed 14707285
* Midgley, C. A., Desterro, J. M., Saville, M. K., Howard, S., Sparks, A., Hay, R. T., and Lane, D. P. (2000). An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo. Oncogene 19, 2312-2323. Entrez PubMed 10822382
* Momand, J., Wu, H. H., and Dasgupta, G. (2000). MDM2--master regulator of the p53 tumor suppressor protein. Gene 242, 15-29. Entrez PubMed 10721693
* Momand, J., Zambetti, G. P., Olson, D. C., George, D., and Levine, A. J. (1992). The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69, 1237-1245. Entrez PubMed 1535557
* Shieh, S. Y., Ikeda, M., Taya, Y., and Prives, C. (1997). DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334. Entrez PubMed 9363941
* Tao, W., and Levine, A. J. (1999). P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Proc Natl Acad Sci U S A 96, 6937-6941. Entrez PubMed 10359817
* Tao, W., and Levine, A. J. (1999). Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53. Proc Natl Acad Sci U S A 96, 3077-3080. Entrez PubMed 10077639

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http://en.wikipedia.org/wiki/Mdm2


8.

Oleanolic acid is a naturally occurring triterpenoid, widely distributed in food and medicinal plants, related to betulinic acid.

It can be found in Phytolacca americana (American pokeweed), and Syzygium spp, garlic, etc.

It is relatively non-toxic, antitumor, and hepatoprotective, as well as exhibiting antiviral properties.[1]

Oleanolic acid was found to exhibit strong anti-HIV activity [Kishiwada 1998], the related compound betulinic acid was used to create the first commercial Maturation inhibitor drug.

It was first studied and isolated from several plants, including Rosa woodsii (leaves), Prosopis glandulosa (leaves and twigs), Phordendron juniperinum (whole plant), Syzygium claviflorum (leaves), Hyptis capitata (whole plant), and Ternstromia gymnanthera (aerial part).

Other Syzygium species including java apple (Syzygium samarangense), rose apples that contain it.

An extremely potent synthetic triterpenoid analogue of oleanolic acid was found in 2005, that are powerful inhibitors of cellular inflammatory processes.

They work by the induction by IFN- of inducible nitric oxide synthase (iNOS) and of cyclooxygenase 2 in mouse macrophages. They are extremely potent inducers of the phase 2 response (e.g., elevation of NADH-quinone oxidoreductase and heme oxygenase 1), which is a major protector of cells against oxidative and electrophile stress.[2]

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http://en.wikipedia.org/wiki/Oleanolic_acid

9.

Moronic acid is 3-oxoolean-18-en-28-oic acid, a natural triterpene.[1][2]

Moronic acid can be extracted from Rhus javanica, a sumac plant traditionally believed to hold medicinal applications.[2]

The molecule has also been extracted from Mistletoe (Phoradendron reichenbachianum).[3]

PA-457, a derivative of the related triterpenoid betulinic acid, was developed into an anti-HIV [sic] drug; however, moronic acid showed better antiviral profiles than PA-457, which has successfully completed a Phase IIa clinical trial.[4]

A particular moronic acid derivative showed potent anti-HIV [sic] activity with EC50 values of 0.0085 microM against NL4-3, 0.021 microM against PI-R (a multiple protease inhibitor resistant strain), and 0.13 microM against FHR-2 (an HIV strain resistant to PA-457). This derivative has become a new lead for clinical trials. It is also active against herpes simplex virus 1.[4]

[edit] References

1. ^ "Comparative Toxicogenomics Database: moronic acid".
2. ^ a b Kurokawa M, Basnet P, Ohsugi M, Hozumi T, Kadota S, Namba T, Kawana T, Shiraki K (Apr 1999). "Anti-herpes simplex virus activity of moronic acid purified from Rhus javanica in vitro and in vivo". The Journal of Pharmacology and Experimental Therapeutics. PMID 10086989.
3. ^ Rios MY, Salina D, Villarreal ML (Jul 2001). "Cytotoxic activity of moronic acid and identification of the new triterpene 3,4-seco-olean-18-ene-3,28-dioic acid from Phoradendron reichenbachianum". Planta Medica 67: 443. doi:10.1055/s-2001-15823. PMID 11488459.
4. ^ a b Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents. Yu D, Sakurai Y, Chen CH, Chang FR, Huang L, Kashiwada Y, Lee KH.


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http://en.wikipedia.org/wiki/Moronic_acid

10.

Terpenes are a large and varied class of hydrocarbons, produced primarily by a wide variety of plants, particularly conifers,[1] though also by some insects such as swallowtail butterflies, which emit terpenes from their osmeterium.

They are the major components of resin, and of turpentine produced from resin.

The name "terpene" is derived from the word "turpentine". In addition to their roles as end-products in many organisms, terpenes are major biosynthetic building blocks within nearly every living creature.

[Interesting ecological 'lock' against pollution, eh, that the end-products of living creatures here are the natural building blocks of future assembly for other living creatures...full circle, ecological modernization 'closed loop production cycles' in the natural ecology.]

Steroids, for example, are derivatives of the triterpene squalene.

When terpenes are modified chemically, such as by oxidation or rearrangement of the carbon skeleton, the resulting compounds are generally referred to as terpenoids.

Some authors will use the term terpene to include all terpenoids. Terpenoids are also known as Isoprenoids.

Terpenes and terpenoids are the primary constituents of the essential oils of many types of plants and flowers.

Essential oils are used widely as natural flavor additives for food, as fragrances in perfumery, and in traditional and alternative medicines such as aromatherapy.

Synthetic variations and derivatives of natural terpenes and terpenoids also greatly expand the variety of aromas used in perfumery and flavors used in food additives. Vitamin A is an example of a terpene.

Contents

* 1 Structure and biosynthesis
* 2 Types
* 3 Agri-chemical use
* 4 See also
* 5 References
* 6 External links

[edit] Structure and biosynthesis

Isoprene

Terpenes are derived biosynthetically from units of isoprene, which has the molecular formula C5H8.

The basic molecular formulae of terpenes are multiples of that, (C5H8)n where n is the number of linked isoprene units. This is called the isoprene rule or the C5 rule. The isoprene units may be linked together "head to tail" to form linear chains or they may be arranged to form rings.

One can consider the isoprene unit as one of nature's common building blocks.

Isoprene itself does not undergo the building process, but rather activated forms, isopentenyl pyrophosphate (IPP or also isopentenyl diphosphate) and dimethylallyl pyrophosphate (DMAPP or also dimethylallyl diphosphate), are the components in the biosynthetic pathway. IPP is formed from acetyl-CoA via the intermediacy of mevalonic acid in the HMG-CoA reductase pathway. An alternative, totally unrelated biosynthesis pathway of IPP is known in some bacterial groups and the plastids of plants, the so-called MEP(2-Methyl-D-erythritol-4-phosphate)-pathway, which is initiated from C5-sugars. In both pathways, IPP is isomerized to DMAPP by the enzyme isopentenyl pyrophosphate isomerase.

The
Dimethylallyl pyrophosphate

Isopentenyl pyrophosphate

As chains of isoprene units are built up, the resulting terpenes are classified sequentially by size as hemiterpenes, monoterpenes, sesquiterpenes, diterpenes, sesterterpenes, triterpenes, and tetraterpenes.

[edit] Types

Second or third instar caterpillar of Papilio glaucus emit terpenes from their osmeterium

Terpenes may be classified by the number of terpene units in the molecule; a prefix in the name indicates the number of terpene units needed to assemble the molecule.

A single terpene unit is formed from two molecules of isoprene, so that a monoterpene consists of one terpene but two isoprene units.

* Hemiterpenes consist of a single isoprene unit. Isoprene itself is considered the only hemiterpene, but oxygen-containing derivatives such as prenol and isovaleric acid are hemiterpenoids.

* Monoterpenes consist of two isoprene units and have the molecular formula C10H16. Examples of monoterpenes are: geraniol, limonene and terpineol.

* Sesquiterpenes consist of three isoprene units and have the molecular formula C15H24. Examples of sesquiterpenes are: farnesol. The sesqui- prefix means one and a half.

* Diterpenes are composed for four isoprene units and have the molecular formula C20H32. They derive from geranylgeranyl pyrophosphate. Examples of diterpenes are cafestol, kahweol, cembrene and taxadiene (precursor of taxol). Diterpenes also form the basis for biologically important compounds such as retinol, retinal, and phytol. They are known to be antimicrobial and antiinflammatory. The herb Sideritis contains diterpenes.

* Sesterterpenes, terpenes having 25 carbons and five isoprene units, are rare relative to the other sizes. The sester- prefix means half to three, i.e. two and a half.

* Triterpenes consist of six isoprene units and have the molecular formula C30H48. The linear triterpene squalene, the major constituent of shark liver oil, is derived from the reductive coupling of two molecules of farnesyl pyrophosphate. Squalene is then processed biosynthetically to generate either lanosterol or cycloartenol, the structural precursors to all the steroids.

* Tetraterpenes contain eight isoprene units and have the molecular formula C40H64. Biologically important tetraterpenes include the acyclic lycopene, the monocyclic gamma-carotene, and the bicyclic alpha- and beta-carotenes.

* Polyterpenes consist of long chains of many isoprene units. Natural rubber consists of polyisoprene in which the double bonds are cis. Some plants produce a polyisoprene with trans double bonds, known as gutta-percha.

[edit] Agri-chemical use

Research into terpenes has found that many of them possess qualities that make them ideal active ingredients as part of natural agricultural pesticides.

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http://en.wikipedia.org/wiki/Terpene

11.

While there is ample evidence to support the health benefits of diets rich in fruits, vegetables, legumes, whole grains and nuts, evidence that these effects are due to specific nutrients or phytochemicals is limited.[1]

The following is a list of phytochemicals present in commonly consumed foods.

Contents


* 1 Phenolic compounds
* 2 Terpenes (isoprenoids)
* 3 Betalains
* 4 Organosulfides
* 5 Indoles, glucosinolates
* 6 Protein inhibitors
* 7 Other organic acids
* 8 References

[edit] Phenolic compounds

* Monophenols
o Apiole – parsley.
o Carnosol – rosemary.
o Carvacrol – oregano, thyme.
o Dillapiole – dill.
o Rosemarinol – rosemary.
* Flavonoids (polyphenols) – red, blue, purple pigments.
o Flavonols
+ Quercetin – red and yellow onions, tea, wine, apples, cranberries, buckwheat, beans.
+ Gingerol – ginger.
+ Kaempferol – strawberries, gooseberries, cranberries, peas, brassicates, chives.
+ Myricetin – grapes, walnuts.
+ Resveratrol – grape skins and seeds, wine, nuts, peanuts.
+ Rutin – citrus fruits, buckwheat, parsley, tomato, apricot, rhubarb, tea.
+ Isorhamnetin
o Flavanones
+ Hesperidin – citrus fruits.
+ Naringenin – citrus fruits.
+ Silybin – blessed milk thistle.
+ Eriodictyol
o Flavones
+ Apigenin – chamomile, celery, parsley.
+ Tangeritin – tangerine and other citrus peels.
+ Luteolin
o Flavan-3-ols
+ Catechins – white tea, green tea, black tea, grapes, wine, apple juice, cocoa, lentils, black-eyed peas.
+ (+)-Catechin
+ (+)-Gallocatechin
+ (-)-Epicatechin
+ (-)-Epigallocatechin
+ (-)-Epigallocatechin gallate(EGCG)– green tea;
+ (-)-Epicatechin 3-gallate
+ Theaflavin – black tea;
+ Theaflavin-3-gallate – black tea;
+ Theaflavin-3'-gallate – black tea;
+ Theaflavin-3,3'-digallate – black tea;
+ Thearubigins
o Anthocyanins (flavonals) and Anthocyanidins – red wine, many red, purple or blue fruits and vegetables.
+ Pelargonidin – bilberry, raspberry, strawberry.
+ Peonidin – bilberry, blueberry, cherry, cranberry, peach.
+ Cyanidin – red apple & pear, bilberry, blackberry, blueberry, cherry, cranberry, peach, plum, hawthorn, loganberry, cocoa.
+ Delphinidin – bilberry, blueberry.
+ Malvidin – bilberry, blueberry.
+ Petunidin
o Isoflavones (phytoestrogens)
+ Daidzein (formononetin) – soy, alfalfa sprouts, red clover, chickpeas, peanuts, other legumes.
+ Genistein (biochanin A) – soy, alfalfa sprouts, red clover, chickpeas, peanuts, other legumes.
+ Glycitein – soy.
o Dihydroflavonols
o Chalcones
o Coumestans (phytoestrogens)
+ Coumestrol – red clover, alfalfa sprouts, soy, peas, brussels sprouts.
* Phenolic acids
o Ellagic acid – walnuts, strawberries, cranberries, blackberries, guava, grapes.
o Gallic acid – tea, mango, strawberries, rhubarb, soy.
o Salicylic acid – peppermint, licorice, peanut, wheat.
o Tannic acid – nettles, tea, berries.
o Vanillin – vanilla beans, cloves.
o Capsaicin – chilli peppers.
o Curcumin – turmeric, mustard. (Oxidizes to vanillin.)
* Hydroxycinnamic acids
o Caffeic acid – burdock, hawthorn, artichoke, pear, basil, thyme, oregano, apple.
o Chlorogenic acid – echinacea, strawberries, pineapple, coffee, sunflower, blueberries.
o Cinnamic acid – aloe.
o Ferulic acid – oats, rice, artichoke, orange, pineapple, apple, peanut.
o Coumarin – citrus fruits, maize.
* Lignans (phytoestrogens) – seeds (flax, sesame, pumpkin, sunflower, poppy), whole grains (rye, oats, barley), bran (wheat, oat, rye), fruits (particularly berries) and vegetables.[2]
o Silymarin – artichokes, milk thistle.
o Matairesinol – flax seed, sesame seed, rye bran and meal, oat bran, poppy seed, strawberries, blackcurrants, broccoli.
o Secoisolariciresinol – flax seeds, sunflower seeds, sesame seeds, pumpkin, strawberries, blueberries, cranberries, zucchini, blackcurrant, carrots.
o Pinoresinol and lariciresinol – [3] sesame seed, Brassica vegetables
* Tyrosol esters
o Tyrosol – olive oil
o Hydroxytyrosol – olive oil
o Oleocanthal – olive oil
o Oleuropein – olive oil

* Stilbenoids
o Resveratrol – grapes, peanuts;
o Pterostilbene – grapes, blueberries;
o Piceatannol – grapes

[edit] Terpenes (isoprenoids)

* Carotenoids (tetraterpenoids)
o Carotenes - orange pigments
+ α-Carotene – to vitamin A, in carrots, pumpkins, maize, tangerine, orange.
+ β-Carotene – to vitamin A, in dark, leafy greens and red, orange and yellow fruits and vegetables.
+ γ-Carotene
+ δ-Carotene
+ Lycopene – Vietnam Gac, tomatoes, grapefruit, watermelon, guava, apricots, carrots.
+ Neurosporene
+ Phytofluene – star fruit, sweet potato, orange.
+ Phytoene – sweet potato, orange.
o Xanthophylls - yellow pigments.
+ Canthaxanthin – paprika.
+ Cryptoxanthin – mango, tangerine, orange, papaya, peaches, avocado, pea, grapefruit, kiwi.
+ Zeaxanthin – wolfberry, spinach, kale, turnip greens, maize, eggs, red pepper, pumpkin, oranges.
+ Astaxanthin – microalge, yeast, krill, shrimp, salmon, lobsters, and some crabs
+ Lutein – spinach, turnip greens, romaine lettuce, eggs, red pepper, pumpkin, mango, papaya, oranges, kiwi, peaches, squash, legumes, brassicates, prunes, sweet potatoes, honeydew melon, rhubarb, plum, avocado, pear.
+ Rubixanthin – rose hips.

* Monoterpenes
o Limonene – oils of citrus, cherries, spearmint, dill, garlic, celery, maize, rosemary, ginger, basil.
o Perillyl alcohol – citrus oils, caraway, mints.
* Saponins – soybeans, beans, other legumes, maize, alfalfa.
* Lipids
o Phytosterols – almonds, cashews, peanuts, sesame seeds, sunflower seeds, whole wheat, maize, soybeans, many vegetable oils.
+ Campesterol - buckwheat.
+ beta Sitosterol – avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat.
+ gamma sitosterol
+ Stigmasterol – buckwheat.
o Tocopherols (vitamin E)
o omega-3,6,9 fatty acids – dark-green leafy vegetables, grains, legumes, nuts.
+ gamma-linolenic acid – evening primrose, borage, blackcurrant.

* Triterpenoid
o Oleanolic acid - American pokeweed, honey mesquite, garlic, java apple, cloves, and many other Syzygium species.
o Ursolic acid - apples, basil, bilberries, cranberries, elder flower, peppermint, lavender, oregano, thyme, hawthorn, prunes.
o Betulinic acid - Ber tree, white birch, tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas a member of the persimmon family, Tetracera boiviniana, the jambul (Syzygium formosanum), and many other Syzygium species.
o Moronic acid - Rhus javanica (a sumac), mistletoe

[edit] Betalains

* Betalains
o Betacyanins
+ betanin - beets
+ isobetanin - beets
+ probetanin - beets
+ neobetanin - beets
o Betaxanthins (non glycosidic versions)
+ Indicaxanthin - beets, sicilian prickly pear
+ Vulgaxanthin - beets

[edit] Organosulfides

* Dithiolthiones (isothiocyanates)
o Sulphoraphane – Brassicates.
* Thiosulphonates (allium compounds)
o Allyl methyl trisulfide – garlic, onions, leeks, chives, shallots.
o Diallyl sulfide – garlic, onions, leeks, chives, shallots.

[edit] Indoles, glucosinolates

* Indole-3-carbinol – cabbage, kale, brussels sprouts, rutabaga, mustard greens.
* sulforaphane - broccoli family
* 3,3'-Diindolylmethane or DIM - broccoli family
* Sinigrin - broccoli family
* Allicin - garlic
* Alliin - garlic
* Allyl isothiocyanate - horseradish, mustard, wasabi
* Piperine - black pepper
* Syn-propanethial-S-oxide - cut onions.

[edit] Protein inhibitors

* Protease inhibitors – soy, seeds, legumes, potatoes, eggs, cereals.

[edit] Other organic acids

* Oxalic acid – orange, spinach, rhubarb, tea and coffee, banana, ginger, almond, sweet potato, bell pepper.
* Phytic acid (inositol hexaphosphate) – cereals, nuts, sesame seeds, soybeans, wheat, pumpkin, beans, almonds.
* Tartaric acid – apricots, apples, sunflower, avocado, grapes.
* Anacardic acid - cashews, mangoes.

[edit] References

1. ^ Linus Pauling Institute at Oregon State University
2. ^ Linus Pauling Institute at Oregon State University
3. ^ Lignan contents of Dutch plant foods: a database i...[Br J Nutr. 2005] - PubMed Result

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http://en.wikipedia.org/wiki/List_of_phytochemicals_and_foods_in_which_they_are_prominent

Mark said...

Dr. Zorba Hates Your Liver
By Alan Graham
With Alfred Lehmberg
AlienView.net
10-2-8

See, NPR's Dr. Zorba Pastuer, once again, puts his "ignorant hatred" on display via his syndicated radio show! It's either that, reader, or he just refuses to say anything good about alternative therapies including natural herbs or supplements.

Though, you would think he should recommend, when appropriate, foods that might help - especially when specifically asked, eh?

One female caller, for example, wanted to know what supplements and foods a person should consume to protect their Liver. As usual, Zorba's answer was beyond inadequate... he essentially said there was nothing he knew of to help the liver except "don't drink alcohol in excess" and "don't get fat"... gee, thanks for less than nothing, Docca Z-man!

I'm not surprised he didn't mention Milk-Thistle or any of the other very well known and very valid liver supplements used for thousands of years, but couldn't he at least tell the lady about foods that help and hurt the liver; after all, he claims to be a nutritional expert. He's written a book, anyway.

Toward the end I will list some other good liver-supp's like the Milk-Thistle mentioned above. Milk-Thistle, while we're here, is nothing less than extraordinary, considering it can detox your liver while it stimulates the production of new liver cells (for all you ex-drinkers, like me) and about a dozen other things to include being a powerful, immune-enhancing Cancer-fighter.

Silymarin, the group of active ingredients in Milk-Thistle, has been used by Medical Doctors in Germany for almost 60 years to treat all forms of liver disease like hepatitis & cirrhosis. Those Teutons drink a lot of beer & wine. Gee, Zorba lectures all over the world to other MD's... don't they share info? Does Zorba hear a different drummer? Uh, like Merck, you think?

FOODS to eat and foods to avoid:

EAT :

(A).. Bitter Greens - like Parsley, Cilantro, Endive, Arugula, Watercress and Dandelion, these are powerful, "Liver De-Tox Greens." These astringent foods help protect the liver from the ravages of smoking, drinking, and toxic pollution while they clean and revitalize the liver and gall bladder.

(B).. Food Fats and Oils - In my humble opinion there are only 4 (well, maybe 5) acceptable FOOD-Fats! These love your liver:

1). Extra-Virgin Olive Oil (EVO) - a "true" MONO-oil at 76% Mono. Use everywhere. Don't believe the silly theory that you can't bake with olive oil because of the "fruitiness"...not so, Olive oil makes baked goods taste rich, not fruity.

You see Olive Oil is "magical"! On foods and in dishes where you want the bold flavor, it is there! Though, in dishes where you don't want that exotic taste, it somehow "knows" to disappear. Weird! Bottom line: use EVO for EVERYTHING.
2). Macadamia Nut Oil - the other "true" MONO-oil at the HIGHEST % Mono at 80%. Also, Macadamia Nut Oil has the highest Smoke-Point of any UNrefined oil, at close to 400F! This is probably the best food oil in the world... but it is considerably more expensive than Olive Oil and, to be honest, it is a very bland tasting oil.

Believe me; you would never see Don Corleone "dipping" chunks of Italian bread in a dish of Macadamia Nut oil and eating it with nothing else... like he would certainly do with rich, "fruity", Extra-Virgin Olive Oil, with its "other-worldly" taste.

Your liver loves olive oil... in fact, the most popular liver cleanse out there is done with olive oil and lemon juice... there are several variations on the web... pick the easiest one.


3). Hexane-Free, unrefined Coconut Oil - is especially loved by your liver because of the wonderful and unique solid SatFat, MCT's, (medium-chain-triglycerides or medium-chain-fatty-acids) making up Coconut Oil also make it solid below 76 degrees Fahrenheit!

FYI : This means in the tropics (where it comes from) and in YOUR BODY it is Liquid... for all you Dieticians and other assorted Bone-Heads who refer to it as a "solid Saturated Fat," with a self-righteous smirk, as if describing monkey dung. You're wrong. Step off.

See, MCT's ARE singularly unique! Consider, LCFA's, (long-chain-Fatty-acids) found in animal satfat and food oils, require Liver-Enzymes to begin to digest these longer chains! Conversely, to digest the shorter MCT's or MCFA's one only needs saliva and stomach acid! This is a really big deal!
You see, liver-Enzymes otherwise required for digestion of long chain fats may be in short supply. These are conserved. Also, even if these enzymes are in abundance, the Long-Chainedprocess is very slow compared to the Medium-Chained, metabolic "speed-racer" Fatty-Acids of coconut oil!

This "speed" is why Coconut oil MCT's are in EVERY baby formula on the shelf, actually, and VERY high in Mother's Milk! See, babies have underdeveloped "Desaturase Enzyme Systems" so they cannot readily digest LCFA's... but MCT's easily zip straight through to the cell's Energy-Center, the Mitochondria, providing the instant energy and heat for babies to develop rapidly.

This is also why it can help adults lose weight... it's called "Thermogenesis." Eating solid SatFat that is good for your heart & to lose weight ...who would'a thunk it? Clearly not the Zorbster!

4). Real Butter - is good for you, as opposed to Margarine, which is pHVO (partially Hydrogenated Vegetable Oil) and is a nutritional abomination of the highest order.

Go to France. By law, the butter in France must meet a very high percentage of butter-fat... none higher in the world! The lowest they allow is higher than our highest! It's the law!
Return to the US. With regard to life-span, we in the heartland are down around #19 or #20 in the world... and we've used margarine and put pHVO in every processed food we could,avoiding butter!
The French are #2 or #3...and they put real, high butter-fat butter... on EVERYTHING. Don't be surprised to see it on watermelon over there!

I've been to France several times - I think they all start smoking at 13 (that's a guess) and they will "Party" till 4 AM, even during the week... so with the #2 life-span in the world, I would submit that the French -using gobs of butter, olive oil and red wine- can even trump smoking and "party-till-you-puke" decadence! I want that for America!
Remaining. It is puzzling... at least! Or not!

See, the lesson here is *UNDAMAGED* Solid SatFat is good for you and is critical for dozens of bodily functions AND it does not cause Heart Disease - no more than the Inuit people's diet of blubber (solid SatFat) causes Heart Disease... they out-live everyone... ...and with the lowest incidence of Heart and Vascular disease on the planet? Yes!
Too, they appear to be very nearly immune to MS and other autoimmune diseases, forgetting all that "Complex" Omega-3 keeps them "Frisky" and "Rubbing-Noses" right to "The End"...no need for Viagra-vated genitals in the old igloo, boy! "Viagra-vated genitals"... C'mon, I don't care who you are, that's funny.

No Folks, the "Fats" that stop your heart and erode your life quality are oxidized -even though it's "fresh" from the store- Poly-Unsat "Vegetable Oils"! These are oils like Soy andCorn, and TransFat from Hydrogenated Poly-Unsat Vegetable Oils turned into Manmade "Fake" SatFat like Crisco and Margarine. Both of the preceding are found in virtually all processed foods and deep-fat fryers in this country. Golden Deep-Fat death.

5). Technically, there is a 5th category - Flaxseed and Hempseed are "Medicinal-Oils" but if you're careful they can be used as "Food-Oils" on anything cold, like salad. Don't leave eitherexposed to air any longer than you have to! The Omega-6 (GLA) and the Omega-3 (ALA) will oxidize... rapidly!

(C).. Cruciferous Veggies - like Broccoli, Cabbage, Cauliflower, Brussels' Sprouts and Bok Choi are the other hi-fiber, very healthful, vegetables for the liver... they have a particularly arcane and potent anti-oxidant which can help protect you from cancer... among other diseases.

TRIVIA? Cruciferous comes from the word Crucifix, because the little flower on the plant is shaped like a Cross.

Even though daily eating large amounts of raw Bitter Greens, Cruciferous Veggies and Veggies in general, is very healthful, it is also very difficult because most people don't like raw veggies unless they are covered with some toxic crap (commercial salad dressings) to hide the taste...

..."So Please", let me teach you how to make a "Liver and Heart Healthy Vinaigrette with Avocado" that can make even beets palatable - yeah, I know it sounds like a lie, because as we all know, humans don't actually eat beets, but it is true...yeah, Beets or anything for that matter.

FYI - On the other hand, supplemental Beet-Root in capsules happens to be great for your Liver. Of course beets have several phyto-chemicals (same as beet-root) that are also great for your liver - if humans only ate beets.

"SUPER-DUPER SALAD DRESSING": Olive Oil Vinaigrette with Avocado - the avocado is optional, of course but it is unreal what avocado does when you grind or blend it into the Vinaigrette below!

1. Red Wine Vinegar. Balsamic Vinegar tastes the best but it is pretty high in sugar. If you are a slim, non-diabetic, active person, then by all means throw some Balsamic in with the other sour stuff.

2. Lemon Juice ...fresh is best. By using some Lemon juice (Alkaline-forming food) instead of only Vinegar (mildly Acid-forming food) it makes the dressing pH a little more Alkaline...plus it has this great synergy with the blended Avocado. However, I have found that too much lemon can be a little "over-powering."

3. Extra Virgin Olive Oil (or the other Mono-Oil, Macadamia Nut Oil) ...Here's where my dressing is different. Many people, like the gastronomically snooty French, think there is a "Law" that Vinaigrettes MUST be at an Oil to Sour ratio of 2 to 1; however, I reverse that and use a ratio of 1 to 2... so, it is mostly lemon and vinegar. This means you need to use a lot of Stevia or Xylitol to cut the "Sour-stuff," but that's fine... just NEVER use sugar.

The beauty of making your own dressing is you can try different Oil to Vinegar Ratios. Yes, the Olive Oil is heart healthy, but why consume more of it than you need to. Still, if you're French and don't want to be fined by the SP's (Social Police), then by all means, use a 2 to 1 ratio.

4. Ripe Avocado: Mix in blender with other ingredients until it is thick enough to nicely coat Veggies... I have a tendency to throw in too much Avocado so it gets TOO thick.

5. A little bit of Sun Dried Sea Salt. Don't believe the "No Salt, Low Salt" Crap that "doctors" and dieticians perpetuate - you need a moderate amount of salt to make the stomach acid required to digest food! Please only use Sun-dried or Himalayan Sea Salt! The Salt must be pink, grey or off-white... NEVER pure white (indicates no Trace Minerals). Grocery stores sell the processed "Sea Salt" with NO trace minerals.

6 Coconut Oil (Optional) - Use just a little to give it a very mild coconut taste that is very synergistic with the Avocado and lemon.

Believe me, you will be amazed because the blended Avocado in the Vinaigrette creates a kind of "Green-Goddess" dressing making all those toxic store-bought "Green" dressings taste like green slime... which, of course, they are.

FYI - they are "slime" (even Paul Newman's Own, may he rest in peace) because they all use oxidized POLY-unsat Oil like Soy or Corn instead of MONO-unsat Oil like Extra Virgin Olive Oil. Mr. Newman deserves better than that.

Back to bad salad dressing, sometimes a front label might say "Olive Oil" dressing but when you turn it over and read the "Supp' Fact's" it will likely be one of the following :

(a). It only has about 10% or 20% Olive Oil and 80% or 90% Canola "Crap"...uh, I mean oil. The ubiquitous "Subway" franchise uses one of these 10% "olive oils" and readily refers to it as "OLIVE OIL"...tsk, tsk. The girl should say "Sir, do you want some 1/10th Olive oil, Oil?"

(b). Or if by some slim chance it actually has a significant amount of olive oil (like maybe 50%), it will be about as Extra Virgin as Paris Hilton... the oil will not be a dark vibrant green, like from the first pressing... because with subsequent pressings the oxidation increases and it will become a dull, lackluster blondish-yellow color, like its been around the block, a time or two...sort of like the Hilton chick? No judgments, just observations. I digress.

FOODS TO AVOID :

(1).. Margarine, P'nut Butter, Baked Goods or any other processed food with TransFat from pHVO (partially Hydrogenated Vegetable Oil)... even if the label SCREAMS "ZERO TransFat". Natural P'Nut Butter, of course, where the oil floats to the top, is OK.

You MUST always look in the "Ingredient Section" for pHVO (partially Hydrogenated Vegetable Oil). A product can have 1/2 gram or less of TransFat/pHVO per serving and still call itself "ZERO TransFat."

See, things like Margarine and P'nut Butter can have small servings where that 1/2 gram of TransFat looms large... but still say "ZERO TransFat" in BIG letters on the front... only to list pHVO or HVO in very fine print on the back! People NEVER make the connection that the "partially Hydrogenated Vegetable Oil" molecule, IS the TransFat molecule. So if it has pHVO in the ingredients then it CANNOT BE ZERO TRANSFAT. How is this not a lie by any other name, reader?

We know transFat from pHVO is a twisted and toxic molecule readily if errantly incorporated into the cell-wall of every cell in your body, causing disease and aging... plus your liver finds pHVO particularly vile and damaging! HVO is found in virtually every commercially processed food where you might find fats or oils... and some places you wouldn't expect to find a toxic, manmade Fat, like in "FlintStones" Children's Vitamins. Is nothing sacred?

The FDA has actually tried for decades to hide the fact that TransFat was in almost all our processed foods while most of the rest of the "1st World" countries had banned or voluntarily stopped using pHVO. Apparently, the Leaders at the FDA were psychologically abused as children and not breast fed.

This evil vegetable shortening (like Crisco) really came to the fore after WW-2, as a cheap way to feed the "masses" of the "Baby-Boom", utilizing our multi-purposeful, resource from the vast U.S. open plains, Corn and Corn Oil.

This PolyUnsaturated Corn Oil, through Hydrogenation, was cheaply converted to a toxic, solid, vegetable shortening (Man-made Saturated Fat) that your liver never encountered in a million of years of human evolution, yet in the 1940's became the ubiquitous "Oleo-Margarine."

This is also when a long list of diseases appeared that had never been heard of or were virtually unheard of... like Fibromyalgia or children with "Adult"-onset-diabetes".

When I was a little boy, not only did my grandmother put down her burdensome butter-churn but she would get misty-eyed when telling me that it was a miracle how us poor people were so blessed to have a cheap, heart-healthy "butter" made from vegetable oil... praise the Lord for Oleo!

Folks! The twisted, perverted Hydrogenated vegetable oil molecule does not do one good thing... it contributes adversely to EVERY disease and defines the aggregate unhealthful!
So why do all those Captains of Industry (who also weren't Breast-Fed) love pHVO? Well, it has an extremely long shelf-life so Mrs. Cartman can buy "Snacky-Cakes" and "Cheezy-Poofs" in bulk for her "big-boned" lad Eric, and our psychopathic "Cap's of Ind" won't have to pay for spoilage of "goods" unsold!

The horror, reader. For years Dr. Zorba has encouraged the use of margarine, so he must not understand the dangers of transfat... or chooses to ignore them. I vote for the latter. As a Doctor he has to know.

I recall during one show, Zorba's sidekick, Tom Clark, ask "Z" if a person could substitute butter for margarine in a recipe they were going through (they do one recipe every show) and Zorba YELLED (I'm not exaggerating...I jumped)...an emphatic, booming...NO !! It was about one octave below an SS dude screaming "NO, you Swinehund!" Suspicious ignorance at high volume... always a tell of the canted ideologue, eh?

The reason I even mention this seemingly insignificant event is, think about it... have you ever seen a cooking show or can you even imagine a person on a cooking show, asking if they could substitute butter for margarine, where the cook yells "NO" like a Nazi rabble-rouser... in fact, what does the cook say, in a nice calm voice, in real life or in your imagination... they ALWAYS say "Why yes, of course...You can substitute virtually ANYTHING for ANYTHING... that is the beauty of creative cooking."

But no, not in Zorba's World... and he will react strangely aggressive if you even hint at trying to replace a Man-Made, toxic Faux-Fat (margarine) with a natural Real-Fat (butter), which humans have consumed in relative safety for a million years... in one or the other of many forms of *Undamaged* Saturated Fat.

(2).. All "POLY" unsaturated food oil (like Soy, Corn, Canola, Safflower, Sunflower, Cottonseed, Grape seed, Peanut and more).

POLY-Oils FYI: Are rancid and toxic when "fresh from the store," remember, but you can't smell the rancidity because the oil is RBDed (refined, bleached, deodorized) at extremely high heat to destroy the odor... but the RBDing can't do a darn thing to lower the toxicity of the already oxidized oil! The resulting free-radicals attack your Liver, Heart, and Joints... so Dieticians LIE when they tell you that grocery store Vegetable Oil (usually Soy or Corn) is heart healthy.

(a).. Canola Oil - Dr. Zorba, et al, are always saying that Canola Oil is a heart-healthy, MONO-unsat Oil...(here it comes...), "Just like Olive Oil." Let me sound off with a "NO" of my own! See, you nutritional geniuses can keep on calling it a Mono-oil just because at 56% Mono, you have those pesky mathematics on your side, but to say it is just like Olive Oil is a gross misrepresentation! Here's why:

All edible oils will always have 3 types of FA's (Fatty-Acids) - Mono-Unsat, Poly-Unsat and solid SatFat but these fats at wildly different ratios! It is those ratios that mean EVERYTHING. Also it is the "Poly-Unsat" that goes rancid easily due to the heat of pressing... NOT the Mono or SatFat.

OK, so Olive Oil, coming from a soft fruit, is one of the reasons it does not require RBDing due to lower pressing temps, but the primary reason is because Olive Oil has a negligible percentage of Poly-oil (remember it's the poly that will easily go rancid) at only 8% Poly. See, because of the large 76% Mono and the fairly large SatFat at 16%,(a good thing) this means there's not room left over for much Poly... so 8% poly means no need for oil poisoning RBD processes!

Conversely, Canola or Rapeseed Oils, coming from a hard seed, do require RBDing due to higher pressing temps promoting spoilage, but primarily because it has a large % of Poly-oil (which will go rancid) at a significant 35%! See, the low 56% Mono and a low SatFat (a bad thing that it's low) leaves lots of space to be filled by Poly - hence the 35% poly will get you RBDed!

So, technically, you idiots performing such can continue to call canola oil a "mono-oil"... but don't you dare, then, tack on the stupid line, "and it's just like olive oil." The 56% Mono portion cannot undo the damage done by the rancid 35% Poly portion... so stop being a Bone-Head and start calling it a Poly-Oil, because it's the Poly part that is slowly killing you!

Oh yeah - the 8% Omega-3 that the "Liars" say is in Canola, well, it's in there... BUT it is an extremely sensitive Poly-Oil, remember, prone to ready spoilage, so that 8% of the 35% poly total is the FIRST fatty-acid to go rancid at pressing. In fact, that 8% will go rancid 6 or 8 times faster than the 27% of remaining poly oil... which will go rancid, too, just a littleslower.

SO LISTEN UP - to get non-oxidized Omega-3 Oil from a seed it must be pressed with added expensive REFRIGERATION... just like with "Medicinal Oils" such as Flaxseed Oil or Black Currant Seed Oil, and then refrigerated after opening. Toxic grocery store Canola Oil hasn't seen any refrigeration lately... Canola Oil is quality of life destroying Crap, people!

As promised at the top of this paper, some Liver Supplements:

1).. NAC (N-Acetyl-Cysteine) - dirt cheap powerful liver antioxidant but most importantly is the precursor to the # 1, hands-down, most valuable antioxidant that we produce: Glutathione (also called GSH). We make less GSH as we get older but taking supplemental GSH is not very effective ...so take the precursor instead - at least 600mg of NAC w/o food but please always take 1000mg of Vit.C with it. NAC is cheap but GSH... not so cheap.

The largest store of GSH is in the liver where, on the cellular level, it removes toxins like mercury, lead and even that oxidized Canola Oil you wrongfully ate.

2).. TMG (Trimethylglycine) - also dirt cheap but powerful liver Supplement that protects the liver from toxins, helps process fats, and SO much more. Also, along with folic acid, B-6 and B-12, TMG protects your heart from Homocysteine damage that is the real reason for the inflammation leading to most heart disease and blocked arteries... so STOP blaming too much cholesterol! If it's too high, it is because the cholesterol is responding to the inflamed artery, not because you eat high cholesterol foods.

3).. SAMe - NOT dirt cheap, so if money is tight, forget about SAMe. If money is not a problem then by all means take advantage of SAMe's Multi-Effects, like Liver protection, Joint and Cartilage repair, production of Neurotransmitters (emotional stability) and it also helps increase GSH. A 30 day supply is about $20 to $25.

OK, that's it...I hope you can now begin to appreciate the depth of Dr. Zorba's incompetence! Actually this is pretty minor in comparison to his many other, less than brilliant, observations. One day I plan on writing a book called "There's NO Omega-3 in Cod-Liver Oil" hi-lighting Dr. Z's on-air comments, see, actually there is about 220mg of Omega-3 in every gram of CLO.

Dr. Zorba? You have your own nation wide radio show, teach in Med schools, and travel the world lecturing doctors from other countries, so here's a bit of advice: if ever lecturing in Iceland or Norway, don't say there's no Omega-3 in Cod Liver Oil, Ok? The Icelanders and Norwegians will think you are a nose-bubbling idiot...
Write as you like -- <>alan068@centurytel.net

Until next time, well be.

---
http://www.rense.com/general83/dwrs2.htm

Mark said...

Cats and dogs cut their owners' cancer risk by a third, researchers say

By Jenny Hope
Last updated at 8:35 PM on 08th October 2008

* Comments (3)

Cat woman

Pet lovers are a third less likely to develop non-Hodgkin's lymphoma, a cancer of the lymphatic system

Owning a pet can reduce the chances of developing a form of cancer by nearly a third, researchers claim.

Animal lovers were much less likely to develop non-Hodgkin's lymphoma, a cancer of the lymphatic system that affects around 9,000 Britons a year.

Scientists at the University of California, San Francisco, and Stanford University, also in California, who carried out the study believe pets help protect against cancer by boosting the immune system.

Previous studies have shown children who have pets take fewer sick days off school because they are more resistant to infections.

Some research even suggests toddlers who grow up around cats or dogs are less likely to suffer allergies or asthma.

Non-Hodgkin's Lymphoma, or NHL, affects the lymphatic system, a network of vessels and glands that transports infection-fighting white blood cells round the body.

Cases of NHL rise with age. The average age of newly-diagnosed sufferers is 65, and the most aggressive form of NHL can be fatal.

The numbers affected in the UK have been steadily rising at around four per cent a year for the last 50 years. Experts fear if the trend continues, NHL will be as common as breast or lung cancer by 2025.

Although the exact cause of the increase remains a mystery, one theory is that improved hygiene and sterile living conditions may be to blame.

Recent evidence suggests exposure to allergens and toxins in the environment may actually help to protect the body against certain types of cancer.

In the latest investigation, researchers at the University of California San Francisco and Stanford University, also in California, studied more than 4,000 patients to see if owning a pet slashed their chances of getting cancer.

Just under 1,600 of the volunteers had developed NHL, while the remaining 2,500 were free of the disease.

The results showed pet owners were almost 30 per cent less likely to have cancer than those who had never kept animals.

The longer the family had kept pets, the greater the protection against the disease, the study found.

In a report , published in the journal Cancer Epidemiology, Biomarkers and Prevention, the researchers said: 'This large study provides support for a decreased risk between pet ownership and non-Hodgkin's Lymphoma. And it's possible this is related to altered immune function.'

Dr Jodie Moffat, health information officer at Cancer Research UK said: 'This study presents some evidence that owning a pet may reduce the risk of Non-Hodgkin’s Lymphoma. However much more research is needed to provide a conclusive link.

'Scientists around the world are trying to find out what causes Non-Hodgkin’s Lymphoma and what affects a person’s chances of developing the disease, but there is still a lot to learn.'

---
http://www.dailymail.co.uk/health/article-1073930/Cats-dogs-cut-owners-cancer-risk-researchers-say.html

Mark said...

Natural Notes on Health
by GayleEversole
leaflady@leaflady.org

Natural notes on health--Milk Thistle [Helpful to Optimizing Liver Function]

-------------------

Silymarin prevents free radical damage to the liver by acting as an antioxidant.

In research Silymarin has been found to be at least 10 times more potent in antioxidant activity than vitamin E.


-------------------


Your liver plays a major role in health because of the hundreds of things it does in and for your body. The liver helps with digestion because it produces bile to break down fat, while it helps metabolize carbohydrates and proteins. It creates important nutrients and can store them for years, and after a meal, the liver converts amino acids to glucose, proteins, or urea.

Your liver produces albumin to help with water balance, proteins crucial to the immune system, coagulation factors and globin for hemoglobin, which carries oxygen in the blood. The liver also produces cholesterol.

As a filter, your liver works hard to break down from food additives, alcohol, pollution, organophosphates, pharmaceuticals and other unfriendly substances that constantly bombard us.

To serve as a liver helper in today’s toxic world we can rely on Milk Thistle.

Milk Thistle has been used for liver problems for over 2,000 years, and that’s why it is the liver-protecting herb of choice. In ancient Rome, Pliny suggested that it carries off bile. English herbalist Culpepper suggested it was good for jaundice and for removing liver obstructions.

All parts of the milk thistle are said to be edible, and has long been used for food in the countries surrounding the Mediterranean. Young leaves can be trimmed of prickles and added to salads or steamed for a vegetable. They taste a little bitter and astringent and sort of get gummy as you chew.

The roots can be prepared and cooked like salsify or eaten raw. Young flower buds can be steamed and eaten like those of the globe artichoke, a close relative.

Like many members of the daisy family, the scorched roots and seeds of milk thistle have been used as a coffee substitute, the seed cake cattle fodder, and the seed oil for food or lubrication.

Milk thistle has been used for centuries to help support the liver and gall bladder. A key substance found in the seeds is called Silymarin which is a “group of flavonoids that is beneficial to the liver’s ability to effectively work with a myriad of impurities. Flavonoids are antioxidants.

Silymarin prevents free radical damage to the liver by acting as an antioxidant.

In research Silymarin has been found to be at least 10 times more potent in antioxidant activity than vitamin E.


Using properly prepared and high quality Milk thistle products you find it is helpful for preventing and eliminating gall stones; reducing cholesterol levels while improving the “good” kind; in cirrhosis and psoriasis; for hepatitis, diabetes, fatty liver and chemical exposure. Milk thistle is a good companion when you are getting chemo or taking a wide array of prescription drugs.

Milk thistle is believed to possess very little toxicity. Animal studies have not shown any negative effects even when high doses were administered over a long period of time. There is a low incidence of side effects, limited mainly to mild gastrointestinal disturbance.

Used extensively as a food, Milk thistle is believed to be safe for pregnant or nursing women. However, safety in young children, pregnant or nursing women, and individuals with severe renal disease has not been formally established.

No drug interactions are known. However, one report has noted that silybinin (a constituent of silymarin) can inhibit a bacterial enzyme called beta-glucuronidase, which plays a role in the activity of certain drugs, such as oral contraceptives. This could reduce their effectiveness.

The milk thistle is part of one of the largest plant families, the Asteraceae, or Compositae. This family includes everything from lettuce to sunflowers. People with allergy to members of this family (Daisy) are cautioned in its use.

For medicinal purposes are liquid extracts and capsules standardized at 80 percent silymarin. The recommended average daily dose is 200 to 400 milligrams. In some instances, mainly in Europe, intravenous silymarin is used.

This is part of the October 2, 2008 online edition of The Latah Eagle.

---
http://www.lataheagle.com/full.php?sid=4461&current_edition=2008-10-02

Mark said...

Cancer Cured For Good

By Bill Sardi and Timothy Hubbell
October 2008


It works 100% of the time to eradicate cancer completely, and cancer does not recur even years later. That is how researchers describe the most convincing cancer cure ever announced.

The weekly injection of just 100 billionths of a gram of a harmless glyco-protein (a naturally-produced molecule with a sugar component and a protein component) activates the human immune system and cures cancer for good, according to human studies among breast cancer and colon cancer patients, producing complete remissions lasting 4 and 7 years respectively.

This glyco-protein cure is totally without side effect but currently goes unused by cancer doctors.

Normal Gc protein (also called Vitamin-D binding protein) , an abundant glyco-protein found in human blood serum, becomes the molecular switch to activate macrophages when it is converted to its active form, called Gc macrophage activating factor (Gc-MAF).

Gc protein is normally activated by conversion to Gc-MAF with the help of the B and T cells (bone marrow-made and thymus gland-made white blood cells).

But, as researchers explain it themselves, cancer cells secrete an enzyme known as alpha-N-acetylgalactosaminidase (also called Nagalase) that completely blocks conversion of Gc protein to Gc-MAF, preventing tumor-cell killing by the macrophages.

This is the way cancer cells escape detection and destruction, by disengaging the human immune system.

This also leaves cancer patients prone to infections and many then succumb to pneumonia or other infections.

The once-weekly injection of minute amounts of Gc-MAF, just 100 nanograms (billionths of a gram), activates macrophages and allows the immune system to pursue cancer cells with vigor, sufficient to produce total long-term cures in humans.

Nobuto Yamamoto, director of the Division of Cancer Immunology and Molecular Biology, Socrates Institute for Therapeutic Immunology, Philadelphia, Pennsylvania, says this is “probably the most potent macrophage activating factor ever discovered.”


A MACROPHAGE OVERCOMES AND EATS A CANCER CELL.
FROM THE UPJOHN COMPANY, THE IMMUNE SYSTEM

Once a sufficient number of activated macrophages are produced, another Gc-MAF injection is not needed for a week because macrophages have a half-life of about six days. After 16-22 weekly doses of Gc-MAF the amount of Nagalase enzyme fell to levels found in healthy people, which serves as evidence tumors have been completely eliminated. The treatment was fool-proof - - - it worked in 100% of 16 breast cancer patients and there were no recurrent tumors over a period of 4 years, says a report in the January 15 issue of the International Journal of Cancer. [International Journal Cancer.2008 January15; 122(2):461-7]

In another startling follow-up report by Dr. Yamamoto and colleagues, published in the upcoming July issue of Cancer Immunology Immunotherapy, Gc-MAF therapy totally abolished tumors in 8 colon cancer patients who had already undergone surgery but still exhibited circulating cancer cells (metastases). After 32-50 weekly injections, ”all colorectal cancer patients exhibited healthy control levels of the serum Nagalase activity, indicating eradication of metastatic tumor cells,”said researchers, an effect that lasted 7 years with no indication of cancer recurrence either by enzyme activity or CT scans, said researchers. [Cancer Immunology, Immunotherapy Volume 57, Number 7 / July 2008] Published in an early online edition of this journal, this confirming report has received no attention by the new media so far, despite its striking importance.

Gc-MAF treatment for cancer has been agonizingly slow to develop. Dr. Yamamoto first described this immuno-therapy in 1993. [The Journal of Immunology, 1993 151 (5); 2794-2802]

In a similar animal experiment published in 2003, researchers in Germany, Japan and the United States collaborated to successfully demonstrate that after they had injected macrophage activating factor (Gc-MAF) into tumor-bearing mice, it totally eradicated tumors. [Neoplasia 2003 January; 5(1): 32–40]

In 1997 Dr. Yamamoto injected GcMAF protein into tumor-bearing mice, with the same startling results. A single enzyme injection doubled the survival of these mice and just four enzyme injections increased survival by 6-fold. [Cancer Research 1997 Jun 1; 57(11):2187-92]

In 1996 Dr. Yamamoto reported that all 52 cancer patients he had studied carried elevated blood plasma levels of the immune inactivating alpha-N-acetylgalactosaminidase enzyme (Nagalase), whereas healthy humans had very low levels of this enzyme. [Cancer Research 1996 Jun 15; 56(12):2827-31]

In the early 1990s, Dr. Yamamoto first described how the human immune system is disengaged by enzymes secreted from cancer cells, even filing a patent on the proposed therapy. [US Patent 5326749, July 1994; Cancer Research 1996 June 15; 56: 2827-31]

Activated Gc protein has been used in humans at much higher doses without side effect. This Gc macrophage activating factor (Gc-MAF) has been shown to be effective against a variety of cancers including breast, prostate, stomach, liver, lung, uterus, ovary, brain, skin, head/neck cancer, and leukemia.

Although GcMAF is also called Vitamin-D binding protein, the activation of macrophages does not require Vitamin D.

It cannot be said the Gc-MAF cancer cure has gone unheralded. Reuters News covered this developing story in January. But the news story still did not receive top billing nor did it fully elucidate the importance of the discovery, actually made years ago, that the human body is capable of abolishing cancer once its immune system is properly activated.

GcMAF is a naturally made molecule and is not patentable, though its manufacturing process is patent protected. There is no evidence of any current effort to commercialize this therapy or put it into practice. Should such an effective treatment for cancer come into common practice, the income stream from health-insurance plans for every oncology office and cancer center in the world Would likely be reduced to the point of financial insolvency and hundreds of thousands of jobs would be eliminated.

The National Cancer Institute estimates cancer care in the U.S. costs ~$72 billion annually (2004). Furthermore, about $55 billion of cancer drugs are used annually, none which have not significantly improved survival rates throughout the history of their use. If a typical cancer patient had to undergo 30 GcMAF injections at a cost of $150 per injection, that would cost ~$4500, not counting doctor’s office visits and follow-up testing. For comparison, gene-targeted cancer drugs range from $13,000 to $100,000 in cost per year and produce only marginal improvements in survival (weeks to months). [Targeted Oncology 2007 April, 2 (2); 113-19]

Up to this point, the National Cancer Institute is totally silent on this discovery and there is no evidence the cancer care industry plans to quickly mobilize to use this otherwise harmless treatment.

Addendum: Sadly, the treatment you have just read about is not available anywhere. Its inventor is attempting to patent a version of it to profiteer off of it even though there is no need to improve upon the GcMAF molecule - - it worked without failure to completely cure four different types of cancer with no long-term remissions and without side effect. While GcMAF is produced by every healthy adult, there are no centers available to extract it from blood samples and inject it into patients with malignancies. Hopefully, someday, doctors will write protocols to do this and submit them to institutional review boards so GcMAF treatment can be performed on an experimental basis. GcMAF is a naturally-made molecule that cannot be patented. This article was written to reveal that there are proven cancer cures that go unused. Of interest, not one oncologist has requested information about GcMAF since this article was written, while I have been barraged with inquires from cancer patients, their families and some interested physicians who are not cancer doctors.
-Bill Sardi

- - -

Based in Southern California, Bill Sardi is a notedand well-known author, lecturer, speaker, and health researcher, with numerous books and articles to his credit. He can be reached at BSardi@aol.com. Timothy Hubbell, a biochemist from Cincinnati, first called attention to this discovery and provided consultation on the biochemistry.

---
http://www.thenhf.com/index.html

Mark said...

Science and Health Series
Is Accumulation of Acid Equal to Aging?

by Sang Whang

Since 1990, I have defined the aging process as the accumulation of non-disposed acidic waste within the body.

Based on this definition, the reduction of accumulated acidic waste is the reverse aging process.

Since then, I introduced a water additive product called AlkaLife®, an alkaline concentrate made of potassium hydroxide and sodium hydroxide in a 3 to 1 ratio respectively.

Lately I came across two academic papers that support my contention and the contents of AlkaLife®.

I can assure you that there have been no collaborations between the authors of these papers and myself.

The first paper is by Drs. Lynda Frassetto and Anthony Sebastian of the University of California, San Francisco, Department of Medicine and General Clinical Research Center. It’s title is Age and Systemic Acid-Base Equilibrium: Analysis of Published Data, published in 19961).

The abstract of the paper is given below.

To investigate whether systemic acid-base equilibrium changes with aging in normal adult humans, we reviewed published articles reporting the acid-base composition of arterial, arterialized venous, or capillary blood in age-identified healthy subjects. We extracted or calculated blood hydrogen ion concentration ([H+]), plasma bicarbonate concentration ([HCO3-]), blood PCO2, and age, and computed a total of 61 age-group means, distributed among eight 10-year intervals from age 20 to 100 years. Using linear regression analysis, we found that with increasing age, there is a significant increase in the steady-state blood [H+] (p<.001), and reduction in steady-state plasma [HCO3-] (p<.001), indicative of a progressively worsening low-level metabolic acidosis.

Blood PCO2 decreased with age (p<.05), in keeping with the expected respiratory adaptation to metabolic acidosis.

Such age-related increasing metabolic acidosis may reflect in part the normal decline of renal function with increasing age.

The role of age-related metabolic acidosis in the pathogenesis of the degenerative diseases of aging warrants consideration.

In layman’s terms, it means that as we get old we have more acid radicals [H+] and less bicarbonate [HCO3-], which brings about age-related metabolic acidosis.

This paper is the recognition and treatment of the symptoms, accepting aging as an inevitable fact of life.

I look at acid accumulation as the cause of physiological aging; therefore, I view the reduction of accumulated acid as the reversal of physiological aging. In addition, acid reduction can prevent all kinds of degenerative aging diseases.

Most everyone else who recognizes acid as the culprit attempts to reduce acid by harder and less effective means, i.e., diet and exercise. I promote the use of potassium and sodium to neutralize acid and bring about acid/alkaline balance. It is well recognized that not only is acid/alkaline balance important, but potassium/sodium balance in the human body is equally, if not more critical.

Another paper that Dr. Frassetto and four other colleagues published supports my contention that our body needs more potassium than sodium. The title of this paper, published in 2001, is Diet, evolution and aging (The pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios in the human diet) 2). Here is the relevant excerpt from the “Summary” of this paper:

Summary Theoretically, we humans should be better adapted physiologically to the diet our ancestors were exposed to during millions of years of hominid evolution than to the diet we have been eating since the agricultural revolution a mere 10,000 years ago, and since industrialization only 200 years ago. Among the many health problems resulting from this mismatch between our genetically determined nutritional requirements and our current diet, some might be a consequence in part of the deficiency of potassium alkali salts (K-base), which are amply present in the plant foods that our ancestors ate in abundance, and the exchange of those salts for sodium chloride (NaCl), which has been incorporated copiously into the contemporary diet, which at the same time is meager in K-base-rich plant foods.

Deficiency of K-base in the diet increases the net systemic acid load imposed by the diet. We know that clinically-recognized chronic metabolic acidosis has deleterious effects on the body, including growth retardation in children, decreased muscle and bone mass in adults, and kidney stone formation, and that correction of acidosis can ameliorate those conditions. Is it possible that lifetime of eating diets that deliver evolutionarily superphysiologic loads of acid to the body contribute to the decrease in bone and muscle mass, and growth hormone secretion, which occur normally with age? That is, are contemporary humans suffering from the consequences of chronic, diet induced low-grade systemic metabolic acidosis?

Our group has shown that contemporary net acid-producing diets do indeed characteristically produce a low-grade systemic metabolic acidosis in otherwise healthy adult subjects, and that the degree of acidosis increases with age, in relation to the normally occurring age-related decline in renal functional capacity. We also found that neutralization of the diet net acid load with dietary supplements of potassium bicarbonate (KHCO3) improved calcium and phosphorus balances, reduced bone resorption rates, improved nitrogen balance, and mitigated the normally occurring age-related decline in growth hormone secretion – all without restricting dietary NaCl. Moreover, we found that co-administration of an alkalinizing salt of potassium (potassium citrate) with NaCl prevented NaCl from increasing urinary calcium excretion and bone resorption, as occurred with NaCl administration alone.

In layman’s terms, potassium deficiency is the cause of many health problems and administering potassium bicarbonate can slow down the normally-occurring age-related low-grade systemic metabolic acidosis and can correct many of the aging symptoms such as calcium and phosphorus imbalances, fast bone resorption rates (slowing down osteoporosis), nitrogen imbalance (reduction of uric acid), etc.

Since Dr. Frassetto’s main interest is to cure patients with these problems, the amount of potassium in AlkaLife® is almost negligible for her. However, AlkaLife® is not designed to cure any diseases, but to prevent the onset of aging symptoms by steady consumption. Consumption of large doses of potassium can cause side effects and must be monitored very carefully by doctors.

I would like to extend my sincere appreciation to the doctors in UCSF for conducting this research and bringing these important facts to the attention of the public.

_____________________________________________________________

1) Journal of Gerontology: BIOLOGICAL SCIENCES, 1996, Vol. 51A. No. 1, B91-B99

2) European Journal of Nutrition, Vol. 40, Number 5 (2001). ©Steinkopff Verlag 2001

© 2004 by Sang Whang Enterprises, Inc.

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http://www.kabencompany.com/article-RII-sang-accumulation-acid-print.html

Mark said...

Green Tea Compound Found to Prevent Type-1 Diabetes

by Mike Adams, the Health Ranger - Key concepts: Green tea, Diabetes and Type-1 diabetes

The miracles of green tea never cease. In this latest research, the green tea compound EGCG has been shown to effectively prevent the onset of type-1 diabetes. This is in addition to green tea's well-documented anti-cancer effects.

What's clear by now is that green tea has amazing healing properties and should be embraced by any society wishing to protect the health of its citizens.

---

Green tea compound may prevent diabetes: study
Thu Nov 6, 2008 2:41pm EST

NEW YORK (Reuters Health) - A compound found in green tea could slow or even prevent the development of type 1 diabetes, new research in mice suggests.

Green tea contains several antioxidants that have been shown to curb inflammation, prevent cell death, and possibly even ward off cancer.

In the current study, Dr. Stephen D. Hsu of the Medical College of Georgia in Augusta and colleagues tested the effects of green tea's predominate antioxidant known as EGCG in laboratory mice with type 1 diabetes and Sjogren's syndrome, which damages moisture-producing glands causing dry mouth and eyes.

They fed the mice plain water or water spiked with 0.2 percent EGCG.

EGCG, the investigators found, reduced the severity and delayed the onset of salivary gland damage associated with Sjogren's syndrome -- a condition with no known cure.

EGCG also dramatically slowed the development of type 1 diabetes in the rodents.

At 16 weeks, they found, 25 percent of the mice given the green tea compound had developed diabetes, compared to 67 percent of the mice given water.

At 22 weeks, 45 percent of the EGCG group had diabetes, while 78 percent of the control group did.

"Our study focused on Sjogren's syndrome, so learning that EGCG also can prevent and delay insulin-dependent type 1 diabetes was a big surprise," Hsu said in a statement.

Both type 1 diabetes and Sjogren's syndrome are autoimmune diseases, which cause the body to attack itself.

Hsu and his team also found that the salivary gland cells that were under autoimmune attack were actually multiplying, but EGCG slowed this proliferation. Such rapid cell division has also been shown to occur in psoriasis.

The current study supports earlier research showing EGCG's impact on helping prevent autoimmune disease, the researchers conclude.

SOURCE: Life Sciences, October 24, 2008.

---
http://www.reuters.com/article/healthNews/idUSTRE4A57ZJ20081106





Related Articles:
• Green Tea Shown to Reduce Risk of Ovarian and Colorectal Cancers

• New herbal supplement product uses green tea and cinnamon for controlling diabetes

• Consumption of green tea associated with reduced mortality in Japanese adults (press release)

• Coca-Cola jumps on green tea bandwagon, launches Enviga beverage with negative calorie claims

• Green tea chemical shows protective effect against Huntington's disease

• Green tea found to significantly reduce risk of death, heart disease

• Interview: Dr. Christine Horner discusses choices women can make to prevent breast cancer

• Green tea found to ease inflammation, arthritis pain

• More Good News on the Benefits of Drinking Green Tea

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http://www.naturalnews.com/News_000450_green_tea_diabetes_type-1_diabetes.html

Mark said...

Winning the War on Cancer

In the book Winning the War on Cancer, author Dr. Mark Sircus discusses sodium bicarbonate, which helps to save countless lives every day.

Sodium bicarbonate is the time-honored method to “speed up” the return of the body’s bicarbonate levels to normal.

It is also the least expensive, safest, and perhaps most effective cancer medicine there is.

Sodium bicarbonate delivers a natural form of [obviously non-radioactive] chemotherapy [since chemotherapy means chemical therapy] in a way that effectively kills cancer cells -- without the side effects and costs of standard [radioactive and self-destructive] chemotherapy treatments.

The only problem with the treatment, according to Sircus, is that it’s too cheap. Since no one is going to make money from it, no one will promote it.


Those that do will be persecuted for it.

The trouble with doing new studies on bicarbonate is that they are expensive and no drug company is going to fund a study when they can't profit from the treatment.

Sources:

* WinningCancer.com

Dr. Mercola's Comments:

In 2008, over 1.4 million new cases of cancer will be diagnosed, and over 1,500 people will die every day from the disease, according to American Cancer Society data.

Despite its prevalence as one of the biggest killers in the modern world, conventional medicine remains completely mystified as to how to address this disease [except to see it as a market to tap and I'm sure they love to see expand.]

Their “solution” to cancer lies with three risky and highly invasive procedures: surgery, chemotherapy and radiation.

The alarming rates of cancer deaths across the world -- cancer has a mortality rate of 90 percent, according to Italian oncologist Dr. Tullio Simoncini -- speak volumes about the effectiveness, or lack thereof, of these treatments, yet they are still regarded as the gold standard of cancer care.

Undoubtedly, many people turn to conventional treatments like chemotherapy because they think they are the ONLY option. But perhaps people would feel differently if they knew that a full 75 percent of doctors say they’d refuse chemotherapy if they were struck with cancer due to its ineffectiveness and its devastating side effects.

“If I were to contract cancer, I would never turn to a certain standard for the therapy of this disease. Cancer patients who stay away from these centers have some chance to make it,” said Professor Gorge Mathe.

You may be surprised to learn that, despite its reputation as the go-to cancer treatment, chemotherapy has an average 5-year survival success rate of just over 2 percent for all cancers, according to a study published in the journal Clinical Oncology in December 2004.

“It is clear that cytotoxic chemotherapy only makes a minor contribution to cancer survival,” the researchers wrote. “To justify the continued funding and availability of drugs used in cytotoxic chemotherapy, a rigorous evaluation of the cost-effectiveness and impact on quality of life is urgently required.”

Chemotherapy is a classic example of a cure that is worse than the disease. In fact, many experts now say that cancer patients are more likely to die from cancer treatments than the cancer itself.

“The majority of the cancer patients in this country die because of chemotherapy, which does not cure breast, colon or lung cancer. This has been documented for over a decade and nevertheless doctors still utilize chemotherapy to fight these tumors,” said Dr. Allen Levin, MD, author of The Healing of Cancer.

There Are Safe, Effective Options Available for Treating Cancer

Yet, you probably haven’t heard of them because they’re simple and inexpensive, and therefore lack the backing to get thoroughly researched and publicized.

Dr. Simoncini explains:

“In the future -- I hope soon -- I am convinced that it will be possible to treat and cure any tumor within 15-30 days with either a pill or an injection in the morning and in the evening when there is targeted pharmacological research. But, again, we now have to work with what we have.”

Is he talking about the latest chemo drug? A radical new surgery? A high-dose radiation treatment? Nope, not even close. Dr. Simoncini is referring to sodium bicarbonate, better known as baking soda.

Dr. Simoncini was ousted from the medical community because as an oncologist -- a cancer specialist -- he refused to use conventional cancer treatment methods, choosing instead to administer sodium bicarbonate..


Dr. Simoncini’s quite amazing experience has shown that 99 percent of breast- and bladder cancer can heal in just six days, entirely without the use of surgery, chemo or radiation, using just a local infiltration device (such as a catheter) to deliver the sodium bicarbonate directly to the infected site in your breast tissue or bladder.

You can watch actual before and after footage of the treatment working in this video.

“Sodium bicarbonate is the time honored method to 'speed up' the return of the body’s bicarbonate levels to normal. Bicarbonate is inorganic, very alkaline and like other mineral type substances supports an extensive list of biological functions. Sodium bicarbonate happens to be one of our most useful medicines because bicarbonate physiology is fundamental to life and health,” Dr. Sircus writes in Winning the War on Cancer.

Many chemotherapy treatments actually include sodium bicarbonate to help protect patients’ kidneys, heart and nervous system. It’s been said that administering chemotherapy without bicarbonate could possibly kill a patient on the spot. Could it be that while mixing chemo poisons with baking soda, any improvements seen are the result of the baking soda, and not the toxic poisons?

Dr. Sircus certainly thinks so.

“There are no studies separating the effects of bicarbonate from the toxic chemotherapy agents nor will there ever be,” he says.

If you keep an open mind, you will quickly learn that there are numerous ways to support your body in healing that have nothing to do with toxic drugs and surgery, even when it comes to a serious condition like cancer.

Another such approach is Dr. Hamer’s German New Medicine (GNM), which operates under the premise that every disease, including cancer, originates from an unexpected shock experience, and that all disease can be cured by resolving these underlying emotional traumas.

Despite a 95 percent success rate, Dr. Hamer has spent time in prison for refusing to disavow his medical findings and stop treating his patients with his unorthodox techniques, and is currently living in exile, seeking asylum from persecution.

What’s Even Better Than a Safe Treatment?

Prevention.

Relatively simple risk reduction strategies can help you to VIRTUALLY ELIMINATE your cancer risk, and radically improve your chances of recovering from cancer if you currently have it.

You won’t read or hear much about these techniques elsewhere either, because they have not been formally "proven" by conservative researchers.

However, were you aware that 85 percent of therapies currently recommended by conventional medicine have never been formally proven either?

That’s something to think about.

Here are the top tips I recommend:

1. Reduce or eliminate your processed food, sugar and grain carbohydrate intake. Yes, this is even true for whole unprocessed organic grains, as they tend to rapidly break down and drive your insulin and leptin levels up, which is the last thing you need to have happening if you are seeking to resolve a cancer.

2. Control your fasting insulin and leptin levels. This is the end result, and can be easily monitored with the use of simple and relatively inexpensive blood tests.

3. Normalize your ratio of omega-3 to omega-6 fats by taking a high-quality krill oil and reducing your intake of most processed vegetable oils.

4. Get regular exercise. One of the primary reasons exercise works is that it drives your insulin levels down. Controlling insulin levels is one of the most powerful ways to reduce your cancer risks.

5. Normalize your vitamin D levels by getting plenty of sunlight exposure and consider careful supplementation when this is not possible. If you take oral vitamin D and have a cancer, it would be very prudent to monitor your vitamin D blood levels regularly.

6. Get regular, good sleep.

7. Eat according to your nutritional type. The potent anti-cancer effects of this principle are very much underappreciated. When we treat cancer patients in our clinic this is one of the most powerful anti-cancer strategies we have.

8. Reduce your exposure to environmental toxins like pesticides, household chemical cleaners, synthetic air fresheners and air pollution.

9. Limit your exposure and provide protection for yourself from radiation produced by cell phones, cell phone towers, base stations and WiFi stations.

10. Avoid frying or charbroiling your food. Boil, poach or steam your foods instead.

11. Have a tool to permanently reprogram the neurological short-circuiting that can activate cancer genes. Even the CDC states that 85 percent of disease is caused by emotions. It is likely that this factor may be more important than all the other physical ones listed here, so make sure this is addressed. One of the best approaches and my particular favorite tool, as you may know, is the Emotional Freedom Technique (EFT).

12. Eat at least one-third of your food raw. Personally my goal is 85% raw and I am usually able to achieve that.

---
http://articles.mercola.com/sites/articles/archive/2008/11/20/winning-the-war-on-cancer.aspx

Mark said...

Nanosilver fad poses 'serious risk to health'

Published Date: 23 November 2008
By Fiona Gray

A NEW internet health craze could be putting thousands of people at risk of developing serious, long-term illnesses, scientists warned last night.

Online retailers are selling drinks and tablets containing silver nanoparticles, claiming the products boost health by killing off harmful bacteria.

The [dangerous] revolutionary particles [that act like asbestos in the body] are being safely and effectively used in bandages and other external treatments, but experts fear internal use could lead to a build-up inside the body, causing brain damage, liver dysfunction and blood diseases.

'Medicines' containing the nanosilver particles – so tiny that 800 would fit side by side on a human hair – are being sold for as little as £4 online as an alternative to antibiotics.

The tablets, drinks and eyedrops are claimed to combat everything from coughs and colds to conjunctivitis.

[However, nanoparticles ARE TOXIC.]


Nanotechnology, the engineering of tiny particles, has boomed in recent years as scientists find uses in a variety of areas, including medicine, electronics and optics.

Nanosilver is the most widely used of the new particles because silver is naturally toxic to most living things, especially bacteria.

Millions of the particles can be created from a gram of the metal – and collectively these have a much greater surface area with which to kill off bugs.

The nano-material's anti-bacterial quality is exploited in a range of products, from medical bandages that prevent wounds from becoming infected to socks that stop feet from smelling and stain-resistant ties.

Online pharmaceutical retailers, both in the UK and United States, have latched on to nanosilver,. . .

But scientists emphasise there is no clinical research into the ingestion of nanosilver, and Scottish nano-technologists were shocked when they found out about the widespread use of such products.

Professor Vicki Stone of Napier University, who was researching the effects of nanoparticles on the body, was recommended nanosilver by her hairdresser.

Her colleague, Professor Ken Donaldson, said: "She was alarmed to hear this woman and her mother were drinking nanosilver almost every day, even though we knew very little about its effect, positive or negative.

"We bought some nanosilver samples from the internet and found that some had very high levels of toxicity. Others were not even silver, and the particles were not nano-sized, but as there is no regulation, people were selling them anyway."

Donaldson, chairman of respiratory toxicology at the University of Edinburgh, said: "There are entire textbooks written on the toxicity of metals and you don't want to disturb the balance in your body. There are studies where animals have been fed nanosilver and you can detect the harmful effects on their weight and general health.

"I would like to see how these products are testing themselves and claiming to be safe for children. The same dose of silver would be diluted less in a child because they have less body water."

A 2005 study by Dr Max Fung of the University of California suggested that taking nanosilver could cause argyria, a condition that turns the skin bluish-grey, and high doses could lead to comas and anaemia.

Dr Ken Lawton, of the Royal College of General Practitioners, said: "I am very concerned that patients are taking an untried and untested product, particularly a metal, because there is evidence they accumulate and will target organs like the liver, the brain and bone marrow."
...

'Magic spray'

Alexa Bentley, 59, a semi-retired property consultant from north London, has used colloidal silver for 13 years.

She drinks it, gives it to her daughter, feeds it to her eight pet dogs and sprays her whole house with it. "It's magic spray," she said. "I take it whenever I'm starting to feel ill, and now I hardly ever get a cold."

Bentley heard about colloidal silver through a friend who had used it on her dog. She said: "The vet was about to operate on the dog because antibiotics had failed to clear up an infection, but they put colloidal silver on and it cleared up literally overnight.

"I got really interested when I had an ulcer in my mouth. I sprayed the stuff in my mouth and the next morning it was gone. It's comforting at first, and then it repairs. It's completely natural.

[Temporary things I can see it perhaps being justified, particularly if nothing else worked to remove bacterial infections, though when there are options surely the best thing to do is avoid heavy metal toxicity as an 'option'. The nanoparticle toxicity is another issue.]

...

* Last Updated: 22 November 2008 7:30 PM
* Source: Scotland On Sunday
* Location: Scotland

---
http://scotlandonsunday.scotsman.com/latestnews/Nanosilver-fad-poses-39serious-.4722412.jp

Mark said...

Resveratrol Longevity Secret Unlocked by Scientists: It's the Chromosomes!

by Mike Adams, the Health Ranger, November 27, 2008

Key concepts: Resveratrol, Longevity and Chromosomes

What is it, exactly, about resveratrol that makes it one of the most miraculous nutrients that's ever been discovered by modern science? We already know resveratrol helps reverse heart disease, stops cancer and has a powerful anti-aging effect, but how exactly does it work?

Scientists from Harvard Medical School think they've found some clues. In research published in the journal Cell, they've documented how resveratrol activates a protein called sirtuin that performs an almost miraculous gene repair resulting in extended lifespan.

Their research concludes that sirtuin repairs breaks in human chromosomes, and resveratrol seems to activate sirtuin in just the right way to prevent the accumulation of chromosomal damage that leads directly to aging.

Of course, these scientists aren't really studying nature for the benefit of humankind: They're looking for the next miracle pharmaceutical, and they're ripping off molecules from Mother Nature in order to find it (and patent it).

Just watch: In five years when this drug is approved by the FDA, they'll claim the drug is a miracle but resveratrol is useless.

It's the same scam they played with red yeast rice, from which the molecules used to synthesize statin drugs were stolen.

The truth is that resveratrol is a miracle nutrient all by itself, and we don't need to have it patented in order to benefit from it. Just buy resveratrol supplements right now and you can experience the anti-aging benefits (and heart protection benefits) for yourself!

A resveratrol supplement company I recommend is Byron Richards' Wellness Resources (www.WellnessResources.com), which sells a variety of anti-aging supplements, including resveratrol.

The specific product I recommend there is called Cardio Helper: http://www.wellnessresources.com/produc...

(I have no financial ties to Wellness Resources.)

In fact, Byron Richards recently wrote a feature article on resveratrol that we published on NaturalNews. Check it out here:

http://www.naturalnews.com/024930.html, located below as well:

Is Resveratrol the Fountain of Youth?

Thursday, November 27, 2008 by: Byron Richards, Health Freedom Editor

Key concepts: Resveratrol, Leptin and Food

Breaking News for Thursday, November 27, 2008

Articles Related to This Article:

• Resveratrol Has Anti-aging and Anti-Cancer Properties, Linked to Cardiovascular Health

• Resveratrol Found to Halt Growth of Pancreatic Cancer Cells

• Red Wine’s Resveratrol May Help Battle Obesity

There are a lot of great anti-aging and metabolism boosting nutrients: DHA, pantethine, acetyl-l-carnitine, carnosine, R-alpha lipoic acid, grape seed extracts – the list goes on and on.

In fact, most nutrients help cells function better and thus live longer.

So, why is resveratrol vying for the position as King of the anti-aging nutrients – with a potent fat-burning twist thrown in for good measure?

Maybe we should ask Big Pharma, who is spending a pile of cash on metabolites of resveratrol that they hope to patent as weight loss drugs, diabetes drugs, and a new generation of anti-aging medicines.

Part of the way resveratrol works is by activating a powerful metabolic fat-burning and anti-aging gene called SIRT1.

In newly published Big Pharma animal research, their resveratrol drug activated SIRT1, prevented weight gain on a high fat diet, improved blood sugar and insulin function, and doubled the exercise endurance of the mice.

Interestingly, resveratrol dietary supplements have been shown to do essentially the same thing. The resveratrol drug (SRT1720) is apparently six times more potent at activating SIRT1 than plain resveratrol.

However, plain resveratrol operates in a number of different ways besides activating SIRT1, providing a broader base of potential health benefits including comprehensive cardiovascular support.

What is Resveratrol?

Interest in resveratrol research took off when it was identified as a component in red wine that may be partly responsible for the "French Paradox," the ability to eat a higher fat diet with less heart disease than Americans. Research shows that resveratrol helps your liver metabolize fat and helps break down stored fat contained in your white adipose tissue.

Resveratrol is a type of polyphenol known as a stilbenoid, which is produced in grapes and blueberries to protect themselves from bacterial and fungal infection, and to a lesser extent from UV radiation.

It was discovered that grapes growing in damp and moldy areas had the highest content of resveratrol of any known commonly consumed food/beverage.

Resveratrol is obviously a potent anti-fungal compound and antioxidant.

Resveratrol is a different compound than the flavonoid proanthocyanidins of grape seed extracts, which also contribute to the notion of the French Paradox.

Blueberries, by comparison, also contain flavonoids and a different stilbenoid called pterostilbene (pronounced "tero-STILL-bean").

Significant research at the USDA has shown that pterostilbene has a powerful ability to influence the metabolism of cholesterol and the synthesis of triglycerides by improving metabolism within cells, as well as providing brain-protecting anti-aging properties.

The amount of resveratrol in a bottle of red wine varies from 2 mg to 14 mg, mostly on the lower side.

Dietary supplements of resveratrol are typically derived from the roots of Japanese knotweed (Polygonum cuspidatum), a far more economical source than grapes.

Doses will range from a basic protective dose of a few milligrams (like a bottle of red wine), up to 100 mg per serving or more (a therapeutic dose).

Resveratrol is readily absorbed, reaching peak blood levels in 30 minutes, and then rather rapidly cleared by your liver.

Thus, it is better to spread out intake during the day than to take a large amount all at once.

At this point, other than the colorful history and longevity benefits associated with red wine consumption, the majority of the extensive resveratrol research has been carried out with cell studies and small animals. The implications of this research are mind-boggling, clearly showing significant extension of life span.

The Fat-Burning and Anti-Aging Properties of Resveratrol

SIRT1 first drew attention as the primary gene signal involved with the longevity benefits of calorie restriction. A very simple explanation is that when you are in a food scarcity situation, SIRT1 is activated so as to help break down your stored fat to use as fuel as well as to boost up your energy so that you have enough energy to hunt for new food. SIRT1 is part of a famine-related survival system.

Many experiments with animals show that by restricting calorie intake, SIRT1 is naturally activated, a finding that goes along with a noticeably extended lifespan, better fat and cholesterol metabolism, more efficient immune function, and better cardiovascular health.

A number of humans have taken up calorie restriction experiments on themselves, and pictures of them do not portray the portrait of health.

In fact, you would be hard pressed to pick out of a line-up someone on a self-induced calorie restriction diet and someone coming in for anorexia treatment. Which gets to my point, what is the difference between a calorie restriction diet and anorexia?

I have studied the calorie restriction science for 20 years and I am also the leading diet expert on the fat-derived hormone leptin, which is the overall boss hormone that controls your metabolic rate and your ability to survive a period of famine. Thus, I will give you answers in this area that you won't find elsewhere. There is a very fine line between prolonged calorie restriction and anorexia.

In the case of someone consuming too much food, their extra pounds of fat crank out inflammatory messengers (TNFa and IL6), in turn stimulating the liver to make the inflammatory CRP. This combination of inflammation induces significant free radical damage in the circulatory system and all around the body. As the waistline expands the volume knob on inflammation and free radical production is turned up. At the same time the liver becomes clogged with fat, which in turn is "cooked" by free radicals from the inflammation, eventually sending the liver on the path to looking like a fried piece of bacon.

Arteries are also getting fat around the outside of the arterial wall structure [when they are damaged by radicals and the fat is the 'cheap fix' of the body attempting to heal it, instead of it related to "too much cholesterol"--cells are made of cholesterol, if you body is damaged by free radicals, only then is there cholesterol buildup], in turn generating more inflammation to the inside of arteries and deactivating friendly nitric oxide production.

This makes blood pressure go up and blood not flow well and further induces free radical production in arteries that damages LDL cholesterol, promoting the formation of plaque.

In this scenario leptin levels are also high (leptin resistance), which lowers another fat-derived hormone called adiponectin, in turn causing a bad mood and insulin resistance that leads to type II diabetes. Leptin problems cripple thyroid function as well as promoting never-ending cravings to eat more food. This is the precise metabolic profile of millions of Americans on the fast track to diabetes, heart disease, and poor health.

Ironically, they are being poisoned to death by too much food with no easy way out of the misguided subconscious drive to continue excess eating.

It is important to understand that just about everyone who is overweight and having trouble with their cravings has high leptin in their blood (leptin resistance), and that leptin is not getting into their brains correctly (a false state of misperceived starvation).

Leptin resistance is caused by consistently eating meals that are too large, by eating after dinner at night, and by snacking.

Human beings do not have the genes to deal with the abuse of eating too much food, as during evolution this was never the problem.

Rather, a scarcity of food was the primary issue that constantly threatened the survival of the human race – and so it is that we have a lot of mechanisms built in to help deal with starvation.

The ability to survive famine is controlled by leptin.

During famine leptin levels have gone low as your fat mass that secretes leptin in the first place has been reduced in size to use the stored fat for energy, which is how your subconscious brain knows a famine is occurring.

In response to this low-leptin famine issue, your liver turns on the production of SIRT1.

This helps your liver know to break down fat to use as fuel, not store calories as fat, as well as to boost physical energy to be able to hunt or gather new food.

Considering all the interest in both SIRT1 and leptin, the number of studies linking the function of the two is remarkably absent from the literature.

New research shows that SIRT1 is active in key regions of your brain that relate to appetite and energy, which are governed by leptin.

Leptin deficient mice do not activate SIRT1 properly, and are always obese. The details of this relationship are far from clear. It is easy to predict that low levels of leptin from true starvation are able to trigger SIRT1 activation in your liver based on messages received from SIRT1 signaling systems in your brain.

It is also easy to predict that high levels of leptin in your blood (obesity-related leptin resistance) turn SIRT1 off as they would be signaling your liver that famine is over or not happening.

As you begin to diet (especially if you follow the Leptin Diet) and drop your first 10-15 pounds you will clear high leptin from your blood, which is always reflected by your cravings going away.

For a while your body is set to burn more calories based on your pre-dieting metabolic set point.

The problem for many people is that you hit a plateau after a month or so of dieting that is too far from your goal weight.

If you eat less you can't function. Your head is heavy, you are irritable, your sleep gets disturbed, your immune system goes on the blink, and you are much more likely to get sick. If you exercise more you must eat more or you will be completely exhausted and feel even worse. If you get stressed, unlike the stress-free monkeys practicing calorie restriction, you are in real trouble and likely to eat the house down. Yes, you are practicing calorie restriction – how on earth is this state of feeling going to help you live longer? Answer – its not. You start generating inflammation the longer you are in this condition.

The inflammation is no longer coming from your extra pounds of fat. It is coming from the trauma of the diet combined with stressors in your life.

Under these circumstances you are much more likely to break down muscle, a key sign of inappropriate weight loss. If you keep trying to lose weight while you feel this way you may be able to do so, but you will progressively lose more muscle, increase inflammation, generate a lot of free radical damage, disturb digestion, get sick really easily, and presto – you are anorexic. Funny thing is, you may still be an overweight anorexic. Wow – is that any way to diet?

Eating in harmony with leptin
If you start eating more food you will feel much better. Unfortunately, you messed with leptin in the wrong way. Leptin now turns off SIRT1 and goes into a famine-recovery mode. It commands that a large portion of the calories you are now eating go back to fat storage. Most people find themselves rapidly gaining weight on formerly normal amounts of food.

Once the yo-yo routine comes to a halt you are likely to find yourself 5-10 pounds heavier than when you first started, as an insurance policy in case you attempt another dieting stunt in the future.

Solving this dilemma requires that you eat in harmony with leptin, which means following the five simple rules of the Leptin Diet.

In many cases you will never hit this problematic plateau. However, many people will, especially if they have a history of yo-yo dieting. Enter resveratrol. Resveratrol is an ideal nutrient to enhance weight loss and maintain energy ONCE YOU HAVE GOTTEN PAST THE INITIAL PHASE OF 10-15 POUNDS OF WEIGHT LOSS, especially if you are getting stuck at a plateau.

Resveratrol will help turn on the SIRT1 gene, which will promote fat-burning in the presence of lower calorie intake. This is a terrific use of this nutrient.

How do you know it's working? You have energy to exercise, you feel good, and your weight is trending downward while you are happy eating less food. This either is or isn't happening, thus it isn't very hard to figure out if resveratrol helps you.

How resveratrol enhances your weight loss efforts
One of the real values of this nutrient in the weight management context is helping you to not slide into an inflammatory anorexic-like metabolic problem as you try to lose weight. It is also a tool to help you break through weight loss plateaus should they occur.

Resveratrol will work best when you are eating less food and have already cleared surplus leptin out of your blood through initial dieting efforts. However, you don't need to eat so little that you are on the scarecrow diet.

Research indicates that resveratrol will still help you out even if you aren't dieting or you don't need to lose weight. After all, the French had resveratrol in their diet when they were mostly thin. I might point out, however, that while the French were eating a higher saturated fat diet they were not overeating, their food was fresh and mostly organic, and they did not snack. The effects of resveratrol will be easily overloaded by overeating. Even the French Paradox has been doomed by an epidemic of leptin-disrupting snacking and junk food consumption.

Having a large waistline is clearly linked to premature death, a risk that goes up in direct proportion to your waistline's rate of expansion. Anything safe and natural that can help you get it back to optimal and keep it that way qualifies as life extending.

Cardiovascular and Other Benefits of Resveratrol

Simply losing weight healthfully will improve your cardiovascular health. If resveratrol is able to help you in this endeavor, regardless of any other cardiovascular help it provides, then it is a success as a cardio-friendly nutrient.

There is plenty of animal and cell science to predict that resveratrol assists the healthy structure and function of your cardiovascular system in multiple ways. It has been found to reduce the stickiness or adherence of immune cells to the walls of arteries, prevent adverse changes in the smooth muscle cells of arteries that lead to plaque accumulation, boost friendly nitric oxide levels (eNOS) that relax arteries and improve blood flow, help keep platelets from sticking together, reduce irregular heart beats, and reduce circulatory inflammation. It even helps protect against circulatory damage from high blood sugar.

Keep in mind that in "modern" medicine, each one of these points requires a different drug that has other adverse side effects.

One of the first human resveratrol studies shows that resveratrol improved heart function in type II diabetic patients following a heart attack.

Resveratrol, like grape seed extract, operates in part as a protector of human body structure.

This is clearly related to its anti-oxidant and anti-inflammatory properties, which include regulation of the primary inflammatory gene switch NF-kappaB.

New animal and cell studies shows it helps bone health, reduces cataracts, helps coordination, reduces disk deterioration and protects joints, guards against Parkinson's, improves erectile performance, protects the liver, protects the pancreas, and helps regulate cell health while protecting against adverse cell changes.

This is a rather impressive array of science-backed support for any one nutrient. Maybe the anti-aging promise is real. The explosion of scientific interest in the compound ensures that you will be hearing a lot more about it in the very near future.

Common doses of resveratrol that show benefit and safety in animal studies range from 2.5 mg – to 10 mg per kilogram. This translates to an approximate dose range of 150 mg – 700 mg per day for a 150 pound adult, a sensible and safe dose range until more data is in.

For a fully referenced version of this article:

http://www.wellnessresources.com/tips/articles/is_resveratrol_the_fountain_of_youth/

For more health articles by this author:

http://www.wellnessresources.com/health_news.php

About the author: Byron J. Richards, Board-Certified Clinical Nutritionist, nationally-renowned nutrition expert, and founder of Wellness Resources is a leader in advocating the value of dietary supplements as a vital tool to maintain health. He is an outspoken critic of government and Big Pharma efforts to deny access to natural health products and has written extensively on the life-shortening and health-damaging failures of the sickness industry. www.wellnessresources.com askbyron@wellnessresources.com

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http://www.naturalnews.com/024930.html

Mark said...

Scientists Find Clues to Aging in a Red Wine Ingredient’s Role in Activating a Protein

By NICHOLAS WADE
Published: November 26, 2008

A new insight into the reason for aging has been gained by scientists trying to understand how resveratrol, a minor ingredient of red wine, improves the health and lifespan of laboratory mice. They believe that the integrity of chromosomes is compromised as people age, and that resveratrol works by activating a protein known as sirtuin that restores the chromosomes to health.

The finding, published online Wednesday in the journal Cell, is from a group led by David Sinclair of the Harvard Medical School. It is part of a growing effort by biologists to understand the sirtuins and other powerful agents that control the settings on the living cell’s metabolism, like its handling of fats and response to insulin.

Researchers are just beginning to figure out how these agents work and how to manipulate them, hoping that they can develop drugs to enhance resistance to disease and to retard aging.

Sirtris, a company Dr. Sinclair helped found, has developed a number of chemicals that mimic resveratrol and are potentially more suitable as drugs since they activate sirtuin at much lower doses than resveratrol. This month, one of these chemicals was reported in the journal Cell Metabolism to protect mice on fatty diets from getting obese and to enhance their endurance in treadmills, just as resveratrol does.

Though the sirtuin field holds considerable promise, the dust has far from settled. Resveratrol is a powerful agent with many different effects, only some of which are exerted through sirtuin. So drugs that activate sirtuin may not be as splendid a tonic for people as resveratrol certainly seems to be for mice.

The new finding concerns maintenance of the chromosomes, the giant molecules of DNA that make up the genome.

Each cell has six feet of DNA packed into its nucleus, carrying the 20,000 or so genetic instructions needed to operate the human body. Each cell must provide instant access to the handful of these genes needed by its cell type, but also keep the rest firmly switched off to avoid chaos.

Sirtuin’s normal role is to help gag all the genes that a cell needs to keep suppressed. It does so by keeping the chromatin, the stuff that wraps around the DNA, packed so tightly that the cell cannot get access to the underlying genes.

But sirtuin has another critical role, one that is triggered by emergencies like a break in both DNA strands of a chromosome. After a double strand break, sirtuin rushes to the site to help knit the two parts of the chromosome back together. But in this salvage operation, it leaves its post, and the genes it was repressing are liable to come back into action, causing mayhem.

This, Dr. Sinclair and his colleagues suggest, may be a fundamental cause of aging in mice and probably people, too.

The gene-gagging role of sirtuin was discovered in the 1980s by biologists studying yeast, a standard laboratory organism. Dr. Sinclair and Leonard Guarente of the Massachusetts Institute of Technology found in 1997 that sirtuin could also repair a certain kind of genomic damage in yeast, and in doing so extended the yeast cell’s lifespan. But this particular kind of damage does not occur in mammalian cells, raising the puzzle of why extra sirtuin should be good for them.

Dr. Sinclair’s new report, if verified, resolves this problem by showing that sirtuin has retained its genomic repair role in higher organisms but that the repair is focused on a different kind of genomic damage — that of breaks in a chromosome.

These experiments “elegantly demonstrate” that sirtuin works in much the same way in mammals as in yeast, Dr. Jan Vijg of the Albert Einstein College of Medicine wrote in a commentary in Cell. The question now is whether sirtuin is a pro-longevity factor in mammals, he said in an e-mail message.

Ronald Evans, a biologist at the Salk Institute, said the new report was provocative but did not prove the case that the relocation of sirtuin was a cause of aging. Tests with mice genetically engineered to lack the sirtuin gene could show if the mice suffered from premature aging, as Dr. Sinclair’s idea would predict.

Dr. Sinclair said he agreed that the case for sirtuin’s role in aging had not been proved. “We are careful not to say this is the cause of aging, but based on everything we know it’s not a bad hypothesis,” he said.

It would be nice to test aging in mice that lack the sirtuin gene, as Dr. Evans proposed, but they die too young, Dr. Sinclair said.

Dr. Sinclair has been taking large daily doses of resveratrol since he and others discovered five years ago that it activated sirtuin. “I’m still taking it, and I feel great,” he said, “but it’s too early to say if I’m young for my age.”

---
http://www.nytimes.com/2008/11/27/health/27aging.html?_r=1&ref=us

Mark said...

Gut/Brain Chemical Serotonin, Tied to Bone Formation/Loss

Bone Finding May Point to Hope for Osteoporosis

By GINA KOLATA
Published: November 26, 2008

Bone formation appears to be controlled by serotonin, a chemical previously known mainly for its entirely separate role in the brain, researchers are reporting.

The discovery could have enormous implications, osteoporosis experts say, because there is an urgent need for osteoporosis treatments that actually build bone.

Osteoporosis affects 10 million Americans over age 50. It results in bone loss, and its hallmark is fragile bones that break easily.

[Additionally, a dietary balance between calcium and phosphorous matters. Drinking drinking milk (high in calcium without phosphorous) messes up this balance and leaches phosphorus from the bone, ergo, osteoporosis. See notmilk.com for more]

With one exception, current treatments only slow further bone loss rather than increase bone formation. And the exception, parathyroid hormone, given by injection, is recommended only for short-term use and costs about $6,700 a year.

But in a paper published online Wednesday in the journal Cell, a team led by Dr. Gerard Karsenty, chairman of the department of genetics and development at the Columbia University College of Physicians and Surgeons, reports the discovery of an unexpected system that appears to control bone formation.

At its heart is serotonin made by the gut rather than the brain, whose role outside the brain had been a mystery. Ninety-five percent of the body’s serotonin is made by the gut, but gut serotonin cannot enter the brain because it is barred by a membrane, the so-called blood-brain barrier.

Dr. Karsenty reports, though, that gut serotonin can directly control bone formation. It is released into the blood, and the more serotonin that reaches bone, the more bone is lost. Conversely, the less serotonin, the denser and stronger bones become.

[i.e., frail, intelligent people, bony stupid people ;-)]

Dr. Karsenty was even able to prevent menopause-induced osteoporosis in mice by slowing serotonin production. [Though you are making people stupider?]

Osteoporosis researchers were dumbfounded by the report.

“I am very excited by this paper,” said Dr. J. Christopher Gallagher, an osteoporosis specialist and professor of medicine at Creighton University. “It is a groundbreaking paper. One is completely surprised.”

Dr. Ronald N. Margolis, senior adviser for molecular endocrinology at the National Institute of Diabetes and Digestive and Kidney Diseases, said: “I was astonished. My jaw was dropping.”

Dr. Clifford J. Rosen, a senior scientist at the Maine Medical Center Research Institute, was no less impressed. “This is amazing science,” Dr. Rosen said. “Amazing. The science is spectacular.”

Dr. Ethel S. Siris, who directs the Toni Stabile Osteoporosis Center at Columbia, cautioned that the work was not with humans but instead involved mice that were engineered to have human genes. “This stuff is really exciting basic — underscore basic — research,” Dr. Siris said.

The story of the serotonin-bone connection began with reports of a rare inherited condition causing fragile bones and blindness. Children with the condition had bones so weak that they needed wheelchairs or devices to assist them in walking.

The problem turned out to be a mutation that inactivated a gene called LRP5.

A few years later, another mutation was found in LRP5 that produced the opposite effect: extremely dense bones and resistance to osteoporosis. In this case, LRP5 was overactive. People with this gene mutation, Dr. Karsenty said, had jawbones so dense that it was difficult to extract their teeth.

Osteoporosis researchers jumped on those findings, realizing that LRP5 could hold clues to the disease. But most assumed that LRP5’s role was in bone itself.

With Dr. Karsenty’s work, said Dr. Bjorn R. Olsen, a bone growth researcher at Harvard Medical School, “that has now been proven completely wrong.”

Instead, Dr. Karsenty discovered that LRP5 acts on serotonin-producing cells in the gut. It blocks an enzyme that converts the amino acid tryptophan to serotonin. The more LRP5, the more the enzyme is blocked, and the less serotonin is made. The gene has no effect, apparently, on brain cells that make serotonin.

After the gut releases serotonin into blood, serotonin travels to bone-forming cells and inhibits their growth.

“We made mice with the inactivated gene,” Dr. Karsenty said, in which “the bone-forming cells are on strike.” The cells simply would not grow, and the mice developed severe osteoporosis.

But the bone cells themselves were fine. When Dr. Karsenty grew them in the lab, where they were not exposed to serotonin, they developed normally.

That told him that the problem was not in the bone cells but in some molecule in the mice’s circulation. And that, Dr. Karsenty says, led him to serotonin. The mice had four to five times more serotonin in their blood than mice without the mutation.

He tested the idea by adding serotonin to normal mouse bone cells in the laboratory. The cells stopped growing.

He could even control bone formation in the mice with the mutated gene by giving them a diet deficient in tryptophan, the precursor of serotonin. Without much tryptophan, the mice could not make much serotonin. And their bones grew denser. (But animals with a normal version of the gene did not grow denser bones when they ate a tryptophan-deficient diet.)

Dr. Karsenty and his colleagues also did the reverse experiment, making mice with the mutation that causes superdense bones in humans. Those animals, he said, had “amazing bones” that were hard to break, and they did not develop osteoporosis.

When Dr. Karsenty looked at patients with the dense-bones mutation, they had low levels of serotonin in their blood.

Osteoporosis patients, though, tend to have normal serotonin levels, Dr. Karsenty said. Their disease involves not impaired bone formation but accelerated bone loss.

Bone is constantly being formed and absorbed, but when the balance shifts toward loss more than formation, the result can be osteoporosis. Dr. Karsenty’s hope is to find a drug that depresses the gut’s serotonin synthesis and stimulates bone growth in these patients.

Dr. T. John Martin, an emeritus professor of medicine at the University of Melbourne in Australia, cautions that all this will take years. He is enthusiastic, though.

“This will really change thinking in the field,” Dr. Martin said. “It will have a big impact. I’m certain of that.”

---
http://www.nytimes.com/2008/11/27/health/research/27bone.html?em

Mark said...

Meditation 'beats [chemical] antidepressants'

Published Date: 01 December 2008


GROUP psychology involving Buddhist meditation can be as effective at combating depression as medication, a study published today in the Journal of Consulting and Clinical Psychology has found.

Fifteen months after an eight-week trial, [only] 47 per cent of people with depression who under-went therapy suffered a relapse, compared with [more people suffering a relapse if they were on chemical medicine, i.e., ] 60 per cent of those taking antidepressants.


The full article contains 61 words and appears in The Scotsman newspaper.

1
!Ya basta!,
01/12/2008 01:15:37
Glad somebody has done some research to support what many already believe. Now lets hope that the medical profession/administration can start referring more folk to healthier treatment such as meditation, where it is available

4
Vincent-W,
01/12/2008 12:41:43

There was another study with Catholic nuns, which found the frequency of dementia was much lower in convent populations compared to the population at large. The difference they found was also put down to the beneficial effects of meditation and prayer.

5
TimW1234,
Ottawa, Canada 01/12/2008 18:49:32
I know this is personal and anecdotal and hope I don't get pilloried by Vincent, but I have a very close friend who is an insulin-dependent diabetic and meditates daily.

He says it lowers or levels his blood-sugar levels and has been approved by his endocrinologist.

The two or three glasses of RED wine per evening may also help. These are also encouraged and condoned by our endocrinologist. She is also an epidemiologist at two of the universities here.

But he meditates in the morning and doesn't imbibe until after 5:30 p.m. He has more self-control than do I.

Also, Vincent, did that study of nuns also include the lack of stress in their lives and the almost reverential and hushed environs of nunneries (convents) - and monasteries?

---
http://news.scotsman.com/uk/Meditation-39beats---.4746662.jp

Mark said...

[more on stem cells and 'correcting' the brain with them after a stroke]


Miracle 'teabag' [temporary patch of stem cells in the brain] helps stroke victim to speak again

A stroke victim has regained the power of speech after doctors placed a device resembling a teabag filled with stem cells in his brain.


By Murray Wardrop
Last Updated: 7:35AM GMT 03 Dec 2008
Miracle 'teabag' helps stroke victim to speak again

Genetically modified stem cells fitted into a kind of 'tea bag' are implanted to the patient's brain where they are supposed to have an anti-inflammatory effect Photo: EPA

Walter Bast, 49, also regained the use of his right arm after the revolutionary treatment, which prevents brain cells from dying.

If further trials of the treatment are successful, it could be on the market in as little as five years, providing fresh hope for the 45,000 Britons each year who suffer a haemorrhagic stroke, where a blood vessel in the brain bursts.

Currently, the only option is surgery, which has a variable success rate. Half of surgery patients will die within a month and just one in 20 patients will recover to the extent of Mr Bast.

The pioneering treatment, called CellBeads, involves cutting away part of the skull to tie off leaking blood vessels and remove blood from the brain.

Surgeons then insert the 2cm by 2cm 'teabag' filled with capsules stuffed with around a million stem cells.

The stem cells, taken from bone marrow, have been genetically engineered to make a drug known as CM1 that protects brain cells from dying. This lets the cells rejuvenate and repair the damage done by the stroke.

After around two weeks, doctors at the International Neuroscience-Institute in Hanover, Germany, removed the 'teabag', resulting in Mr Bast regaining his speech and the use of his right arm.

Speaking a week after the operation, the first of its kind in the world, Mr Bast, a mechanic, said: "I feel a lucky guy."

The so-called CellBeads treatment is the brainchild of scientists at the British medical technology firm Biocompatibles International, based in Farnham, Surrey.

The stem cells are encapsulated in beads to hide them from the immune system and ensure they are not rejected by the body.

Enclosing everything in the 2cm square 'teabag' ensures the surgeon can easily remove it at the end of the treatment period.

Mr Bast, who lives near Bremen in Germany, agreed to be the first to test the operation after suffering two strokes in quick succession.

His surgeon, Professor Thomas Brinker, said: "We see a recovery as good as this in only the minority of patients, so it is an encouraging start. It is important that we found no side-effects."

Dr Peter Stratford, of Biocompatibles, said a one-size-fits-all treatment could be stored in hospital freezers ready for use when required.

If effective, it could have a huge impact on patients' quality of life and save the NHS billions.

But stem cell scientists warned that many safety and ethical hurdles would have to be crossed before the treatment was accepted for widespread use.

Haemorrhagic strokes account for around 30 per cent of the 150,000 strokes in the UK each year.

Stroke is Britain's third biggest killer, after heart disease and cancer, and causes more disability than any other disease. It costs the economy about £7 billion a year, including NHS bills and lost productivity.

---
http://www.telegraph.co.uk/health/healthnews/3543937/Miracle-teabag-helps-stroke-victim-to-speak-again.html

Mark said...

Folic Acid: What it is; Health Conditions Related to Deficiency

Folic acid deficiencies are widespread; here's why nearly everyone needs more folate

Thursday, December 29, 2005 by: Alexis Black, citizen journalist
Key concepts: Folic acid, Folate and Vitamin B


Articles Related to This Article:
• Folic Acid May Prevent Cancer of Larynx (press release)

• Folic Acid Fortification: One Size May Not Fit All

• Prenatal vitamins shown to reduce children's risk of cancer



Pregnant women plagued by cravings for pickles and ice cream must remember to include plenty of folic acid in their diets. Shown to reduce the risk of miscarriage and birth defects, folic acid – found primarily in leafy green vegetables – is an absolute necessity for any woman who is pregnant or is considering becoming pregnant.

In fact, "health officials at the U.S. Centers for Disease Control and Prevention (CDC) now recommend that all women of childbearing age take folic acid (0.4 mg daily) to protect their future newborns from developing a neural tube defect, an anomaly of the spinal cord," writes Burton Goldberg in Alternative Medicine.

However, it's not just expectant moms who could stand to add more leafy greens to their plates. Because it is useful in combating everything from acne and canker sores to osteoporosis and cancer, we could all benefit from adding more folic acid to our diets. Along with pregnant women, elderly individuals and people suffering from depression or nervous system disorders especially stand to gain from the addition of this B vitamin.

Folic acid, the synthetic form of the B vitamin folate, works primarily in the brain and nervous system and is necessary for the synthesis of DNA, the production of red and white blood cells and of norepinephrine and serotonin in the nervous system. Folic acid also aids in the elimination of the amino acid homocysteine from the blood, a breakdown product of animal protein (methionine, actually) that contributes to heart attacks. A lack of folic acid can lead to anemia, insomnia, irritability and far more serious health problems.

Despite its range of health benefits, many Americans are deficient in the vitamin, coming nowhere near the government's recommended daily allowance of 200 micrograms daily. "The average American gets only 61 percent of the old Recommended Dietary Allowance, which is too low anyway," says James Duke, PhD in Anti-Aging Prescriptions. Part of the reason for the shortfall is that more Americans are choosing to eat more animal foods – which are a poor source of folic acid – rather than folic-acid rich plant foods, like dark green vegetables, legumes, root vegetables and whole grains.

Dr. Andrew Weil, in Ask Dr. Weil, recommends the use of supplements to make up for the deficiency. "As many as 90 percent of Americans don't get that protective 400 micrograms in their diet – for example, you'd have to eat two cups of steamed spinach, a cup of boiled lentils, or eight oranges every day. So it's important to take a supplement, especially if you're a woman and considering having children someday." As Dr. Weil suggests, for women who are deficient in this essential vitamin, the health costs can be especially high.

Folic acid is essential for pregnant women. Not only does it protect against cervical cancer, it also aids in healthy prenatal development and can significantly reduce the risk of serious neural tube birth defects and abnormalities that occur in very early fetal development, such as spina bifida. However, experts say most women aren't getting adequate levels of folic acid early enough to offer the best protection against birth defects.

"Very few women of child bearing years are taking folic acid… If a person waits until pregnant, the fetal abnormality is already established. All women of child-bearing age who might become pregnant should be taking 400 mg of folic acid," advises Dr. James Howenstine in A Physicians Guide To Natural Health Products That Work. To make matters even more difficult, women who take birth control pills are especially prone to deficiency in the B vitamin since birth control pills actually produce folic acid deficiency.

Men planning to become fathers need to monitor their folic acid intake as well, as low folic acid levels in males has been linked to low sperm count, and some studies suggest deficiency can also damage DNA carried by the sperm. Such damaged DNA could lead to chromosomal damage in a fetus, according to Bottom Line Yearbook 2004. In other words, both men and women who plan to have children should increase their folic acid intake for the sake of their baby-to-be.

Folic acid promotes good health for the mind and body, from the earliest stages of life to the latest. Men and women over 60 who feel fatigued and depressed may simply be suffering from a folic acid deficiency. In fact, folic acid deficiency has been linked to depression in patients of all ages, and according to Gary Null'sComplete Guide of Natural Healing, "the lower the level of folic acid in the blood, the higher the degree of depression."

Folic acid can also help ward off dementia, according to Patrick Quillin in Beating Cancer With Nutrition, who wrote that experts estimate up to 20 percent of senility in older adults is simply the result of a long-term deficiency of folic acid and vitamin B-12, which can be aided by taking supplements. However, when taking folic acid supplements, it is important to remember that folic acid and vitamin B-12 work most effectively together, so you should make sure you are getting enough vitamin B-12, as well. Vegans often struggle with this balance since their diets are very rich in folic acid but not in B-12.

The meager representation of folic acid in the American diet can be increased if we all just take a little more care in planning our meals. One way to up folic acid consumption is to make sure your diet includes raw foods, since heat from cooking easily destroys folic acid. And remember, sources of folic acid are plentiful – soybeans, spinach, broccoli, cabbage, peanuts, asparagus, citrus fruits, brussels sprouts, avocado, sunflower seeds, orange juice and don't forget those leafy greens – we just have to be willing to integrate these foods into our diets.

And who wouldn't be willing? After all, some added folic acid could go a long way in helping keep your nervous and circulatory systems in check, while also protecting your body from cancer and heart problems, as well as promoting healthy fetal development in babies. Folic acid is something we need at all stage of life, so we owe it to ourselves to get enough.

The experts speak on folic acid

General information on folic acid

A study is available from the Washington Council for Responsible Nutrition that reports women taking Vitamin E over age 50 and folic acid and Zinc during childbearing years would save Medicare 11 billion dollars, and overall reduce birth defects and coronary heart disease hospital expenses of 20 billion dollars per year.
Anti-Aging Manual by Joseph B Marion, page 100

WHAT IS IT? Even though your body needs only comparatively minuscule amounts of folic acid, it is a vital nutrient. Folic acid—along with all the other nutrients, of course—is your guarantee of optimum physical and mental health. Your levels of folic acid are dependent on outside sources; your body does not make it on its own. Furthermore, it needs vitamin C to work properly. It works in partnership with B12 and B6, as well as the other B vitamins. Folic acid is essential to the production of norepinephrine and serotonin, chemical go-betweens of the nervous system.
Complete Guide Health Nutrition by Gary Null, page 284

Folic acid is one of the B vitamins that is crucial for the synthesis of DNA (genetic material) as well as for many other important cell functions. It was discovered in spinach leaves in 1941 and was named "folate," after the Latin word for leaf (folium). The terms folate and folic acid are roughly synonymous. For the sake of simplicity, I will generally use the latter term. Not surprisingly, this vitamin is mainly found in green leafy vegetables. Although folic acid is not an antioxidant, it boosts the antioxidant network and thus has a place in our story.
Antioxidants Against Cancer by Ralph Moss PhD, page 92

WHO NEEDS folic acid? If you are pregnant, elderly, or suffer from any sort of nervous disorder, you may benefit from additional amounts of folic acid in your diet. Pregnant women, for instance, must be wary of folic acid deficiency. Folic acid supplementation has been helpful in preventing abortion and miscarriage. The elderly need additional folic acid, too. If you are over sixty and depressed, withdrawn, and chronically tired, you may be deficient in this vital element. Let's look at the results of a study in which folic acid was added to the diets of elderly individuals: three groups of patients were used, all with varying degrees of circulation problems. The first group, those with the least degree of difficulty, experienced improved vision less than an hour after receiving folic acid. (Among those with circulatory problems, vision is often impaired because of poor circulation to the optical tissues.)
Complete Guide Health Nutrition by Gary Null, page 284

Folic acid: a water-soluble vitamin of the B complex essential for the synthesis of nucleic acids and necessary for making red blood cells (hematopoiesis), so a deficiency of folic acid results in anemia. After absorption, it is successively reduced to dihydro-folic acid and then tetrahydrofolic acid, the parent compound of the derivatives that act as coenzyme carriers of one-carbon groups in various metabolic reactions.
Building Wellness with DMG by Roger V Kendall PhD, page 216

Red blood cells are built with Vitamins B-12, folic acid, and B6.
Anti-Aging Manual by Joseph B Marion, page 100

And remember, folic acid can be destroyed by exposure to heat and strong light.
Complete Guide Health Nutrition by Gary Null, page 286

Recommendations on folic acid
Doctors routinely advise women who are pregnant, or thinking of becoming pregnant, to supplement folic acid (a B vitamin also known as folate) as a means of safeguarding against birth defects such as spinal malformations.
Anti-Aging Prescriptions by James Duke PhD, page 219

It is becoming increasingly obvious that food supplementation is necessary to prevent cancer and other diseases. The prestigious Institute of Medicine (IOM) of the National Academy of Sciences in 1998 called for supplementation with folic acid and vitamin B12.
Antioxidants Against Cancer by Ralph Moss PhD, page 10

If you're concerned that your diet might not provide enough vitamin B6 and folic acid to prevent stroke, Dr. Lieberman suggests taking supplements of both nutrients. Aim for 300 milligrams of B6 and 800 micrograms of folic acid a day Vitamin B6 doses this high, however, should only be taken under medical supervision. Add E for extra protection.
Blended Medicine by Michael Castleman, page 10

Vegetarians owe it to themselves to be extra careful about their diets. As Richard W. Vilter, M.D., of the University of Cincinnati College of Medicine, warns, "Persons who eat absolutely no animal protein (called vegans) or extreme vegetarians have no source of vitamin B12, but much folic acid in their diets." Frequently in such subjects, neurologic abnormalities develop of the posterolateral column degeneration type. This is a situation analogous to a patient with pernicious anemia who is treated inadequately with a mixed vitamin capsule containing folic acid." There is another danger for those who abstain from animal foods, including dairy products: dietary deficiencies don't show up for five to ten years because the body is able to hold some B12 in reserve. Nerve damage may exist without signs of deficiency until it is too late. The result of degeneration of the nervous system and the spinal cord is so irreparable that death may be the result.
Complete Guide Health Nutrition by Gary Null, page 283

Benefits and uses of folic acid
Folic acid is important during the aging process because it provides nourishment for the brain. Folic acid supports the production of energy and the production of blood cells. Supplementing with folic acid may help in the treatment of depression.
Alternative Medicine by Burton Goldberg, page 321

Three to four hundred milligrams of vitamin B5 and 150 mg of B6 should be consumed on a daily basis, while prescriptions of folic acid can serve as natural hormone replacements. Adequate quantities of essential fatty acids should also be consumed because they act as natural hormone supplements, prevent cancer, and can alleviate the symptoms of aging.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 258

Folic acid, the synthetic form of the B vitamin folate, is incredibly important. For one thing, folate is a key regulator of an amino acid called homocysteine, a breakdown product of animal protein. A number of studies have connected high levels of homocysteine in the blood to arterial disease and heart attacks. Folate helps the body eliminate homocysteine from the blood. Recently, Dr. Howard Morrison, an epidemiologist in Ottawa, was able to make a direct connection between folate and heart disease. He looked at folate levels in the blood of 5,056 men who had participated in a nutrition study in the 1970s, and he found that those with low levels of the vitamin were 69 percent more likely to have died from heart problems in the years since. Folate also has been found to prevent neural tube defects (such as spina bifida and anencephaly) in babies, which are caused when this structure fails to form properly. The neural tube is the embryonic tissue that later becomes the brain and spinal cord. Apparently folic acid is essential to its proper development. Earlier this year, the Food and Drug Administration ordered pasta, rice, and flour makers to add folic acid to their foods as protection against birth defects.
Ask Dr Weil by Andrew Weil MD, page 98

Proper nutritional supplementation can significantly improve cardiovascular conditions, as well as prevent them from occurring in the first place. Useful nutrients include beta carotene; vitamins B3 (niacin), Be, B12, C, and E; folic acid; the minerals calcium, chromium, magnesium, potassium, and selenium; the amino acids L-arginine, L-taurine, and L-carnitine; coenzyme Q10; and pycnogenol.
Alternative Medicine by Burton Goldberg, page 771

According to some studies, folic acid has been helpful in relieving depression, even when used in dosages as low as 400 meg. It can also enhance cerebral circulation. One study showed that people with low levels of folic acid were twice as likely as people with adequate levels to have narrowed arteries in their necks. Psychiatric symptoms also appear to be much higher in people, particularly elderly people, who have low folic acid levels. In one study, low folic acid levels increased likelihood of dementia by 300 percent. folic acid is especially effective at breaking down the common chemical homocysteine, which is a neurotoxin. An appropriate daily dosage would be 400 meg, the amount found in many multiple vitamins.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 247

Folic acid: This is another member of the vitamin B family, found in abundance in liver, kidney, mushrooms, spinach, yeast and green leafy vegetables. It has been used for decades to prevent and treat certain forms of anemia. But folic acid also increases the production of white blood cells crucial in the defense against cancer. In the late 1980s, scientists at the University of Alabama Medical Center found that the folic acid in dark leafy vegetables, oranges and liver could act together with vitamin B to prevent injuries to lung tissue and retard the development of cancer among cigarette smokers. These researchers found that smokers whose lung cells were injured had low levels of both folic acid and vitamin B12. Since these nutrients are necessary to synthesize DNA, a deficiency of one or both of these vitamins could make cells more susceptible to the effects of carcinogens. These vitamins also offered protection against birth defects and cancerous changes in cervical cells.
Cancer Therapy by Ralph W Moss PhD, page 42

Floss one to two times daily and then rinse mouth (for one minute) with several mouthfuls of liquid folic acid (0.1% solution) and then swallow. In one study, 60 individuals with gingivitis rinsed for one minute two times daily and had beneficial results. If you cannot find liquid folic acid, buy folic acid crystals in 800 meg capsules, empty two capsules in water and use this to gargle.
Alternative Medicine by Burton Goldberg, page 1055

Lipotropic factors are compounds that promote the transportation and utilization of fats, and help prevent the accumulation of fat in the liver. They include methionine, choline, folic acid, and vitamin B12.
Cancer And Natural Medicine by John Boik, page 140

Folic acid helps against uric acid.
Anti-Aging Manual by Joseph B Marion, page 560

The four B vitamins that are most important for your brain are B12, B6, B3, and folic acid.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 246

The body uses 75-99% of its Calcium, with Phosphorus, Boron, Manganese, Silica, Magnesium, Copper, Zinc, Strontium; Protein; the Vitamins A, B-Complex, B6, folic acid, Vitamin C, Vitamin D, and Vitamin K to form bone tissue and teeth.
Anti-Aging Manual by Joseph B Marion, page 800

The primary nutritional building blocks of both neurotransmitters are the amino acids tyrosine and phenylalanine. To potentiate the action of these amino acids, folic acid, magnesium, and vitamins C and B can be taken.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 213

Part of the vitamin B complex, folic acid is necessary for synthesis of nucleic acids and formation of the heme component of hemoglobin in red blood cells.
Britannica Encyclopedia Volume One, page 674

[Folic acid] is especially helpful for patients with a history of breast cancer, cervical dysplasia, and smoking. For smokers, it cuts down on the adverse effects of nicotine on the lungs.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 84

Treatments using folic acid
Folic acid is also used in the treatment of cervical dysplasia, a pre-cancerous condition of the uterus, and for this reason is also given to women who take birth control pills or who are pregnant.
Alternative Medicine by Burton Goldberg, page 410

Nerves on edge? Folic acid can help. The Lancet, Britain's prestigious medical journal, reports, "In the past decade [however] there has been increasing interest in the role of folate [folic acid] in neuronal metabolism, in neuropsychiatric illness, and in antiepileptic and convulsant mechanisms." When a folic acid deficiency occurs, your nervous system suffers, because there is normally such a high folate concentration in your cerebrospinal fluid. In many psychiatric and geriatric patients with mental dysfunctions, deficiency is common. "This is a promising area for future research," The Lancet adds.
Complete Guide Health Nutrition by Gary Null, page 285

Dr. Aesoph adds that chromium aids in stabilizing the erratic blood sugar seen in alcoholic hypoglycemia, while choline and folic acid are also commonly cited as important supplements to assist in the body's recovery from addiction.
Alternative Medicine by Burton Goldberg, page 480

Homocysteinemia: Persons with elevated levels of homocysteine are at risk for arteriosclerosis. This can and should be corrected with adequate amounts of folic acid, B 12, pyridoxine, and trimethylglycine. The only way you can be sure you are getting adequate amount of therapy is to regularly monitor blood levels of homocysteine. Current estimates are that 30 to 40% of arterial disease is related to high levels of homocysteine.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 220

Vitamin B may help for premenstrual or mid-menstrual cycle acne. Coexisting gum problems suggest the need for folic acid.
Alternative Medicine by Burton Goldberg, page 988

[For] pins and needles in the legs, take folic acid and B-12.
Anti-Aging Manual by Joseph B Marion, page 1100

Take 5 grams Vitamin C, 1 gram Calcium. 1/2 gram Magnesium, 100 mg. B-Complex, extra B6, B-12. and folic acid (for severe depression, requires Vitamin C for absorption).
Anti-Aging Manual by Joseph B Marion, page 800

Find relief in folic acid. One study found that women who experienced problems with constipation had low levels of the B vitamin folic acid in their blood. When the women began taking folic acid supplements, all of their symptoms subsided. Try taking up to 5,000 micrograms a day until the condition subsides, advises clinical nutritionist Shari Lieberman, Ph.D. But check with your doctor first, since dosages of folic acid over 1,000 micrograms should only be taken under medical supervision.
Blended Medicine by Michael Castleman, page 11

Herpes may be helped overnight by chewing folic acid with 500 mg. L-Lysine twice daily, and Zinc tablets.
Anti-Aging Manual by Joseph B Marion, page 455

If agitation or hyperactivity is seen, it is recommended that folic acid should be given in the amount of two 800 microgram tablets for each 125 mg of DMG taken.
Building Wellness with DMG by Roger V Kendall PhD, page 116

Disease prevention with folic acid
Folic acid, a B vitamin, is now known to prevent neural tube defects like spina bifida, a serious abnormality of early fetal development. Unfortunately, by the time most women learn they are pregnant, the critical period has already passed. A major source of folic acid is the cooked greens recommended in the program (another is orange juice). If you are contemplating pregnancy or think there is any possibility that you could get pregnant, for insurance take a daily B-complex vitamin supplement providing 400 micrograms of folic acid.
8 Weeks To Optimum Health By Andrew Weil MD, page 222

Women taking 400 mg of folic acid also have a decreased risk of heart attack and protection against Alzheimer's Disease and stroke. After 15 years of 400 mg of folic acid there is a 75% reduction in the number of women who get colon cancer.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 19

According to University of Washington researchers, 13,500 to 50,000 deaths from cardiovascular disease could be prevented every year if everyone took folic acid (the supplement form of folate) every day. All you need is 200 micrograms a day.
Anti-Aging Prescriptions by James Duke PhD, page 145

SPINA BIFIDA. Failure of the spinal bones to close over nerves arising from the lower end of the spinal cord. May cause paralysis of the legs and incontinence. Associated with poverty, bad housing and is more common in Celtic races and among the sikhs. Most common cause is folic acid deficiency. Prevention only. A woman of childbearing age should increase her consumption of food rich in folic acid, such as Brussels sprouts, spinach, green beans, oranges, potatoes, wholemeal bread, yeast extract. New evidence suggests health is determined before birth by a mother's condition during pregnancy. The UK Department of Health advises 400 micrograms (0.4mg) folic acid until the twelfth week of pregnancy.
Bartrams Encyclopedia of Herbal Medicine by Thomas Bartram, page 25

Perhaps as much as 30 percent of all heart disease is directly caused by high homocysteine levels, he says. That's the bad news. The good news is that three B vitamins—folic acid, B6, and B12—can help convert homocysteine to methionine or cystine, thus protecting your heart. Dr. Baum recommends taking 800 to 1,000 micrograms of folic acid, 400 micrograms of vitamin B12, and 50 milligrams of vitamin B6 daily.
Alternative Cures by Bill Gottlieb, page 337

...Other nutrients may be equally critical to the prevention of osteoporosis. "Vitamin K, silicon, boron, folic acid, magnesium, and manganese all play a role in bone building and need to be consumed through diet or supplements," he says. To prevent osteoporosis, you must get sufficient levels and the proper ratio of these bone nutrients.
Alternative Medicine by Burton Goldberg, page 840

Sources of folic acid
Folic acid, a B vitamin found in green leafy vegetables, nuts, and whole grains, can prevent neural tube defects in fetuses.
Alternative Medicine by Burton Goldberg, page 866

Greens are high in vitamins and minerals, including iron and calcium in forms that the body can absorb and use more readily than supplements. For example, they are a major source of folic acid (folate), a B vitamin that regulates protein metabolism and offers significant protection against coronary heart disease. ("Folate" and "foliage" share the same root.)
8 Weeks To Optimum Health By Andrew Weil MD, page 141

Eat at least eight servings of fruits and vegetables each day. These high-fiber, low-fat foods are typically rich in folic acid and other B vitamins, which reduce the risk for heart disease by helping to prevent arterial blood clots.
Bottom Line Yearbook 2002 by Bottom Line Personnel, page 331

The leafy green that Popeye made famous is among the best plant sources of folate. All you need is 200 micrograms a day. You can get more than that from 1/2 cup of spinach (or lentils, pinto beans, lima beans, black-eyed peas, or sunflower seeds) or a cup or two of spinach soup. What a pleasant way to stave off stroke and heart attack! Of course, spinach and beans aren't the only great sources of folate. Others include parsley, cabbage, asparagus, broccoli, brussels sprouts, endive, okra, avocado, peanuts, sunflower seeds, and orange juice.
Anti-Aging Prescriptions by James Duke PhD, page 145

A major source of folic acid is the cooked greens recommended in the program (another is orange juice).
8 Weeks To Optimum Health By Andrew Weil MD, page 222

Beetroot is rich in potassium, folic acid, and the antioxidant glutathione.
Alternative Medicine by Burton Goldberg, page 173

Legumes: Peas and beans, such as kidney, lima, soybean, navy, black, and lentils, are loaded with protein, folic acid, and amino acids.
Alternative Medicine by Burton Goldberg, page 192

Diets rich in folic acid and B vitamins would turn out to have such powerful benefits for the heart that they could outweigh such "sins" as moderate red meat intake. Could the public be blamed for its confusion?
Betrayal Of Trust By Laurie Garrett, page 394

Folic acid—This substance protects against cervical cancer and is necessary for proper synthesis of RNA and DNA. It is found in beets, cabbage, dark leafy vegetables, eggs, dairy products, citrus fruits, and most fish.
Alternative Medicine by Burton Goldberg, page 591

Dietary folate sources include leafy and dark green vegetables, citrus fruits, cereals, beans, poultry, and egg yolks, but free folic acid occurs only in supplements.
Britannica Encyclopedia Volume One, page 674

Folic acid [is] found in whole grains, chickpeas, soybeans, spinach, broccoli, and cabbage)…
Alternative Medicine by Burton Goldberg, page 745

Probiotics help suppress the growth of yeast, improve digestion by increasing the production of some enzymes, produce acids that fight bacteria, and manufacture nutrients such as vitamins K, Bi, B2, B3, B12, and folic acid.
Alternative Medicine by Burton Goldberg, page 908

Foods rich in folic acid include spinach and other dark green leafy vegetables, broccoli, asparagus, and whole wheat.
Blended Medicine by Michael Castleman, page 10

Many women have also long esteemed certain wild mushrooms, which some thought to be special gifts from Mother Earth. As we now know, naturally grown mushrooms (as opposed to commercial mushrooms grown in the dark) contain folic acid, which helps to prevent birth defects. These delicious and abundant choices, which do not have any poisonous look-alikes, can be eaten when they are underripe.
American Indian Healing Arts by E.Barrie Kavasch and Karen Baar, page 146

Folic acid deficiencies
Folic acid may be the most common vitamin deficiency in the world, since more people are choosing animal foods (poor source of folic acid) over plant foods. The name, folic acid, comes from the Latin term "folium", meaning foliage, since dark green leafy vegetables are a rich source of folic acid. Other good sources of folic acid include brewer's yeast, legumes, asparagus, oranges, cabbage, root vegetables and whole grains. Since folic acid is essential for all new cell growth, disturbances in folic acid metabolism are far reaching, including heart disease (due to more homocysteine in the blood), birth defects, immune suppression, cancer, premature senility and a long list of other conditions. Without adequate folate in the diet, cell growth is like a drunk driver heading down the highway—more likely to do some harm than not.
Beating Cancer With Nutrition by Patrick Quillin, page 180

Birth Control Pills: These pills produce folic acid deficiency. Where there is a lack of folic acid, homocysteine blood levels rise and this is associated with osteoporosis.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 130

Men Need folic acid too. Low folic acid levels in men are associated with low sperm count. A recent study has led investigators to hypothesize that low folic acid could also damage the DNA that sperm carry—which could lead to chromosomal damage in a fetus. Self-defense: Eat plenty of folate-rich fruits and vegetables and fortified grain products.
Bottom Line Yearbook 2004 by Bottom Line Personnel, page 334

B12 anemia is often accompanied by folic acid anemia. One of the reasons folic acid is important is that it fosters healthy prenatal development: It aids in the prevention of birth defects, such as those of the neural tube, and is crucial for proper cell production in the growing fetus. Folic acid is easily consumed by heat; hence, diets that consist primarily of cooked foods, with few raw foods included, often result in this type of deficiency. In addition, young children may develop a folic acid deficiency if they are given goat's milk. (Although superior to cow's milk in many ways, goat's milk lacks folic acid.) Teenagers and adults who are vegetarians may also fall victim to this form of anemia if they do not carefully balance their diets. Finally, folic acid anemia can be induced by alcoholism, which completely drains the body of this nutrient, and by the consumption of certain prescription drugs, such as oral contraceptives and anticancer drugs.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 32

Experts have estimated that up to 20% of all senility in older adults is merely a long term deficiency of folic acid and vitamin B-12. The RDA of folate is 200 meg for adults and 400 meg for pregnant women, although the Center for Disease Control has recommended that 800 meg of folic acid would prevent most cases of spinal bifida. Without adequate folic acid in the body, there is a buildup of homocysteine in the blood, which probably generates 10% or more of the 1 million cases of heart disease each year in the U.S.
Beating Cancer With Nutrition by Patrick Quillin, page 180

Deficiencies of folic acid and vitamin B12 may cause some cases of recurrent canker sores, says Flora Parsa Stay, D.D.S., a dentist in Oxnard, California. If you have recurrent sores, she recommends taking 400 micrograms of folic acid and 200 micrograms of vitamin B12 daily.
Alternative Cures by Bill Gottlieb, page 142

Persons with AIDS are often deficient in folic acid, selenium, zinc, and iron.
Alternative Medicine by Burton Goldberg, page 497

Deficiencies in vitamins B6, B12, and folic acid can trigger such neurological changes as a drop in alertness and memory ability as well as numbness and tingling in the legs.
BioMarkers by Williams Evans PhD and Irwin H Rosenberg MD, page 250

Reduced levels of certain vitamins, minerals, and amino acids have been tentatively linked with Alzheimer's, including folic acid, niacin (vitamin B3), thiamin (vitamin Bi), vitamins Be, B12, C, D, and E, magnesium, selenium, zinc, and tryptophan.
Alternative Medicine by Burton Goldberg, page 524

The elderly generally are deficient in Calories, Protein, Iron, Vitamins A and C, Calcium, the B-Complex, especially B-12 and folic acid, and that's with 70% of the elderly in institutions where the diets are carefully planned.
Anti-Aging Manual by Joseph B Marion, page 315

Low levels of folic acid, vitamin B12, pyridoxine, iron, and magnesium are some of the most commonly implicated nutritional influences on depression.
Beat Depression with St John's Wort by Steven Bratman, page 103

[Folate] anemia resulting from too little folic acid, needed for red-blood-cell maturation (see erythrocyte). White-cell and platelet levels are also often low. Progressive gastrointestinal problems develop. It may result from poor diet or from malabsorption, cirrhosis of the liver, or anticonvulsant drugs; it may also occur in the last three months of pregnancy and in severe hemolytic anemia (in which red cells break down). The blood profile resembles that of pernicious anemia. Taking folic acid causes rapid improvement; an adequate diet cures cases caused by malnutrition.
Britannica Encyclopedia Volume One, page 674

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http://www.naturalnews.com/016208.html

Mark said...

Preliminary Rebuttal to Recent Attacks Against Dietary Supplements

By William Faloon

The media recently ran headline news stories claiming that vitamins C, D and E do not prevent heart attack, stroke or breast cancer.

This report represents Life Extension’s preliminary response to these media attacks that are based on egregiously flawed studies.

We will submit this report for formal peer review and referencing and expect to post our official report within a few weeks.

Needless to say, when these biased attacks are launched, we are not given prior notice so that our side of the story makes it into the mass media.

In the early 1990s, several large population studies showed significant reductions in cardiovascular disease in those who consumed vitamin C or vitamin E.

The most widely reported study emanated from UCLA, where it was announced that men who took 800 mg a day of vitamin C lived six years longer than those who consumed the recommended daily allowance of 60 mg a day. The study, which evaluated 11,348 participants over a 10-year period of time, showed that higher vitamin C intake reduced cardiovascular disease mortality by 42%.

These kinds of findings did not go unnoticed by the federal government, who subsequently invested hundreds of millions of dollars in an attempt to ascertain if relatively modest vitamin doses could prevent common age-related diseases.

In a study that received extensive media coverage, four groups of male doctors were given various combinations of vitamin C and/or vitamin E or placebo. After eight years, there was no reported difference in heart attack or stroke incidence among the groups. This led the media to state that consumers should not buy these supplements.

As you will read, there were so many egregious flaws in this study that the findings are rendered meaningless. Regrettably, consumers who trust their lives to the mainstream media may fall victim to this latest charade to discredit validated methods to reduce cardiovascular disease risk.
Do you take your vitamins every other day?

The study subjects in the vitamin E groups were told to take one 400 IU capsule of synthetic alpha tocopherol every other day. This design flaw raises several issues that are rather obvious to serious supplement takers.

First of all, we don’t take our vitamins every other day. Free radicals are constantly being generated in our bodies, and supplement users today seek to take their antioxidants with most meals, as oxidative damage is generally the greatest after eating.

It is rather ludicrous to think that these study subjects would reduce their vascular disease risk by taking modest dose, every other day, of a form of vitamin E with inferior anti-oxidant capacity.

If one were to rely only on synthetic alpha tocopherol, the minimum daily dose needed has been shown to exceed 800 IU, far greater than the 400 IU ingested every other day by the subjects in this poorly designed study.

Serious supplement users normally take 400 IU every day of natural vitamin E along with a plethora of complimentary nutrients. We would not expect 400 IU of synthetic vitamin E taken every other day to produce much of an effect. Yet that is the dose given to these study subjects with the expectation that this would show a reduction in cardiovascular disease. This is by no means the only flaw of this study.
Natural versus synthetic vitamin E

There was a long standing debate as to whether natural or synthetic vitamin E is better. For most vitamins, there is no difference between natural and synthetic. In fact, for most vitamins, the only forms available are synthetic. With vitamin E, however, the natural form has proven far superior.

Natural vitamin E is distributed through the body much better than the synthetic form. The reason is that specific carrier proteins in the liver selectively bind to natural vitamin E and transport it through the blood to cells throughout the body. These carrier proteins only recognize a portion of synthetic vitamin E and ignore the remainder.

Japanese researchers gave natural or synthetic vitamin E to young women to measure how much vitamin E actually made it into their blood. It took only 100 mg (149 IU) of natural vitamin E to produce blood levels that required 300 mg (448 IU) of synthetic vitamin E.

Most studies show that synthetic vitamin E is only half as active in the body as the natural form. As it relates to the flawed study claiming that vitamin E does not prevent heart attack, the 400 IU of synthetic alpha tocopherol given every other day equates to only 100 IU a day of the natural form.

We would not expect 100 IU of natural vitamin E a day by itself to necessary reduce vascular disease risk. As you continue to read, however, there are many other flaws in this study that render its conclusions useless.

Note: When checking vitamin labels, natural vitamin E is usually stated as the “d” form (for example d-alpha tocopheryl acetate,d-alpha tocopherol, and d-alpha tocopheryl succinate). Synthetic vitamin E will have a “l” after the “d” (for example, dl-alpha tocopheryl acetate, dl-alpha tocopheryl succinate, dl-alpha tocopherol). Remember – “dl” signifies synthetic vitamin E, whereas “d” signifies natural vitamin E. Remember that if you are getting 400 IU of natural d-alpha tocopherol (d-alpha tocopheryl succinate or acetate) it is equal to about 800 IU of synthetic dl-tocopherol (dl-alpha tocopheryl acetate or succinate).
Vitamin C potencies too low

If all you are going to take to protect against free radical damage is vitamin E and/or vitamin C, then you will need far greater potencies than were given to the study subjects in this flawed study.

Published studies that document vascular benefits in response to vitamin C typically use doses of 1,000-6,000 mg each day. The authors of the flawed study alluded to this when they stated:

“In a pooled analysis of 9 cohorts, vitamin C supplement use exceeding 700 mg/day was significantly associated with a 25% reduction in coronary heart disease risk.”

Since the doctors who designed the flawed study knew that vitamin C intakes exceeding 700 mg a day significantly reduce heart attack rates, we can not figure out why they limited their subject’s daily dose to only 500 mg.

Two-time Nobel Prize laureate Linus Pauling and his associates advocated daily doses of vitamin C ranging from 10,000 to 20,000 mg to protect against heart attack. Linus Pauling’s theory was that atherosclerosis is primarily caused by insufficient vitamin C intake. Dr. Pauling compared the high amount of vitamin C naturally synthesized in the bodies of animals that don’t typically die of heart attacks. A 150 pound goat, for example will maintain an ascorbate blood concentration equivalent to ingesting 13,000 mg of vitamin C.

Unlike most animals, humans lack an internal enzyme needed to manufacture vitamin C in their body. If humans don’t obtain enough vitamin C from external sources, they die acutely from scurvy, or according to Linus Pauling…slowly suffer atherosclerotic occlusion. Dr. Pauling crusaded to educate humans about the need to take mega-doses of vitamin C.

Dr. Pauling and his associates published papers stating that when vitamin C levels are insufficient, the body uses cholesterol to repair the inner lining of arteries. Dr. Pauling believed that cholesterol’s involvement in atherosclerosis was a direct result of insufficient vitamin C.

Life Extension has long recommended that its members take at least 2,000 mg a day of vitamin C, along with potent plant extracts to enhance the biological benefits of ascorbate inside the body. The 500 mg daily dose of vitamin C given to the subjects of this flawed study was clearly inadequate. This did not stop the headline-hungry media and many conventional doctors from recommending that aging humans avoid these supplements altogether.

As we noted already, the dose of vitamin E used in this study was also too low to expect a reduction in vascular disease events. While alpha tocopherol vitamin E is a classic antioxidant, its free radical quenching efficacy pales in comparison to polyphenol extracts from green tea, pomegranate, grape-seed and blueberry.

Based on the superior antioxidant properties of plant extracts such as pomegranate, health conscious people today are able to obtain greater protection against free radicals and enhance the efficacy of the vitamin C without necessarily having to take the mega-doses recommended by Linus Pauling. On the flip-side, to attack the value of vitamin C based on a group of doctors who took only 500 mg a day does not correspond to the doses scientific studies show are needed to prevent heart attack.
Alpha tocopherol displaces gamma tocopherol

An increasing number of scientists are questioning the wisdom of administering alpha tocopherol vitamin E by itself. The reason is that alpha tocopherol displaces critically important gamma tocopherol in the body. The authors of the flawed study admitted that the failure to include gamma tocopherol may have been a reason that no effect was seen in the alpha tocopherol groups. Here is a quote directly from the flawed study:

"Moreover, PHS II and other prevention trials have used alpha-tocopherol, whereas the gamma-tocopherol isomer also may have a role in cardiovascular disease prevention because it has greater efficacy than alpha-tocopherol to inhibit lipid peroxidation and it may be suppressed in the presence of alpha-tocopherol."

The above admission understates the critical importance that gamma tocopherol plays in maintaining arterial health. While alpha tocopherol helps protect against lipid peroxidation, gamma tocopherol is required to neutralize the dangerous peroxynitrite free radical. Peroxnitrite damages arteries because:

1. Peroxnitrite promotes the oxidation of alpha tocopherol, thereby depleting the body of the vitamin E needed to protect against oxidation of the lipid moiety (part) of LDL. LDL is composed of both lipid and protein parts (moieties), and oxidation associated with both moieties has been implicated in atherosclerosis. In a fascinating paradox, when alpha tocopherol is given without gamma tocopherol, the result is that alpha tocopherol itself can be neutralized in the body by the peroxynitrite free radical. This in turn promotes oxidation of the lipid moiety of LDL , a major step on the path towards atherosclerosis.
2. Peroxnitrite promotes LDL protein oxidation. While alpha tocopherol inhibits LDL lipid peroxidation, gamma tocopherol is needed to protect against oxidation of the protein moiety (part) of LDL.

In the absence of gamma tocopherol, which can occur when alpha tocopherol is given without gamma tocopherol, both LDL lipid and protein oxidation is increased, which reveals the egregious mistake of trying to prevent vascular disease by administering only alpha tocopherol. Health conscious individuals should be assured that other nutrients such a lipoic acid and polyphenol plant extracts also block protein and lipid LDL oxidation.
Some studies suggest that only gamma tocopherol prevents heart attacks. As it relates to atherosclerosis,